| Field | Description |
|---|---|
| SampleID | Name of the sample |
| TrimReads | Total number of reads after quality filtering |
| MeanReadLen | Average read length after quality filtering |
| Contigs | Number of contigs of the draft genome (>200bp) |
| GenomeLength | Length (bp) of the draft genome |
| LargestContig | Length (bp) of the largest contig in the genome |
| N50 | Length of the smallest contig in the set that contains the fewest (largest) contigs whose combined length represents at least 50% of the assembly |
| GC-Content | GC content (%) of the draft genome |
| Depth | Number of times each nucleotide position in the draft genome has a read that aligns to that position |
| SampleID | TrimReads | MeanReadLen | Contigs | GenomeLength | LargestContig | N50 | GC-Content | Depth |
|---|---|---|---|---|---|---|---|---|
| ID005zero | 447672 | 129 | 70 | 4993383 | 556160 | 211386 | 50.60 | 11X |
| ID008 | 146 | 143 | 45 | 14384 | 415 | 358 | 50.15 | 1X |
| ID009 | 445827 | 137 | 647 | 5264283 | 116466 | 16469 | 57.36 | 11X |
| ID011 | 419430 | 133 | 323 | 5149794 | 151142 | 60552 | 50.75 | 10X |
| ID013 | 419323 | 132 | 2235 | 5680236 | 50661 | 4337 | 50.83 | 9X |
| ID014at24 | 402967 | 131 | 3801 | 7480294 | 39874 | 2836 | 50.64 | 7X |
| ID015HW | 417149 | 132 | 127 | 4946518 | 258577 | 101369 | 50.83 | 11X |
| ID015at48 | 348445 | 134 | 141 | 4946083 | 261874 | 77897 | 50.83 | 9X |
| ID016at24 | 376407 | 134 | 164 | 5066617 | 206105 | 69000 | 50.76 | 9X |
| ID017at48 | 265213 | 137 | 281 | 5060662 | 148849 | 43286 | 50.71 | 7X |
| ID018at24 | 332021 | 133 | 112 | 5053728 | 322917 | 114340 | 50.53 | 8X |
| ID020at24 | 321023 | 133 | 150 | 4694658 | 304850 | 83486 | 50.63 | 9X |
| ID021at24 | 437154 | 132 | 149 | 4781760 | 208787 | 59208 | 50.64 | 12X |
| ID025III | 47954 | 138 | 5432 | 5396283 | 7641 | 1066 | 53.02 | 1X |
| ID025II | 409299 | 134 | 165 | 5064739 | 234487 | 77657 | 50.76 | 10X |
| ID025I | 361054 | 132 | 133 | 5074111 | 342735 | 98841 | 50.77 | 9X |
| ID026 | 306128 | 128 | 133 | 5093392 | 293921 | 97680 | 50.72 | 7X |
| ID027 | 457381 | 129 | 151 | 5083310 | 252391 | 97639 | 50.74 | 11X |
| ID031 | 424851 | 132 | 91 | 5277895 | 439752 | 172240 | 50.57 | 10X |
| ID032I | 371633 | 130 | 89 | 5249727 | 330993 | 158921 | 50.66 | 9X |
| ID033I | 419857 | 129 | 131 | 4526608 | 244172 | 79601 | 50.73 | 11X |
| ID034II | 407964 | 131 | 131 | 5072404 | 280895 | 106187 | 50.77 | 10X |
| ID034I | 508184 | 133 | 141 | 5081530 | 254507 | 97496 | 50.74 | 13X |
| ID037 | 337693 | 132 | 149 | 4757913 | 225519 | 61221 | 50.78 | 9X |
| ID043I | 377261 | 133 | 114 | 5131371 | 345412 | 117539 | 50.59 | 9X |
| ID045 | 319002 | 132 | 112 | 5080013 | 283826 | 147986 | 50.64 | 8X |
| ID047 | 335646 | 130 | 150 | 5226487 | 452233 | 102284 | 50.63 | 8X |
| ID050 | 531211 | 130 | 118 | 4897826 | 311054 | 106189 | 50.72 | 14X |
| ID051 | 311902 | 133 | 4256 | 6328658 | 38558 | 1853 | 50.21 | 6X |
| ID052 | 414620 | 132 | 171 | 5411328 | 295749 | 85770 | 50.48 | 10X |
| ID057 | 76108 | 134 | 142 | 4831648 | 201994 | 67497 | 50.64 | 2X |
| ID058 | 310873 | 132 | 2480 | 5006051 | 48769 | 2892 | 50.48 | 8X |
| ID066 | 457516 | 130 | 113 | 5009011 | 371379 | 179450 | 50.90 | 11X |
| ID070 | 401224 | 130 | 153 | 4932282 | 417517 | 83079 | 50.78 | 10X |
| ID073 | 380771 | 133 | 210 | 4913690 | 229261 | 59510 | 50.76 | 10X |
| ID081 | 352398 | 132 | 141 | 4937691 | 306082 | 83508 | 50.67 | 9X |
| ID096I | 344533 | 137 | 358 | 5445707 | 100747 | 32529 | 57.15 | 8X |
| ID098 | 317029 | 133 | 721 | 5685500 | 149812 | 33837 | 50.40 | 7X |
| ID099 | 434039 | 133 | 136 | 4655534 | 221218 | 88674 | 50.72 | 12X |
| ID24 | 322189 | 130 | 115 | 5086874 | 314853 | 125472 | 50.76 | 8X |
Average number of reads per sample = 359277
Average read length per sample = 133 bp
Average number of contigs per sample = 612
Average genome length per sample = 5034750 bp
Average largest contig length per sample = 240554 bp
Average N50 per sample = 80279 bp
Average GC content per sample = 51.051%
Average sequencing depth = 8.85X
| Field | Description |
|---|---|
| GenomePosition | Position in the genome where SNP is found |
| Type | Nature of the SNP identified (Only ‘True’ SNPs are shown by default) |
| ReferenceAllele | Allele found in the reference genome |
| AlternateAllele | Allele found in the genome of interest forming the SNP |
| Consequence | Amino acid alterations caused by the SNP |
| AffectedGene | The tartget gene affected by the SNP |
| Product | The outcome from the presence of the SNP |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318124 | snp | A | G | missense_variant c.196T>C p.Tyr66His | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 743316 | snp | G | C | missense_variant c.490G>C p.Val164Leu | ybgI | radiation resistance protein YbgI |
| 1006557 | snp | C | T | missense_variant c.1044G>A p.Met348Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216402 | snp | A | T | missense_variant c.34A>T p.Thr12Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441532 | snp | C | T | missense_variant c.212G>A p.Ser71Asn | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620016 | snp | G | A | missense_variant c.28G>A p.Ala10Thr | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227353 | snp | A | G | missense_variant c.1406T>C p.Leu469Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227422 | snp | G | C | missense_variant c.1337C>G p.Pro446Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227443 | snp | G | C | missense_variant c.1316C>G p.Ala439Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227476 | snp | C | G | missense_variant c.1283G>C p.Arg428Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227641 | snp | T | A | missense_variant c.1118A>T p.Gln373Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227767 | snp | G | A | missense_variant c.992C>T p.Ser331Phe | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227872 | snp | G | C | missense_variant c.887C>G p.Pro296Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227968 | snp | A | G | missense_variant c.791T>C p.Leu264Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228004 | snp | C | A | missense_variant c.755G>T p.Gly252Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228567 | snp | T | C | missense_variant c.192A>G p.Ile64Met | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228649 | snp | G | A | missense_variant c.110C>T p.Pro37Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228654 | snp | T | G | missense_variant c.105A>C p.Gln35His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630612 | snp | A | G | missense_variant c.287A>G p.Lys96Arg | yfgI | nalidixic acid resistance protein YfgI |
| 3635776 | snp | G | T | missense_variant c.936G>T p.Met312Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870310 | snp | T | A | missense_variant c.934T>A p.Trp312Arg | cbrA | colicin M resistance protein |
| 4102929 | snp | G | C | missense_variant c.108G>C p.Glu36Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| 4103326 | snp | G | A | missense_variant c.505G>A p.Val169Met | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
## Error in read.table("ID008_amr_snps", header = T, sep = "\t", dec = ".", : no lines available in input
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318124 | snp | A | G | missense_variant c.196T>C p.Tyr66His | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 743316 | snp | G | C | missense_variant c.490G>C p.Val164Leu | ybgI | radiation resistance protein YbgI |
| 1006557 | snp | C | T | missense_variant c.1044G>A p.Met348Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216402 | snp | A | T | missense_variant c.34A>T p.Thr12Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441532 | snp | C | T | missense_variant c.212G>A p.Ser71Asn | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620016 | snp | G | A | missense_variant c.28G>A p.Ala10Thr | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227353 | snp | A | G | missense_variant c.1406T>C p.Leu469Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227422 | snp | G | C | missense_variant c.1337C>G p.Pro446Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227443 | snp | G | C | missense_variant c.1316C>G p.Ala439Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227476 | snp | C | G | missense_variant c.1283G>C p.Arg428Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227641 | snp | T | A | missense_variant c.1118A>T p.Gln373Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227767 | snp | G | A | missense_variant c.992C>T p.Ser331Phe | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227872 | snp | G | C | missense_variant c.887C>G p.Pro296Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227968 | snp | A | G | missense_variant c.791T>C p.Leu264Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228004 | snp | C | A | missense_variant c.755G>T p.Gly252Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228567 | snp | T | C | missense_variant c.192A>G p.Ile64Met | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228649 | snp | G | A | missense_variant c.110C>T p.Pro37Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228654 | snp | T | G | missense_variant c.105A>C p.Gln35His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630612 | snp | A | G | missense_variant c.287A>G p.Lys96Arg | yfgI | nalidixic acid resistance protein YfgI |
| 3635776 | snp | G | T | missense_variant c.936G>T p.Met312Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870310 | snp | T | A | missense_variant c.934T>A p.Trp312Arg | cbrA | colicin M resistance protein |
| 4102929 | snp | G | C | missense_variant c.108G>C p.Glu36Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| 4103326 | snp | G | A | missense_variant c.505G>A p.Val169Met | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
## Error in read.table("ID009_amr_snps", header = T, sep = "\t", dec = ".", : no lines available in input
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318124 | snp | A | G | missense_variant c.196T>C p.Tyr66His | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 743316 | snp | G | C | missense_variant c.490G>C p.Val164Leu | ybgI | radiation resistance protein YbgI |
| 1006557 | snp | C | T | missense_variant c.1044G>A p.Met348Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216402 | snp | A | T | missense_variant c.34A>T p.Thr12Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441532 | snp | C | T | missense_variant c.212G>A p.Ser71Asn | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620016 | snp | G | A | missense_variant c.28G>A p.Ala10Thr | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227353 | snp | A | G | missense_variant c.1406T>C p.Leu469Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227422 | snp | G | C | missense_variant c.1337C>G p.Pro446Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227443 | snp | G | C | missense_variant c.1316C>G p.Ala439Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227476 | snp | C | G | missense_variant c.1283G>C p.Arg428Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227641 | snp | T | A | missense_variant c.1118A>T p.Gln373Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227767 | snp | G | A | missense_variant c.992C>T p.Ser331Phe | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227872 | snp | G | C | missense_variant c.887C>G p.Pro296Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227968 | snp | A | G | missense_variant c.791T>C p.Leu264Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228004 | snp | C | A | missense_variant c.755G>T p.Gly252Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228567 | snp | T | C | missense_variant c.192A>G p.Ile64Met | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228649 | snp | G | A | missense_variant c.110C>T p.Pro37Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228654 | snp | T | G | missense_variant c.105A>C p.Gln35His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630612 | snp | A | G | missense_variant c.287A>G p.Lys96Arg | yfgI | nalidixic acid resistance protein YfgI |
| 3635776 | snp | G | T | missense_variant c.936G>T p.Met312Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870310 | snp | T | A | missense_variant c.934T>A p.Trp312Arg | cbrA | colicin M resistance protein |
| 4102929 | snp | G | C | missense_variant c.108G>C p.Glu36Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| 4103326 | snp | G | A | missense_variant c.505G>A p.Val169Met | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1441517 | snp | A | T | missense_variant c.227T>A p.Leu76Gln | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441697 | snp | C | T | missense_variant c.47G>A p.Gly16Glu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 4103456 | snp | G | A | missense_variant c.635G>A p.Gly212Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 318301 | snp | G | T | missense_variant c.19C>A p.Leu7Met | rclC | reactive chlorine species resistance protein C |
| 1006886 | snp | C | T | missense_variant c.715G>A p.Gly239Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007267 | snp | C | T | missense_variant c.334G>A p.Gly112Arg | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1441604 | snp | C | T | missense_variant c.140G>A p.Ser47Asn | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630642 | snp | G | A | missense_variant c.317G>A p.Arg106His | yfgI | nalidixic acid resistance protein YfgI |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 318301 | snp | G | T | missense_variant c.19C>A p.Leu7Met | rclC | reactive chlorine species resistance protein C |
| 1006886 | snp | C | T | missense_variant c.715G>A p.Gly239Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007267 | snp | C | T | missense_variant c.334G>A p.Gly112Arg | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1441604 | snp | C | T | missense_variant c.140G>A p.Ser47Asn | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630642 | snp | G | A | missense_variant c.317G>A p.Arg106His | yfgI | nalidixic acid resistance protein YfgI |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318124 | snp | A | G | missense_variant c.196T>C p.Tyr66His | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 743316 | snp | G | C | missense_variant c.490G>C p.Val164Leu | ybgI | radiation resistance protein YbgI |
| 1006557 | snp | C | T | missense_variant c.1044G>A p.Met348Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216402 | snp | A | T | missense_variant c.34A>T p.Thr12Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441532 | snp | C | T | missense_variant c.212G>A p.Ser71Asn | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620016 | snp | G | A | missense_variant c.28G>A p.Ala10Thr | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227353 | snp | A | G | missense_variant c.1406T>C p.Leu469Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227422 | snp | G | C | missense_variant c.1337C>G p.Pro446Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227443 | snp | G | C | missense_variant c.1316C>G p.Ala439Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227476 | snp | C | G | missense_variant c.1283G>C p.Arg428Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227641 | snp | T | A | missense_variant c.1118A>T p.Gln373Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227767 | snp | G | A | missense_variant c.992C>T p.Ser331Phe | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227872 | snp | G | C | missense_variant c.887C>G p.Pro296Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227968 | snp | A | G | missense_variant c.791T>C p.Leu264Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228004 | snp | C | A | missense_variant c.755G>T p.Gly252Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228567 | snp | T | C | missense_variant c.192A>G p.Ile64Met | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228649 | snp | G | A | missense_variant c.110C>T p.Pro37Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228654 | snp | T | G | missense_variant c.105A>C p.Gln35His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630612 | snp | A | G | missense_variant c.287A>G p.Lys96Arg | yfgI | nalidixic acid resistance protein YfgI |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870310 | snp | T | A | missense_variant c.934T>A p.Trp312Arg | cbrA | colicin M resistance protein |
| 4102929 | snp | G | C | missense_variant c.108G>C p.Glu36Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| 4103326 | snp | G | A | missense_variant c.505G>A p.Val169Met | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007259 | snp | G | C | missense_variant c.342C>G p.Phe114Leu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216436 | snp | C | T | missense_variant c.68C>T p.Ser23Leu | ariR | regulator of acid resistance, influenced by indole |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1501490 | snp | T | G | missense_variant c.918T>G p.Phe306Leu | tehA | tellurite resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228307 | snp | C | T | missense_variant c.452G>A p.Gly151Asp | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228496 | snp | A | C | missense_variant c.263T>G p.Phe88Cys | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318124 | snp | A | G | missense_variant c.196T>C p.Tyr66His | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 1006557 | snp | C | T | missense_variant c.1044G>A p.Met348Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006753 | snp | A | G | missense_variant c.848T>C p.Ile283Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1169089 | snp | C | A | missense_variant c.17C>A p.Thr6Asn | bhsA | DUF1471 domain-containing multiple stress resistance outer membrane protein BhsA |
| 1216402 | snp | A | T | missense_variant c.34A>T p.Thr12Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620016 | snp | G | A | missense_variant c.28G>A p.Ala10Thr | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 1620106 | snp | C | A | missense_variant c.118C>A p.Pro40Thr | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227429 | snp | C | T | missense_variant c.1330G>A p.Glu444Lys | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227452 | snp | A | G | missense_variant c.1307T>C p.Leu436Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227570 | snp | C | T | missense_variant c.1189G>A p.Gly397Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227968 | snp | A | G | missense_variant c.791T>C p.Leu264Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228004 | snp | C | A | missense_variant c.755G>T p.Gly252Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228530 | snp | T | C | missense_variant c.229A>G p.Thr77Ala | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228556 | snp | A | G | missense_variant c.203T>C p.Leu68Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228628 | snp | G | A | missense_variant c.131C>T p.Ala44Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228689 | snp | G | T | missense_variant c.70C>A p.Pro24Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 3869486 | snp | G | A | missense_variant c.110G>A p.Cys37Tyr | cbrA | colicin M resistance protein |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870310 | snp | T | A | missense_variant c.934T>A p.Trp312Arg | cbrA | colicin M resistance protein |
| 4102929 | snp | G | C | missense_variant c.108G>C p.Glu36Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318312 | snp | T | C | missense_variant c.8A>G p.Lys3Arg | rclC | reactive chlorine species resistance protein C |
| 742927 | snp | C | T | missense_variant c.101C>T p.Thr34Met | ybgI | radiation resistance protein YbgI |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006933 | snp | C | T | missense_variant c.668G>A p.Gly223Asp | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007131 | snp | T | G | missense_variant c.470A>C p.Asp157Ala | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216402 | snp | A | T | missense_variant c.34A>T p.Thr12Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1501299 | snp | C | T | missense_variant c.727C>T p.Arg243Cys | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620016 | snp | G | A | missense_variant c.28G>A p.Ala10Thr | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227452 | snp | A | C | missense_variant c.1307T>G p.Leu436Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227908 | snp | G | A | missense_variant c.851C>T p.Ala284Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227935 | snp | T | A | missense_variant c.824A>T p.Asn275Ile | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227949 | snp | A | C | missense_variant c.810T>G p.Ser270Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228109 | snp | C | G | missense_variant c.650G>C p.Arg217Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228145 | snp | C | T | missense_variant c.614G>A p.Cys205Tyr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228151 | snp | C | A | missense_variant c.608G>T p.Arg203Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228241 | snp | C | T | missense_variant c.518G>A p.Gly173Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228277 | snp | C | T | missense_variant c.482G>A p.Arg161Gln | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228367 | snp | C | A | missense_variant c.392G>T p.Arg131Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228406 | snp | C | A | missense_variant c.353G>T p.Arg118Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 4102929 | snp | G | C | missense_variant c.108G>C p.Glu36Asp | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227588 | snp | G | A | missense_variant c.1171C>T p.Arg391Trp | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3869407 | snp | C | A | missense_variant c.31C>A p.Leu11Ile | cbrA | colicin M resistance protein |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 1216484 | snp | C | A | missense_variant c.116C>A p.Thr39Asn | ariR | regulator of acid resistance, influenced by indole |
| 1441685 | snp | T | C | missense_variant c.59A>G p.Asn20Ser | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1441725 | snp | A | G | missense_variant c.19T>C p.Phe7Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1501490 | snp | T | G | missense_variant c.918T>G p.Phe306Leu | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620058 | snp | A | C | missense_variant c.70A>C p.Thr24Pro | marB | multiple antibiotic resistance protein |
| 1620086 | snp | C | G | missense_variant c.98C>G p.Ala33Gly | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635508 | snp | A | G | missense_variant c.668A>G p.His223Arg | yhiM | inner membrane protein with a role in acid resistance |
| 3869815 | snp | A | T | missense_variant c.439A>T p.Thr147Ser | cbrA | colicin M resistance protein |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 743181 | snp | A | T | missense_variant c.355A>T p.Thr119Ser | ybgI | radiation resistance protein YbgI |
| 1007522 | snp | C | T | missense_variant c.79G>A p.Val27Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007576 | snp | T | C | missense_variant c.25A>G p.Ile9Val | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441506 | snp | C | T | missense_variant c.238G>A p.Glu80Lys | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620022 | snp | C | T | missense_variant c.34C>T p.Leu12Phe | marB | multiple antibiotic resistance protein |
| 1620037 | snp | G | A | missense_variant c.49G>A p.Ala17Thr | marB | multiple antibiotic resistance protein |
| 1620046 | snp | G | A | missense_variant c.58G>A p.Val20Ile | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227326 | snp | G | A | missense_variant c.1433C>T p.Ala478Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227422 | snp | G | C | missense_variant c.1337C>G p.Pro446Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227443 | snp | G | C | missense_variant c.1316C>G p.Ala439Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227452 | snp | A | C | missense_variant c.1307T>G p.Leu436Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227563 | snp | G | A | missense_variant c.1196C>T p.Pro399Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227668 | snp | A | G | missense_variant c.1091T>C p.Val364Ala | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227935 | snp | T | A | missense_variant c.824A>T p.Asn275Ile | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227949 | snp | A | C | missense_variant c.810T>G p.Ser270Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228109 | snp | C | G | missense_variant c.650G>C p.Arg217Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228145 | snp | C | T | missense_variant c.614G>A p.Cys205Tyr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228151 | snp | C | A | missense_variant c.608G>T p.Arg203Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228190 | snp | G | A | missense_variant c.569C>T p.Ala190Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228502 | snp | C | T | missense_variant c.257G>A p.Ser86Asn | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630356 | snp | G | A | missense_variant c.31G>A p.Ala11Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 3635277 | snp | C | T | missense_variant c.437C>T p.Thr146Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3635534 | snp | T | A | missense_variant c.694T>A p.Phe232Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3869635 | snp | C | T | missense_variant c.259C>T p.Leu87Phe | cbrA | colicin M resistance protein |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870080 | snp | G | A | missense_variant c.704G>A p.Ser235Asn | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 4103121 | snp | G | T | missense_variant c.300G>T p.Met100Ile | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 317767 | snp | G | A | missense_variant c.553C>T p.Arg185Cys | rclC | reactive chlorine species resistance protein C |
| 317874 | snp | C | T | missense_variant c.446G>A p.Gly149Asp | rclC | reactive chlorine species resistance protein C |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1441734 | snp | C | G | missense_variant c.10G>C p.Val4Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1500807 | snp | C | A | missense_variant c.235C>A p.Leu79Met | tehA | tellurite resistance protein |
| 1501409 | snp | T | A | missense_variant c.837T>A p.Asp279Glu | tehA | tellurite resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6408 | snp | T | G | missense_variant c.52A>C p.Thr18Pro | yaaA | peroxide stress resistance protein YaaA |
| 317736 | snp | G | A | missense_variant c.584C>T p.Thr195Ile | rclC | reactive chlorine species resistance protein C |
| 317780 | snp | T | G | missense_variant c.540A>C p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 1006759 | snp | G | A | missense_variant c.842C>T p.Ala281Val | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1006832 | snp | C | T | missense_variant c.769G>A p.Val257Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1441506 | snp | C | T | missense_variant c.238G>A p.Glu80Lys | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620022 | snp | C | T | missense_variant c.34C>T p.Leu12Phe | marB | multiple antibiotic resistance protein |
| 1620037 | snp | G | A | missense_variant c.49G>A p.Ala17Thr | marB | multiple antibiotic resistance protein |
| 1620046 | snp | G | A | missense_variant c.58G>A p.Val20Ile | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227443 | snp | G | C | missense_variant c.1316C>G p.Ala439Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227452 | snp | A | C | missense_variant c.1307T>G p.Leu436Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227570 | snp | C | T | missense_variant c.1189G>A p.Gly397Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227935 | snp | T | A | missense_variant c.824A>T p.Asn275Ile | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227949 | snp | A | C | missense_variant c.810T>G p.Ser270Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228109 | snp | C | G | missense_variant c.650G>C p.Arg217Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228118 | snp | G | A | missense_variant c.641C>T p.Pro214Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228145 | snp | C | T | missense_variant c.614G>A p.Cys205Tyr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228190 | snp | G | A | missense_variant c.569C>T p.Ala190Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228367 | snp | C | A | missense_variant c.392G>T p.Arg131Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228406 | snp | C | A | missense_variant c.353G>T p.Arg118Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228530 | snp | T | C | missense_variant c.229A>G p.Thr77Ala | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228701 | snp | C | T | missense_variant c.58G>A p.Ala20Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630545 | snp | G | A | missense_variant c.220G>A p.Ala74Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630629 | snp | G | C | missense_variant c.304G>C p.Glu102Gln | yfgI | nalidixic acid resistance protein YfgI |
| 3635277 | snp | C | T | missense_variant c.437C>T p.Thr146Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3635534 | snp | T | A | missense_variant c.694T>A p.Phe232Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3869866 | snp | C | T | missense_variant c.490C>T p.His164Tyr | cbrA | colicin M resistance protein |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870058 | snp | A | G | missense_variant c.682A>G p.Thr228Ala | cbrA | colicin M resistance protein |
| 3870229 | snp | G | A | missense_variant c.853G>A p.Gly285Arg | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 4103121 | snp | G | T | missense_variant c.300G>T p.Met100Ile | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 6288 | snp | C | T | missense_variant c.172G>A p.Gly58Ser | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1500893 | snp | C | G | missense_variant c.321C>G p.Cys107Trp | tehA | tellurite resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630545 | snp | G | A | missense_variant c.220G>A p.Ala74Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630629 | snp | G | C | missense_variant c.304G>C p.Glu102Gln | yfgI | nalidixic acid resistance protein YfgI |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1006777 | snp | G | C | missense_variant c.824C>G p.Ala275Gly | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227767 | snp | G | A | missense_variant c.992C>T p.Ser331Phe | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227890 | snp | C | G | missense_variant c.869G>C p.Trp290Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227908 | snp | G | A | missense_variant c.851C>T p.Ala284Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228444 | snp | T | G | missense_variant c.315A>C p.Arg105Ser | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 3635534 | snp | T | A | missense_variant c.694T>A p.Phe232Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3635595 | snp | C | T | missense_variant c.755C>T p.Ala252Val | yhiM | inner membrane protein with a role in acid resistance |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 6408 | snp | T | G | missense_variant c.52A>C p.Thr18Pro | yaaA | peroxide stress resistance protein YaaA |
| 303216 | snp | A | G | missense_variant c.226A>G p.Ile76Val | yagU | inner membrane protein that contributes to acid resistance |
| 317780 | snp | T | G | missense_variant c.540A>C p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 743202 | snp | C | T | missense_variant c.376C>T p.Pro126Ser | ybgI | radiation resistance protein YbgI |
| 1006759 | snp | G | A | missense_variant c.842C>T p.Ala281Val | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007074 | snp | A | G | missense_variant c.527T>C p.Val176Ala | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216562 | snp | G | A | missense_variant c.194G>A p.Ser65Asn | ariR | regulator of acid resistance, influenced by indole |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1501518 | snp | G | A | missense_variant c.946G>A p.Val316Ile | tehA | tellurite resistance protein |
| 1501537 | snp | T | C | missense_variant c.965T>C p.Val322Ala | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620037 | snp | G | A | missense_variant c.49G>A p.Ala17Thr | marB | multiple antibiotic resistance protein |
| 1620046 | snp | G | A | missense_variant c.58G>A p.Val20Ile | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227422 | snp | G | C | missense_variant c.1337C>G p.Pro446Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227452 | snp | A | G | missense_variant c.1307T>C p.Leu436Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227818 | snp | G | A | missense_variant c.941C>T p.Pro314Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227935 | snp | T | A | missense_variant c.824A>T p.Asn275Ile | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227949 | snp | A | C | missense_variant c.810T>G p.Ser270Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227974 | snp | G | A | missense_variant c.785C>T p.Ala262Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228109 | snp | C | G | missense_variant c.650G>C p.Arg217Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228145 | snp | C | T | missense_variant c.614G>A p.Cys205Tyr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228151 | snp | C | A | missense_variant c.608G>T p.Arg203Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228256 | snp | A | T | missense_variant c.503T>A p.Val168Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228418 | snp | C | T | missense_variant c.341G>A p.Gly114Asp | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228530 | snp | T | C | missense_variant c.229A>G p.Thr77Ala | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228668 | snp | C | T | missense_variant c.91G>A p.Ala31Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635534 | snp | T | A | missense_variant c.694T>A p.Phe232Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3869447 | snp | G | A | missense_variant c.71G>A p.Gly24Asp | cbrA | colicin M resistance protein |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870058 | snp | A | G | missense_variant c.682A>G p.Thr228Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 4103121 | snp | G | T | missense_variant c.300G>T p.Met100Ile | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 6401 | snp | G | A | missense_variant c.59C>T p.Thr20Met | yaaA | peroxide stress resistance protein YaaA |
| 317737 | snp | T | C | missense_variant c.583A>G p.Thr195Ala | rclC | reactive chlorine species resistance protein C |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 318301 | snp | G | T | missense_variant c.19C>A p.Leu7Met | rclC | reactive chlorine species resistance protein C |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007596 | snp | G | A | missense_variant c.5C>T p.Ala2Val | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| 4103027 | snp | C | T | missense_variant c.206C>T p.Ala69Val | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| 4103116 | snp | T | C | missense_variant c.295T>C p.Tyr99His | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 303016 | snp | C | T | missense_variant c.26C>T p.Pro9Leu | yagU | inner membrane protein that contributes to acid resistance |
| 303486 | snp | G | C | missense_variant c.496G>C p.Val166Leu | yagU | inner membrane protein that contributes to acid resistance |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 6339 | snp | G | T | missense_variant c.121C>A p.Leu41Met | yaaA | peroxide stress resistance protein YaaA |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007270 | snp | T | G | missense_variant c.331A>C p.Ser111Arg | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007596 | snp | G | A | missense_variant c.5C>T p.Ala2Val | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1169131 | snp | G | A | missense_variant c.59G>A p.Ser20Asn | bhsA | DUF1471 domain-containing multiple stress resistance outer membrane protein BhsA |
| 1441734 | snp | C | G | missense_variant c.10G>C p.Val4Leu | hslJ | lipoprotein implicated in Novobiocin resistance |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1500807 | snp | C | A | missense_variant c.235C>A p.Leu79Met | tehA | tellurite resistance protein |
| 1501409 | snp | T | A | missense_variant c.837T>A p.Asp279Glu | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620037 | snp | G | A | missense_variant c.49G>A p.Ala17Thr | marB | multiple antibiotic resistance protein |
| 1620046 | snp | G | A | missense_variant c.58G>A p.Val20Ile | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228032 | snp | G | T | missense_variant c.727C>A p.Pro243Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630850 | snp | C | A | missense_variant c.525C>A p.Asp175Glu | yfgI | nalidixic acid resistance protein YfgI |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228463 | snp | G | A | missense_variant c.296C>T p.Pro99Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630642 | snp | G | A | missense_variant c.317G>A p.Arg106His | yfgI | nalidixic acid resistance protein YfgI |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620046 | snp | G | A | missense_variant c.58G>A p.Val20Ile | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227476 | snp | C | G | missense_variant c.1283G>C p.Arg428Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228100 | snp | G | A | missense_variant c.659C>T p.Ala220Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228331 | snp | A | T | missense_variant c.428T>A p.Val143Glu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228553 | snp | G | T | missense_variant c.206C>A p.Pro69His | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228701 | snp | C | T | missense_variant c.58G>A p.Ala20Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 3635117 | snp | G | A | missense_variant c.277G>A p.Ala93Thr | yhiM | inner membrane protein with a role in acid resistance |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870058 | snp | A | G | missense_variant c.682A>G p.Thr228Ala | cbrA | colicin M resistance protein |
| 3870160 | snp | G | A | missense_variant c.784G>A p.Val262Ile | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870276 | snp | A | C | missense_variant c.900A>C p.Leu300Phe | cbrA | colicin M resistance protein |
| 4103389 | snp | C | T | missense_variant c.568C>T p.Arg190Cys | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 6288 | snp | C | T | missense_variant c.172G>A p.Gly58Ser | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1500893 | snp | C | G | missense_variant c.321C>G p.Cys107Trp | tehA | tellurite resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630545 | snp | G | A | missense_variant c.220G>A p.Ala74Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630629 | snp | G | C | missense_variant c.304G>C p.Glu102Gln | yfgI | nalidixic acid resistance protein YfgI |
## Error in read.table("ID096I_amr_snps", header = T, sep = "\t", dec = ".", : no lines available in input
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 6288 | snp | C | T | missense_variant c.172G>A p.Gly58Ser | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1500893 | snp | C | G | missense_variant c.321C>G p.Cys107Trp | tehA | tellurite resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630545 | snp | G | A | missense_variant c.220G>A p.Ala74Thr | yfgI | nalidixic acid resistance protein YfgI |
| 2630629 | snp | G | C | missense_variant c.304G>C p.Glu102Gln | yfgI | nalidixic acid resistance protein YfgI |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 317780 | snp | T | A | missense_variant c.540A>T p.Glu180Asp | rclC | reactive chlorine species resistance protein C |
| 318076 | snp | T | A | missense_variant c.244A>T p.Thr82Ser | rclC | reactive chlorine species resistance protein C |
| 1007042 | snp | G | T | missense_variant c.559C>A p.Arg187Ser | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007428 | snp | G | A | missense_variant c.173C>T p.Thr58Ile | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1007587 | snp | A | G | missense_variant c.14T>C p.Ile5Thr | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 1216402 | snp | A | G | missense_variant c.34A>G p.Thr12Ala | ariR | regulator of acid resistance, influenced by indole |
| 1216417 | snp | G | T | missense_variant c.49G>T p.Ala17Ser | ariR | regulator of acid resistance, influenced by indole |
| 1216562 | snp | G | A | missense_variant c.194G>A p.Ser65Asn | ariR | regulator of acid resistance, influenced by indole |
| 1500615 | snp | G | A | missense_variant c.43G>A p.Gly15Ser | tehA | tellurite resistance protein |
| 1500741 | snp | A | G | missense_variant c.169A>G p.Ser57Gly | tehA | tellurite resistance protein |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1501399 | snp | G | T | missense_variant c.827G>T p.Ser276Ile | tehA | tellurite resistance protein |
| 1501518 | snp | G | A | missense_variant c.946G>A p.Val316Ile | tehA | tellurite resistance protein |
| 1620002 | snp | C | T | missense_variant c.14C>T p.Ser5Leu | marB | multiple antibiotic resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227353 | snp | A | G | missense_variant c.1406T>C p.Leu469Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227510 | snp | C | T | missense_variant c.1249G>A p.Ala417Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227560 | snp | A | G | missense_variant c.1199T>C p.Val400Ala | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227566 | snp | T | C | missense_variant c.1193A>G p.Gln398Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227653 | snp | A | G | missense_variant c.1106T>C p.Ile369Thr | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227872 | snp | G | C | missense_variant c.887C>G p.Pro296Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227935 | snp | T | A | missense_variant c.824A>T p.Asn275Ile | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227949 | snp | A | C | missense_variant c.810T>G p.Ser270Arg | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228109 | snp | C | G | missense_variant c.650G>C p.Arg217Pro | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228239 | snp | G | A | missense_variant c.520C>T p.Arg174Trp | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228265 | snp | G | A | missense_variant c.494C>T p.Pro165Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228349 | snp | G | A | missense_variant c.410C>T p.Ala137Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228367 | snp | C | A | missense_variant c.392G>T p.Arg131Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228397 | snp | G | C | missense_variant c.362C>G p.Ala121Gly | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2228433 | snp | C | A | missense_variant c.326G>T p.Arg109Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2630364 | snp | A | T | missense_variant c.39A>T p.Leu13Phe | yfgI | nalidixic acid resistance protein YfgI |
| 2630599 | snp | T | A | missense_variant c.274T>A p.Ser92Thr | yfgI | nalidixic acid resistance protein YfgI |
| 3635534 | snp | T | A | missense_variant c.694T>A p.Phe232Ile | yhiM | inner membrane protein with a role in acid resistance |
| 3635595 | snp | C | T | missense_variant c.755C>T p.Ala252Val | yhiM | inner membrane protein with a role in acid resistance |
| 3869965 | snp | T | G | missense_variant c.589T>G p.Ser197Ala | cbrA | colicin M resistance protein |
| 3869974 | snp | A | G | missense_variant c.598A>G p.Asn200Asp | cbrA | colicin M resistance protein |
| 3870080 | snp | G | A | missense_variant c.704G>A p.Ser235Asn | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870258 | snp | C | G | missense_variant c.882C>G p.Asp294Glu | cbrA | colicin M resistance protein |
| 3870295 | snp | C | A | missense_variant c.919C>A p.Leu307Ile | cbrA | colicin M resistance protein |
| 4102964 | snp | A | T | missense_variant c.143A>T p.Lys48Met | yiiM | 2-amino-6-N-hydroxylaminopurine resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1500753 | snp | G | A | missense_variant c.181G>A p.Ala61Thr | tehA | tellurite resistance protein |
| 1620120 | snp | C | A | missense_variant c.132C>A p.His44Gln | marB | multiple antibiotic resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227368 | snp | G | A | missense_variant c.1391C>T p.Pro464Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 2227545 | snp | C | A | missense_variant c.1214G>T p.Trp405Leu | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3869407 | snp | C | A | missense_variant c.31C>A p.Leu11Ile | cbrA | colicin M resistance protein |
| 3869698 | snp | A | C | missense_variant c.322A>C p.Lys108Gln | cbrA | colicin M resistance protein |
| 3869713 | snp | G | A | missense_variant c.337G>A p.Ala113Thr | cbrA | colicin M resistance protein |
| 3870106 | snp | A | G | missense_variant c.730A>G p.Thr244Ala | cbrA | colicin M resistance protein |
| 3870253 | snp | A | G | missense_variant c.877A>G p.Thr293Ala | cbrA | colicin M resistance protein |
| 3870268 | snp | T | G | missense_variant c.892T>G p.Ser298Ala | cbrA | colicin M resistance protein |
| 3870412 | snp | G | A | missense_variant c.1036G>A p.Val346Met | cbrA | colicin M resistance protein |
| GenomePosition | Type | ReferenceAllele | AlternateAllele | Consequence | AffectedGene | Product |
|---|---|---|---|---|---|---|
| 5732 | snp | T | G | missense_variant c.728A>C p.Asp243Ala | yaaA | peroxide stress resistance protein YaaA |
| 6162 | snp | C | T | missense_variant c.298G>A p.Asp100Asn | yaaA | peroxide stress resistance protein YaaA |
| 6239 | snp | G | T | missense_variant c.221C>A p.Ala74Glu | yaaA | peroxide stress resistance protein YaaA |
| 1007266 | snp | C | T | missense_variant c.335G>A p.Gly112Glu | ycbX | 6-N-hydroxylaminopurine resistance protein |
| 2227335 | snp | C | A | missense_variant c.1424G>T p.Gly475Val | mdtQ | putative multidrug resistance outer membrane protein MdtQ |
| 3635811 | snp | G | A | missense_variant c.971G>A p.Arg324Gln | yhiM | inner membrane protein with a role in acid resistance |
| Field | Description |
|---|---|
| Contig | Contig name where the gene was found |
| Start | Start position of the gene within the contig |
| End | End position of the gene within the contig |
| Gene | Antibiotic resistance gene |
| Gaps | Gaps in subject (genome) and query (antibiotic resistance gene) |
| Coverage | Proportion (%) of the gene covered |
| Identity | Proportion (%) of exact nucleotide matches |
| Accession | Accesion number of the antibiotic resistance gene |
| Product | Antibiotic resistance gene product |
| Resistance | Antibiotic that the gene confers resistance to |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00021 | 43 | 903 | aac(3)-IIa_1 | 0/0 | 100 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00050 | 1540 | 2139 | aac(6’)-Ib-cr_1 | 0/0 | 100 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00022 | 76948 | 77823 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00050 | 579 | 1409 | blaOXA-1_1 | 0/0 | 100 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00003 | 55500 | 56732 | mdf(A)_1 | 0/0 | 100 | 97.9 | Y08743 | mdf(A) |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00021 | 43 | 903 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00050 | 1540 | 2139 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00009 | 137147 | 140296 | acrB | 0/0 | 100.0 | 98.8 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00014 | 130171 | 133284 | acrD | 0/0 | 100.0 | 98.5 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00016 | 127223 | 128380 | acrE | 0/0 | 100.0 | 98.7 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00016 | 128392 | 131496 | acrF | 0/0 | 100.0 | 96.5 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00016 | 126162 | 126824 | acrS | 0/0 | 100.0 | 98.3 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 83334 | 84155 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00001 | 384476 | 385197 | baeR | 0/0 | 99.9 | 96.7 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00001 | 385194 | 386597 | baeS | 0/0 | 100.0 | 90.6 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00019 | 107883 | 109250 | cpxA | 0/0 | 99.6 | 98.6 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00006 | 15383 | 16015 | CRP | 0/0 | 100.0 | 99.0 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00022 | 76948 | 77823 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00024 | 49360 | 50532 | emrA | 0/0 | 100.0 | 98.1 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00024 | 50549 | 52087 | emrB | 0/0 | 100.0 | 98.1 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00001 | 86333 | 87388 | emrK | 0/0 | 100.0 | 97.3 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00024 | 48703 | 49233 | emrR | 0/0 | 100.0 | 98.5 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00001 | 87388 | 88926 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00010 | 138569 | 140212 | eptA | 0/0 | 100.0 | 91.1 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00009 | 140319 | 141512 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.2 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00015 | 123964 | 125097 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00009 | 47230 | 48387 | Escherichia_coli_ampH | 0/0 | 100.0 | 97.2 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00021 | 62521 | 62853 | Escherichia_coli_emrE | 0/0 | 100.0 | 92.2 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00003 | 55500 | 56732 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.3 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00001 | 85195 | 85809 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00001 | 81597 | 85190 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00006 | 194273 | 195001 | gadW | 0/0 | 100.0 | 99.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00006 | 195370 | 196194 | gadX | 0/0 | 100.0 | 93.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00018 | 22172 | 22585 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00003 | 199372 | 200044 | kdpE | 0/0 | 99.3 | 95.8 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00006 | 225535 | 225918 | marA | 0/0 | 100.0 | 98.2 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 394210 | 395457 | mdtA | 0/0 | 100.0 | 95.8 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00001 | 391088 | 394210 | mdtB | 0/0 | 100.0 | 95.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00001 | 388010 | 391087 | mdtC | 0/0 | 100.0 | 93.9 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00006 | 189615 | 190772 | mdtE | 0/0 | 100.0 | 98.5 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00006 | 190797 | 193910 | mdtF | 0/0 | 100.0 | 97.3 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00007 | 149242 | 150468 | mdtG | 0/0 | 100.0 | 98.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00007 | 159099 | 160307 | mdtH | 0/0 | 100.0 | 98.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00010 | 108311 | 109342 | mdtN | 0/0 | 100.0 | 94.9 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00010 | 106260 | 108311 | mdtO | 0/0 | 100.0 | 97.1 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00010 | 104797 | 106263 | mdtP | 0/0 | 100.0 | 97.7 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00007 | 22609 | 24357 | msbA | 0/0 | 100.0 | 98.1 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00050 | 579 | 1409 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00001 | 187873 | 188841 | pmrF | 0/0 | 100.0 | 97.7 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00008 | 106533 | 108020 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 449838 | 451004 | ugd | 0/0 | 100.0 | 97.0 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00001 | 247373 | 249016 | yojI | 0/0 | 100.0 | 97.9 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00021 | 43 | 903 | (AGly)aac3-IIa | 0/0 | 100 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00015 | 123964 | 125097 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 98.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00009 | 47230 | 48387 | (Bla)ampH_Ecoli | 0/0 | 100 | 97.2 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00022 | 76948 | 77823 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00050 | 579 | 1409 | (Bla)blaOXA-1 | 0/0 | 100 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00003 | 253032 | 254933 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 98.5 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00021 | 43 | 903 | aac(3)-IIe | 0/0 | 100 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00050 | 1540 | 2094 | aac(6’)-Ib-D181Y | 0/0 | 100 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00022 | 76948 | 77823 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00015 | 123964 | 125097 | blaEC-5 | 0/0 | 100 | 99.8 | NG_049085.1 | cephalosporin-hydrolyzing class C beta-lactamase EC-5 | CEPHALOSPORIN |
| contig00050 | 579 | 1409 | blaOXA-1 | 0/0 | 100 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00021 | 43 | 903 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00009 | 140319 | 141512 | ACRA | 0/0 | 100.0 | 99.2 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00009 | 137147 | 140296 | ACRB | 0/0 | 100.0 | 98.8 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00014 | 130171 | 133284 | ACRD | 0/0 | 100.0 | 98.5 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00016 | 127223 | 128380 | ACRE | 0/0 | 100.0 | 98.7 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00016 | 128392 | 131496 | ACRF | 0/0 | 100.0 | 96.5 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00016 | 126162 | 126824 | ACRS | 0/0 | 100.0 | 98.3 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00009 | 47230 | 48387 | AMPH | 0/0 | 100.0 | 97.2 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00001 | 407120 | 408972 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00008 | 83334 | 84155 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00001 | 384476 | 385197 | BAER | 0/0 | 99.9 | 96.7 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00001 | 385194 | 386597 | BAES | 0/0 | 100.0 | 90.6 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 272484 | 273674 | BCR | 0/0 | 100.0 | 96.3 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00015 | 123964 | 125097 | BLAEC | 0/0 | 100.0 | 99.8 | MEG_1275 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00019 | 107188 | 107886 | CPXAR | 0/0 | 100.0 | 97.8 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00019 | 107883 | 109250 | CPXAR | 0/0 | 99.6 | 99.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00006 | 15383 | 16015 | CRP | 0/0 | 100.0 | 99.0 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00024 | 49360 | 50532 | EMRA | 0/0 | 100.0 | 98.1 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00024 | 50549 | 52087 | EMRB | 0/0 | 100.0 | 98.1 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00004 | 212397 | 213587 | EMRD | 0/0 | 100.0 | 97.7 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00001 | 86225 | 87388 | EMRK | 0/0 | 100.0 | 97.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00024 | 48703 | 49233 | EMRR | 0/0 | 100.0 | 98.5 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00001 | 87388 | 88926 | EMRY | 0/0 | 100.0 | 97.8 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00010 | 138569 | 140212 | EPTA | 0/0 | 100.0 | 91.1 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00001 | 81597 | 85190 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00006 | 194273 | 195001 | GADW | 0/0 | 100.0 | 99.7 | MEG_3082 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00006 | 195370 | 196194 | GADX | 0/0 | 100.0 | 93.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00018 | 22172 | 22585 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00003 | 199372 | 200044 | KDPE | 0/0 | 99.3 | 95.8 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00006 | 225529 | 225918 | MARA | 0/0 | 100.0 | 98.2 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00006 | 225080 | 225514 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00003 | 55500 | 56732 | MDFA | 0/0 | 100.0 | 98.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00001 | 394210 | 395457 | MDTA | 0/0 | 100.0 | 95.8 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00001 | 391088 | 394210 | MDTB | 0/0 | 100.0 | 95.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00001 | 388010 | 391087 | MDTC | 0/0 | 100.0 | 93.9 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00006 | 189615 | 190772 | MDTE | 0/0 | 100.0 | 98.5 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00006 | 190797 | 193910 | MDTF | 0/0 | 100.0 | 97.3 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00007 | 149242 | 150468 | MDTG | 0/0 | 100.0 | 98.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00007 | 159099 | 160307 | MDTH | 0/0 | 100.0 | 98.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00005 | 208181 | 208510 | MDTI | 0/0 | 100.0 | 98.8 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00005 | 207829 | 208194 | MDTJ | 0/0 | 100.0 | 97.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00005 | 125894 | 127266 | MDTK | 0/0 | 99.9 | 98.4 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00010 | 108311 | 109342 | MDTN | 0/0 | 100.0 | 94.9 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00010 | 106260 | 108311 | MDTO | 0/0 | 100.0 | 97.1 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00010 | 104797 | 106263 | MDTP | 0/0 | 100.0 | 97.7 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00007 | 22609 | 24357 | MSBA | 0/0 | 100.0 | 98.1 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00021 | 62521 | 62853 | MVRC | 0/0 | 100.0 | 92.2 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00050 | 579 | 1409 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00003 | 253032 | 254933 | PBP2 | 0/0 | 100.0 | 98.5 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00001 | 187873 | 188841 | PMRF | 0/0 | 100.0 | 97.7 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00002 | 234544 | 235413 | ROBA | 0/0 | 100.0 | 97.2 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00010 | 76047 | 76369 | SOXS | 0/0 | 99.7 | 98.1 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00001 | 449838 | 451004 | UGD | 0/0 | 100.0 | 97.0 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00001 | 247373 | 249016 | YOGI | 0/0 | 100.0 | 97.9 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
## [1] "No antibiotic resistance genes from Resfinder database were found"
## [1] "No antibiotic resistance genes from CARD database were found"
## [1] "No antibiotic resistance genes from ARG-ANNOT database were found"
## [1] "No antibiotic resistance genes from NCBI database were found"
## [1] "No antibiotic resistance genes from MEGARES database were found"
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00039 | 21173 | 21706 | ant(2’’)-Ia_1 | 0/0 | 100 | 100.0 | X04555 | ant(2’’)-Ia | Gentamicin, Tobramycin |
| contig00039 | 23573 | 24400 | blaOXA-2_1 | 0/0 | 100 | 100.0 | DQ112222 | blaOXA-2 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Ceftazidime, Piperacillin |
| contig00016 | 41554 | 42414 | blaSHV-18_1 | 0/0 | 100 | 100.0 | AF132290 | blaSHV-18 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00118 | 12802 | 13221 | fosA_6 | 0/0 | 100 | 95.2 | ACZD01000244 | fosA | Fosfomycin |
| contig00002 | 6240 | 7415 | oqxA_1 | 0/0 | 100 | 93.5 | EU370913 | oqxA | Nalidixic_acid, Ciprofloxacin |
| contig00002 | 3064 | 6216 | oqxB_1 | 0/0 | 100 | 95.4 | EU370913 | oqxB | Nalidixic_acid, Ciprofloxacin |
| contig00039 | 24850 | 25716 | sul1_5 | 0/0 | 100 | 99.8 | EU780013 | sul1 | Sulfamethoxazole |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00039 | 21173 | 21706 | ANT(2’’)-Ia | 0/0 | 100.0 | 100.0 | AF078527:3769-4303 | Plasmid or integron-encoded nucleotidylylation of 2-deoxystreptamine aminoglycosides at the hydroxyl group at position 2’’ in P. aeruginosa K. pneumoniae Morganella morganii E. coli S. typhimurium C. freundii and A. baumannii | aminoglycoside |
| contig00118 | 12802 | 13221 | FosA5 | 0/0 | 100.0 | 94.3 | KP143090.1:1619-1199 | fosA5 is a fosfomycin resistance gene isolated from clinical strain of Escherichia coli E265. It is susceptible to amikacin tetracycline and imipenem and resistant to sulphonamide cephalosporins gentamicin ciprofloxacin chloramphenicol and streptomycin | fosfomycin |
| contig00004 | 3141 | 4334 | Klebsiella_pneumoniae_acrA | 2/3 | 99.8 | 95.1 | AJ318073.1:793-1990 | AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae which is encoded by the acrRAB operon. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00246 | 2066 | 2395 | Klebsiella_pneumoniae_KpnF | 0/0 | 100.0 | 93.3 | AP006725.1:2484238-2484568 | KpnF subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime ceftriaxon colistin erythromycin rifampin tetracycline and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate deoxycholate dyes benzalkonium chloride chlorhexidine and triclosan. | aminoglycoside, cephalosporin, macrolide, peptide, rifamycin, tetracycline |
| contig00335 | 550 | 1722 | Klebsiella_pneumoniae_KpnG | 0/0 | 100.0 | 94.6 | ACWO01000051.1:22092-23265 | KpnG consists of ~390 residues and resembles EmrA of E. coli. Disruption of the pump components KpnG-KpnH signficantly decrease resistance to azithromycin ceftazidime ciprofloxacin ertapenem erythromycin gentamicin imipenem ticarcillin norfloxacin polymyxin-B piperacillin spectinomycin tobramycin and streptomycin | aminoglycoside, carbapenem, cephalosporin, fluoroquinolone, macrolide, penam, penem, peptide |
| contig00053 | 1920 | 3044 | Klebsiella_pneumoniae_OmpK37 | 0/0 | 100.0 | 92.5 | AJ011502.1:300-1425 | Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36 which did not allow penetration by certain beta-lactams. Also when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35. | carbapenem, cephalosporin, cephamycin, monobactam, penam, penem |
| contig00002 | 6240 | 7415 | oqxA | 0/0 | 100.0 | 93.5 | EU370913.1:46651-47827 | RND efflux pump conferring resistance to fluoroquinolone | diaminopyrimidine, fluoroquinolone, glycylcycline, nitrofuran, tetracycline |
| contig00002 | 3064 | 6216 | oqxB | 0/0 | 100.0 | 95.4 | EU370913.1:47850-51003 | RND efflux pump conferring resistance to fluoroquinolone | diaminopyrimidine, fluoroquinolone, glycylcycline, nitrofuran, tetracycline |
| contig00039 | 23573 | 24400 | OXA-2 | 0/0 | 100.0 | 100.0 | M95287.4:2455-3283 | OXA-2 is a beta-lactamase found in the Enterobacteriaceae family. | carbapenem, cephalosporin, penam |
| contig00016 | 41554 | 42414 | SHV-18 | 0/0 | 100.0 | 100.0 | AF132290:87-948 | SHV-18 is an extended-spectrum beta-lactamase found in Acinetobacter baumannii and Klebsiella pneumoniae. | carbapenem, cephalosporin, penam |
| contig00039 | 24877 | 25716 | sul1 | 0/0 | 100.0 | 99.9 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00039 | 21173 | 21706 | (AGly)aadB | 0/0 | 100 | 100.0 | JQ690540:4275-4808 | (AGly)aadB | NA |
| contig00039 | 21786 | 22574 | (AGly)aphA16 | 0/0 | 100 | 100.0 | NG_051908:101-889 | (AGly)aphA16 | NA |
| contig00104 | 5274 | 6434 | (Bla)ampH | 0/0 | 100 | 96.0 | CP003785:4208384-4209544 | (Bla)ampH | NA |
| contig00039 | 23573 | 24400 | (Bla)blaOXA-2 | 0/0 | 100 | 100.0 | HM131431:1-828 | (Bla)blaOXA-2 | NA |
| contig00016 | 41554 | 42414 | (Bla)blaSHV-18 | 0/0 | 100 | 100.0 | EU684753:1-861 | (Bla)blaSHV-18 | NA |
| contig00118 | 12802 | 13221 | (Fcyn)FosA5 | 0/0 | 100 | 94.3 | KP143090:1200-1619 | (Fcyn)FosA5 | NA |
| contig00002 | 6240 | 7415 | (Flq)OqxA | 0/0 | 100 | 93.5 | EU370913:46652-47827 | (Flq)OqxA | NA |
| contig00002 | 3064 | 6216 | (Flq)OqxBgb | 0/0 | 100 | 95.4 | EU370913:47851-51003 | (Flq)OqxBgb | NA |
| contig00039 | 24877 | 25716 | (Sul)sul1 | 0/0 | 100 | 99.9 | AF071413:6700-7539 | (Sul)sul1 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00039 | 21173 | 21706 | ant(2’’)-Ia | 0/0 | 100 | 100.0 | NG_047387.1 | aminoglycoside nucleotidyltransferase ANT(2’’)-Ia | GENTAMICIN, KANAMYCIN, TOBRAMYCIN |
| contig00039 | 21786 | 22574 | aphA16 | 0/0 | 100 | 100.0 | NG_051908.1 | APH(3’) family aminoglycoside O-phosphotransferase AphA16 | AMIKACIN, KANAMYCIN |
| contig00039 | 23573 | 24400 | blaOXA-2 | 0/0 | 100 | 100.0 | NG_049496.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-2 | BETA-LACTAM |
| contig00016 | 41554 | 42414 | blaSHV-18 | 0/0 | 100 | 100.0 | NG_050047.1 | class A extended-spectrum beta-lactamase SHV-18 | CEPHALOSPORIN |
| contig00118 | 12802 | 13221 | fosA_gen | 0/0 | 100 | 95.2 | NG_047881.1 | FosA family fosfomycin resistance glutathione transferase | FOSFOMYCIN |
| contig00002 | 6240 | 7415 | oqxA10 | 0/0 | 100 | 93.8 | NG_050418.1 | multidrug efflux RND transporter periplasmic adaptor subunit OqxA10 | PHENICOL, QUINOLONE |
| contig00002 | 3064 | 6216 | oqxB11 | 0/0 | 100 | 95.9 | NG_050429.1 | multidrug efflux RND transporter permease subunit OqxB11 | PHENICOL, QUINOLONE |
| contig00039 | 24877 | 25716 | sul1 | 0/0 | 100 | 100.0 | NG_048081.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00004 | 3141 | 4334 | ACRA | 2/3 | 99.8 | 95.1 | MEG_400 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00104 | 5274 | 6434 | AMPH | 0/0 | 100.0 | 96.0 | MEG_730 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00039 | 21023 | 21706 | ANT2-DPRIME | 1/3 | 100.0 | 99.6 | MEG_757 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT2-DPRIME | NA |
| contig00039 | 21786 | 22574 | APH3-PRIME | 0/0 | 100.0 | 100.0 | MEG_1059 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-PRIME | NA |
| contig00042 | 23627 | 25450 | ASMA | 0/0 | 100.0 | 93.7 | MEG_1179 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00015 | 18768 | 19466 | CPXAR | 0/0 | 100.0 | 97.0 | MEG_2116 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00015 | 19463 | 20836 | CPXAR | 0/0 | 100.0 | 95.8 | MEG_2115 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00036 | 27126 | 28068 | CTX | 0/0 | 100.0 | 95.5 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00137 | 3057 | 3999 | CTX | 0/0 | 100.0 | 95.9 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00118 | 12802 | 13221 | FOSA | 0/0 | 100.0 | 95.2 | MEG_2991 | Drugs:Fosfomycin:Fosfomycin_thiol_transferases:FOSA | NA |
| contig00005 | 53418 | 54649 | KDEA | 0/0 | 99.9 | 94.2 | MEG_3447 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:KDEA | NA |
| contig00335 | 550 | 1722 | KPN | 0/0 | 100.0 | 94.6 | MEG_3512 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:KPN | NA |
| contig00246 | 2066 | 2395 | KPNF | 0/0 | 100.0 | 93.3 | MEG_3515 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:KPNF | NA |
| contig00058 | 18712 | 19803 | KPNO | 2/6 | 99.5 | 95.3 | MEG_3516 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:KPNO | NA |
| contig00053 | 1920 | 3044 | OMP37 | 0/0 | 100.0 | 92.5 | MEG_4283 | Drugs:betalactams:Mutant_porin_proteins:OMP37 | NA |
| contig00002 | 6240 | 7415 | OQXA | 0/0 | 100.0 | 93.8 | MEG_4326 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:OQXA | NA |
| contig00002 | 3064 | 6216 | OQXB | 0/0 | 100.0 | 95.9 | MEG_4364 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:OQXB | NA |
| contig00039 | 23499 | 24625 | OXA | 0/0 | 95.5 | 99.5 | MEG_5208 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00003 | 75561 | 77027 | PHOR | 0/0 | 100.0 | 93.6 | MEG_5786 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_regulator:PHOR | NA |
| contig00039 | 24536 | 24883 | QACEDELTA1 | 0/0 | 100.0 | 100.0 | MEG_5829 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:QACEDELTA1 | NA |
| contig00016 | 41457 | 42460 | SHV | 0/0 | 99.7 | 99.6 | MEG_6428 | Drugs:betalactams:Class_A_betalactamases:SHV | NA |
| contig00039 | 24876 | 25843 | SULI | 0/0 | 100.0 | 99.9 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00195 | 94 | 882 | aadA5_1 | 0/0 | 100.0 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00255 | 8 | 844 | aph(6)-Id_1 | 0/0 | 100.0 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00102 | 8896 | 9771 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00193 | 522 | 1382 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00195 | 1013 | 1486 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00275 | 18 | 591 | dfrA7_5 | 3/4 | 100.0 | 98.8 | AJ419170 | dfrA7 | Trimethoprim |
| contig00039 | 1743 | 2975 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00260 | 67 | 988 | mph(A)_2 | 1/1 | 100.0 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00102 | 3599 | 4255 | qnrS1_1 | 0/0 | 100.0 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| contig00219 | 162 | 1028 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00148 | 1335 | 2581 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00195 | 94 | 882 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00002 | 39532 | 42681 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00017 | 11081 | 14194 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00004 | 121480 | 124584 | acrF | 0/0 | 100.0 | 100.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00004 | 119523 | 120185 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00255 | 8 | 844 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00007 | 54644 | 55465 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00047 | 10640 | 11362 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00047 | 9240 | 10643 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00012 | 61077 | 62450 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00027 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.8 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00102 | 8896 | 9771 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00195 | 1013 | 1486 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00275 | 118 | 591 | dfrA7 | 0/0 | 100.0 | 100.0 | FJ854362:2338-2812 | dfrA7 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00008 | 36546 | 37718 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00045 | 27995 | 29050 | emrK | 0/0 | 100.0 | 99.9 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00008 | 35889 | 36419 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00045 | 26457 | 27995 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00019 | 63251 | 64894 | eptA | 0/0 | 100.0 | 100.0 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00002 | 38316 | 39509 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00076 | 1 | 1129 | Escherichia_coli_ampC | 0/0 | 99.6 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00017 | 45575 | 46879 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 99.9 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00002 | 127675 | 128832 | Escherichia_coli_ampH | 0/0 | 100.0 | 99.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00039 | 1743 | 2975 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00045 | 29574 | 30188 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00045 | 30193 | 33786 | evgS | 0/0 | 100.0 | 99.7 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00041 | 2243 | 2971 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00041 | 1051 | 1875 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00049 | 33308 | 33721 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00095 | 7975 | 8652 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00008 | 37735 | 39273 | Klebsiella_pneumoniae_KpnH | 0/0 | 100.0 | 99.9 | ASTU01000063.1:61248-62787 | KpnH consists of ~511 residues resembles EmrB of E. coli and is probably a translocase in the KpnGH-TolC efflux protein in K. pneumoniae. Disruption of the pump components KpnG-KpnH signficantly decrease resistance to azithromycin ceftazidime ciprofloxacin ertapenem erythromycin gentamicin imipenem ticarcillin norfloxacin polymyxin-B piperacillin spectinomycin tobramycin and streptomycin. | aminoglycoside, carbapenem, cephalosporin, fluoroquinolone, macrolide, penam, penem, peptide |
| contig00034 | 12803 | 13186 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00047 | 347 | 1594 | mdtA | 0/0 | 100.0 | 98.2 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00047 | 1594 | 4716 | mdtB | 0/0 | 100.0 | 97.6 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00047 | 4717 | 7794 | mdtC | 0/0 | 100.0 | 98.2 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00041 | 6472 | 7629 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00041 | 3334 | 6447 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00052 | 18399 | 19625 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00052 | 28254 | 29462 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00070 | 380 | 1591 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00005 | 21785 | 22816 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00005 | 22816 | 24867 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00005 | 24864 | 26330 | mdtP | 0/0 | 100.0 | 99.9 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00260 | 67 | 972 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00030 | 9608 | 10084 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00010 | 21707 | 23455 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00013 | 58318 | 59286 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00102 | 3599 | 4255 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00219 | 162 | 1001 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00193 | 522 | 1382 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00148 | 1335 | 2581 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00007 | 30779 | 32266 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00140 | 141 | 1784 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00195 | 94 | 882 | (AGly)aadA5 | 0/0 | 100.0 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00255 | 8 | 844 | (AGly)strB | 0/0 | 100.0 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00017 | 45575 | 46879 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 99.9 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00076 | 1 | 1129 | (Bla)AmpC2_Ecoli | 0/0 | 99.6 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00002 | 127675 | 128832 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 99.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00102 | 8896 | 9771 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00193 | 522 | 1382 | (Bla)blaTEM-105 | 0/0 | 100.0 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00016 | 45993 | 47894 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00102 | 3599 | 4255 | (Flq)qnr-S1 | 0/0 | 100.0 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| contig00260 | 67 | 972 | (MLS)mph(A) | 0/0 | 100.0 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00219 | 162 | 1001 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00148 | 1307 | 2581 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00148 | 2612 | 3199 | (Tet)tetR | 0/0 | 90.3 | 100.0 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00195 | 1013 | 1486 | (Tmt)dfrA17 | 0/0 | 100.0 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| contig00275 | 118 | 591 | (Tmt)dhfr7 | 0/0 | 100.0 | 100.0 | X58425:594-1067 | (Tmt)dhfr7 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00195 | 94 | 882 | aadA5 | 0/0 | 100.0 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00255 | 8 | 844 | aph(6)-Id | 0/0 | 100.0 | 100.0 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00102 | 8896 | 9771 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00076 | 1 | 1129 | blaEC | 0/0 | 99.6 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00193 | 522 | 1382 | blaTEM-1 | 0/0 | 100.0 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00195 | 1013 | 1486 | dfrA17 | 0/0 | 100.0 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00275 | 118 | 591 | dfrA7 | 0/0 | 100.0 | 100.0 | NG_047737.1 | trimethoprim-resistant dihydrofolate reductase DfrA7 | TRIMETHOPRIM |
| contig00260 | 67 | 988 | mph(A) | 1/1 | 100.0 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00102 | 3599 | 4255 | qnrS1 | 0/0 | 100.0 | 100.0 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| contig00219 | 162 | 1001 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00148 | 1307 | 2506 | tet(A) | 0/0 | 100.0 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00002 | 38316 | 39509 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00002 | 39532 | 42681 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00017 | 11081 | 14194 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00004 | 121480 | 124584 | ACRF | 0/0 | 100.0 | 100.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00004 | 119523 | 120185 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00076 | 1 | 1129 | AMPC | 0/0 | 99.6 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00002 | 127675 | 128832 | AMPH | 0/0 | 100.0 | 99.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00195 | 94 | 882 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00255 | 8 | 844 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00055 | 9351 | 11203 | ASMA | 0/0 | 100.0 | 98.0 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00007 | 54644 | 55465 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00047 | 10640 | 11362 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00047 | 9240 | 10643 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00061 | 2095 | 3285 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00012 | 60382 | 61080 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00012 | 61077 | 62450 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00027 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.8 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00195 | 1013 | 1486 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00275 | 118 | 591 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2548 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00008 | 36546 | 37718 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00014 | 17254 | 18444 | EMRD | 0/0 | 100.0 | 99.9 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00045 | 27995 | 29158 | EMRK | 0/0 | 100.0 | 99.9 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00008 | 35889 | 36419 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00045 | 26457 | 27995 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00019 | 63251 | 64894 | EPTA | 0/0 | 100.0 | 100.0 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00045 | 30193 | 33786 | EVGS | 0/0 | 100.0 | 99.7 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00041 | 2243 | 2971 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00041 | 1051 | 1875 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00049 | 33308 | 33721 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00095 | 7975 | 8652 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00008 | 37735 | 39273 | KPN | 0/0 | 100.0 | 99.9 | MEG_3513 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:KPN | NA |
| contig00034 | 12803 | 13192 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00034 | 13206 | 13640 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00039 | 1743 | 2975 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00047 | 347 | 1594 | MDTA | 0/0 | 100.0 | 98.2 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00047 | 1594 | 4716 | MDTB | 0/0 | 100.0 | 97.6 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00047 | 4717 | 7794 | MDTC | 0/0 | 100.0 | 98.2 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00041 | 6472 | 7629 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00041 | 3334 | 6447 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00052 | 18399 | 19625 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00052 | 28254 | 29462 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00003 | 131924 | 132253 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00003 | 131572 | 131937 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00003 | 60170 | 61543 | MDTK | 0/0 | 100.0 | 100.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00070 | 380 | 1591 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00005 | 21785 | 22816 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00005 | 22816 | 24867 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00005 | 24864 | 26330 | MDTP | 0/0 | 100.0 | 99.9 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00260 | 67 | 988 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00030 | 9608 | 10084 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00010 | 21707 | 23455 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00016 | 45993 | 47894 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00017 | 45575 | 46879 | PBP4B | 0/0 | 100.0 | 99.9 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00013 | 58318 | 59286 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00102 | 3599 | 4255 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00023 | 46359 | 47228 | ROBA | 0/0 | 100.0 | 98.8 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00005 | 48173 | 48495 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00219 | 35 | 1002 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00193 | 504 | 1744 | TEM | 0/0 | 97.9 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00148 | 1307 | 2581 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00140 | 141 | 1784 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00121 | 6460 | 7320 | aac(3)-IId_1 | 0/0 | 100 | 99.9 | EU022314 | aac(3)-IId | Gentamicin, Tobramycin |
| contig00313 | 842 | 1645 | aph(3’’)-Ib_5 | 0/0 | 100 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00313 | 6 | 842 | aph(6)-Id_1 | 0/0 | 100 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00708 | 562 | 1437 | blaCTX-M-27_1 | 0/0 | 100 | 100.0 | AY156923 | blaCTX-M-27 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00134 | 2038 | 2898 | blaTEM-1B_1 | 0/0 | 100 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig01337 | 387 | 860 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00618 | 265 | 1028 | erm(B)_18 | 2/2 | 100 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00134 | 6109 | 7042 | mph(A)_2 | 2/13 | 100 | 98.3 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00313 | 1706 | 2521 | sul2_3 | 0/0 | 100 | 100.0 | HQ840942 | sul2 | Sulfamethoxazole |
| contig00499 | 850 | 2055 | tet(B)_2 | 0/0 | 100 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00121 | 6460 | 7320 | AAC(3)-IId | 0/0 | 100.0 | 99.9 | EU022314.1:0-861 | AAC(3)-IId is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig01076 | 509 | 1171 | acrS | 0/0 | 100.0 | 97.9 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00313 | 842 | 1645 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00313 | 6 | 842 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00626 | 1451 | 2270 | bacA | 0/0 | 99.8 | 97.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00298 | 3362 | 4083 | baeR | 0/0 | 99.9 | 97.4 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00298 | 1962 | 3365 | baeS | 0/0 | 100.0 | 90.1 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00708 | 562 | 1437 | CTX-M-27 | 0/0 | 100.0 | 100.0 | AY156923:0-876 | CTX-M-27 is a beta-lactamase found in Escherichia coli | cephalosporin |
| contig01337 | 387 | 860 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00501 | 943 | 2115 | emrA | 0/0 | 100.0 | 97.8 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00013 | 19083 | 20138 | emrK | 0/0 | 100.0 | 96.9 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00501 | 286 | 816 | emrR | 0/0 | 100.0 | 99.2 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00013 | 17545 | 19083 | emrY | 0/0 | 100.0 | 98.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00618 | 291 | 1036 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00041 | 8903 | 10207 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 95.4 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00402 | 89 | 3663 | evgS | 0/0 | 99.5 | 96.3 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig01206 | 403 | 1131 | gadW | 0/0 | 100.0 | 96.8 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig01290 | 366 | 1132 | gadX | 0/0 | 93.0 | 93.7 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig01085 | 753 | 1166 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00077 | 7214 | 7891 | kdpE | 0/0 | 100.0 | 96.6 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00075 | 249 | 632 | marA | 0/0 | 100.0 | 99.7 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00090 | 8496 | 9743 | mdtA | 0/0 | 100.0 | 95.6 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00273 | 268 | 1494 | mdtG | 0/0 | 100.0 | 98.0 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00236 | 3719 | 4927 | mdtH | 0/0 | 100.0 | 97.9 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00176 | 2303 | 3535 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00352 | 3072 | 4015 | mdtN | 0/0 | 91.5 | 97.8 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00563 | 645 | 2111 | mdtP | 0/0 | 100.0 | 96.5 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00134 | 6125 | 7042 | mphA | 1/12 | 100.0 | 98.6 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00145 | 2809 | 3285 | mphB | 0/0 | 100.0 | 98.1 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00313 | 1706 | 2521 | sul2 | 0/0 | 100.0 | 99.6 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00134 | 2038 | 2898 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00499 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00181 | 3394 | 4560 | ugd | 0/0 | 100.0 | 97.3 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00121 | 6460 | 7320 | (AGly)aac3-IId | 0/0 | 100 | 99.9 | EU022314:1-861 | (AGly)aac3-IId | NA |
| contig00313 | 842 | 1645 | (AGly)strA | 0/0 | 100 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00313 | 6 | 842 | (AGly)strB | 0/0 | 100 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00041 | 8903 | 10207 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 95.4 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00708 | 562 | 1437 | (Bla)blaCTX-M-27 | 0/0 | 100 | 100.0 | AY156923:1-876 | (Bla)blaCTX-M-27 | NA |
| contig00134 | 2038 | 2898 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00618 | 291 | 1028 | (MLS)erm(B) | 0/0 | 100 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00134 | 6125 | 7042 | (MLS)mph(A) | 1/12 | 100 | 98.6 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00313 | 1706 | 2521 | (Sul)sul2 | 0/0 | 100 | 99.6 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00499 | 850 | 2055 | (Tet)tetB | 0/0 | 100 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig01337 | 387 | 860 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00121 | 6460 | 7320 | aac(3)-IId | 0/0 | 100 | 100.0 | NG_047251.1 | aminoglycoside N-acetyltransferase AAC(3)-IId | GENTAMICIN |
| contig00313 | 842 | 1669 | aph(3’’)-Ib | 0/0 | 100 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00313 | 6 | 842 | aph(6)-Id | 0/0 | 100 | 100.0 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00708 | 562 | 1437 | blaCTX-M-27 | 0/0 | 100 | 100.0 | NG_048976.1 | class A extended-spectrum beta-lactamase CTX-M-27 | CEPHALOSPORIN |
| contig00134 | 2038 | 2898 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig01337 | 387 | 860 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00618 | 291 | 1028 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00134 | 6109 | 7042 | mph(A) | 2/13 | 100 | 98.3 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00313 | 1706 | 2521 | sul2 | 0/0 | 100 | 99.9 | NG_048118.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00499 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00121 | 6460 | 7320 | AAC3 | 0/0 | 100.0 | 100.0 | MEG_64 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig01076 | 509 | 1171 | ACRS | 0/0 | 100.0 | 97.9 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00313 | 842 | 1669 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00313 | 6 | 842 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00426 | 1170 | 3023 | ASMA | 0/0 | 100.0 | 98.0 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00626 | 1451 | 2270 | BACA | 0/0 | 99.8 | 97.2 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00298 | 3362 | 4083 | BAER | 0/0 | 99.9 | 97.4 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00298 | 1962 | 3365 | BAES | 0/0 | 100.0 | 90.1 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig01054 | 82 | 1272 | BCR | 0/0 | 100.0 | 96.7 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00708 | 540 | 1443 | CTX | 0/0 | 100.0 | 99.8 | MEG_2401 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig01337 | 387 | 860 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00501 | 943 | 2115 | EMRA | 0/0 | 100.0 | 97.8 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00013 | 19083 | 20246 | EMRK | 0/0 | 100.0 | 96.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00501 | 286 | 816 | EMRR | 0/0 | 100.0 | 99.2 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00013 | 17545 | 19083 | EMRY | 0/0 | 100.0 | 98.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00618 | 265 | 1028 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00402 | 89 | 3663 | EVGS | 0/0 | 99.5 | 97.4 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig01206 | 403 | 1131 | GADW | 0/0 | 100.0 | 97.1 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig01290 | 366 | 1132 | GADX | 0/0 | 93.0 | 93.7 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig01085 | 753 | 1166 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00077 | 7214 | 7891 | KDPE | 0/0 | 100.0 | 96.6 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00075 | 243 | 632 | MARA | 0/0 | 100.0 | 99.7 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00090 | 8496 | 9743 | MDTA | 0/0 | 100.0 | 95.6 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00273 | 268 | 1494 | MDTG | 0/0 | 100.0 | 98.3 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00236 | 3719 | 4927 | MDTH | 0/0 | 100.0 | 97.9 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00449 | 148 | 513 | MDTJ | 0/0 | 100.0 | 98.6 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00176 | 2303 | 3535 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00352 | 3072 | 4015 | MDTN | 0/0 | 91.5 | 97.8 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00563 | 645 | 2111 | MDTP | 0/0 | 100.0 | 96.5 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00134 | 6109 | 7042 | MPHA | 2/13 | 100.0 | 98.3 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00145 | 2809 | 3285 | MPHB | 0/0 | 100.0 | 98.1 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00041 | 8903 | 10207 | PBP4B | 0/0 | 100.0 | 95.4 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00360 | 1212 | 2081 | ROBA | 0/0 | 100.0 | 99.1 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00567 | 451 | 773 | SOXS | 0/0 | 99.7 | 97.5 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00313 | 1706 | 2521 | SULII | 0/0 | 100.0 | 100.0 | MEG_6618 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00499 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00181 | 3394 | 4560 | UGD | 0/0 | 100.0 | 97.3 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig02215 | 28 | 888 | aac(3)-IIa_1 | 0/0 | 100.0 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig01588 | 744 | 1343 | aac(6’)-Ib-cr_1 | 0/0 | 100.0 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00690 | 1345 | 2133 | aadA5_1 | 0/0 | 100.0 | 99.9 | AF137361 | aadA5 | Streptomycin |
| contig00217 | 567 | 1370 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00620 | 1685 | 2560 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00063 | 5098 | 5958 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00614 | 183 | 665 | dfrA14_5 | 0/0 | 100.0 | 99.6 | DQ388123 | dfrA14 | Trimethoprim |
| contig00690 | 2264 | 2737 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00063 | 357 | 1278 | mph(A)_2 | 1/1 | 100.0 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00690 | 1 | 825 | sul1_5 | 0/0 | 95.2 | 99.8 | EU780013 | sul1 | Sulfamethoxazole |
| contig00217 | 1431 | 2246 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig01353 | 144 | 1390 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| contig00212 | 1997 | 3202 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig02215 | 28 | 888 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig01588 | 744 | 1343 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00690 | 1345 | 2133 | aadA5 | 0/0 | 100.0 | 99.9 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00872 | 1299 | 1961 | acrS | 0/0 | 100.0 | 99.1 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00217 | 567 | 1370 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00546 | 1993 | 2814 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00040 | 66 | 1469 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig01125 | 280 | 1683 | baeS | 0/0 | 100.0 | 90.5 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00590 | 14 | 1387 | cpxA | 0/0 | 100.0 | 98.3 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00620 | 1685 | 2560 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00614 | 183 | 665 | dfrA14 | 0/0 | 100.0 | 99.8 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00690 | 2264 | 2737 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00901 | 1043 | 2215 | emrA | 0/0 | 100.0 | 99.3 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00901 | 386 | 916 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00306 | 281 | 1819 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00798 | 1 | 1604 | eptA | 0/0 | 97.6 | 99.3 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00960 | 1 | 1604 | eptA | 0/0 | 97.6 | 91.3 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00567 | 944 | 2077 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.4 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00140 | 5012 | 6316 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.6 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00137 | 5343 | 6500 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00983 | 618 | 950 | Escherichia_coli_emrE | 0/0 | 100.0 | 92.2 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig01875 | 533 | 1147 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00476 | 1 | 3514 | evgS | 0/0 | 97.8 | 100.0 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig01144 | 177 | 905 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig01154 | 178 | 906 | gadW | 0/0 | 100.0 | 100.0 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig01410 | 783 | 1563 | gadX | 0/0 | 94.7 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig01957 | 363 | 1143 | gadX | 0/0 | 94.7 | 93.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00136 | 3266 | 3943 | kdpE | 0/0 | 100.0 | 99.8 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00040 | 9082 | 10329 | mdtA | 0/0 | 100.0 | 100.0 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig01993 | 1 | 1126 | mdtA | 0/0 | 90.2 | 95.4 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00040 | 5960 | 9082 | mdtB | 0/0 | 100.0 | 98.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00040 | 2882 | 5959 | mdtC | 0/0 | 100.0 | 99.9 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00979 | 1 | 1133 | mdtG | 1/1 | 92.3 | 99.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00373 | 234 | 1442 | mdtH | 0/0 | 100.0 | 97.8 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00324 | 263 | 1474 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00060 | 4283 | 5314 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig01887 | 1 | 973 | mdtN | 0/0 | 94.3 | 96.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00060 | 5314 | 7365 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00060 | 7362 | 8828 | mdtP | 0/0 | 100.0 | 99.9 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00063 | 373 | 1278 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00020 | 3085 | 3561 | mphB | 0/0 | 100.0 | 98.1 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00082 | 3188 | 4936 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00690 | 1 | 798 | sul1 | 0/0 | 95.0 | 99.9 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00217 | 1431 | 2246 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00063 | 5098 | 5958 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig01353 | 144 | 1390 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00212 | 1997 | 3202 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00680 | 587 | 1753 | ugd | 0/0 | 100.0 | 96.0 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig02215 | 28 | 888 | (AGly)aac3-IIa | 0/0 | 100 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00690 | 1345 | 2133 | (AGly)aadA5 | 0/0 | 100 | 99.9 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00217 | 567 | 1370 | (AGly)strA | 0/0 | 100 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00140 | 5012 | 6316 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 98.6 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00567 | 944 | 2077 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 98.4 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00137 | 5343 | 6500 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00620 | 1685 | 2560 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00063 | 5098 | 5958 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00063 | 373 | 1278 | (MLS)mph(A) | 0/0 | 100 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00690 | 1 | 798 | (Sul)sul1 | 0/0 | 95 | 99.9 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00217 | 1431 | 2246 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig01353 | 116 | 1390 | (Tet)tetA | 0/0 | 100 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00212 | 1997 | 3202 | (Tet)tetB | 0/0 | 100 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00614 | 183 | 656 | (Tmt)dfrA14 | 0/0 | 100 | 100.0 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| contig00690 | 2264 | 2737 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig02215 | 28 | 888 | aac(3)-IIe | 0/0 | 100.0 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig01588 | 744 | 1298 | aac(6’)-Ib-D181Y | 0/0 | 100.0 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00690 | 1345 | 2133 | aadA5 | 0/0 | 100.0 | 99.9 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00217 | 567 | 1394 | aph(3’’)-Ib | 0/0 | 100.0 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00620 | 1685 | 2560 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00567 | 944 | 2077 | blaEC | 0/0 | 100.0 | 99.9 | NG_047496.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00063 | 5098 | 5958 | blaTEM-1 | 0/0 | 100.0 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00614 | 183 | 656 | dfrA14 | 0/0 | 100.0 | 100.0 | NG_056035.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| contig00690 | 2264 | 2737 | dfrA17 | 0/0 | 100.0 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00063 | 357 | 1278 | mph(A) | 1/1 | 100.0 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00690 | 1 | 798 | sul1 | 0/0 | 96.4 | 99.9 | NG_048089.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00217 | 1431 | 2246 | sul2 | 0/0 | 100.0 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig01353 | 116 | 1315 | tet(A) | 0/0 | 100.0 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| contig00212 | 1997 | 3202 | tet(B) | 0/0 | 100.0 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig02215 | 28 | 888 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00872 | 1299 | 1961 | ACRS | 0/0 | 100.0 | 99.1 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00137 | 5343 | 6500 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00690 | 1345 | 2133 | ANT3-DPRIME | 0/0 | 100.0 | 99.9 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00217 | 567 | 1394 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00546 | 1993 | 2814 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00040 | 66 | 1469 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig01125 | 280 | 1683 | BAES | 0/0 | 100.0 | 90.5 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00567 | 944 | 2077 | BLAEC | 0/0 | 100.0 | 99.9 | MEG_1276 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00590 | 14 | 1387 | CPXAR | 0/0 | 100.0 | 98.8 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00614 | 183 | 656 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00690 | 2264 | 2737 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00901 | 1043 | 2215 | EMRA | 0/0 | 100.0 | 99.3 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00901 | 386 | 916 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00306 | 281 | 1819 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00798 | 1 | 1604 | EPTA | 0/0 | 97.6 | 99.3 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00960 | 1 | 1604 | EPTA | 0/0 | 97.6 | 91.3 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00476 | 1 | 3514 | EVGS | 0/0 | 97.8 | 100.0 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig01144 | 177 | 905 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig01154 | 178 | 906 | GADW | 0/0 | 100.0 | 100.0 | MEG_3082 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig01410 | 783 | 1563 | GADX | 0/0 | 94.7 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig01957 | 363 | 1143 | GADX | 0/0 | 94.7 | 93.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00136 | 3266 | 3943 | KDPE | 0/0 | 100.0 | 99.8 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig01038 | 1256 | 1690 | MARR | 0/0 | 100.0 | 97.5 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig02349 | 256 | 690 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00040 | 9082 | 10329 | MDTA | 0/0 | 100.0 | 100.0 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig01993 | 1 | 1126 | MDTA | 0/0 | 90.2 | 95.4 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00040 | 5960 | 9082 | MDTB | 0/0 | 100.0 | 98.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00040 | 2882 | 5959 | MDTC | 0/0 | 100.0 | 99.9 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00979 | 1 | 1133 | MDTG | 1/1 | 92.3 | 99.8 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00373 | 234 | 1442 | MDTH | 0/0 | 100.0 | 97.8 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig01531 | 65 | 394 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig02284 | 674 | 979 | MDTI | 0/0 | 92.7 | 99.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00796 | 1232 | 2488 | MDTK | 0/0 | 91.5 | 98.9 | MEG_3758 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00324 | 263 | 1474 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00060 | 4283 | 5314 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig01887 | 1 | 973 | MDTN | 0/0 | 94.3 | 96.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00060 | 5314 | 7365 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00060 | 7362 | 8828 | MDTP | 0/0 | 100.0 | 99.9 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00063 | 357 | 1278 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00020 | 3085 | 3561 | MPHB | 0/0 | 100.0 | 98.1 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00082 | 3188 | 4936 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00983 | 618 | 950 | MVRC | 0/0 | 100.0 | 92.2 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00140 | 5012 | 6316 | PBP4B | 0/0 | 100.0 | 98.6 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00958 | 459 | 1328 | ROBA | 0/0 | 100.0 | 98.8 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00221 | 2037 | 2359 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00690 | 1 | 885 | SULI | 0/0 | 95.5 | 99.9 | MEG_6616 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00217 | 1431 | 2246 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00063 | 5080 | 6325 | TEM | 0/0 | 98.3 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig01353 | 116 | 1390 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00212 | 1997 | 3202 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00212 | 3996 | 4412 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00680 | 587 | 1753 | UGD | 0/0 | 100.0 | 96.0 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00077 | 901 | 1702 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00024 | 79762 | 80637 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00076 | 5984 | 6643 | catA1_1 | 0/0 | 100.0 | 99.8 | V00622 | catA1 | Chloramphenicol |
| contig00077 | 6 | 503 | dfrA12_8 | 0/0 | 100.0 | 99.8 | AM040708 | dfrA12 | Trimethoprim |
| contig00084 | 2247 | 3010 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00001 | 25629 | 26861 | mdf(A)_1 | 0/0 | 100.0 | 98.5 | Y08743 | mdf(A) | |
| contig00084 | 161 | 1091 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00077 | 2180 | 3046 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00086 | 800 | 2005 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00077 | 923 | 1702 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00010 | 89029 | 92178 | acrB | 0/0 | 100.0 | 99.1 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 101962 | 105075 | acrD | 0/0 | 100.0 | 98.9 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00003 | 223403 | 224560 | acrE | 0/0 | 100.0 | 98.8 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00003 | 224572 | 227676 | acrF | 0/0 | 100.0 | 99.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00003 | 222342 | 223004 | acrS | 0/0 | 100.0 | 99.4 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 13409 | 14228 | bacA | 0/0 | 99.8 | 98.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00018 | 65847 | 66569 | baeR | 0/0 | 100.0 | 99.3 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00018 | 64447 | 65850 | baeS | 0/0 | 100.0 | 99.6 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00076 | 5984 | 6643 | catI | 0/0 | 100.0 | 99.8 | V00622:243-903 | catI is a chromosome and transposon-encoded variant of the cat gene found in Escherichia coli and Acinetobacter baumannii | phenicol |
| contig00029 | 22407 | 23780 | cpxA | 0/0 | 100.0 | 98.8 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00005 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00024 | 79762 | 80637 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00077 | 6 | 503 | dfrA12 | 0/0 | 100.0 | 99.8 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00066 | 5291 | 6463 | emrA | 0/0 | 100.0 | 98.2 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00066 | 3736 | 5274 | emrB | 0/0 | 100.0 | 99.9 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00002 | 10208 | 11263 | emrK | 0/0 | 100.0 | 99.2 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00066 | 6590 | 7120 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00002 | 8670 | 10208 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00031 | 18311 | 19954 | eptA | 0/0 | 100.0 | 99.4 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00084 | 2273 | 3018 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00010 | 92201 | 93394 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.8 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00032 | 48509 | 49642 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.5 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00002 | 69540 | 70844 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00010 | 683 | 1840 | Escherichia_coli_ampH | 0/0 | 100.0 | 99.2 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00001 | 25629 | 26861 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.9 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00002 | 11787 | 12401 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00002 | 12406 | 15999 | evgS | 0/0 | 100.0 | 99.6 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00042 | 31471 | 32199 | gadW | 0/0 | 100.0 | 94.4 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00042 | 32567 | 33391 | gadX | 0/0 | 100.0 | 97.9 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00004 | 173845 | 174258 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00012 | 7933 | 8605 | kdpE | 0/0 | 99.3 | 97.2 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00030 | 40685 | 41068 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00018 | 55587 | 56834 | mdtA | 0/0 | 100.0 | 98.2 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00018 | 56834 | 59956 | mdtB | 0/0 | 100.0 | 98.0 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00018 | 59957 | 63034 | mdtC | 0/0 | 100.0 | 98.1 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00042 | 26813 | 27970 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00042 | 27995 | 31108 | mdtF | 0/0 | 100.0 | 98.5 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00025 | 38609 | 39835 | mdtG | 0/0 | 100.0 | 99.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00025 | 28770 | 29978 | mdtH | 0/0 | 100.0 | 98.5 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00053 | 356 | 1588 | mdtM | 0/0 | 100.0 | 96.8 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00016 | 10888 | 11919 | mdtN | 0/0 | 100.0 | 98.1 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00016 | 11919 | 13970 | mdtO | 0/0 | 100.0 | 98.3 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00016 | 13967 | 15433 | mdtP | 0/0 | 100.0 | 98.2 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00084 | 189 | 1091 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00002 | 126351 | 126825 | mphB | 0/0 | 99.6 | 97.5 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00001 | 152597 | 154345 | msbA | 0/0 | 100.0 | 99.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00007 | 32303 | 33271 | pmrF | 0/0 | 100.0 | 99.5 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00077 | 2207 | 3046 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00086 | 800 | 2005 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00036 | 36177 | 37664 | tolC | 0/0 | 100.0 | 98.4 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00019 | 14595 | 16238 | yojI | 0/0 | 100.0 | 98.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00077 | 923 | 1702 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00002 | 69540 | 70844 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 98.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00032 | 48509 | 49642 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 97.5 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00010 | 683 | 1840 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 99.2 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00024 | 79762 | 80637 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00012 | 60394 | 62295 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 99.4 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00084 | 2273 | 3010 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00084 | 189 | 1091 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00076 | 5984 | 6643 | (Phe)catA1 | 0/0 | 100.0 | 99.8 | V00622:244-903 | (Phe)catA1 | NA |
| contig00077 | 2207 | 3046 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00086 | 800 | 2005 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00077 | 6 | 503 | (Tmt)dfrA12 | 0/0 | 100.0 | 99.8 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00077 | 911 | 1702 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00024 | 79762 | 80637 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00032 | 48509 | 49642 | blaEC-13 | 0/0 | 100 | 99.9 | NG_049079.1 | class C extended-spectrum beta-lactamase EC-13 | CEPHALOSPORIN |
| contig00076 | 5984 | 6643 | catA1 | 0/0 | 100 | 99.8 | NG_047582.1 | type A-1 chloramphenicol O-acetyltransferase | CHLORAMPHENICOL |
| contig00077 | 6 | 503 | dfrA12 | 0/0 | 100 | 99.8 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00084 | 2273 | 3010 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00084 | 161 | 1091 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00077 | 2207 | 3046 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00086 | 800 | 2005 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00010 | 92201 | 93394 | ACRA | 0/0 | 100.0 | 99.8 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00010 | 89029 | 92178 | ACRB | 0/0 | 100.0 | 99.1 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00002 | 101962 | 105075 | ACRD | 0/0 | 100.0 | 98.9 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00003 | 223403 | 224560 | ACRE | 0/0 | 100.0 | 98.8 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00003 | 224572 | 227676 | ACRF | 0/0 | 100.0 | 99.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00003 | 222342 | 223004 | ACRS | 0/0 | 100.0 | 99.4 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00010 | 683 | 1840 | AMPH | 0/0 | 100.0 | 99.2 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00077 | 901 | 1702 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00018 | 41800 | 43652 | ASMA | 0/0 | 100.0 | 98.4 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00003 | 13409 | 14228 | BACA | 0/0 | 99.8 | 98.9 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00018 | 65847 | 66569 | BAER | 0/0 | 100.0 | 99.3 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00018 | 64447 | 65850 | BAES | 0/0 | 100.0 | 99.6 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00019 | 41510 | 42700 | BCR | 0/0 | 100.0 | 98.2 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00032 | 48509 | 49642 | BLAEC | 0/0 | 100.0 | 99.9 | MEG_1280 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00076 | 5984 | 6648 | CATA | 0/0 | 99.1 | 100.0 | MEG_1593 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00029 | 21712 | 22410 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00029 | 22407 | 23780 | CPXAR | 0/0 | 100.0 | 99.5 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00005 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00018 | 92803 | 93691 | CTX | 0/0 | 100.0 | 97.4 | MEG_2430 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00077 | 6 | 503 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00066 | 5291 | 6463 | EMRA | 0/0 | 100.0 | 98.2 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00066 | 3736 | 5274 | EMRB | 0/0 | 100.0 | 99.9 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00014 | 22228 | 23418 | EMRD | 0/0 | 100.0 | 99.8 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00002 | 10208 | 11371 | EMRK | 0/0 | 100.0 | 99.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00066 | 6590 | 7120 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00002 | 8670 | 10208 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00031 | 18311 | 19954 | EPTA | 0/0 | 100.0 | 99.4 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00084 | 2247 | 3010 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00002 | 12406 | 15999 | EVGS | 0/0 | 100.0 | 99.6 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00042 | 31471 | 32199 | GADW | 0/0 | 100.0 | 98.6 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00042 | 32567 | 33391 | GADX | 0/0 | 100.0 | 97.9 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00004 | 173845 | 174258 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00012 | 7933 | 8605 | KDPE | 0/0 | 99.3 | 97.2 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00030 | 40679 | 41068 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00030 | 40231 | 40665 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00001 | 25629 | 26861 | MDFA | 0/0 | 100.0 | 98.5 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00018 | 55587 | 56834 | MDTA | 0/0 | 100.0 | 98.2 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00018 | 56834 | 59956 | MDTB | 0/0 | 100.0 | 98.0 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00018 | 59957 | 63034 | MDTC | 0/0 | 100.0 | 98.1 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00042 | 26813 | 27970 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00042 | 27995 | 31108 | MDTF | 0/0 | 100.0 | 98.5 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00025 | 38609 | 39835 | MDTG | 0/0 | 100.0 | 99.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00025 | 28770 | 29978 | MDTH | 0/0 | 100.0 | 98.5 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00021 | 35394 | 35723 | MDTI | 0/0 | 100.0 | 99.1 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00021 | 35042 | 35407 | MDTJ | 0/0 | 100.0 | 99.7 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00017 | 65582 | 66955 | MDTK | 0/0 | 100.0 | 99.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00053 | 356 | 1588 | MDTM | 0/0 | 100.0 | 96.8 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00016 | 10888 | 11919 | MDTN | 0/0 | 100.0 | 98.1 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00016 | 11919 | 13970 | MDTO | 0/0 | 100.0 | 98.3 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00016 | 13967 | 15433 | MDTP | 0/0 | 100.0 | 98.2 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00084 | 161 | 1091 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00002 | 126351 | 126825 | MPHB | 0/0 | 99.6 | 97.5 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00001 | 152597 | 154345 | MSBA | 0/0 | 100.0 | 99.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00012 | 60394 | 62295 | PBP2 | 0/0 | 100.0 | 99.4 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00002 | 69540 | 70844 | PBP4B | 0/0 | 100.0 | 98.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00007 | 32303 | 33271 | PMRF | 0/0 | 100.0 | 99.5 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00027 | 11922 | 12791 | ROBA | 0/0 | 100.0 | 99.1 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00016 | 37049 | 37372 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00077 | 2206 | 3173 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00086 | 800 | 2005 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00086 | 2799 | 3215 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00019 | 14595 | 16238 | YOGI | 0/0 | 100.0 | 98.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00085 | 901 | 1702 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00006 | 2052 | 2927 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00087 | 1420 | 2079 | catA1_1 | 0/0 | 100.0 | 99.8 | V00622 | catA1 | Chloramphenicol |
| contig00085 | 6 | 503 | dfrA12_8 | 0/0 | 100.0 | 99.8 | AM040708 | dfrA12 | Trimethoprim |
| contig00096 | 2354 | 3117 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00037 | 18321 | 19553 | mdf(A)_1 | 0/0 | 100.0 | 98.5 | Y08743 | mdf(A) | |
| contig00096 | 268 | 1198 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00085 | 2180 | 3046 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00098 | 800 | 2005 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00085 | 923 | 1702 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00014 | 89029 | 92178 | acrB | 0/0 | 100.0 | 99.1 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 123264 | 126377 | acrD | 0/0 | 100.0 | 98.9 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00002 | 223403 | 224560 | acrE | 0/0 | 100.0 | 98.8 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00002 | 224572 | 227676 | acrF | 0/0 | 100.0 | 99.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00002 | 222342 | 223004 | acrS | 0/0 | 100.0 | 99.4 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 13409 | 14228 | bacA | 0/0 | 99.8 | 98.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00013 | 65847 | 66569 | baeR | 0/0 | 100.0 | 99.3 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00013 | 64447 | 65850 | baeS | 0/0 | 100.0 | 99.6 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00087 | 1420 | 2079 | catI | 0/0 | 100.0 | 99.8 | V00622:243-903 | catI is a chromosome and transposon-encoded variant of the cat gene found in Escherichia coli and Acinetobacter baumannii | phenicol |
| contig00056 | 22407 | 23780 | cpxA | 0/0 | 100.0 | 98.8 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00007 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00006 | 2052 | 2927 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00085 | 6 | 503 | dfrA12 | 0/0 | 100.0 | 99.8 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00055 | 5175 | 6347 | emrA | 0/0 | 100.0 | 98.2 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00055 | 3620 | 5158 | emrB | 0/0 | 100.0 | 99.9 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00001 | 31510 | 32565 | emrK | 0/0 | 100.0 | 99.2 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00055 | 6474 | 7004 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00001 | 29972 | 31510 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00030 | 18346 | 19989 | eptA | 0/0 | 100.0 | 99.4 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00096 | 2380 | 3125 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00014 | 92201 | 93394 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.8 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00031 | 49645 | 50778 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.5 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00001 | 90842 | 92146 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00014 | 683 | 1840 | Escherichia_coli_ampH | 0/0 | 100.0 | 99.2 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00037 | 18321 | 19553 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.9 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00001 | 33089 | 33703 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00001 | 33708 | 37301 | evgS | 0/0 | 100.0 | 99.6 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00020 | 31471 | 32199 | gadW | 0/0 | 100.0 | 94.4 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00020 | 32567 | 33391 | gadX | 0/0 | 100.0 | 97.9 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00018 | 10093 | 10506 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00045 | 8520 | 9192 | kdpE | 0/0 | 99.3 | 97.2 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00028 | 40685 | 41068 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00013 | 55587 | 56834 | mdtA | 0/0 | 100.0 | 98.2 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00013 | 56834 | 59956 | mdtB | 0/0 | 100.0 | 98.0 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00013 | 59957 | 63034 | mdtC | 0/0 | 100.0 | 98.1 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00020 | 26813 | 27970 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00020 | 27995 | 31108 | mdtF | 0/0 | 100.0 | 98.5 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00006 | 121340 | 122566 | mdtG | 0/0 | 100.0 | 99.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00006 | 111501 | 112709 | mdtH | 0/0 | 100.0 | 98.5 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00019 | 52386 | 53618 | mdtM | 0/0 | 100.0 | 96.8 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00010 | 10863 | 11894 | mdtN | 0/0 | 100.0 | 98.1 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00010 | 11894 | 13945 | mdtO | 0/0 | 100.0 | 98.3 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00010 | 13942 | 15408 | mdtP | 0/0 | 100.0 | 98.2 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00096 | 296 | 1198 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00001 | 147653 | 148127 | mphB | 0/0 | 99.6 | 97.5 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00003 | 31022 | 32770 | msbA | 0/0 | 100.0 | 99.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00011 | 16717 | 17685 | pmrF | 0/0 | 100.0 | 99.5 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00085 | 2207 | 3046 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00098 | 800 | 2005 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00035 | 36177 | 37664 | tolC | 0/0 | 100.0 | 98.4 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00032 | 30181 | 31824 | yojI | 0/0 | 100.0 | 98.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00085 | 923 | 1702 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00001 | 90842 | 92146 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 98.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00031 | 49645 | 50778 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 97.5 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00014 | 683 | 1840 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 99.2 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00006 | 2052 | 2927 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00046 | 13699 | 15600 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 99.4 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00096 | 2380 | 3117 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00096 | 296 | 1198 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00087 | 1420 | 2079 | (Phe)catA1 | 0/0 | 100.0 | 99.8 | V00622:244-903 | (Phe)catA1 | NA |
| contig00085 | 2207 | 3046 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00098 | 800 | 2005 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00085 | 6 | 503 | (Tmt)dfrA12 | 0/0 | 100.0 | 99.8 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00085 | 911 | 1702 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00006 | 2052 | 2927 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00031 | 49645 | 50778 | blaEC-13 | 0/0 | 100 | 99.9 | NG_049079.1 | class C extended-spectrum beta-lactamase EC-13 | CEPHALOSPORIN |
| contig00087 | 1420 | 2079 | catA1 | 0/0 | 100 | 99.8 | NG_047582.1 | type A-1 chloramphenicol O-acetyltransferase | CHLORAMPHENICOL |
| contig00085 | 6 | 503 | dfrA12 | 0/0 | 100 | 99.8 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00096 | 2380 | 3117 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00096 | 268 | 1198 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00085 | 2207 | 3046 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00098 | 800 | 2005 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00014 | 92201 | 93394 | ACRA | 0/0 | 100.0 | 99.8 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00014 | 89029 | 92178 | ACRB | 0/0 | 100.0 | 99.1 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00001 | 123264 | 126377 | ACRD | 0/0 | 100.0 | 98.9 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00002 | 223403 | 224560 | ACRE | 0/0 | 100.0 | 98.8 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00002 | 224572 | 227676 | ACRF | 0/0 | 100.0 | 99.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00002 | 222342 | 223004 | ACRS | 0/0 | 100.0 | 99.4 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00014 | 683 | 1840 | AMPH | 0/0 | 100.0 | 99.2 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00085 | 901 | 1702 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00013 | 41800 | 43652 | ASMA | 0/0 | 100.0 | 98.4 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00002 | 13409 | 14228 | BACA | 0/0 | 99.8 | 98.9 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00013 | 65847 | 66569 | BAER | 0/0 | 100.0 | 99.3 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00013 | 64447 | 65850 | BAES | 0/0 | 100.0 | 99.6 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00017 | 83075 | 84265 | BCR | 0/0 | 100.0 | 98.2 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00031 | 49645 | 50778 | BLAEC | 0/0 | 100.0 | 99.9 | MEG_1280 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00087 | 1415 | 2079 | CATA | 0/0 | 99.1 | 100.0 | MEG_1593 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00056 | 21712 | 22410 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00056 | 22407 | 23780 | CPXAR | 0/0 | 100.0 | 99.5 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00007 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00013 | 92803 | 93691 | CTX | 0/0 | 100.0 | 97.4 | MEG_2430 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00085 | 6 | 503 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00055 | 5175 | 6347 | EMRA | 0/0 | 100.0 | 98.2 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00055 | 3620 | 5158 | EMRB | 0/0 | 100.0 | 99.9 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00009 | 22228 | 23418 | EMRD | 0/0 | 100.0 | 99.8 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00001 | 31510 | 32673 | EMRK | 0/0 | 100.0 | 99.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00055 | 6474 | 7004 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00001 | 29972 | 31510 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00030 | 18346 | 19989 | EPTA | 0/0 | 100.0 | 99.4 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00096 | 2354 | 3117 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00001 | 33708 | 37301 | EVGS | 0/0 | 100.0 | 99.6 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00020 | 31471 | 32199 | GADW | 0/0 | 100.0 | 98.6 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00020 | 32567 | 33391 | GADX | 0/0 | 100.0 | 97.9 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00018 | 10093 | 10506 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00045 | 8520 | 9192 | KDPE | 0/0 | 99.3 | 97.2 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00028 | 40679 | 41068 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00028 | 40231 | 40665 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00037 | 18321 | 19553 | MDFA | 0/0 | 100.0 | 98.5 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00013 | 55587 | 56834 | MDTA | 0/0 | 100.0 | 98.2 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00013 | 56834 | 59956 | MDTB | 0/0 | 100.0 | 98.0 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00013 | 59957 | 63034 | MDTC | 0/0 | 100.0 | 98.1 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00020 | 26813 | 27970 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00020 | 27995 | 31108 | MDTF | 0/0 | 100.0 | 98.5 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00006 | 121340 | 122566 | MDTG | 0/0 | 100.0 | 99.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00006 | 111501 | 112709 | MDTH | 0/0 | 100.0 | 98.5 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00022 | 35375 | 35704 | MDTI | 0/0 | 100.0 | 99.1 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00022 | 35023 | 35388 | MDTJ | 0/0 | 100.0 | 99.7 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00051 | 31774 | 33147 | MDTK | 0/0 | 100.0 | 99.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00019 | 52386 | 53618 | MDTM | 0/0 | 100.0 | 96.8 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00010 | 10863 | 11894 | MDTN | 0/0 | 100.0 | 98.1 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00010 | 11894 | 13945 | MDTO | 0/0 | 100.0 | 98.3 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00010 | 13942 | 15408 | MDTP | 0/0 | 100.0 | 98.2 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00096 | 268 | 1198 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00001 | 147653 | 148127 | MPHB | 0/0 | 99.6 | 97.5 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00003 | 31022 | 32770 | MSBA | 0/0 | 100.0 | 99.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00046 | 13699 | 15600 | PBP2 | 0/0 | 100.0 | 99.4 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00001 | 90842 | 92146 | PBP4B | 0/0 | 100.0 | 98.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00011 | 16717 | 17685 | PMRF | 0/0 | 100.0 | 99.5 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00064 | 11922 | 12791 | ROBA | 0/0 | 100.0 | 99.1 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00010 | 37024 | 37347 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00085 | 2206 | 3173 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00098 | 800 | 2005 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00098 | 2799 | 3215 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00032 | 30181 | 31824 | YOGI | 0/0 | 100.0 | 98.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00075 | 371 | 1246 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00089 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00128 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00009 | 30137 | 31369 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00139 | 68 | 998 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00089 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00123 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00001 | 99712 | 102861 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00068 | 11538 | 14651 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00058 | 8289 | 9446 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00058 | 5173 | 8277 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00058 | 9845 | 10507 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 90705 | 91526 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00049 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00049 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00012 | 48374 | 49747 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00010 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00075 | 371 | 1246 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00089 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00003 | 90366 | 91538 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00003 | 91555 | 93093 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00017 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00003 | 89709 | 90239 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00030 | 7608 | 9251 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00128 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00001 | 98496 | 99689 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 107745 | 108878 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00017 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00001 | 187826 | 188983 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00009 | 30137 | 31369 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00017 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00017 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00040 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00040 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00059 | 24580 | 24993 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00019 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00050 | 31344 | 31727 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00049 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00049 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00049 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00040 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00040 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00002 | 159289 | 160515 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00002 | 169144 | 170352 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00063 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00011 | 21720 | 22751 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00011 | 22751 | 24802 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00011 | 24799 | 26265 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00139 | 68 | 970 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00054 | 17756 | 18232 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00002 | 12783 | 14531 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00004 | 62210 | 63178 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00089 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00123 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00006 | 66840 | 68327 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 2107 | 3750 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00017 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00005 | 107745 | 108878 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00001 | 187826 | 188983 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00075 | 371 | 1246 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00019 | 60155 | 62056 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00128 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00139 | 68 | 970 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00089 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00123 | 850 | 2055 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00089 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00075 | 371 | 1246 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00005 | 107745 | 108878 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00089 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00128 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00139 | 68 | 998 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00089 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00123 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00001 | 98496 | 99689 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00001 | 99712 | 102861 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00068 | 11538 | 14651 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00058 | 8289 | 9446 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00058 | 5173 | 8277 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00058 | 9845 | 10507 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00005 | 107745 | 108878 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00001 | 187826 | 188983 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00089 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00049 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00006 | 90705 | 91526 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00049 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00049 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00020 | 49210 | 50400 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00012 | 47679 | 48377 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00012 | 48374 | 49747 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00010 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00143 | 62 | 1004 | CTX | 0/0 | 100.0 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00089 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00003 | 90366 | 91538 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00003 | 91555 | 93093 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00007 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00017 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00003 | 89709 | 90239 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00030 | 7608 | 9251 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00128 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00017 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00040 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00040 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00059 | 24580 | 24993 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00019 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00050 | 31338 | 31727 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00050 | 30890 | 31324 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00009 | 30137 | 31369 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00049 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00049 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00049 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00040 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00040 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00002 | 159289 | 160515 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00002 | 169144 | 170352 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00048 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00048 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00022 | 31959 | 33332 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00063 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00011 | 21720 | 22751 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00011 | 22751 | 24802 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00011 | 24799 | 26265 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00139 | 68 | 998 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00054 | 17756 | 18232 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00002 | 12783 | 14531 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00019 | 60155 | 62056 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00017 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00004 | 62210 | 63178 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00008 | 38665 | 39534 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00011 | 47882 | 48205 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00089 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00123 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00004 | 2107 | 3750 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00152 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00190 | 1684 | 2559 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00187 | 2039 | 2899 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00152 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00199 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00017 | 30174 | 31406 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00152 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00186 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00152 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00006 | 39318 | 42467 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00066 | 12933 | 16046 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00137 | 5381 | 8485 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00077 | 20439 | 21101 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 65835 | 66656 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00095 | 10772 | 11494 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00095 | 9372 | 10775 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00005 | 31213 | 32586 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00074 | 14885 | 15517 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00190 | 1684 | 2559 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00152 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00082 | 14502 | 15674 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00082 | 15691 | 17229 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00043 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00082 | 13845 | 14375 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00134 | 422 | 2065 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00199 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00006 | 38102 | 39295 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 103325 | 104458 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00068 | 19827 | 21131 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00012 | 35901 | 37058 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00017 | 30174 | 31406 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00043 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00043 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00046 | 1586 | 2314 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00046 | 394 | 1218 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00065 | 22020 | 22433 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00054 | 8962 | 9639 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00127 | 6406 | 6789 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00095 | 512 | 1759 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00095 | 1759 | 4881 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00095 | 4882 | 7959 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00046 | 5815 | 6972 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00046 | 2677 | 5790 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00030 | 16606 | 17832 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00030 | 26461 | 27669 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00069 | 262 | 1473 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00024 | 20208 | 21239 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00024 | 21239 | 23290 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00024 | 23287 | 24753 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00113 | 7732 | 8208 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00023 | 19048 | 20796 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00001 | 41659 | 42627 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00152 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00187 | 2039 | 2899 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00186 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00004 | 89034 | 90521 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00084 | 16770 | 18413 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00152 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00068 | 19827 | 21131 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00002 | 103325 | 104458 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00012 | 35901 | 37058 | (Bla)ampH_Ecoli | 0/0 | 100 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00190 | 1684 | 2559 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00187 | 2039 | 2899 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00136 | 3245 | 5146 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00199 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00152 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00186 | 850 | 2055 | (Tet)tetB | 0/0 | 100 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00152 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00152 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00190 | 1684 | 2559 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00002 | 103325 | 104458 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00187 | 2039 | 2899 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00152 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00199 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00152 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00186 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00006 | 38102 | 39295 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00006 | 39318 | 42467 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00066 | 12933 | 16046 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00137 | 5381 | 8485 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00077 | 20439 | 21101 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00002 | 103325 | 104458 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00012 | 35901 | 37058 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00152 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00093 | 11224 | 13076 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00004 | 65835 | 66656 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00095 | 10772 | 11494 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00095 | 9372 | 10775 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00005 | 30518 | 31216 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00005 | 31213 | 32586 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00074 | 14885 | 15517 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00239 | 61 | 987 | CTX | 0/0 | 98.3 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00152 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00082 | 14502 | 15674 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00082 | 15691 | 17229 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00133 | 7141 | 8331 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00043 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00082 | 13845 | 14375 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00134 | 422 | 2065 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00199 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00043 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00046 | 1586 | 2314 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00046 | 394 | 1218 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00065 | 22020 | 22433 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00054 | 8962 | 9639 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00127 | 6400 | 6789 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00127 | 5952 | 6386 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00017 | 30174 | 31406 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00095 | 512 | 1759 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00095 | 1759 | 4881 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00095 | 4882 | 7959 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00046 | 5815 | 6972 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00046 | 2677 | 5790 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00030 | 16606 | 17832 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00030 | 26461 | 27669 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00048 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00048 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00019 | 24050 | 25423 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00069 | 262 | 1473 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00024 | 20208 | 21239 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00024 | 21239 | 23290 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00024 | 23287 | 24753 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00113 | 7732 | 8208 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00023 | 19048 | 20796 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00136 | 3245 | 5146 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00068 | 19827 | 21131 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 41659 | 42627 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00015 | 19983 | 20852 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00024 | 46370 | 46693 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00152 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00186 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00084 | 16770 | 18413 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00028 | 43 | 903 | aac(3)-IIa_1 | 0/0 | 100 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00089 | 1540 | 2139 | aac(6’)-Ib-cr_1 | 0/0 | 100 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00081 | 843 | 1646 | aph(3’’)-Ib_5 | 0/0 | 100 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00081 | 7 | 843 | aph(6)-Id_1 | 0/0 | 100 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00064 | 2636 | 3511 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00089 | 579 | 1409 | blaOXA-1_1 | 0/0 | 100 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00093 | 534 | 1394 | blaTEM-1B_1 | 0/0 | 100 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00073 | 33 | 506 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00008 | 16349 | 17581 | mdf(A)_1 | 0/0 | 100 | 97.9 | Y08743 | mdf(A) | |
| contig00099 | 68 | 989 | mph(A)_2 | 1/1 | 100 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00081 | 1707 | 2522 | sul2_3 | 0/0 | 100 | 100.0 | HQ840942 | sul2 | Sulfamethoxazole |
| contig00080 | 770 | 1975 | tet(B)_2 | 0/0 | 100 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00028 | 43 | 903 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00089 | 1540 | 2139 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00024 | 932 | 4081 | acrB | 0/0 | 100.0 | 98.8 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00019 | 28484 | 31597 | acrD | 0/0 | 100.0 | 98.5 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00010 | 127224 | 128381 | acrE | 0/0 | 100.0 | 98.7 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00010 | 128393 | 131497 | acrF | 0/0 | 100.0 | 96.5 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00010 | 126163 | 126825 | acrS | 0/0 | 100.0 | 98.3 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00081 | 843 | 1646 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00081 | 7 | 843 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00004 | 65932 | 66753 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00023 | 10384 | 11105 | baeR | 0/0 | 99.9 | 96.7 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00023 | 11102 | 12505 | baeS | 0/0 | 100.0 | 90.6 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00014 | 107883 | 109250 | cpxA | 0/0 | 99.6 | 98.6 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00005 | 15383 | 16015 | CRP | 0/0 | 100.0 | 99.0 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00064 | 2636 | 3511 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00073 | 33 | 506 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00030 | 60820 | 61992 | emrA | 0/0 | 100.0 | 98.1 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00030 | 62009 | 63547 | emrB | 0/0 | 100.0 | 98.1 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00017 | 65261 | 66316 | emrK | 0/0 | 100.0 | 97.3 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00030 | 60163 | 60693 | emrR | 0/0 | 100.0 | 98.5 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00017 | 63723 | 65261 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00022 | 42665 | 44308 | eptA | 0/0 | 100.0 | 91.1 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00024 | 4104 | 5297 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.2 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00009 | 123964 | 125097 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00025 | 22923 | 24080 | Escherichia_coli_ampH | 0/0 | 100.0 | 97.2 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00028 | 62521 | 62853 | Escherichia_coli_emrE | 0/0 | 100.0 | 92.2 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00008 | 16349 | 17581 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.3 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00017 | 66840 | 67454 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00017 | 67459 | 71052 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00005 | 194273 | 195001 | gadW | 0/0 | 100.0 | 99.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00005 | 195370 | 196194 | gadX | 0/0 | 100.0 | 93.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00020 | 1686 | 2099 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00012 | 68376 | 69048 | kdpE | 0/0 | 99.3 | 95.8 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00043 | 8994 | 9377 | marA | 0/0 | 100.0 | 98.4 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00023 | 20118 | 21365 | mdtA | 0/0 | 100.0 | 95.8 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00023 | 16996 | 20118 | mdtB | 0/0 | 100.0 | 95.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00023 | 13918 | 16995 | mdtC | 0/0 | 100.0 | 93.9 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00005 | 189615 | 190772 | mdtE | 0/0 | 100.0 | 98.5 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00005 | 190797 | 193910 | mdtF | 0/0 | 100.0 | 97.3 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00011 | 69746 | 70972 | mdtG | 0/0 | 100.0 | 98.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00011 | 59907 | 61115 | mdtH | 0/0 | 100.0 | 98.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00022 | 12407 | 13438 | mdtN | 0/0 | 100.0 | 94.9 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00022 | 10356 | 12407 | mdtO | 0/0 | 100.0 | 97.1 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00022 | 8893 | 10359 | mdtP | 0/0 | 100.0 | 97.7 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00099 | 68 | 973 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00008 | 95721 | 97469 | msbA | 0/0 | 100.0 | 98.1 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00089 | 579 | 1409 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00003 | 185233 | 186201 | pmrF | 0/0 | 100.0 | 97.7 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00081 | 1707 | 2522 | sul2 | 0/0 | 100.0 | 99.6 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00093 | 534 | 1394 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00080 | 770 | 1975 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00004 | 89131 | 90618 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00023 | 75746 | 76912 | ugd | 0/0 | 100.0 | 97.0 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00003 | 125058 | 126701 | yojI | 0/0 | 100.0 | 97.9 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00028 | 43 | 903 | (AGly)aac3-IIa | 0/0 | 100 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00081 | 843 | 1646 | (AGly)strA | 0/0 | 100 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00081 | 7 | 843 | (AGly)strB | 0/0 | 100 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00009 | 123964 | 125097 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 98.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00025 | 22923 | 24080 | (Bla)ampH_Ecoli | 0/0 | 100 | 97.2 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00064 | 2636 | 3511 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00089 | 579 | 1409 | (Bla)blaOXA-1 | 0/0 | 100 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00093 | 534 | 1394 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00012 | 122036 | 123937 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 98.5 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00099 | 68 | 973 | (MLS)mph(A) | 0/0 | 100 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00081 | 1707 | 2522 | (Sul)sul2 | 0/0 | 100 | 99.6 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00080 | 770 | 1975 | (Tet)tetB | 0/0 | 100 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00073 | 33 | 506 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00028 | 43 | 903 | aac(3)-IIe | 0/0 | 100 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00089 | 1540 | 2094 | aac(6’)-Ib-D181Y | 0/0 | 100 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00081 | 843 | 1670 | aph(3’’)-Ib | 0/0 | 100 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00081 | 7 | 843 | aph(6)-Id | 0/0 | 100 | 100.0 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00064 | 2636 | 3511 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00009 | 123964 | 125097 | blaEC-5 | 0/0 | 100 | 99.8 | NG_049085.1 | cephalosporin-hydrolyzing class C beta-lactamase EC-5 | CEPHALOSPORIN |
| contig00089 | 579 | 1409 | blaOXA-1 | 0/0 | 100 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00093 | 534 | 1394 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00073 | 33 | 506 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00099 | 68 | 989 | mph(A) | 1/1 | 100 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00081 | 1707 | 2522 | sul2 | 0/0 | 100 | 99.9 | NG_048118.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00080 | 770 | 1975 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00028 | 43 | 903 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00024 | 4104 | 5297 | ACRA | 0/0 | 100.0 | 99.2 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00024 | 932 | 4081 | ACRB | 0/0 | 100.0 | 98.8 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00019 | 28484 | 31597 | ACRD | 0/0 | 100.0 | 98.5 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00010 | 127224 | 128381 | ACRE | 0/0 | 100.0 | 98.7 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00010 | 128393 | 131497 | ACRF | 0/0 | 100.0 | 96.5 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00010 | 126163 | 126825 | ACRS | 0/0 | 100.0 | 98.3 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00025 | 22923 | 24080 | AMPH | 0/0 | 100.0 | 97.2 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00081 | 843 | 1670 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00081 | 7 | 843 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00023 | 33028 | 34880 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00004 | 65932 | 66753 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00023 | 10384 | 11105 | BAER | 0/0 | 99.9 | 96.7 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00023 | 11102 | 12505 | BAES | 0/0 | 100.0 | 90.6 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00003 | 100400 | 101590 | BCR | 0/0 | 100.0 | 96.3 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00009 | 123964 | 125097 | BLAEC | 0/0 | 100.0 | 99.8 | MEG_1275 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00014 | 107188 | 107886 | CPXAR | 0/0 | 100.0 | 97.8 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00014 | 107883 | 109250 | CPXAR | 0/0 | 99.6 | 99.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00005 | 15383 | 16015 | CRP | 0/0 | 100.0 | 99.0 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00073 | 33 | 506 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00030 | 60820 | 61992 | EMRA | 0/0 | 100.0 | 98.1 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00030 | 62009 | 63547 | EMRB | 0/0 | 100.0 | 98.1 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00002 | 201125 | 202315 | EMRD | 0/0 | 100.0 | 97.7 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00017 | 65261 | 66424 | EMRK | 0/0 | 100.0 | 97.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00030 | 60163 | 60693 | EMRR | 0/0 | 100.0 | 98.5 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00017 | 63723 | 65261 | EMRY | 0/0 | 100.0 | 97.8 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00022 | 42665 | 44308 | EPTA | 0/0 | 100.0 | 91.1 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00017 | 67459 | 71052 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00005 | 194273 | 195001 | GADW | 0/0 | 100.0 | 99.7 | MEG_3082 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00005 | 195370 | 196194 | GADX | 0/0 | 100.0 | 93.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00020 | 1686 | 2099 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00012 | 68376 | 69048 | KDPE | 0/0 | 99.3 | 95.8 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00043 | 8994 | 9383 | MARA | 0/0 | 100.0 | 98.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00043 | 9398 | 9832 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00008 | 16349 | 17581 | MDFA | 0/0 | 100.0 | 98.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00023 | 20118 | 21365 | MDTA | 0/0 | 100.0 | 95.8 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00023 | 16996 | 20118 | MDTB | 0/0 | 100.0 | 95.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00023 | 13918 | 16995 | MDTC | 0/0 | 100.0 | 93.9 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00005 | 189615 | 190772 | MDTE | 0/0 | 100.0 | 98.5 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00005 | 190797 | 193910 | MDTF | 0/0 | 100.0 | 97.3 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00011 | 69746 | 70972 | MDTG | 0/0 | 100.0 | 98.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00011 | 59907 | 61115 | MDTH | 0/0 | 100.0 | 98.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00006 | 136641 | 136970 | MDTI | 0/0 | 100.0 | 98.8 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00006 | 136289 | 136654 | MDTJ | 0/0 | 100.0 | 97.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00006 | 54354 | 55726 | MDTK | 0/0 | 99.9 | 98.4 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00022 | 12407 | 13438 | MDTN | 0/0 | 100.0 | 94.9 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00022 | 10356 | 12407 | MDTO | 0/0 | 100.0 | 97.1 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00022 | 8893 | 10359 | MDTP | 0/0 | 100.0 | 97.7 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00099 | 68 | 989 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00008 | 95721 | 97469 | MSBA | 0/0 | 100.0 | 98.1 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00028 | 62521 | 62853 | MVRC | 0/0 | 100.0 | 92.2 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00089 | 579 | 1409 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00012 | 122036 | 123937 | PBP2 | 0/0 | 100.0 | 98.5 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00003 | 185233 | 186201 | PMRF | 0/0 | 100.0 | 97.7 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00013 | 41062 | 41931 | ROBA | 0/0 | 100.0 | 97.2 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00032 | 19176 | 19498 | SOXS | 0/0 | 99.7 | 98.1 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00081 | 1707 | 2522 | SULII | 0/0 | 100.0 | 100.0 | MEG_6618 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00093 | 516 | 1761 | TEM | 0/0 | 98.3 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00080 | 770 | 1975 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00080 | 2769 | 3185 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00023 | 75746 | 76912 | UGD | 0/0 | 100.0 | 97.0 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00003 | 125058 | 126701 | YOGI | 0/0 | 100.0 | 97.9 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00092 | 4914 | 5774 | aac(3)-IId_1 | 0/0 | 100.0 | 99.9 | EU022314 | aac(3)-IId | Gentamicin, Tobramycin |
| contig00002 | 187467 | 188342 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00124 | 88 | 729 | catA2_1 | 0/0 | 100.0 | 96.1 | X53796 | catA2 | Chloramphenicol |
| contig00036 | 1689 | 2162 | dfrA1_8 | 0/0 | 100.0 | 100.0 | X00926 | dfrA1 | Trimethoprim |
| contig00128 | 614 | 1111 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00001 | 101828 | 103060 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00130 | 68 | 989 | mph(A)_2 | 1/1 | 100.0 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00091 | 414 | 1280 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00094 | 2246 | 3037 | sul3_2 | 0/0 | 100.0 | 100.0 | AJ459418 | sul3 | Sulfamethoxazole |
| contig00101 | 2337 | 3583 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| contig00126 | 158 | 1425 | tet(K)_1 | 0/0 | 91.9 | 100.0 | U38656 | tet(K) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00092 | 4914 | 5774 | AAC(3)-IId | 0/0 | 100.0 | 99.9 | EU022314.1:0-861 | AAC(3)-IId is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00011 | 41403 | 44552 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00017 | 22104 | 25217 | acrD | 0/0 | 100.0 | 99.3 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00047 | 8641 | 9798 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00047 | 5525 | 8629 | acrF | 0/0 | 100.0 | 100.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00047 | 10197 | 10859 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 89700 | 90521 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00046 | 31115 | 31837 | baeR | 0/0 | 100.0 | 99.3 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00046 | 29715 | 31118 | baeS | 0/0 | 100.0 | 98.7 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00124 | 88 | 729 | catII_from_Escherichia_coli_K-12 | 0/0 | 100.0 | 96.1 | X53796.1:186-828 | catII is a chloramphenicol acetyltransferase. This particular catII is found in E.coli K-12. Confers resistance to chloramphenicol. | phenicol |
| contig00021 | 61537 | 62910 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00006 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00002 | 187467 | 188342 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00036 | 1689 | 2162 | dfrA1 | 0/0 | 100.0 | 99.8 | KJ541681.1:19526-20000 | dfrA1 is an integron-encoded dihydrofolate reductase | diaminopyrimidine |
| contig00128 | 614 | 1111 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00088 | 427 | 1599 | emrA | 0/0 | 100.0 | 99.9 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00088 | 1616 | 3154 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00010 | 108528 | 109583 | emrK | 0/0 | 100.0 | 99.9 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00010 | 106990 | 108528 | emrY | 0/0 | 100.0 | 99.9 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00004 | 178263 | 179906 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00011 | 40187 | 41380 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 134908 | 136041 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00017 | 56548 | 57852 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.7 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00033 | 27471 | 28628 | Escherichia_coli_ampH | 0/0 | 100.0 | 99.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00001 | 101828 | 103060 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00041 | 377 | 991 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00041 | 996 | 4589 | evgS | 0/0 | 100.0 | 100.0 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00038 | 2242 | 2970 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00038 | 1051 | 1875 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00053 | 23647 | 24060 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00020 | 8002 | 8679 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00044 | 28957 | 29340 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00046 | 20855 | 22102 | mdtA | 0/0 | 100.0 | 98.0 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00046 | 22102 | 25224 | mdtB | 0/0 | 100.0 | 97.0 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00046 | 25225 | 28302 | mdtC | 0/0 | 100.0 | 97.7 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00038 | 6471 | 7628 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00038 | 3333 | 6446 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00019 | 17779 | 19005 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00019 | 27634 | 28842 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00014 | 28251 | 29483 | mdtM | 0/0 | 100.0 | 96.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00012 | 10896 | 11927 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00012 | 11927 | 13978 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00012 | 13975 | 15441 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00130 | 68 | 973 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00017 | 944 | 1420 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00001 | 184776 | 186524 | msbA | 0/0 | 100.0 | 99.9 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00010 | 8072 | 9040 | pmrF | 0/0 | 100.0 | 99.9 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00094 | 734 | 1066 | qacH | 0/0 | 100.0 | 91.6 | DQ149925.1:188-521 | qacH is a subunit of the qac multidrug efflux pump in Vibrio cholerae | fluoroquinolone |
| contig00036 | 2257 | 2781 | SAT-1 | 0/0 | 100.0 | 100.0 | AB211124:0-525 | SAT-2 is a plasmid-mediated streptothricin acetyltransferase which confers resistance to streptothricin a nucleoside antibiotic. Originally described from an E. coli plasmid sequence by Heim et al. 1989. | nucleoside |
| contig00091 | 441 | 1280 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00094 | 2246 | 3037 | sul3 | 0/0 | 100.0 | 100.0 | FJ196385:9323-8531 | Sul3 is a sulfonamide resistant dihydropteroate synthase similar to Sul1 and Sul2. Its resistance gene was found encoded in E. coli plasmid DNA of sulfonamide resistant isolates. | sulfonamide |
| contig00101 | 2337 | 3583 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00126 | 158 | 1425 | tet(K) | 0/0 | 91.9 | 100.0 | S67449.1:0-1380 | TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species including mycobacteria) bacteria. | tetracycline |
| contig00005 | 65835 | 67322 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00025 | 50862 | 52505 | yojI | 0/0 | 100.0 | 99.9 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00092 | 4914 | 5774 | (AGly)aac3-IId | 0/0 | 100.0 | 99.9 | EU022314:1-861 | (AGly)aac3-IId | NA |
| contig00036 | 2828 | 3627 | (AGly)aadA1-pm | 1/3 | 96.3 | 99.5 | JQ690540:7968-8798 | (AGly)aadA1-pm | NA |
| contig00036 | 2257 | 2781 | (AGly)sat-2A | 0/0 | 100.0 | 100.0 | X51546:518-1042 | (AGly)sat-2A | NA |
| contig00017 | 56548 | 57852 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 98.7 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00004 | 134908 | 136041 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00033 | 27471 | 28628 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 99.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00002 | 187467 | 188342 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00020 | 60089 | 61990 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00130 | 68 | 973 | (MLS)mph(A) | 0/0 | 100.0 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00124 | 88 | 729 | (Phe)catA2 | 0/0 | 100.0 | 96.1 | X53796:187-903 | (Phe)catA2 | NA |
| contig00091 | 441 | 1280 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00094 | 2246 | 3037 | (Sul)sul3 | 0/0 | 100.0 | 100.0 | HQ875016:7396-8187 | (Sul)sul3 | NA |
| contig00101 | 2309 | 3583 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00126 | 158 | 1425 | (Tet)tetK | 0/0 | 91.9 | 100.0 | M16217:305-1684 | (Tet)tetK | NA |
| contig00101 | 3614 | 4264 | (Tet)tetR | 0/0 | 100.0 | 99.8 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00036 | 1689 | 2162 | (Tmt)dfrA1 | 0/0 | 100.0 | 100.0 | JQ794607:474 | (Tmt)dfrA1 | NA |
| contig00128 | 614 | 1111 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00092 | 4914 | 5774 | aac(3)-IId | 0/0 | 100.0 | 100.0 | NG_047251.1 | aminoglycoside N-acetyltransferase AAC(3)-IId | GENTAMICIN |
| contig00036 | 2839 | 3627 | aadA1 | 0/0 | 100.0 | 100.0 | NG_047327.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA1 | STREPTOMYCIN |
| contig00002 | 187467 | 188342 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00004 | 134908 | 136041 | blaEC | 0/0 | 100.0 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00124 | 88 | 729 | catA2 | 0/0 | 100.0 | 100.0 | NG_047596.1 | type A-2 chloramphenicol O-acetyltransferase CatII | CHLORAMPHENICOL |
| contig00036 | 1689 | 2162 | dfrA1 | 0/0 | 100.0 | 100.0 | NG_047676.1 | trimethoprim-resistant dihydrofolate reductase DfrA1 | TRIMETHOPRIM |
| contig00128 | 614 | 1111 | dfrA12 | 0/0 | 100.0 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00130 | 68 | 989 | mph(A) | 1/1 | 100.0 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00036 | 2257 | 2781 | sat2_gen | 0/0 | 100.0 | 100.0 | NG_048068.1 | streptothricin N-acetyltransferase Sat2 | STREPTOTHRICIN |
| contig00091 | 441 | 1280 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00094 | 2246 | 3037 | sul3 | 0/0 | 100.0 | 100.0 | NG_048120.1 | sulfonamide-resistant dihydropteroate synthase Sul3 | SULFONAMIDE |
| contig00101 | 2309 | 3508 | tet(A) | 0/0 | 100.0 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| contig00126 | 158 | 1425 | tet(K) | 0/0 | 91.9 | 100.0 | NG_048200.1 | tetracycline efflux MFS transporter Tet(K) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00092 | 4914 | 5774 | AAC3 | 0/0 | 100.0 | 100.0 | MEG_64 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00011 | 40187 | 41380 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00011 | 41403 | 44552 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00017 | 22104 | 25217 | ACRD | 0/0 | 100.0 | 99.3 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00047 | 8641 | 9798 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00047 | 5525 | 8629 | ACRF | 0/0 | 100.0 | 100.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00047 | 10197 | 10859 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00004 | 134908 | 136041 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00033 | 27471 | 28628 | AMPH | 0/0 | 100.0 | 99.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00036 | 2828 | 3627 | ANT3-DPRIME | 1/3 | 96.3 | 99.5 | MEG_915 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00046 | 6739 | 8591 | ASMA | 0/0 | 100.0 | 97.2 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00005 | 89700 | 90521 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00046 | 31115 | 31837 | BAER | 0/0 | 100.0 | 99.3 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00046 | 29715 | 31118 | BAES | 0/0 | 100.0 | 98.7 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00015 | 67340 | 68530 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00124 | 88 | 729 | CATA | 0/0 | 100.0 | 100.0 | MEG_1568 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00021 | 60842 | 61540 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00021 | 61537 | 62910 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00006 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00090 | 3505 | 4447 | CTX | 0/0 | 100.0 | 98.1 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00112 | 334 | 1222 | CTX | 0/0 | 100.0 | 95.4 | MEG_2430 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00036 | 1689 | 2162 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2495 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00128 | 614 | 1111 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00088 | 427 | 1599 | EMRA | 0/0 | 100.0 | 99.9 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00088 | 1616 | 3154 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00008 | 87250 | 88440 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00010 | 108528 | 109686 | EMRK | 0/0 | 99.6 | 99.9 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00010 | 106990 | 108528 | EMRY | 0/0 | 100.0 | 99.9 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00004 | 178263 | 179906 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00041 | 996 | 4589 | EVGS | 0/0 | 100.0 | 100.0 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00038 | 2242 | 2970 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00038 | 1051 | 1875 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00053 | 23647 | 24060 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00020 | 8002 | 8679 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00044 | 28951 | 29340 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00044 | 28503 | 28937 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00001 | 101828 | 103060 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00046 | 20855 | 22102 | MDTA | 0/0 | 100.0 | 98.0 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00046 | 22102 | 25224 | MDTB | 0/0 | 100.0 | 97.0 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00046 | 25225 | 28302 | MDTC | 0/0 | 100.0 | 97.7 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00038 | 6471 | 7628 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00038 | 3333 | 6446 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00019 | 17779 | 19005 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00019 | 27634 | 28842 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00042 | 632 | 961 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00042 | 948 | 1313 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00009 | 76121 | 77494 | MDTK | 0/0 | 100.0 | 100.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00014 | 28251 | 29483 | MDTM | 0/0 | 100.0 | 96.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00012 | 10896 | 11927 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00012 | 11927 | 13978 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00012 | 13975 | 15441 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00130 | 68 | 989 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00017 | 944 | 1420 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00001 | 184776 | 186524 | MSBA | 0/0 | 100.0 | 99.9 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00020 | 60089 | 61990 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00017 | 56548 | 57852 | PBP4B | 0/0 | 100.0 | 98.7 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00010 | 8072 | 9040 | PMRF | 0/0 | 100.0 | 99.9 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00094 | 734 | 1066 | QACL | 0/0 | 100.0 | 100.0 | MEG_5852 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:QACL | NA |
| contig00003 | 175115 | 175984 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00012 | 37058 | 37381 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00091 | 440 | 1407 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00094 | 2246 | 3037 | SULIII | 0/0 | 100.0 | 100.0 | MEG_6639 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULIII | NA |
| contig00101 | 2309 | 3583 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00126 | 158 | 1425 | TETK | 0/0 | 91.9 | 100.0 | MEG_7089 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETK | NA |
| contig00025 | 50862 | 52505 | YOGI | 0/0 | 100.0 | 99.9 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1392 | 2180 | aadA5_1 | 0/0 | 100 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00078 | 498 | 1373 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00094 | 788 | 1261 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00002 | 154454 | 155686 | mdf(A)_1 | 0/0 | 100 | 98.3 | Y08743 | mdf(A) | |
| contig00094 | 8861 | 9782 | mph(A)_2 | 1/1 | 100 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00078 | 6014 | 6670 | qnrS1_1 | 0/0 | 100 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| contig00094 | 2700 | 3566 | sul1_5 | 0/0 | 100 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1392 | 2180 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00001 | 103356 | 106505 | acrB | 0/0 | 100.0 | 99.5 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 71682 | 74795 | acrD | 0/0 | 100.0 | 98.9 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00058 | 8406 | 9563 | acrE | 0/0 | 100.0 | 99.0 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00058 | 5290 | 8394 | acrF | 0/0 | 100.0 | 99.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00058 | 9962 | 10624 | acrS | 0/0 | 100.0 | 98.9 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00019 | 28559 | 29380 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00002 | 50563 | 51285 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00002 | 49163 | 50566 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00035 | 37431 | 38804 | cpxA | 0/0 | 100.0 | 98.7 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00005 | 15464 | 16096 | CRP | 0/0 | 100.0 | 99.8 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00078 | 498 | 1373 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00094 | 788 | 1261 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00003 | 27410 | 28582 | emrA | 0/0 | 100.0 | 99.9 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00003 | 28599 | 30137 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00046 | 8783 | 9838 | emrK | 0/0 | 100.0 | 99.9 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00003 | 26753 | 27283 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00046 | 7245 | 8783 | emrY | 0/0 | 100.0 | 98.9 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00013 | 76745 | 78388 | eptA | 0/0 | 100.0 | 99.3 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00001 | 106528 | 107721 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00013 | 33384 | 34517 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.6 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00006 | 106194 | 107498 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 96.9 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00001 | 17240 | 18397 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00002 | 154454 | 155686 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.8 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00046 | 10362 | 10976 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00046 | 10981 | 14574 | evgS | 0/0 | 100.0 | 100.0 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00042 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00042 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00025 | 5169 | 5582 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00007 | 23675 | 24352 | kdpE | 0/0 | 100.0 | 99.7 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00054 | 31308 | 31691 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 40303 | 41550 | mdtA | 0/0 | 100.0 | 99.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00002 | 41550 | 44672 | mdtB | 0/0 | 100.0 | 99.8 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00002 | 44673 | 47750 | mdtC | 0/0 | 100.0 | 99.8 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00042 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00042 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00004 | 124760 | 125986 | mdtG | 0/0 | 100.0 | 99.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00004 | 114922 | 116130 | mdtH | 0/0 | 100.0 | 97.9 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00061 | 6012 | 7244 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00055 | 1 | 2040 | mdtO | 0/0 | 99.4 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00055 | 2037 | 3503 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00094 | 8877 | 9782 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00006 | 50468 | 50944 | mphB | 0/0 | 100.0 | 98.1 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00011 | 81416 | 83164 | msbA | 0/0 | 100.0 | 99.9 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00080 | 1339 | 2307 | pmrF | 0/0 | 100.0 | 99.8 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00078 | 6014 | 6670 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00094 | 2727 | 3566 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00087 | 5852 | 7339 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00023 | 56976 | 58619 | yojI | 0/0 | 100.0 | 99.3 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1392 | 2180 | (AGly)aadA5 | 0/0 | 100 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00006 | 106194 | 107498 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 96.9 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00013 | 33384 | 34517 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.6 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00001 | 17240 | 18397 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00078 | 498 | 1373 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00007 | 76088 | 77989 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 99.7 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00078 | 6014 | 6670 | (Flq)qnr-S1 | 0/0 | 100 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| contig00094 | 8877 | 9782 | (MLS)mph(A) | 0/0 | 100 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00094 | 2727 | 3566 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00094 | 788 | 1261 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1392 | 2180 | aadA5 | 0/0 | 100 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00078 | 498 | 1373 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00013 | 33384 | 34517 | blaEC-18 | 0/0 | 100 | 99.1 | NG_049083.1 | class C extended-spectrum beta-lactamase EC-18 | CEPHALOSPORIN |
| contig00094 | 788 | 1261 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00094 | 8861 | 9782 | mph(A) | 1/1 | 100 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00078 | 6014 | 6670 | qnrS1 | 0/0 | 100 | 100.0 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| contig00094 | 2727 | 3566 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00001 | 106528 | 107721 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00001 | 103356 | 106505 | ACRB | 0/0 | 100.0 | 99.5 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00006 | 71682 | 74795 | ACRD | 0/0 | 100.0 | 98.9 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00058 | 8406 | 9563 | ACRE | 0/0 | 100.0 | 99.0 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00058 | 5290 | 8394 | ACRF | 0/0 | 100.0 | 99.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00058 | 9962 | 10624 | ACRS | 0/0 | 100.0 | 98.9 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00001 | 17240 | 18397 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00094 | 1392 | 2180 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00002 | 26048 | 27900 | ASMA | 0/0 | 100.0 | 98.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00019 | 28559 | 29380 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00002 | 50563 | 51285 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00002 | 49163 | 50566 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00039 | 19164 | 20354 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00013 | 33384 | 34517 | BLAEC | 0/0 | 100.0 | 99.1 | MEG_1279 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00035 | 36736 | 37434 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00035 | 37431 | 38804 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00005 | 15464 | 16096 | CRP | 0/0 | 100.0 | 99.8 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00094 | 788 | 1261 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00003 | 27410 | 28582 | EMRA | 0/0 | 100.0 | 99.9 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00003 | 28599 | 30137 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00016 | 28895 | 30085 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00046 | 8783 | 9946 | EMRK | 0/0 | 100.0 | 99.9 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00003 | 26753 | 27283 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00046 | 7245 | 8783 | EMRY | 0/0 | 100.0 | 99.0 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00013 | 76745 | 78388 | EPTA | 0/0 | 100.0 | 99.3 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00046 | 10981 | 14574 | EVGS | 0/0 | 100.0 | 100.0 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00042 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00042 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00025 | 5169 | 5582 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00007 | 23675 | 24352 | KDPE | 0/0 | 100.0 | 99.7 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00054 | 31302 | 31691 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00054 | 30854 | 31288 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00002 | 154454 | 155686 | MDFA | 0/0 | 100.0 | 98.4 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00002 | 40303 | 41550 | MDTA | 0/0 | 100.0 | 99.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00002 | 41550 | 44672 | MDTB | 0/0 | 100.0 | 99.8 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00002 | 44673 | 47750 | MDTC | 0/0 | 100.0 | 99.8 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00042 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00042 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00004 | 124760 | 125986 | MDTG | 0/0 | 100.0 | 99.9 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00004 | 114922 | 116130 | MDTH | 0/0 | 100.0 | 97.9 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00010 | 80532 | 80861 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00010 | 80180 | 80545 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00010 | 8883 | 10256 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00061 | 6012 | 7244 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00055 | 1 | 2040 | MDTO | 0/0 | 99.4 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00055 | 2037 | 3503 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00094 | 8861 | 9782 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00006 | 50468 | 50944 | MPHB | 0/0 | 100.0 | 98.1 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00011 | 81416 | 83164 | MSBA | 0/0 | 100.0 | 99.9 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00007 | 76088 | 77989 | PBP2 | 0/0 | 100.0 | 99.7 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00006 | 106194 | 107498 | PBP4B | 0/0 | 100.0 | 96.9 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00080 | 1339 | 2307 | PMRF | 0/0 | 100.0 | 99.8 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00078 | 6014 | 6670 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00044 | 21726 | 22595 | ROBA | 0/0 | 100.0 | 98.8 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00055 | 25459 | 25781 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00094 | 2726 | 3693 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00023 | 56976 | 58619 | YOGI | 0/0 | 100.0 | 99.3 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00114 | 1172 | 1973 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig02536 | 13 | 816 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00117 | 2038 | 2838 | blaCTX-M-156_1 | 0/0 | 91.4 | 100.0 | KM211509 | blaCTX-M-156 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00114 | 2371 | 2868 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig01746 | 253 | 1013 | erm(B)_18 | 2/2 | 99.6 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00055 | 865 | 2097 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig01661 | 68 | 998 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00962 | 11 | 826 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00114 | 1172 | 1951 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00367 | 1254 | 1916 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig02536 | 13 | 816 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00117 | 2038 | 2838 | CTX-M-15 | 0/0 | 91.4 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00114 | 2371 | 2868 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00254 | 1 | 1481 | eptA | 0/0 | 90.1 | 100.0 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig01746 | 279 | 1013 | ErmB | 0/0 | 98.4 | 99.3 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00232 | 144 | 1277 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00055 | 865 | 2097 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig01603 | 277 | 954 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig02480 | 237 | 566 | Klebsiella_pneumoniae_KpnF | 0/0 | 100.0 | 100.0 | AP006725.1:2484238-2484568 | KpnF subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime ceftriaxon colistin erythromycin rifampin tetracycline and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate deoxycholate dyes benzalkonium chloride chlorhexidine and triclosan. | aminoglycoside, cephalosporin, macrolide, peptide, rifamycin, tetracycline |
| contig00796 | 225 | 1455 | mdtA | 0/0 | 98.6 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00549 | 519 | 1697 | mdtG | 0/0 | 96.1 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00148 | 918 | 2384 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig01661 | 68 | 970 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00802 | 918 | 1394 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00962 | 11 | 826 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00114 | 1172 | 1951 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig02536 | 13 | 816 | (AGly)strA | 0/0 | 100.0 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00232 | 144 | 1277 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00117 | 2038 | 2838 | (Bla)blaCTX-M-15 | 0/0 | 91.4 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig01746 | 279 | 1013 | (MLS)erm(B) | 0/0 | 99.6 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig01661 | 68 | 970 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00962 | 11 | 826 | (Sul)sul2 | 0/0 | 100.0 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00114 | 2371 | 2868 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00114 | 1172 | 1963 | aadA2 | 0/0 | 100.0 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig02536 | 13 | 822 | aph(3’’)-Ib | 0/0 | 97.8 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00117 | 2038 | 2838 | blaCTX-M-15 | 0/0 | 91.4 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00232 | 144 | 1277 | blaEC | 0/0 | 100.0 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00114 | 2371 | 2868 | dfrA12 | 0/0 | 100.0 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig01746 | 279 | 1013 | erm(B) | 0/0 | 99.6 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig01661 | 68 | 998 | mph(A) | 2/10 | 100.0 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00962 | 11 | 826 | sul2 | 0/0 | 100.0 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00367 | 1254 | 1916 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00232 | 144 | 1277 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00114 | 1172 | 1973 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig02536 | 13 | 822 | APH3-DPRIME | 0/0 | 97.8 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00482 | 1 | 1665 | ASMA | 0/0 | 91.3 | 99.1 | MEG_1179 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig03658 | 1 | 636 | CPXAR | 0/0 | 91.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00114 | 2371 | 2868 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00254 | 1 | 1481 | EPTA | 0/0 | 90.1 | 100.0 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig01746 | 253 | 1013 | ERMB | 2/2 | 99.6 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig01603 | 277 | 954 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig02480 | 237 | 566 | KPNF | 0/0 | 100.0 | 100.0 | MEG_3515 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:KPNF | NA |
| contig00055 | 865 | 2097 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00796 | 225 | 1455 | MDTA | 0/0 | 98.6 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00549 | 519 | 1697 | MDTG | 0/0 | 96.1 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00148 | 918 | 2384 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig01661 | 68 | 998 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00802 | 918 | 1394 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00332 | 36 | 359 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00962 | 11 | 826 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00009 | 91518 | 92393 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00089 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00125 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00008 | 30310 | 31542 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00089 | 10161 | 11091 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00089 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00118 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00007 | 99712 | 102861 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00027 | 52378 | 55491 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00062 | 21524 | 22681 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00062 | 20463 | 21125 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 89049 | 89870 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00053 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00053 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00005 | 61439 | 62812 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00003 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00009 | 91518 | 92393 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00089 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00069 | 11909 | 13081 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00069 | 13098 | 14636 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00020 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00069 | 11252 | 11782 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00016 | 46590 | 48233 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00125 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00007 | 98496 | 99689 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00017 | 13415 | 14548 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00020 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00012 | 64067 | 65224 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00008 | 30310 | 31542 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00020 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00020 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00042 | 2699 | 3427 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00042 | 1507 | 2331 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00059 | 24863 | 25276 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00024 | 8065 | 8742 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00053 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00053 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00053 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00042 | 6928 | 8085 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00042 | 3790 | 6903 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00038 | 16626 | 17852 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00038 | 26481 | 27689 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00061 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00016 | 16021 | 17052 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00016 | 13970 | 16021 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00016 | 12507 | 13973 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00089 | 10189 | 11091 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00027 | 31216 | 31692 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00002 | 51374 | 53122 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00001 | 136290 | 137258 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00089 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00118 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00006 | 65184 | 66671 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 76187 | 77830 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00020 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00017 | 13415 | 14548 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00012 | 64067 | 65224 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00009 | 91518 | 92393 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00024 | 60152 | 62053 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00125 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00089 | 10189 | 11091 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00089 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00118 | 850 | 2055 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00089 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00089 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00009 | 91518 | 92393 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00017 | 13415 | 14548 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00089 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00125 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00089 | 10161 | 11091 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00089 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00118 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00007 | 98496 | 99689 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00007 | 99712 | 102861 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00027 | 52378 | 55491 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00062 | 21524 | 22681 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00062 | 20463 | 21125 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00017 | 13415 | 14548 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00012 | 64067 | 65224 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00089 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00053 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00006 | 89049 | 89870 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00053 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00053 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 49210 | 50400 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00005 | 60744 | 61442 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00005 | 61439 | 62812 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00003 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00146 | 62 | 1004 | CTX | 0/0 | 100.0 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00089 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00069 | 11909 | 13081 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00069 | 13098 | 14636 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00004 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00020 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00069 | 11252 | 11782 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00016 | 46590 | 48233 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00125 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00020 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00042 | 2699 | 3427 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00042 | 1507 | 2331 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00059 | 24863 | 25276 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00024 | 8065 | 8742 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00056 | 30890 | 31324 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00008 | 30310 | 31542 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00053 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00053 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00053 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00042 | 6928 | 8085 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00042 | 3790 | 6903 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00038 | 16626 | 17852 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00038 | 26481 | 27689 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00050 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00050 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00026 | 31960 | 33333 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00061 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00016 | 16021 | 17052 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00016 | 13970 | 16021 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00016 | 12507 | 13973 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00089 | 10161 | 11091 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00027 | 31216 | 31692 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00002 | 51374 | 53122 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00024 | 60152 | 62053 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00020 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 136290 | 137258 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00063 | 4214 | 5083 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00025 | 9090 | 9413 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00089 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00118 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00001 | 76187 | 77830 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00074 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00023 | 6419 | 7294 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00074 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00103 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00001 | 82540 | 83772 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00074 | 10161 | 11091 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00074 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00099 | 1132 | 2337 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00074 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00003 | 99712 | 102861 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00022 | 71642 | 74755 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00049 | 8641 | 9798 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00049 | 5525 | 8629 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00049 | 10197 | 10859 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 90602 | 91423 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00044 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00044 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00010 | 61323 | 62696 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00007 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00023 | 6419 | 7294 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00074 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00005 | 90366 | 91538 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00005 | 91555 | 93093 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00021 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00005 | 89709 | 90239 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00032 | 7757 | 9400 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00103 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00003 | 98496 | 99689 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00011 | 40938 | 42071 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00021 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00003 | 187826 | 188983 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00001 | 82540 | 83772 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00021 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00021 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00040 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00040 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00033 | 47705 | 48118 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00025 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00045 | 31344 | 31727 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00044 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00044 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00044 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00040 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00040 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00001 | 311993 | 313219 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00001 | 321848 | 323056 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00053 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00013 | 21757 | 22788 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00013 | 22788 | 24839 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00013 | 24836 | 26302 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00074 | 10189 | 11091 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00022 | 50480 | 50956 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00001 | 165487 | 167235 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00002 | 173705 | 174673 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00074 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00099 | 1132 | 2337 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00006 | 66737 | 68224 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 113602 | 115245 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00074 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00021 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00011 | 40938 | 42071 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00003 | 187826 | 188983 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00023 | 6419 | 7294 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00025 | 60155 | 62056 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00103 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00074 | 10189 | 11091 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00074 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00099 | 1132 | 2337 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00074 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00074 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00023 | 6419 | 7294 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00011 | 40938 | 42071 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00074 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00103 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00074 | 10161 | 11091 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00074 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00099 | 1132 | 2337 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00003 | 98496 | 99689 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00003 | 99712 | 102861 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00022 | 71642 | 74755 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00049 | 8641 | 9798 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00049 | 5525 | 8629 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00049 | 10197 | 10859 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00011 | 40938 | 42071 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00003 | 187826 | 188983 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00074 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00044 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00006 | 90602 | 91423 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00044 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00044 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00002 | 86625 | 87815 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00010 | 60628 | 61326 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00010 | 61323 | 62696 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00007 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00121 | 62 | 1004 | CTX | 0/0 | 100.0 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00074 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00005 | 90366 | 91538 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00005 | 91555 | 93093 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00008 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00021 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00005 | 89709 | 90239 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00032 | 7757 | 9400 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00103 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00021 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00040 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00040 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00033 | 47705 | 48118 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00025 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00045 | 31338 | 31727 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00045 | 30890 | 31324 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00001 | 82540 | 83772 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00044 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00044 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00044 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00040 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00040 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00001 | 311993 | 313219 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00001 | 321848 | 323056 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00043 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00043 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00027 | 31963 | 33336 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00053 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00013 | 21757 | 22788 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00013 | 22788 | 24839 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00013 | 24836 | 26302 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00074 | 10161 | 11091 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00022 | 50480 | 50956 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00001 | 165487 | 167235 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00025 | 60155 | 62056 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00021 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00002 | 173705 | 174673 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00004 | 19983 | 20852 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00013 | 47919 | 48242 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00074 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00099 | 1132 | 2337 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00002 | 113602 | 115245 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00014 | 91518 | 92393 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00073 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00099 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00001 | 84130 | 85362 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00110 | 68 | 998 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00073 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00094 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00002 | 39346 | 42495 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00023 | 71642 | 74755 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00008 | 127797 | 128954 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00008 | 128966 | 132070 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00008 | 126736 | 127398 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 90602 | 91423 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00048 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00048 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00011 | 61323 | 62696 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00007 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00014 | 91518 | 92393 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00073 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00006 | 90366 | 91538 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00006 | 91555 | 93093 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00022 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00006 | 89709 | 90239 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00034 | 1544 | 3187 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00099 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00002 | 38130 | 39323 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 107745 | 108878 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00022 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00002 | 127460 | 128617 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00001 | 84130 | 85362 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00022 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00022 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00042 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00042 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00036 | 43265 | 43678 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00025 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00049 | 31344 | 31727 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00048 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00048 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00048 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00042 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00042 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00035 | 19640 | 20866 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00035 | 29495 | 30703 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00055 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00016 | 10928 | 11959 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00016 | 11959 | 14010 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00016 | 14007 | 15473 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00110 | 68 | 970 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00023 | 50480 | 50956 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00001 | 167077 | 168825 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00003 | 136373 | 137341 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00073 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00094 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00005 | 66737 | 68224 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 76270 | 77913 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00022 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00004 | 107745 | 108878 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00002 | 127460 | 128617 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00014 | 91518 | 92393 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00025 | 60155 | 62056 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00099 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00110 | 68 | 970 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00073 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00094 | 850 | 2055 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00073 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00014 | 91518 | 92393 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00004 | 107745 | 108878 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00073 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00099 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00110 | 68 | 998 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00073 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00094 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00002 | 38130 | 39323 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00002 | 39346 | 42495 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00023 | 71642 | 74755 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00008 | 127797 | 128954 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00008 | 128966 | 132070 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00008 | 126736 | 127398 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00004 | 107745 | 108878 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00002 | 127460 | 128617 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00073 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00048 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00005 | 90602 | 91423 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00048 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00048 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00003 | 49293 | 50483 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00011 | 60628 | 61326 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00011 | 61323 | 62696 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00007 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00116 | 61 | 984 | CTX | 0/0 | 98.0 | 98.3 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00073 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00006 | 90366 | 91538 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00006 | 91555 | 93093 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00009 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00022 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00006 | 89709 | 90239 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00034 | 1544 | 3187 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00099 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00022 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00042 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00042 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00036 | 43265 | 43678 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00025 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00049 | 31338 | 31727 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00049 | 30890 | 31324 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00001 | 84130 | 85362 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00048 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00048 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00048 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00042 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00042 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00035 | 19640 | 20866 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00035 | 29495 | 30703 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00046 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00046 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00026 | 31963 | 33336 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00055 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00016 | 10928 | 11959 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00016 | 11959 | 14010 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00016 | 14007 | 15473 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00110 | 68 | 998 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00023 | 50480 | 50956 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00001 | 167077 | 168825 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00025 | 60155 | 62056 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00022 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00003 | 136373 | 137341 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00013 | 38665 | 39534 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00016 | 37090 | 37413 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00073 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00094 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00003 | 76270 | 77913 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00034 | 6419 | 7294 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00079 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00102 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00013 | 30137 | 31369 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00124 | 68 | 954 | mph(A)_1 | 0/0 | 97.9 | 99.9 | D16251 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00079 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00097 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00010 | 98538 | 101687 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 135260 | 138373 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00051 | 8445 | 9602 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00051 | 5329 | 8433 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00051 | 10001 | 10663 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 90701 | 91522 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00047 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00047 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00009 | 61323 | 62696 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00007 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00034 | 6419 | 7294 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00079 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00014 | 19623 | 20795 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00014 | 20812 | 22350 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00024 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00014 | 18966 | 19496 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00003 | 120344 | 121987 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00102 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00010 | 101710 | 102903 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 107745 | 108878 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00024 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00010 | 12416 | 13573 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00013 | 30137 | 31369 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00024 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00024 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00042 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00042 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00020 | 91674 | 92087 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00027 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00048 | 31519 | 31902 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00047 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00047 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00047 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00042 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00042 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00035 | 16784 | 18010 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00035 | 26639 | 27847 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00058 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00003 | 89775 | 90806 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00003 | 87724 | 89775 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00003 | 86261 | 87727 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00124 | 68 | 954 | mphA | 0/0 | 97.9 | 99.9 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00006 | 114098 | 114574 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00001 | 125547 | 127295 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00004 | 62214 | 63182 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00079 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00097 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00005 | 66836 | 68323 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 2111 | 3754 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00024 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00002 | 107745 | 108878 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00010 | 12416 | 13573 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00034 | 6419 | 7294 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00027 | 60155 | 62056 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00102 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00124 | 68 | 954 | (MLS)mph(A) | 0/0 | 97.9 | 99.9 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00079 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00097 | 850 | 2055 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00079 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2731 | 3522 | aadA2 | 0/0 | 100.0 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00034 | 6419 | 7294 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00002 | 107745 | 108878 | blaEC | 0/0 | 100.0 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00079 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00102 | 289 | 1026 | erm(B) | 0/0 | 100.0 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00124 | 68 | 954 | mph(A) | 0/0 | 97.9 | 99.9 | NG_047985.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00079 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00097 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00010 | 101710 | 102903 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00010 | 98538 | 101687 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00006 | 135260 | 138373 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00051 | 8445 | 9602 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00051 | 5329 | 8433 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00051 | 10001 | 10663 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00002 | 107745 | 108878 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00010 | 12416 | 13573 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00079 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00047 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00005 | 90701 | 91522 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00047 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00047 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 23569 | 24759 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00009 | 60628 | 61326 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 61323 | 62696 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00007 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00123 | 62 | 988 | CTX | 0/0 | 98.3 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00079 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00014 | 19623 | 20795 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00014 | 20812 | 22350 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00008 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00024 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00014 | 18966 | 19496 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00003 | 120344 | 121987 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00102 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00024 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00042 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00042 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00020 | 91674 | 92087 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00027 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00048 | 31513 | 31902 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00048 | 31065 | 31499 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00013 | 30137 | 31369 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00047 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00047 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00047 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00042 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00042 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00035 | 16784 | 18010 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00035 | 26639 | 27847 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00017 | 103532 | 103861 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00017 | 103180 | 103545 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00017 | 31959 | 33332 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00058 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00003 | 89775 | 90806 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00003 | 87724 | 89775 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00003 | 86261 | 87727 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00124 | 68 | 954 | MPHA | 0/0 | 97.9 | 99.9 | MEG_4029 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00006 | 114098 | 114574 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00001 | 125547 | 127295 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00027 | 60155 | 62056 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00024 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00004 | 62214 | 63182 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00012 | 38665 | 39534 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00003 | 64321 | 64644 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00079 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00097 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00004 | 2111 | 3754 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 1 | 834 | aph(6)-Id_1 | 0/0 | 99.6 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00031 | 2385 | 3260 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00087 | 73 | 555 | dfrA14_5 | 0/0 | 100.0 | 99.8 | DQ388123 | dfrA14 | Trimethoprim |
| contig00067 | 1489 | 2062 | dfrA7_5 | 3/4 | 100.0 | 98.8 | AJ419170 | dfrA7 | Trimethoprim |
| contig00006 | 5438 | 6670 | mdf(A)_1 | 0/0 | 100.0 | 98.0 | Y08743 | mdf(A) | |
| contig00067 | 179 | 1045 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00050 | 8201 | 9447 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00027 | 21643 | 24792 | acrB | 0/0 | 100.0 | 98.8 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 378940 | 382053 | acrD | 0/0 | 100.0 | 98.4 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00013 | 130114 | 131271 | acrE | 0/0 | 100.0 | 98.8 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00013 | 131283 | 134387 | acrF | 0/0 | 100.0 | 97.2 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00013 | 129053 | 129715 | acrS | 0/0 | 100.0 | 98.3 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00079 | 1 | 834 | APH(6)-Id | 0/0 | 99.6 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00003 | 237652 | 238471 | bacA | 0/0 | 99.8 | 98.2 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00034 | 25847 | 26568 | baeR | 0/0 | 99.9 | 97.1 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00034 | 24447 | 25850 | baeS | 0/0 | 100.0 | 90.6 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00023 | 29347 | 30720 | cpxA | 0/0 | 100.0 | 98.5 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15384 | 16016 | CRP | 0/0 | 100.0 | 99.0 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00031 | 2385 | 3260 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00087 | 73 | 555 | dfrA14 | 0/0 | 100.0 | 100.0 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00067 | 1589 | 2062 | dfrA7 | 0/0 | 100.0 | 100.0 | FJ854362:2338-2812 | dfrA7 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00010 | 36139 | 37311 | emrA | 0/0 | 100.0 | 98.1 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00010 | 37328 | 38866 | emrB | 0/0 | 100.0 | 97.9 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00001 | 285170 | 286225 | emrK | 0/0 | 100.0 | 97.8 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00010 | 35482 | 36012 | emrR | 0/0 | 100.0 | 98.5 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00001 | 283632 | 285170 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00025 | 3860 | 5503 | eptA | 0/0 | 100.0 | 91.2 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00027 | 24815 | 26008 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.2 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00028 | 12860 | 13993 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.5 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00004 | 225178 | 226335 | Escherichia_coli_ampH | 0/0 | 100.0 | 97.2 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00011 | 113754 | 114086 | Escherichia_coli_emrE | 0/0 | 100.0 | 91.9 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00006 | 5438 | 6670 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00001 | 286749 | 287363 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00001 | 287368 | 290961 | evgS | 0/0 | 100.0 | 96.2 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00009 | 196304 | 197032 | gadW | 0/0 | 100.0 | 99.9 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00009 | 197401 | 198225 | gadX | 0/0 | 100.0 | 93.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00015 | 31236 | 31649 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00016 | 7188 | 7860 | kdpE | 0/0 | 99.3 | 95.8 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00026 | 22140 | 22523 | marA | 0/0 | 100.0 | 98.7 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00034 | 15587 | 16834 | mdtA | 0/0 | 100.0 | 95.8 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00034 | 16834 | 19956 | mdtB | 0/0 | 100.0 | 95.4 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00034 | 19957 | 23034 | mdtC | 0/0 | 100.0 | 92.3 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00009 | 191646 | 192803 | mdtE | 0/0 | 100.0 | 98.5 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00009 | 192828 | 195941 | mdtF | 0/0 | 100.0 | 97.3 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00021 | 77335 | 78561 | mdtG | 0/0 | 100.0 | 98.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00021 | 67496 | 68704 | mdtH | 0/0 | 100.0 | 98.3 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00033 | 12206 | 13237 | mdtN | 0/0 | 100.0 | 95.1 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00033 | 10155 | 12206 | mdtO | 0/0 | 100.0 | 96.7 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00033 | 8692 | 10158 | mdtP | 0/0 | 100.0 | 97.6 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00006 | 130260 | 132008 | msbA | 0/0 | 100.0 | 98.1 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00001 | 185259 | 186227 | pmrF | 0/0 | 100.0 | 97.8 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00067 | 179 | 1018 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00050 | 8201 | 9447 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00003 | 210380 | 211867 | tolC | 0/0 | 100.0 | 98.2 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00020 | 40454 | 41620 | ugd | 0/0 | 100.0 | 96.1 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00001 | 125373 | 127016 | yojI | 0/0 | 100.0 | 98.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 1 | 834 | (AGly)strB | 0/0 | 99.6 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00028 | 12860 | 13993 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 97.5 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00004 | 225178 | 226335 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 97.2 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00031 | 2385 | 3260 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00016 | 60848 | 62749 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 98.6 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00067 | 179 | 1018 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00050 | 8173 | 9447 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00050 | 9478 | 10128 | (Tet)tetR | 0/0 | 100.0 | 100.0 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00087 | 73 | 546 | (Tmt)dfrA14 | 0/0 | 100.0 | 99.8 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| contig00067 | 1589 | 2062 | (Tmt)dhfr7 | 0/0 | 100.0 | 100.0 | X58425:594-1067 | (Tmt)dhfr7 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 1 | 834 | aph(6)-Id | 0/0 | 99.6 | 100 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00031 | 2385 | 3260 | blaCTX-M-15 | 0/0 | 100.0 | 100 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00028 | 12860 | 13993 | blaEC-19 | 0/0 | 100.0 | 99 | NG_049084.1 | class C extended-spectrum beta-lactamase EC-19 | CEPHALOSPORIN |
| contig00087 | 73 | 546 | dfrA14 | 0/0 | 100.0 | 100 | NG_047696.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| contig00067 | 1589 | 2062 | dfrA7 | 0/0 | 100.0 | 100 | NG_047737.1 | trimethoprim-resistant dihydrofolate reductase DfrA7 | TRIMETHOPRIM |
| contig00067 | 179 | 1018 | sul1 | 0/0 | 100.0 | 100 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00050 | 8173 | 9372 | tet(A) | 0/0 | 100.0 | 100 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00027 | 24815 | 26008 | ACRA | 0/0 | 100.0 | 99.2 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00027 | 21643 | 24792 | ACRB | 0/0 | 100.0 | 98.8 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00001 | 378940 | 382053 | ACRD | 0/0 | 100.0 | 98.4 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00013 | 130114 | 131271 | ACRE | 0/0 | 100.0 | 98.8 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00013 | 131283 | 134387 | ACRF | 0/0 | 100.0 | 97.2 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00013 | 129053 | 129715 | ACRS | 0/0 | 100.0 | 98.3 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00004 | 225178 | 226335 | AMPH | 0/0 | 100.0 | 97.2 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00079 | 1 | 834 | APH6 | 0/0 | 99.6 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00034 | 2073 | 3925 | ASMA | 0/0 | 100.0 | 97.7 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00003 | 237652 | 238471 | BACA | 0/0 | 99.8 | 98.4 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00034 | 25847 | 26568 | BAER | 0/0 | 99.9 | 97.1 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00034 | 24447 | 25850 | BAES | 0/0 | 100.0 | 90.6 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 100550 | 101740 | BCR | 0/0 | 100.0 | 96.3 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00028 | 12860 | 13993 | BLAEC | 0/0 | 100.0 | 99.0 | MEG_1275 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00023 | 28652 | 29350 | CPXAR | 0/0 | 100.0 | 97.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00023 | 29347 | 30720 | CPXAR | 0/0 | 100.0 | 98.9 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15384 | 16016 | CRP | 0/0 | 100.0 | 99.0 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00051 | 7643 | 8585 | CTX | 0/0 | 100.0 | 98.9 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00067 | 1589 | 2062 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2548 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00087 | 73 | 546 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00010 | 36139 | 37311 | EMRA | 0/0 | 100.0 | 98.1 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00010 | 37328 | 38866 | EMRB | 0/0 | 100.0 | 97.9 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00008 | 132845 | 134035 | EMRD | 0/0 | 100.0 | 98.1 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00001 | 285170 | 286333 | EMRK | 0/0 | 100.0 | 97.6 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00010 | 35482 | 36012 | EMRR | 0/0 | 100.0 | 98.5 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00001 | 283632 | 285170 | EMRY | 0/0 | 100.0 | 97.8 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00025 | 3860 | 5503 | EPTA | 0/0 | 100.0 | 91.2 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00001 | 287368 | 290961 | EVGS | 0/0 | 100.0 | 97.3 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00009 | 196304 | 197032 | GADW | 0/0 | 100.0 | 99.9 | MEG_3082 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00009 | 197401 | 198225 | GADX | 0/0 | 100.0 | 93.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00015 | 31236 | 31649 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00016 | 7188 | 7860 | KDPE | 0/0 | 99.3 | 95.8 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00026 | 22134 | 22523 | MARA | 0/0 | 100.0 | 98.7 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00026 | 21685 | 22119 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00006 | 5438 | 6670 | MDFA | 0/0 | 100.0 | 98.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00034 | 15587 | 16834 | MDTA | 0/0 | 100.0 | 95.8 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00034 | 16834 | 19956 | MDTB | 0/0 | 100.0 | 95.4 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00034 | 19957 | 23034 | MDTC | 0/0 | 100.0 | 92.3 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00009 | 191646 | 192803 | MDTE | 0/0 | 100.0 | 98.5 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00009 | 192828 | 195941 | MDTF | 0/0 | 100.0 | 97.3 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00021 | 77335 | 78561 | MDTG | 0/0 | 100.0 | 98.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00021 | 67496 | 68704 | MDTH | 0/0 | 100.0 | 98.3 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00026 | 60188 | 60517 | MDTI | 0/0 | 100.0 | 98.5 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00026 | 60504 | 60869 | MDTJ | 0/0 | 100.0 | 98.4 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00005 | 36829 | 38202 | MDTK | 0/0 | 100.0 | 97.9 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00033 | 12206 | 13237 | MDTN | 0/0 | 100.0 | 95.1 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00033 | 10155 | 12206 | MDTO | 0/0 | 100.0 | 96.7 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00033 | 8692 | 10158 | MDTP | 0/0 | 100.0 | 97.6 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00006 | 130260 | 132008 | MSBA | 0/0 | 100.0 | 98.1 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00011 | 113754 | 114086 | MVRC | 0/0 | 100.0 | 91.9 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00016 | 60848 | 62749 | PBP2 | 0/0 | 100.0 | 98.6 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00001 | 185259 | 186227 | PMRF | 0/0 | 100.0 | 97.8 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00002 | 119196 | 120065 | ROBA | 0/0 | 100.0 | 97.1 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00022 | 19233 | 19555 | SOXS | 0/0 | 99.7 | 98.1 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00067 | 52 | 1019 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00050 | 8173 | 9447 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00020 | 40454 | 41620 | UGD | 0/0 | 100.0 | 96.1 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00001 | 125373 | 127016 | YOGI | 0/0 | 100.0 | 98.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 1696 | 2556 | aac(3)-IIa_1 | 0/0 | 100.0 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00076 | 1540 | 2139 | aac(6’)-Ib-cr_1 | 0/0 | 100.0 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00057 | 1303 | 2091 | aadA5_1 | 0/0 | 100.0 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00050 | 8895 | 9698 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00050 | 8059 | 8895 | aph(6)-Id_1 | 0/0 | 100.0 | 99.9 | M28829 | aph(6)-Id | Streptomycin |
| contig00002 | 201260 | 202135 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00076 | 579 | 1409 | blaOXA-1_1 | 0/0 | 100.0 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00057 | 699 | 1172 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00017 | 29907 | 31139 | mdf(A)_1 | 0/0 | 100.0 | 97.8 | Y08743 | mdf(A) | |
| contig00081 | 69 | 990 | mph(A)_2 | 1/1 | 100.0 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00057 | 2611 | 3477 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00050 | 9759 | 10574 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00050 | 5810 | 7056 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 1696 | 2556 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00076 | 1540 | 2139 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00057 | 1303 | 2091 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00001 | 65991 | 69140 | acrB | 0/0 | 100.0 | 98.8 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 99480 | 102593 | acrD | 0/0 | 100.0 | 98.7 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00012 | 149292 | 150449 | acrE | 0/0 | 100.0 | 98.8 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00012 | 150461 | 153565 | acrF | 0/0 | 100.0 | 96.6 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00012 | 148231 | 148893 | acrS | 0/0 | 100.0 | 98.3 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00050 | 8895 | 9698 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00050 | 8059 | 8895 | APH(6)-Id | 0/0 | 100.0 | 99.8 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00007 | 52237 | 53056 | bacA | 0/0 | 99.8 | 98.3 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00013 | 61611 | 62332 | baeR | 0/0 | 99.9 | 97.1 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00013 | 62329 | 63732 | baeS | 0/0 | 100.0 | 90.5 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00018 | 66690 | 68057 | cpxA | 0/0 | 99.6 | 98.5 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00008 | 15089 | 15721 | CRP | 0/0 | 100.0 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00002 | 201260 | 202135 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00057 | 699 | 1172 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00029 | 60267 | 61439 | emrA | 0/0 | 100.0 | 98.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00029 | 61456 | 62994 | emrB | 0/0 | 100.0 | 98.4 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00005 | 5710 | 6765 | emrK | 0/0 | 100.0 | 97.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00029 | 59610 | 60140 | emrR | 0/0 | 100.0 | 98.5 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00005 | 4172 | 5710 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00009 | 146400 | 148043 | eptA | 0/0 | 100.0 | 91.4 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00001 | 64775 | 65968 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.1 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00032 | 30615 | 31748 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.8 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00001 | 153890 | 155047 | Escherichia_coli_ampH | 0/0 | 100.0 | 97.1 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00014 | 28735 | 29067 | Escherichia_coli_emrE | 0/0 | 100.0 | 92.2 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00017 | 29907 | 31139 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.3 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00005 | 7289 | 7903 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00005 | 7908 | 11501 | evgS | 0/0 | 100.0 | 96.3 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00008 | 188688 | 189416 | gadW | 0/0 | 100.0 | 100.0 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00008 | 189785 | 190609 | gadX | 0/0 | 100.0 | 93.9 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00025 | 39538 | 39951 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00006 | 53994 | 54666 | kdpE | 0/0 | 99.3 | 95.5 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00026 | 29733 | 30116 | marA | 0/0 | 100.0 | 99.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00013 | 71345 | 72592 | mdtA | 0/0 | 100.0 | 95.6 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00013 | 68223 | 71345 | mdtB | 0/0 | 100.0 | 96.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00013 | 65145 | 68222 | mdtC | 0/0 | 100.0 | 94.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00008 | 184030 | 185187 | mdtE | 0/0 | 100.0 | 98.5 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00008 | 185212 | 188325 | mdtF | 0/0 | 100.0 | 97.3 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00011 | 91920 | 93146 | mdtG | 0/0 | 100.0 | 98.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00011 | 82083 | 83291 | mdtH | 0/0 | 100.0 | 98.3 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00031 | 38742 | 39974 | mdtM | 0/0 | 100.0 | 95.0 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00009 | 116127 | 117158 | mdtN | 0/0 | 100.0 | 96.2 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00009 | 114076 | 116127 | mdtO | 0/0 | 100.0 | 97.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00009 | 112613 | 114079 | mdtP | 0/0 | 100.0 | 97.6 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00081 | 69 | 974 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00023 | 5695 | 7443 | msbA | 0/0 | 100.0 | 98.1 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00076 | 579 | 1409 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00004 | 171344 | 172312 | pmrF | 0/0 | 100.0 | 97.6 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00057 | 2638 | 3477 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00050 | 9759 | 10574 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00050 | 5810 | 7056 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00007 | 78739 | 80226 | tolC | 0/0 | 100.0 | 98.2 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00013 | 125688 | 126854 | ugd | 0/0 | 100.0 | 96.0 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00004 | 111496 | 113139 | yojI | 0/0 | 100.0 | 97.4 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 1696 | 2556 | (AGly)aac3-IIa | 0/0 | 100 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00057 | 1303 | 2091 | (AGly)aadA5 | 0/0 | 100 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00050 | 8895 | 9698 | (AGly)strA | 0/0 | 100 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00050 | 8059 | 8895 | (AGly)strB | 0/0 | 100 | 99.9 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00032 | 30615 | 31748 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.8 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00001 | 153890 | 155047 | (Bla)ampH_Ecoli | 0/0 | 100 | 97.1 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00002 | 201260 | 202135 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00076 | 579 | 1409 | (Bla)blaOXA-1 | 0/0 | 100 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00006 | 113211 | 115112 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 98.7 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00081 | 69 | 974 | (MLS)mph(A) | 0/0 | 100 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00057 | 2638 | 3477 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00050 | 9759 | 10574 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00050 | 5782 | 7056 | (Tet)tetA | 0/0 | 100 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00050 | 7087 | 7737 | (Tet)tetR | 0/0 | 100 | 100.0 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00057 | 699 | 1172 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 1696 | 2556 | aac(3)-IIe | 0/0 | 100 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00076 | 1540 | 2094 | aac(6’)-Ib-D181Y | 0/0 | 100 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00057 | 1303 | 2091 | aadA5 | 0/0 | 100 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00050 | 8895 | 9722 | aph(3’’)-Ib | 0/0 | 100 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00050 | 8059 | 8895 | aph(6)-Id | 0/0 | 100 | 100.0 | NG_047466.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00002 | 201260 | 202135 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00032 | 30615 | 31748 | blaEC-5 | 0/0 | 100 | 99.5 | NG_049085.1 | cephalosporin-hydrolyzing class C beta-lactamase EC-5 | CEPHALOSPORIN |
| contig00076 | 579 | 1409 | blaOXA-1 | 0/0 | 100 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00057 | 699 | 1172 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00081 | 69 | 990 | mph(A) | 1/1 | 100 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00057 | 2638 | 3477 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00050 | 9759 | 10574 | sul2 | 0/0 | 100 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00050 | 5782 | 6981 | tet(A) | 0/0 | 100 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00073 | 1696 | 2556 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00001 | 64775 | 65968 | ACRA | 0/0 | 100.0 | 99.1 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00001 | 65991 | 69140 | ACRB | 0/0 | 100.0 | 98.8 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00005 | 99480 | 102593 | ACRD | 0/0 | 100.0 | 98.7 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00012 | 149292 | 150449 | ACRE | 0/0 | 100.0 | 98.8 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00012 | 150461 | 153565 | ACRF | 0/0 | 100.0 | 96.6 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00012 | 148231 | 148893 | ACRS | 0/0 | 100.0 | 98.3 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00001 | 153890 | 155047 | AMPH | 0/0 | 100.0 | 97.1 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00057 | 1303 | 2091 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00050 | 8895 | 9722 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00050 | 8059 | 8895 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1084 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00013 | 84252 | 86104 | ASMA | 0/0 | 100.0 | 97.6 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00007 | 52237 | 53056 | BACA | 0/0 | 99.8 | 98.5 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00013 | 61611 | 62332 | BAER | 0/0 | 99.9 | 97.1 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00013 | 62329 | 63732 | BAES | 0/0 | 100.0 | 90.5 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00004 | 86673 | 87863 | BCR | 0/0 | 100.0 | 96.6 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00032 | 30615 | 31748 | BLAEC | 0/0 | 100.0 | 99.5 | MEG_1275 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00018 | 65995 | 66693 | CPXAR | 0/0 | 100.0 | 98.1 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00018 | 66690 | 68057 | CPXAR | 0/0 | 99.6 | 99.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00008 | 15089 | 15721 | CRP | 0/0 | 100.0 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00057 | 699 | 1172 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00029 | 60267 | 61439 | EMRA | 0/0 | 100.0 | 98.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00029 | 61456 | 62994 | EMRB | 0/0 | 100.0 | 98.4 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00002 | 194231 | 195421 | EMRD | 0/0 | 100.0 | 97.5 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00005 | 5710 | 6873 | EMRK | 0/0 | 100.0 | 97.4 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00029 | 59610 | 60140 | EMRR | 0/0 | 100.0 | 98.5 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00005 | 4172 | 5710 | EMRY | 0/0 | 100.0 | 97.7 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00009 | 146400 | 148043 | EPTA | 0/0 | 100.0 | 91.4 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00005 | 7908 | 11501 | EVGS | 0/0 | 100.0 | 97.4 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00008 | 188688 | 189416 | GADW | 0/0 | 100.0 | 100.0 | MEG_3082 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00008 | 189785 | 190609 | GADX | 0/0 | 100.0 | 93.9 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00025 | 39538 | 39951 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00006 | 53994 | 54666 | KDPE | 0/0 | 99.3 | 95.5 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00026 | 29727 | 30116 | MARA | 0/0 | 100.0 | 99.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00026 | 29278 | 29712 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00017 | 29907 | 31139 | MDFA | 0/0 | 100.0 | 97.9 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00013 | 71345 | 72592 | MDTA | 0/0 | 100.0 | 95.6 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00013 | 68223 | 71345 | MDTB | 0/0 | 100.0 | 96.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00013 | 65145 | 68222 | MDTC | 0/0 | 100.0 | 94.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00008 | 184030 | 185187 | MDTE | 0/0 | 100.0 | 98.5 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00008 | 185212 | 188325 | MDTF | 0/0 | 100.0 | 97.3 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00011 | 91920 | 93146 | MDTG | 0/0 | 100.0 | 98.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00011 | 82083 | 83291 | MDTH | 0/0 | 100.0 | 98.3 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00026 | 60681 | 61010 | MDTI | 0/0 | 100.0 | 98.8 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00026 | 60997 | 61362 | MDTJ | 0/0 | 100.0 | 98.4 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00021 | 60316 | 61688 | MDTK | 0/0 | 99.9 | 97.7 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00031 | 38742 | 39974 | MDTM | 0/0 | 100.0 | 95.0 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00009 | 116127 | 117158 | MDTN | 0/0 | 100.0 | 96.2 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00009 | 114076 | 116127 | MDTO | 0/0 | 100.0 | 97.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00009 | 112613 | 114079 | MDTP | 0/0 | 100.0 | 97.6 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00081 | 69 | 990 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00023 | 5695 | 7443 | MSBA | 0/0 | 100.0 | 98.1 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00014 | 28735 | 29067 | MVRC | 0/0 | 100.0 | 92.2 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00076 | 579 | 1409 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00006 | 113211 | 115112 | PBP2 | 0/0 | 100.0 | 98.7 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00004 | 171344 | 172312 | PMRF | 0/0 | 100.0 | 97.6 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00003 | 19703 | 20572 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00009 | 84260 | 84582 | SOXS | 0/0 | 99.7 | 98.1 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00057 | 2637 | 3604 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00050 | 9759 | 10574 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00050 | 5782 | 7056 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00013 | 125688 | 126854 | UGD | 0/0 | 100.0 | 96.0 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00004 | 111496 | 113139 | YOGI | 0/0 | 100.0 | 97.4 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00060 | 19123 | 19926 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00060 | 18287 | 19123 | aph(6)-Id_1 | 0/0 | 100.0 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00060 | 15299 | 16174 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00096 | 183 | 665 | dfrA14_5 | 0/0 | 100.0 | 99.6 | DQ388123 | dfrA14 | Trimethoprim |
| contig00048 | 27861 | 29093 | mdf(A)_1 | 0/0 | 100.0 | 99.0 | Y08743 | mdf(A) | |
| contig00060 | 10002 | 10658 | qnrS1_1 | 0/0 | 100.0 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| contig00060 | 19987 | 20802 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00091 | 1676 | 2922 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00040 | 38756 | 41905 | acrB | 0/0 | 100.0 | 99.5 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00012 | 71770 | 74883 | acrD | 0/0 | 100.0 | 99.3 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00003 | 144696 | 145853 | acrE | 0/0 | 100.0 | 99.0 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00003 | 145865 | 148969 | acrF | 0/0 | 100.0 | 99.1 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00003 | 143635 | 144297 | acrS | 0/0 | 100.0 | 98.9 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00060 | 19123 | 19926 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00060 | 18287 | 19123 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00016 | 65363 | 66184 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00008 | 91520 | 92242 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00008 | 90120 | 91523 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00014 | 61321 | 62694 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00004 | 14925 | 15557 | CRP | 0/0 | 100.0 | 99.8 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00060 | 15299 | 16174 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00096 | 183 | 665 | dfrA14 | 0/0 | 100.0 | 99.8 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00053 | 28123 | 29295 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00053 | 29312 | 30850 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00050 | 3675 | 4730 | emrK | 0/0 | 100.0 | 99.8 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00053 | 27466 | 27996 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00050 | 2137 | 3675 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00026 | 7717 | 9360 | eptA | 0/0 | 100.0 | 99.5 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00040 | 37540 | 38733 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.5 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00026 | 51573 | 52706 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.3 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00045 | 14217 | 15521 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.7 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00009 | 17331 | 18488 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00048 | 27861 | 29093 | Escherichia_coli_mdfA | 0/0 | 100.0 | 97.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00050 | 5254 | 5868 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00050 | 5873 | 9466 | evgS | 0/0 | 100.0 | 100.0 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00042 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00042 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00007 | 118839 | 119252 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00039 | 8002 | 8679 | kdpE | 0/0 | 100.0 | 99.4 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00017 | 46177 | 46560 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 81260 | 82507 | mdtA | 0/0 | 100.0 | 100.0 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00008 | 82507 | 85629 | mdtB | 0/0 | 100.0 | 98.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00008 | 85630 | 88707 | mdtC | 0/0 | 100.0 | 99.8 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00042 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00042 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00049 | 24804 | 26030 | mdtG | 0/0 | 100.0 | 99.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00049 | 14968 | 16176 | mdtH | 0/0 | 100.0 | 98.3 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00056 | 8672 | 9883 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00010 | 89191 | 90222 | mdtN | 0/0 | 100.0 | 99.5 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00010 | 87140 | 89191 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00010 | 85677 | 87143 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00012 | 50610 | 51086 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00006 | 2197 | 3945 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00002 | 62175 | 63143 | pmrF | 0/0 | 100.0 | 99.9 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00060 | 10002 | 10658 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00060 | 19987 | 20802 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00091 | 1676 | 2922 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00016 | 41500 | 42987 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 2050 | 3693 | yojI | 0/0 | 100.0 | 99.9 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00060 | 19123 | 19926 | (AGly)strA | 0/0 | 100 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00060 | 18287 | 19123 | (AGly)strB | 0/0 | 100 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00045 | 14217 | 15521 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 98.7 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00026 | 51573 | 52706 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.3 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00009 | 17331 | 18488 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00060 | 15299 | 16174 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00067 | 8261 | 10162 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 99.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00060 | 10002 | 10658 | (Flq)qnr-S1 | 0/0 | 100 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| contig00060 | 19987 | 20802 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00091 | 1648 | 2922 | (Tet)tetA | 0/0 | 100 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00096 | 183 | 656 | (Tmt)dfrA14 | 0/0 | 100 | 100.0 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00060 | 19123 | 19950 | aph(3’’)-Ib | 0/0 | 100 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00060 | 18287 | 19123 | aph(6)-Id | 0/0 | 100 | 100.0 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00060 | 15299 | 16174 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00026 | 51573 | 52706 | blaEC | 0/0 | 100 | 98.2 | NG_047496.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00096 | 183 | 656 | dfrA14 | 0/0 | 100 | 100.0 | NG_056035.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| contig00060 | 10002 | 10658 | qnrS1 | 0/0 | 100 | 100.0 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| contig00060 | 19987 | 20802 | sul2 | 0/0 | 100 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00091 | 1648 | 2847 | tet(A) | 0/0 | 100 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00040 | 37540 | 38733 | ACRA | 0/0 | 100.0 | 99.5 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00040 | 38756 | 41905 | ACRB | 0/0 | 100.0 | 99.5 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00012 | 71770 | 74883 | ACRD | 0/0 | 100.0 | 99.3 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00003 | 144696 | 145853 | ACRE | 0/0 | 100.0 | 99.0 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00003 | 145865 | 148969 | ACRF | 0/0 | 100.0 | 99.1 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00003 | 143635 | 144297 | ACRS | 0/0 | 100.0 | 98.9 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00009 | 17331 | 18488 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00060 | 19123 | 19950 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00060 | 18287 | 19123 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00008 | 66995 | 68847 | ASMA | 0/0 | 100.0 | 98.1 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00016 | 65363 | 66184 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00008 | 91520 | 92242 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00008 | 90120 | 91523 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00021 | 49342 | 50532 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00026 | 51573 | 52706 | BLAEC | 0/0 | 100.0 | 98.2 | MEG_1276 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00014 | 60626 | 61324 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00014 | 61321 | 62694 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00004 | 14925 | 15557 | CRP | 0/0 | 100.0 | 99.8 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00076 | 132 | 1074 | CTX | 0/0 | 100.0 | 99.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00096 | 183 | 656 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00053 | 28123 | 29295 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00053 | 29312 | 30850 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00027 | 16748 | 17938 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00050 | 3675 | 4838 | EMRK | 0/0 | 100.0 | 99.8 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00053 | 27466 | 27996 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00050 | 2137 | 3675 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00026 | 7717 | 9360 | EPTA | 0/0 | 100.0 | 99.5 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00050 | 5873 | 9466 | EVGS | 0/0 | 100.0 | 100.0 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00042 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00042 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00007 | 118839 | 119252 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00039 | 8002 | 8679 | KDPE | 0/0 | 100.0 | 99.4 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00017 | 46171 | 46560 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00017 | 45723 | 46157 | MARR | 0/0 | 100.0 | 99.8 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00048 | 27861 | 29093 | MDFA | 0/0 | 100.0 | 99.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00008 | 81260 | 82507 | MDTA | 0/0 | 100.0 | 100.0 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00008 | 82507 | 85629 | MDTB | 0/0 | 100.0 | 98.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00008 | 85630 | 88707 | MDTC | 0/0 | 100.0 | 99.8 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00042 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00042 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00049 | 24804 | 26030 | MDTG | 0/0 | 100.0 | 99.9 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00049 | 14968 | 16176 | MDTH | 0/0 | 100.0 | 98.3 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00001 | 210422 | 210751 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00001 | 210070 | 210435 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00001 | 138668 | 140041 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00056 | 8672 | 9883 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00010 | 89191 | 90222 | MDTN | 0/0 | 100.0 | 99.5 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00010 | 87140 | 89191 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00010 | 85677 | 87143 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00012 | 50610 | 51086 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00006 | 2197 | 3945 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00067 | 8261 | 10162 | PBP2 | 0/0 | 100.0 | 99.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00045 | 14217 | 15521 | PBP4B | 0/0 | 100.0 | 98.7 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00002 | 62175 | 63143 | PMRF | 0/0 | 100.0 | 99.9 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00060 | 10002 | 10658 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00029 | 38115 | 38984 | ROBA | 0/0 | 100.0 | 98.8 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00010 | 63398 | 63720 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00060 | 19987 | 20802 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00091 | 1648 | 2922 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00002 | 2050 | 3693 | YOGI | 0/0 | 100.0 | 99.9 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00070 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00080 | 6419 | 7294 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00070 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00101 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00015 | 30313 | 31545 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00112 | 68 | 998 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00070 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00098 | 1132 | 2337 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00070 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00002 | 99712 | 102861 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00032 | 38918 | 42031 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00010 | 127797 | 128954 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00010 | 128966 | 132070 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00010 | 126736 | 127398 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 90602 | 91423 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00043 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00043 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00013 | 61200 | 62573 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00080 | 6419 | 7294 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00070 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00005 | 90366 | 91538 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00005 | 91555 | 93093 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00023 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00005 | 89709 | 90239 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00007 | 120014 | 121657 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00101 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00002 | 98496 | 99689 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 107745 | 108878 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00023 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00002 | 187826 | 188983 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00015 | 30313 | 31545 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00023 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00023 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00038 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00038 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00018 | 91674 | 92087 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00076 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00044 | 31343 | 31726 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00043 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00043 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00043 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00038 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00038 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00034 | 18401 | 19627 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00034 | 28256 | 29464 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00051 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00007 | 89445 | 90476 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00007 | 87394 | 89445 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00007 | 85931 | 87397 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00112 | 68 | 970 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00032 | 17756 | 18232 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00006 | 51374 | 53122 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00001 | 173705 | 174673 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00070 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00098 | 1132 | 2337 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00008 | 66737 | 68224 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 113602 | 115245 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00070 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00023 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00004 | 107745 | 108878 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00002 | 187826 | 188983 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00080 | 6419 | 7294 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00026 | 51171 | 53072 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00101 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00112 | 68 | 970 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00070 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00098 | 1132 | 2337 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00070 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00070 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00080 | 6419 | 7294 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00004 | 107745 | 108878 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00070 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00101 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00112 | 68 | 998 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00070 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00098 | 1132 | 2337 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00002 | 98496 | 99689 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00002 | 99712 | 102861 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00032 | 38918 | 42031 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00010 | 127797 | 128954 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00010 | 128966 | 132070 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00010 | 126736 | 127398 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00004 | 107745 | 108878 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00002 | 187826 | 188983 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00070 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00043 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00008 | 90602 | 91423 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00043 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00043 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 86625 | 87815 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00013 | 60505 | 61203 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00013 | 61200 | 62573 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00120 | 62 | 1004 | CTX | 0/0 | 100.0 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00070 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00005 | 90366 | 91538 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00005 | 91555 | 93093 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00011 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00023 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00005 | 89709 | 90239 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00007 | 120014 | 121657 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00101 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00023 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00038 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00038 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00018 | 91674 | 92087 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00076 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00044 | 31337 | 31726 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00044 | 30889 | 31323 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00015 | 30313 | 31545 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00043 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00043 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00043 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00038 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00038 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00034 | 18401 | 19627 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00034 | 28256 | 29464 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00042 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00042 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00037 | 31963 | 33336 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00051 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00007 | 89445 | 90476 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00007 | 87394 | 89445 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00007 | 85931 | 87397 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00112 | 68 | 998 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00032 | 17756 | 18232 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00006 | 51374 | 53122 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00026 | 51171 | 53072 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00023 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 173705 | 174673 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00003 | 28156 | 29025 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00007 | 63991 | 64314 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00070 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00098 | 1132 | 2337 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00001 | 113602 | 115245 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00042 | 6419 | 7294 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00079 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00109 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00007 | 67552 | 68784 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00120 | 68 | 998 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00079 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00103 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00001 | 39392 | 42541 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 135351 | 138464 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00011 | 127888 | 129045 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00011 | 129057 | 132161 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00011 | 126827 | 127489 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00010 | 90602 | 91423 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00047 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00047 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00013 | 61323 | 62696 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15750 | 16382 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00042 | 6419 | 7294 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00079 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00004 | 90366 | 91538 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00004 | 91555 | 93093 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00021 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00004 | 89709 | 90239 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00031 | 7767 | 9410 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00109 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00001 | 38176 | 39369 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 107745 | 108878 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00021 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00001 | 127506 | 128663 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00007 | 67552 | 68784 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00021 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00021 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00065 | 2243 | 2971 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00065 | 1051 | 1875 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00017 | 91674 | 92087 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00057 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00048 | 31344 | 31727 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00047 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00047 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00047 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00065 | 6472 | 7629 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00065 | 3334 | 6447 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00033 | 18401 | 19627 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00033 | 28256 | 29464 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00053 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00037 | 22336 | 23367 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00037 | 20285 | 22336 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00037 | 18822 | 20288 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00120 | 68 | 970 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00008 | 114189 | 114665 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00005 | 51374 | 53122 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00006 | 62062 | 63030 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00079 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00103 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00010 | 66737 | 68224 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 1959 | 3602 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00021 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00003 | 107745 | 108878 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00001 | 127506 | 128663 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00042 | 6419 | 7294 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00032 | 38461 | 40362 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00109 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00120 | 68 | 970 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00079 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00103 | 850 | 2055 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00079 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00079 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00042 | 6419 | 7294 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00003 | 107745 | 108878 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00079 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00109 | 289 | 1026 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00120 | 68 | 998 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00079 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00103 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00001 | 38176 | 39369 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00001 | 39392 | 42541 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00008 | 135351 | 138464 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00011 | 127888 | 129045 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00011 | 129057 | 132161 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00011 | 126827 | 127489 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00003 | 107745 | 108878 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00001 | 127506 | 128663 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00079 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00047 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00010 | 90602 | 91423 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00047 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00047 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00024 | 49210 | 50400 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00013 | 60628 | 61326 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00013 | 61323 | 62696 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15750 | 16382 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00128 | 61 | 984 | CTX | 0/0 | 98.0 | 98.3 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00079 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00004 | 90366 | 91538 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00004 | 91555 | 93093 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00012 | 43177 | 44367 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00021 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00004 | 89709 | 90239 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00031 | 7767 | 9410 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00109 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00021 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00065 | 2243 | 2971 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00065 | 1051 | 1875 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00017 | 91674 | 92087 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00057 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00048 | 31338 | 31727 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00048 | 30890 | 31324 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00007 | 67552 | 68784 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00047 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00047 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00047 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00065 | 6472 | 7629 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00065 | 3334 | 6447 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00033 | 18401 | 19627 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00033 | 28256 | 29464 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00045 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00045 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00025 | 31963 | 33336 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00053 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00037 | 22336 | 23367 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00037 | 20285 | 22336 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00037 | 18822 | 20288 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00120 | 68 | 998 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00008 | 114189 | 114665 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00005 | 51374 | 53122 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00032 | 38461 | 40362 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00021 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00006 | 62062 | 63030 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00002 | 19983 | 20852 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00026 | 2753 | 3076 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00079 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00103 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00006 | 1959 | 3602 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00117 | 2601 | 3461 | blaSHV-12_1 | 0/0 | 100 | 100.0 | KF976405 | blaSHV-12 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00072 | 18824 | 19306 | dfrA14_5 | 0/0 | 100 | 99.6 | DQ388123 | dfrA14 | Trimethoprim |
| contig00040 | 30290 | 31522 | mdf(A)_1 | 0/0 | 100 | 99.9 | Y08743 | mdf(A) |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00022 | 35950 | 39099 | acrB | 0/0 | 100.0 | 99.8 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 134904 | 138017 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00057 | 8641 | 9798 | acrE | 0/0 | 100.0 | 99.0 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00057 | 5525 | 8629 | acrF | 0/0 | 100.0 | 99.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00057 | 10197 | 10859 | acrS | 0/0 | 100.0 | 99.1 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 95858 | 96679 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00001 | 132646 | 133368 | baeR | 0/0 | 100.0 | 98.1 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00001 | 133365 | 134768 | baeS | 0/0 | 100.0 | 98.8 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00020 | 22373 | 23746 | cpxA | 0/0 | 100.0 | 98.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.8 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00072 | 18824 | 19306 | dfrA14 | 0/0 | 100.0 | 99.8 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00005 | 62310 | 63482 | emrA | 0/0 | 100.0 | 99.8 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00005 | 63499 | 65037 | emrB | 0/0 | 100.0 | 99.9 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00004 | 125401 | 126456 | emrK | 0/0 | 100.0 | 99.3 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00005 | 61653 | 62183 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00004 | 123863 | 125401 | emrY | 0/0 | 100.0 | 98.8 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00053 | 7690 | 9333 | eptA | 0/0 | 100.0 | 99.8 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00022 | 39122 | 40315 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00055 | 16878 | 18011 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.5 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00003 | 169461 | 170765 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 97.8 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00024 | 49342 | 50499 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00040 | 30290 | 31522 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00004 | 126980 | 127594 | evgA | 0/0 | 100.0 | 99.3 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00004 | 127599 | 131192 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00037 | 40035 | 40763 | gadW | 0/0 | 100.0 | 94.5 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00037 | 41131 | 41955 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00027 | 5179 | 5592 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00099 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 99.1 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00015 | 19337 | 19720 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 142381 | 143628 | mdtA | 0/0 | 100.0 | 99.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00001 | 139259 | 142381 | mdtB | 0/0 | 100.0 | 99.0 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00001 | 136181 | 139258 | mdtC | 0/0 | 100.0 | 99.5 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00037 | 35377 | 36534 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00037 | 36559 | 39672 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00008 | 84610 | 85836 | mdtG | 0/0 | 100.0 | 99.8 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00008 | 74771 | 75979 | mdtH | 0/0 | 100.0 | 97.8 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00071 | 262 | 1473 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00039 | 20077 | 21108 | mdtN | 0/0 | 100.0 | 99.9 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00039 | 18026 | 20077 | mdtO | 0/0 | 100.0 | 99.8 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00039 | 16563 | 18029 | mdtP | 0/0 | 100.0 | 98.2 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00003 | 113964 | 114440 | mphB | 0/0 | 100.0 | 99.4 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00006 | 51524 | 53272 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00007 | 106948 | 107916 | pmrF | 0/0 | 100.0 | 99.6 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00117 | 2601 | 3461 | SHV-134 | 0/0 | 100.0 | 99.9 | HM559945:0-861 | SHV-134 is an extended-spectrum beta-lactamase. | carbapenem, cephalosporin, penam |
| contig00002 | 71958 | 73445 | tolC | 0/0 | 100.0 | 99.7 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 194385 | 195551 | ugd | 0/0 | 100.0 | 96.2 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00007 | 47104 | 48747 | yojI | 0/0 | 100.0 | 99.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00003 | 169461 | 170765 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 97.8 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00055 | 16878 | 18011 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 98.5 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00024 | 49342 | 50499 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00117 | 2601 | 3461 | (Bla)blaSHV-12 | 0/0 | 100 | 100.0 | FJ685654:24-860 | (Bla)blaSHV-12 | NA |
| contig00014 | 19999 | 21900 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 99.5 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00072 | 18824 | 19297 | (Tmt)dfrA14 | 0/0 | 100 | 100.0 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00055 | 16878 | 18011 | blaEC | 0/0 | 100 | 100 | NG_047496.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00117 | 2601 | 3461 | blaSHV-12 | 0/0 | 100 | 100 | NG_050590.1 | class A extended-spectrum beta-lactamase SHV-12 | CEPHALOSPORIN |
| contig00072 | 18824 | 19297 | dfrA14 | 0/0 | 100 | 100 | NG_056035.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00022 | 39122 | 40315 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00022 | 35950 | 39099 | ACRB | 0/0 | 100.0 | 99.8 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00003 | 134904 | 138017 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00057 | 8641 | 9798 | ACRE | 0/0 | 100.0 | 99.0 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00057 | 5525 | 8629 | ACRF | 0/0 | 100.0 | 99.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00057 | 10197 | 10859 | ACRS | 0/0 | 100.0 | 99.1 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00024 | 49342 | 50499 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00001 | 155297 | 157149 | ASMA | 0/0 | 100.0 | 93.8 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00002 | 95858 | 96679 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00001 | 132646 | 133368 | BAER | 0/0 | 100.0 | 98.1 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00001 | 133365 | 134768 | BAES | 0/0 | 100.0 | 98.8 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 8223 | 9413 | BCR | 0/0 | 100.0 | 97.1 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00055 | 16878 | 18011 | BLAEC | 0/0 | 100.0 | 100.0 | MEG_1276 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00020 | 21678 | 22376 | CPXAR | 0/0 | 100.0 | 99.7 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00020 | 22373 | 23746 | CPXAR | 0/0 | 100.0 | 98.6 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.8 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00015 | 65608 | 66550 | CTX | 0/0 | 100.0 | 98.8 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00072 | 18824 | 19297 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00005 | 62310 | 63482 | EMRA | 0/0 | 100.0 | 99.8 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00005 | 63499 | 65037 | EMRB | 0/0 | 100.0 | 99.9 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00018 | 16827 | 18017 | EMRD | 0/0 | 100.0 | 99.8 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00004 | 125401 | 126564 | EMRK | 0/0 | 100.0 | 99.1 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00005 | 61653 | 62183 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00004 | 123863 | 125401 | EMRY | 0/0 | 100.0 | 98.9 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00053 | 7690 | 9333 | EPTA | 0/0 | 100.0 | 99.8 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00004 | 127599 | 131192 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00037 | 40035 | 40763 | GADW | 0/0 | 100.0 | 99.9 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00037 | 41131 | 41955 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00027 | 5179 | 5592 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00099 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 99.1 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00015 | 19337 | 19726 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00015 | 19740 | 20174 | MARR | 0/0 | 100.0 | 97.5 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00040 | 30290 | 31522 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00001 | 142381 | 143628 | MDTA | 0/0 | 100.0 | 99.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00001 | 139259 | 142381 | MDTB | 0/0 | 100.0 | 99.0 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00001 | 136181 | 139258 | MDTC | 0/0 | 100.0 | 99.5 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00037 | 35377 | 36534 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00037 | 36559 | 39672 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00008 | 84610 | 85836 | MDTG | 0/0 | 100.0 | 99.8 | MEG_3754 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00008 | 74771 | 75979 | MDTH | 0/0 | 100.0 | 97.8 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00048 | 309 | 638 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00023 | 12649 | 14022 | MDTK | 0/0 | 100.0 | 99.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00071 | 262 | 1473 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00039 | 20077 | 21108 | MDTN | 0/0 | 100.0 | 99.9 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00039 | 18026 | 20077 | MDTO | 0/0 | 100.0 | 99.8 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00039 | 16563 | 18029 | MDTP | 0/0 | 100.0 | 98.2 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00003 | 113964 | 114440 | MPHB | 0/0 | 100.0 | 99.4 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00006 | 51524 | 53272 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00014 | 19999 | 21900 | PBP2 | 0/0 | 100.0 | 99.5 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00003 | 169461 | 170765 | PBP4B | 0/0 | 100.0 | 97.8 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00007 | 106948 | 107916 | PMRF | 0/0 | 100.0 | 99.6 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00060 | 10835 | 11704 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00117 | 2504 | 3507 | SHV | 0/0 | 99.7 | 98.9 | MEG_6428 | Drugs:betalactams:Class_A_betalactamases:SHV | NA |
| contig00104 | 1347 | 1670 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00001 | 194385 | 195551 | UGD | 0/0 | 100.0 | 96.2 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00007 | 47104 | 48747 | YOGI | 0/0 | 100.0 | 99.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00080 | 35 | 895 | aac(3)-IId_1 | 0/0 | 100.0 | 99.9 | EU022314 | aac(3)-IId | Gentamicin, Tobramycin |
| contig00072 | 3038 | 3826 | aadA5_1 | 0/0 | 100.0 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00081 | 1610 | 2412 | aph(3’’)-Ib_2 | 0/0 | 99.9 | 100.0 | AF024602 | aph(3’’)-Ib | Streptomycin |
| contig00081 | 774 | 1610 | aph(6)-Id_1 | 0/0 | 100.0 | 99.9 | M28829 | aph(6)-Id | Streptomycin |
| contig00032 | 28202 | 29077 | blaCTX-M-14_1 | 0/0 | 100.0 | 100.0 | AF252622 | blaCTX-M-14 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00082 | 1835 | 2695 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00072 | 3957 | 4430 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00014 | 32368 | 33600 | mdf(A)_1 | 0/0 | 100.0 | 98.1 | Y08743 | mdf(A) | |
| contig00095 | 69 | 990 | mph(A)_2 | 1/1 | 100.0 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00072 | 1652 | 2518 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00078 | 704 | 1519 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00080 | 35 | 895 | AAC(3)-IId | 0/0 | 100.0 | 99.9 | EU022314.1:0-861 | AAC(3)-IId is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00072 | 3038 | 3826 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00043 | 12982 | 16131 | acrB | 0/0 | 100.0 | 99.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 134559 | 137672 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00017 | 83805 | 84962 | acrE | 0/0 | 100.0 | 98.4 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00017 | 84974 | 88078 | acrF | 0/0 | 100.0 | 97.8 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00017 | 82744 | 83406 | acrS | 0/0 | 100.0 | 98.9 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00081 | 1610 | 2413 | APH(3’’)-Ib | 0/0 | 100.0 | 99.9 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00081 | 774 | 1610 | APH(6)-Id | 0/0 | 100.0 | 99.8 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00002 | 115744 | 116563 | bacA | 0/0 | 99.8 | 96.2 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00025 | 10839 | 11560 | baeR | 0/0 | 99.9 | 98.1 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00025 | 9439 | 10842 | baeS | 0/0 | 100.0 | 96.4 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00018 | 22716 | 24089 | cpxA | 0/0 | 100.0 | 98.6 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15391 | 16023 | CRP | 0/0 | 100.0 | 99.0 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00032 | 28202 | 29077 | CTX-M-14 | 0/0 | 100.0 | 100.0 | AF252622:1740-2616 | CTX-M-14 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00072 | 3957 | 4430 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00026 | 16391 | 17563 | emrA | 0/0 | 100.0 | 98.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00026 | 17580 | 19118 | emrB | 0/0 | 100.0 | 98.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00012 | 85378 | 86433 | emrK | 0/0 | 100.0 | 97.8 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00026 | 15734 | 16264 | emrR | 0/0 | 100.0 | 99.4 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00012 | 83840 | 85378 | emrY | 0/0 | 100.0 | 97.4 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00004 | 80809 | 82452 | eptA | 0/0 | 100.0 | 98.2 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00043 | 16154 | 17347 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.2 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 124371 | 125504 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.7 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00042 | 27940 | 29244 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 96.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00007 | 24730 | 25887 | Escherichia_coli_ampH | 0/0 | 100.0 | 96.8 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00014 | 32368 | 33600 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.6 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00012 | 86957 | 87571 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00012 | 87576 | 91169 | evgS | 0/0 | 100.0 | 96.8 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00028 | 54226 | 54954 | gadW | 0/0 | 100.0 | 95.6 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00028 | 55323 | 56147 | gadX | 0/0 | 100.0 | 94.3 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00047 | 28158 | 28571 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00011 | 7853 | 8530 | kdpE | 0/0 | 100.0 | 95.4 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00001 | 282280 | 282663 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00025 | 579 | 1826 | mdtA | 0/0 | 100.0 | 97.4 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00025 | 1826 | 4948 | mdtB | 0/0 | 100.0 | 96.7 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00025 | 4949 | 8026 | mdtC | 0/0 | 100.0 | 97.1 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00028 | 49568 | 50725 | mdtE | 0/0 | 100.0 | 98.8 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00028 | 50750 | 53863 | mdtF | 0/0 | 100.0 | 98.5 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00016 | 2669 | 3895 | mdtG | 0/0 | 100.0 | 98.5 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00023 | 69659 | 70867 | mdtH | 0/0 | 100.0 | 97.8 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00004 | 57173 | 58204 | mdtN | 0/0 | 100.0 | 96.4 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00004 | 55122 | 57173 | mdtO | 0/0 | 100.0 | 96.3 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00004 | 53659 | 55125 | mdtP | 0/0 | 100.0 | 97.5 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00095 | 69 | 974 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00008 | 113378 | 113852 | mphB | 0/0 | 99.6 | 96.6 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00034 | 6455 | 8203 | msbA | 0/0 | 100.0 | 99.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00005 | 156039 | 157007 | pmrF | 0/0 | 100.0 | 98.1 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00072 | 1652 | 2491 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00078 | 704 | 1519 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00082 | 1835 | 2695 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00002 | 137275 | 138762 | tolC | 0/0 | 100.0 | 98.5 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 92900 | 94543 | yojI | 0/0 | 100.0 | 97.5 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00080 | 35 | 895 | (AGly)aac3-IId | 0/0 | 100 | 99.9 | EU022314:1-861 | (AGly)aac3-IId | NA |
| contig00072 | 3038 | 3826 | (AGly)aadA5 | 0/0 | 100 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00081 | 1610 | 2413 | (AGly)strA | 0/0 | 100 | 100.0 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00081 | 774 | 1610 | (AGly)strB | 0/0 | 100 | 99.9 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00042 | 27940 | 29244 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 96.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00004 | 124371 | 125504 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.7 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00007 | 24730 | 25887 | (Bla)ampH_Ecoli | 0/0 | 100 | 96.8 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00032 | 28202 | 29077 | (Bla)blaCTX-M-14 | 0/0 | 100 | 100.0 | AF252622:1741-2616 | (Bla)blaCTX-M-14 | NA |
| contig00082 | 1835 | 2695 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00011 | 50375 | 52276 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 99.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00095 | 69 | 974 | (MLS)mph(A) | 0/0 | 100 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00072 | 1652 | 2491 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00078 | 704 | 1519 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00072 | 3957 | 4430 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00080 | 35 | 895 | aac(3)-IId | 0/0 | 100 | 100.0 | NG_047251.1 | aminoglycoside N-acetyltransferase AAC(3)-IId | GENTAMICIN |
| contig00072 | 3038 | 3826 | aadA5 | 0/0 | 100 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00081 | 1610 | 2437 | aph(3’’)-Ib | 0/0 | 100 | 99.9 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00081 | 774 | 1610 | aph(6)-Id | 0/0 | 100 | 99.9 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00032 | 28202 | 29077 | blaCTX-M-14 | 0/0 | 100 | 100.0 | NG_048929.1 | class A extended-spectrum beta-lactamase CTX-M-14 | CEPHALOSPORIN |
| contig00004 | 124371 | 125504 | blaEC-8 | 0/0 | 100 | 98.2 | NG_049086.1 | cephalosporin-hydrolyzing class C beta-lactamase EC-8 | CEPHALOSPORIN |
| contig00082 | 1835 | 2695 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00072 | 3957 | 4430 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00095 | 69 | 990 | mph(A) | 1/1 | 100 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00072 | 1652 | 2491 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00078 | 704 | 1519 | sul2 | 0/0 | 100 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00080 | 35 | 895 | AAC3 | 0/0 | 100.0 | 100.0 | MEG_64 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00043 | 16154 | 17347 | ACRA | 0/0 | 100.0 | 99.2 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00043 | 12982 | 16131 | ACRB | 0/0 | 100.0 | 99.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00008 | 134559 | 137672 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00017 | 83805 | 84962 | ACRE | 0/0 | 100.0 | 98.4 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00017 | 84974 | 88078 | ACRF | 0/0 | 100.0 | 97.8 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00017 | 82744 | 83406 | ACRS | 0/0 | 100.0 | 98.9 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00007 | 24730 | 25887 | AMPH | 0/0 | 100.0 | 96.8 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00072 | 3038 | 3826 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00081 | 1610 | 2437 | APH3-DPRIME | 0/0 | 100.0 | 99.9 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00081 | 774 | 1610 | APH6 | 0/0 | 100.0 | 99.9 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00033 | 11265 | 13117 | ASMA | 0/0 | 100.0 | 98.3 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00002 | 115744 | 116563 | BACA | 0/0 | 99.8 | 96.7 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00025 | 10839 | 11560 | BAER | 0/0 | 99.9 | 98.1 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00025 | 9439 | 10842 | BAES | 0/0 | 100.0 | 96.4 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00005 | 66439 | 67629 | BCR | 0/0 | 100.0 | 97.5 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00004 | 124371 | 125504 | BLAEC | 0/0 | 100.0 | 98.2 | MEG_1278 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00018 | 22021 | 22719 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00018 | 22716 | 24089 | CPXAR | 0/0 | 100.0 | 98.8 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15391 | 16023 | CRP | 0/0 | 100.0 | 99.0 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00032 | 28196 | 29099 | CTX | 0/0 | 100.0 | 99.9 | MEG_2401 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00072 | 3957 | 4430 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00026 | 16391 | 17563 | EMRA | 0/0 | 100.0 | 98.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00026 | 17580 | 19118 | EMRB | 0/0 | 100.0 | 98.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00015 | 87427 | 88617 | EMRD | 0/0 | 100.0 | 97.7 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00012 | 85378 | 86541 | EMRK | 0/0 | 100.0 | 98.0 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00026 | 15734 | 16264 | EMRR | 0/0 | 100.0 | 99.4 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00012 | 83840 | 85378 | EMRY | 0/0 | 100.0 | 97.5 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00004 | 80809 | 82452 | EPTA | 0/0 | 100.0 | 98.2 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00012 | 87576 | 91169 | EVGS | 0/0 | 100.0 | 97.3 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00028 | 54226 | 54954 | GADW | 0/0 | 100.0 | 97.8 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00028 | 55323 | 56147 | GADX | 0/0 | 100.0 | 94.3 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00047 | 28158 | 28571 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00011 | 7853 | 8530 | KDPE | 0/0 | 100.0 | 95.4 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00001 | 282280 | 282669 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00001 | 282684 | 283118 | MARR | 0/0 | 100.0 | 97.9 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00014 | 32368 | 33600 | MDFA | 0/0 | 100.0 | 98.2 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00025 | 579 | 1826 | MDTA | 0/0 | 100.0 | 97.4 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00025 | 1826 | 4948 | MDTB | 0/0 | 100.0 | 96.7 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00025 | 4949 | 8026 | MDTC | 0/0 | 100.0 | 97.1 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00028 | 49568 | 50725 | MDTE | 0/0 | 100.0 | 98.8 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00028 | 50750 | 53863 | MDTF | 0/0 | 100.0 | 98.5 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00016 | 2669 | 3895 | MDTG | 0/0 | 100.0 | 98.7 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00023 | 69659 | 70867 | MDTH | 0/0 | 100.0 | 97.8 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00001 | 243783 | 244112 | MDTI | 0/0 | 100.0 | 99.7 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00001 | 243431 | 243796 | MDTJ | 0/0 | 100.0 | 98.1 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00001 | 172381 | 173753 | MDTK | 0/0 | 99.9 | 98.2 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00004 | 57173 | 58204 | MDTN | 0/0 | 100.0 | 96.4 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00004 | 55122 | 57173 | MDTO | 0/0 | 100.0 | 96.3 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00004 | 53659 | 55125 | MDTP | 0/0 | 100.0 | 97.5 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00095 | 69 | 990 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00008 | 113378 | 113852 | MPHB | 0/0 | 99.6 | 96.6 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00034 | 6455 | 8203 | MSBA | 0/0 | 100.0 | 99.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00011 | 50375 | 52276 | PBP2 | 0/0 | 100.0 | 99.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00042 | 27940 | 29244 | PBP4B | 0/0 | 100.0 | 96.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00005 | 156039 | 157007 | PMRF | 0/0 | 100.0 | 98.1 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00003 | 232638 | 233507 | ROBA | 0/0 | 100.0 | 99.5 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00004 | 31693 | 32015 | SOXS | 0/0 | 99.7 | 97.5 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00072 | 1525 | 2492 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00078 | 704 | 1519 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00082 | 1817 | 3062 | TEM | 0/0 | 98.3 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00005 | 92900 | 94543 | YOGI | 0/0 | 100.0 | 97.5 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00068 | 391 | 1266 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00091 | 91 | 732 | catA2_1 | 0/0 | 100.0 | 96.0 | X53796 | catA2 | Chloramphenicol |
| contig00066 | 7607 | 7993 | fosA7_1 | 0/0 | 91.5 | 93.5 | LAPJ01000014 | fosA7 | Fosfomycin |
| contig00030 | 29805 | 31037 | mdf(A)_1 | 0/0 | 100.0 | 98.4 | Y08743 | mdf(A) | |
| contig00072 | 208 | 864 | qnrS1_1 | 0/0 | 100.0 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| contig00062 | 754 | 2000 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00007 | 143948 | 147097 | acrB | 0/0 | 100.0 | 99.2 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 135915 | 139028 | acrD | 0/0 | 100.0 | 98.6 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00005 | 203227 | 204384 | acrE | 0/0 | 100.0 | 98.8 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00005 | 204396 | 207500 | acrF | 0/0 | 100.0 | 99.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00005 | 202166 | 202828 | acrS | 0/0 | 100.0 | 99.1 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00013 | 123262 | 124081 | bacA | 0/0 | 99.8 | 98.5 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00053 | 10682 | 11404 | baeR | 0/0 | 100.0 | 99.5 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00053 | 9282 | 10685 | baeS | 0/0 | 100.0 | 96.6 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00091 | 91 | 732 | catII_from_Escherichia_coli_K-12 | 0/0 | 100.0 | 96.0 | X53796.1:186-828 | catII is a chloramphenicol acetyltransferase. This particular catII is found in E.coli K-12. Confers resistance to chloramphenicol. | phenicol |
| contig00020 | 22613 | 23986 | cpxA | 0/0 | 100.0 | 98.5 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00002 | 267478 | 268110 | CRP | 0/0 | 100.0 | 99.0 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00068 | 391 | 1266 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00051 | 17471 | 18643 | emrA | 0/0 | 100.0 | 98.1 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00051 | 18660 | 20198 | emrB | 0/0 | 100.0 | 99.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00027 | 9379 | 10434 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00051 | 16814 | 17344 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00027 | 7841 | 9379 | emrY | 0/0 | 100.0 | 98.2 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00001 | 167186 | 168829 | eptA | 0/0 | 100.0 | 99.3 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00007 | 147120 | 148313 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.8 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 123829 | 124962 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.7 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00008 | 170346 | 171650 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00007 | 55729 | 56886 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.7 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00030 | 29805 | 31037 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.8 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00027 | 10958 | 11572 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00027 | 11577 | 15170 | evgS | 0/0 | 100.0 | 99.1 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00066 | 7607 | 7993 | FosA7 | 0/0 | 91.5 | 93.5 | LAPJ01000014.1:36822-37245 | fosA7 is an enzyme that confers resistance to fosfomycin in Escherichia coli by breaking the epoxide ring of the molecule. | fosfomycin |
| contig00002 | 97574 | 98302 | gadW | 0/0 | 100.0 | 94.4 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00002 | 96382 | 97206 | gadX | 0/0 | 100.0 | 97.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00011 | 148523 | 148936 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00015 | 8002 | 8674 | kdpE | 0/0 | 99.3 | 97.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00016 | 97329 | 97712 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00053 | 422 | 1669 | mdtA | 0/0 | 100.0 | 97.6 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00053 | 1669 | 4791 | mdtB | 0/0 | 100.0 | 98.3 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00053 | 4792 | 7869 | mdtC | 0/0 | 100.0 | 98.1 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00002 | 101803 | 102960 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00002 | 98665 | 101778 | mdtF | 0/0 | 100.0 | 98.6 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00014 | 125708 | 126934 | mdtG | 0/0 | 100.0 | 99.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00014 | 115869 | 117077 | mdtH | 0/0 | 100.0 | 98.5 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00010 | 131603 | 132835 | mdtM | 0/0 | 100.0 | 96.0 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00001 | 191492 | 192523 | mdtN | 0/0 | 100.0 | 98.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00001 | 192523 | 194574 | mdtO | 0/0 | 100.0 | 98.8 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00001 | 194571 | 196037 | mdtP | 0/0 | 100.0 | 98.2 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00008 | 113958 | 114432 | mphB | 0/0 | 99.6 | 97.5 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00004 | 86754 | 88502 | msbA | 0/0 | 100.0 | 99.3 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00003 | 124897 | 125865 | pmrF | 0/0 | 100.0 | 99.5 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00072 | 208 | 864 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00089 | 1043 | 1405 | ramA | 0/0 | 96.8 | 90.6 | JQ727668:0-375 | RamA (resistance antibiotic multiple) is a positive regulator of AcrAB-TolC and leads to high level multidrug resistance in Klebsiella pneumoniae Salmonella enterica and Enterobacter aerugenes increasing the expression of both the mar operon as well as AcrAB. RamA also decreases OmpF expression. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00062 | 754 | 2000 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00013 | 99416 | 100903 | tolC | 0/0 | 100.0 | 98.5 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 76214 | 77857 | yojI | 0/0 | 100.0 | 99.2 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00008 | 170346 | 171650 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 98.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00001 | 123829 | 124962 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 97.7 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00007 | 55729 | 56886 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 98.7 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00068 | 391 | 1266 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00015 | 60462 | 62363 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 99.4 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00066 | 7607 | 7993 | (Fcyn)FosA7 | 0/0 | 91.5 | 93.5 | LAPJ01000014:36823-37245 | (Fcyn)FosA7 | NA |
| contig00072 | 208 | 864 | (Flq)qnr-S1 | 0/0 | 100.0 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| contig00091 | 91 | 732 | (Phe)catA2 | 0/0 | 100.0 | 96.0 | X53796:187-903 | (Phe)catA2 | NA |
| contig00062 | 754 | 2028 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00062 | 73 | 723 | (Tet)tetR | 0/0 | 100.0 | 100.0 | HF545434:53576-54226 | (Tet)tetR | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00068 | 391 | 1266 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00001 | 123829 | 124962 | blaEC-18 | 0/0 | 100.0 | 99.2 | NG_049083.1 | class C extended-spectrum beta-lactamase EC-18 | CEPHALOSPORIN |
| contig00091 | 91 | 732 | catA2 | 0/0 | 100.0 | 99.8 | NG_047596.1 | type A-2 chloramphenicol O-acetyltransferase CatII | CHLORAMPHENICOL |
| contig00066 | 7607 | 7993 | fosA7.5 | 0/0 | 91.5 | 100.0 | NG_067231.1 | fosfomycin resistance glutathione transferase FosA7.5 | FOSFOMYCIN |
| contig00072 | 208 | 864 | qnrS1 | 0/0 | 100.0 | 100.0 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| contig00062 | 829 | 2028 | tet(A) | 0/0 | 100.0 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00007 | 147120 | 148313 | ACRA | 0/0 | 100.0 | 99.8 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00007 | 143948 | 147097 | ACRB | 0/0 | 100.0 | 99.2 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00008 | 135915 | 139028 | ACRD | 0/0 | 100.0 | 98.6 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00005 | 203227 | 204384 | ACRE | 0/0 | 100.0 | 98.8 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00005 | 204396 | 207500 | ACRF | 0/0 | 100.0 | 99.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00005 | 202166 | 202828 | ACRS | 0/0 | 100.0 | 99.1 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00007 | 55729 | 56886 | AMPH | 0/0 | 100.0 | 98.7 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00009 | 6961 | 8813 | ASMA | 0/0 | 100.0 | 98.2 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00013 | 123262 | 124081 | BACA | 0/0 | 99.8 | 98.8 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00053 | 10682 | 11404 | BAER | 0/0 | 100.0 | 99.5 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00053 | 9282 | 10685 | BAES | 0/0 | 100.0 | 96.6 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00003 | 49755 | 50945 | BCR | 0/0 | 100.0 | 98.1 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00001 | 123829 | 124962 | BLAEC | 0/0 | 100.0 | 99.2 | MEG_1279 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00091 | 91 | 732 | CATA | 0/0 | 100.0 | 99.8 | MEG_1568 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00020 | 21918 | 22616 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00020 | 22613 | 23986 | CPXAR | 0/0 | 100.0 | 99.1 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00002 | 267478 | 268110 | CRP | 0/0 | 100.0 | 99.0 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00051 | 17471 | 18643 | EMRA | 0/0 | 100.0 | 98.1 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00051 | 18660 | 20198 | EMRB | 0/0 | 100.0 | 99.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00006 | 104253 | 105443 | EMRD | 0/0 | 100.0 | 99.9 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00027 | 9379 | 10542 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00051 | 16814 | 17344 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00027 | 7841 | 9379 | EMRY | 0/0 | 100.0 | 98.3 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00001 | 167186 | 168829 | EPTA | 0/0 | 100.0 | 99.3 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00027 | 11577 | 15170 | EVGS | 0/0 | 100.0 | 99.1 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00066 | 7607 | 7993 | FOSA | 0/0 | 91.5 | 93.5 | MEG_2988 | Drugs:Fosfomycin:Fosfomycin_thiol_transferases:FOSA | NA |
| contig00002 | 97574 | 98302 | GADW | 0/0 | 100.0 | 98.6 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00002 | 96382 | 97206 | GADX | 0/0 | 100.0 | 97.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00011 | 148523 | 148936 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00015 | 8002 | 8674 | KDPE | 0/0 | 99.3 | 97.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00016 | 97323 | 97712 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00016 | 96875 | 97309 | MARR | 0/0 | 100.0 | 97.7 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00030 | 29805 | 31037 | MDFA | 0/0 | 100.0 | 98.5 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00053 | 422 | 1669 | MDTA | 0/0 | 100.0 | 97.6 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00053 | 1669 | 4791 | MDTB | 0/0 | 100.0 | 98.3 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00053 | 4792 | 7869 | MDTC | 0/0 | 100.0 | 98.1 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00002 | 101803 | 102960 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00002 | 98665 | 101778 | MDTF | 0/0 | 100.0 | 98.6 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00014 | 125708 | 126934 | MDTG | 0/0 | 100.0 | 99.5 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00014 | 115869 | 117077 | MDTH | 0/0 | 100.0 | 98.5 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00023 | 32064 | 32393 | MDTI | 0/0 | 100.0 | 99.4 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00023 | 32380 | 32745 | MDTJ | 0/0 | 100.0 | 99.7 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00037 | 1343 | 2716 | MDTK | 0/0 | 100.0 | 99.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00010 | 131603 | 132835 | MDTM | 0/0 | 100.0 | 96.0 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00001 | 191492 | 192523 | MDTN | 0/0 | 100.0 | 98.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00001 | 192523 | 194574 | MDTO | 0/0 | 100.0 | 98.8 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00001 | 194571 | 196037 | MDTP | 0/0 | 100.0 | 98.2 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00008 | 113958 | 114432 | MPHB | 0/0 | 99.6 | 97.5 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00004 | 86754 | 88502 | MSBA | 0/0 | 100.0 | 99.3 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00015 | 60462 | 62363 | PBP2 | 0/0 | 100.0 | 99.4 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00008 | 170346 | 171650 | PBP4B | 0/0 | 100.0 | 98.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00003 | 124897 | 125865 | PMRF | 0/0 | 100.0 | 99.5 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00072 | 208 | 864 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00089 | 1043 | 1405 | RAMA | 0/0 | 96.8 | 90.6 | MEG_6044 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:RAMA | NA |
| contig00010 | 67934 | 68803 | ROBA | 0/0 | 100.0 | 99.2 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00001 | 217653 | 217976 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00062 | 754 | 2028 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00003 | 76214 | 77857 | YOGI | 0/0 | 100.0 | 99.2 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00111 | 1696 | 2556 | aac(3)-IIa_1 | 0/0 | 100.0 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00113 | 1540 | 2139 | aac(6’)-Ib-cr_1 | 0/0 | 100.0 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00082 | 1308 | 2096 | aadA5_1 | 0/0 | 100.0 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00088 | 3970 | 4773 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00088 | 3134 | 3970 | aph(6)-Id_1 | 0/0 | 100.0 | 99.9 | M28829 | aph(6)-Id | Streptomycin |
| contig00089 | 2404 | 3279 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00113 | 579 | 1409 | blaOXA-1_1 | 0/0 | 100.0 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00082 | 704 | 1177 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00015 | 32470 | 33702 | mdf(A)_1 | 0/0 | 100.0 | 97.9 | Y08743 | mdf(A) | |
| contig00133 | 69 | 990 | mph(A)_2 | 1/1 | 100.0 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00082 | 2616 | 3482 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00088 | 4834 | 5649 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00088 | 909 | 2155 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00111 | 1696 | 2556 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00113 | 1540 | 2139 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00082 | 1308 | 2096 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00025 | 54140 | 57289 | acrB | 0/0 | 100.0 | 99.1 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 146537 | 149650 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00005 | 163425 | 164582 | acrE | 0/0 | 100.0 | 98.5 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00005 | 164594 | 167698 | acrF | 0/0 | 100.0 | 97.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00005 | 162364 | 163026 | acrS | 0/0 | 100.0 | 98.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00088 | 3970 | 4773 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00088 | 3134 | 3970 | APH(6)-Id | 0/0 | 100.0 | 99.8 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00008 | 114242 | 115061 | bacA | 0/0 | 99.8 | 98.5 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00001 | 99748 | 100469 | baeR | 0/0 | 99.9 | 98.2 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00001 | 98348 | 99751 | baeS | 0/0 | 100.0 | 97.7 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00020 | 22913 | 24286 | cpxA | 0/0 | 100.0 | 98.2 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00018 | 15385 | 16017 | CRP | 0/0 | 100.0 | 98.9 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00089 | 2404 | 3279 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00082 | 704 | 1177 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00009 | 58704 | 59876 | emrA | 0/0 | 100.0 | 98.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00009 | 59893 | 61431 | emrB | 0/0 | 100.0 | 98.6 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00001 | 414438 | 415493 | emrK | 0/0 | 100.0 | 98.0 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00009 | 58047 | 58577 | emrR | 0/0 | 100.0 | 99.4 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00001 | 412900 | 414438 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00011 | 100959 | 102602 | eptA | 0/0 | 100.0 | 97.8 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00025 | 57312 | 58505 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.3 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00014 | 101671 | 102804 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00074 | 8301 | 9599 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 99.5 | 96.1 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00016 | 14787 | 15944 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00002 | 20788 | 21120 | Escherichia_coli_emrE | 0/0 | 100.0 | 91.9 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00015 | 32470 | 33702 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.3 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00001 | 416017 | 416631 | evgA | 0/0 | 100.0 | 99.2 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00001 | 416636 | 420229 | evgS | 0/0 | 100.0 | 96.8 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00012 | 56718 | 57446 | gadW | 0/0 | 100.0 | 95.5 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00012 | 55525 | 56349 | gadX | 0/0 | 100.0 | 94.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00050 | 21114 | 21527 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00056 | 7859 | 8536 | kdpE | 0/0 | 100.0 | 97.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00017 | 76818 | 77201 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 89488 | 90735 | mdtA | 0/0 | 100.0 | 96.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00001 | 90735 | 93857 | mdtB | 0/0 | 100.0 | 96.8 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00001 | 93858 | 96935 | mdtC | 0/0 | 100.0 | 97.1 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00012 | 60947 | 62104 | mdtE | 0/0 | 100.0 | 98.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00012 | 57809 | 60922 | mdtF | 0/0 | 100.0 | 98.4 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00021 | 38513 | 39739 | mdtG | 0/0 | 100.0 | 98.2 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00021 | 28674 | 29882 | mdtH | 0/0 | 100.0 | 98.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00011 | 77310 | 78341 | mdtN | 0/0 | 100.0 | 96.4 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00011 | 75259 | 77310 | mdtO | 0/0 | 100.0 | 97.4 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00011 | 73796 | 75262 | mdtP | 0/0 | 100.0 | 96.7 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00133 | 69 | 974 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00004 | 125356 | 125830 | mphB | 0/0 | 99.6 | 96.2 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00010 | 50246 | 51994 | msbA | 0/0 | 100.0 | 98.7 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00113 | 579 | 1409 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00001 | 299927 | 300895 | pmrF | 0/0 | 100.0 | 98.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00082 | 2643 | 3482 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00088 | 4834 | 5649 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00088 | 909 | 2155 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00008 | 90475 | 91962 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 33341 | 34507 | ugd | 0/0 | 100.0 | 96.9 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00001 | 238174 | 239817 | yojI | 0/0 | 100.0 | 98.3 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00111 | 1696 | 2556 | (AGly)aac3-IIa | 0/0 | 100.0 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00082 | 1308 | 2096 | (AGly)aadA5 | 0/0 | 100.0 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00088 | 3970 | 4773 | (AGly)strA | 0/0 | 100.0 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00088 | 3134 | 3970 | (AGly)strB | 0/0 | 100.0 | 99.9 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00074 | 8301 | 9599 | (Bla)AmpC1_Ecoli | 0/0 | 99.5 | 96.1 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00014 | 101671 | 102804 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 98.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00016 | 14787 | 15944 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 98.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00089 | 2404 | 3279 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00113 | 579 | 1409 | (Bla)blaOXA-1 | 0/0 | 100.0 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00006 | 28477 | 30378 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 99.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00133 | 69 | 974 | (MLS)mph(A) | 0/0 | 100.0 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00082 | 2643 | 3482 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00088 | 4834 | 5649 | (Sul)sul2 | 0/0 | 100.0 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00088 | 881 | 2155 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00088 | 2186 | 2812 | (Tet)tetR | 1/24 | 96.3 | 96.3 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00082 | 704 | 1177 | (Tmt)dfrA17 | 0/0 | 100.0 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00111 | 1696 | 2556 | aac(3)-IIe | 0/0 | 100 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00113 | 1540 | 2094 | aac(6’)-Ib-D181Y | 0/0 | 100 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00082 | 1308 | 2096 | aadA5 | 0/0 | 100 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00088 | 3970 | 4797 | aph(3’’)-Ib | 0/0 | 100 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00088 | 3134 | 3970 | aph(6)-Id | 0/0 | 100 | 100.0 | NG_047466.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00089 | 2404 | 3279 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00014 | 101671 | 102804 | blaEC-8 | 0/0 | 100 | 98.7 | NG_049086.1 | cephalosporin-hydrolyzing class C beta-lactamase EC-8 | CEPHALOSPORIN |
| contig00113 | 579 | 1409 | blaOXA-1 | 0/0 | 100 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00082 | 704 | 1177 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00133 | 69 | 990 | mph(A) | 1/1 | 100 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00082 | 2643 | 3482 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00088 | 4834 | 5649 | sul2 | 0/0 | 100 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00088 | 881 | 2080 | tet(A) | 0/0 | 100 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00111 | 1696 | 2556 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00025 | 57312 | 58505 | ACRA | 0/0 | 100.0 | 99.3 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00025 | 54140 | 57289 | ACRB | 0/0 | 100.0 | 99.1 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00004 | 146537 | 149650 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00005 | 163425 | 164582 | ACRE | 0/0 | 100.0 | 98.5 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00005 | 164594 | 167698 | ACRF | 0/0 | 100.0 | 97.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00005 | 162364 | 163026 | ACRS | 0/0 | 100.0 | 98.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00016 | 14787 | 15944 | AMPH | 0/0 | 100.0 | 98.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00082 | 1308 | 2096 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00088 | 3970 | 4797 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00088 | 3134 | 3970 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1084 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00001 | 74974 | 76826 | ASMA | 0/0 | 100.0 | 98.2 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00008 | 114242 | 115061 | BACA | 0/0 | 99.8 | 98.8 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00001 | 99748 | 100469 | BAER | 0/0 | 99.9 | 98.2 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00001 | 98348 | 99751 | BAES | 0/0 | 100.0 | 97.7 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 211714 | 212904 | BCR | 0/0 | 100.0 | 96.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00014 | 101671 | 102804 | BLAEC | 0/0 | 100.0 | 98.7 | MEG_1278 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00020 | 22218 | 22916 | CPXAR | 0/0 | 100.0 | 99.3 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00020 | 22913 | 24286 | CPXAR | 0/0 | 100.0 | 98.2 | MEG_2119 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00018 | 15385 | 16017 | CRP | 0/0 | 100.0 | 98.9 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00082 | 704 | 1177 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00009 | 58704 | 59876 | EMRA | 0/0 | 100.0 | 98.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00009 | 59893 | 61431 | EMRB | 0/0 | 100.0 | 98.6 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00013 | 24887 | 26077 | EMRD | 0/0 | 100.0 | 97.6 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00001 | 414438 | 415601 | EMRK | 0/0 | 100.0 | 98.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00009 | 58047 | 58577 | EMRR | 0/0 | 100.0 | 99.4 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00001 | 412900 | 414438 | EMRY | 0/0 | 100.0 | 97.7 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00011 | 100959 | 102602 | EPTA | 0/0 | 100.0 | 97.8 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00001 | 416636 | 420229 | EVGS | 0/0 | 100.0 | 97.2 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00012 | 56718 | 57446 | GADW | 0/0 | 100.0 | 97.4 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00012 | 55525 | 56349 | GADX | 0/0 | 100.0 | 94.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00050 | 21114 | 21527 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00056 | 7859 | 8536 | KDPE | 0/0 | 100.0 | 97.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00017 | 76812 | 77201 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00017 | 76363 | 76797 | MARR | 0/0 | 100.0 | 97.9 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00015 | 32470 | 33702 | MDFA | 0/0 | 100.0 | 98.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00001 | 89488 | 90735 | MDTA | 0/0 | 100.0 | 96.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00001 | 90735 | 93857 | MDTB | 0/0 | 100.0 | 96.8 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00001 | 93858 | 96935 | MDTC | 0/0 | 100.0 | 97.1 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00012 | 60947 | 62104 | MDTE | 0/0 | 100.0 | 98.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00012 | 57809 | 60922 | MDTF | 0/0 | 100.0 | 98.4 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00021 | 38513 | 39739 | MDTG | 0/0 | 100.0 | 98.8 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00021 | 28674 | 29882 | MDTH | 0/0 | 100.0 | 98.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00027 | 51282 | 51611 | MDTI | 0/0 | 100.0 | 99.4 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00027 | 50930 | 51295 | MDTJ | 0/0 | 100.0 | 98.1 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00002 | 286055 | 287427 | MDTK | 0/0 | 99.9 | 97.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00011 | 77310 | 78341 | MDTN | 0/0 | 100.0 | 96.4 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00011 | 75259 | 77310 | MDTO | 0/0 | 100.0 | 97.4 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00011 | 73796 | 75262 | MDTP | 0/0 | 100.0 | 96.7 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00133 | 69 | 990 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00004 | 125356 | 125830 | MPHB | 0/0 | 99.6 | 96.2 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00010 | 50246 | 51994 | MSBA | 0/0 | 100.0 | 98.7 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00002 | 20788 | 21120 | MVRC | 0/0 | 100.0 | 91.9 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00113 | 579 | 1409 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00006 | 28477 | 30378 | PBP2 | 0/0 | 100.0 | 99.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00074 | 8301 | 9599 | PBP4B | 0/0 | 99.5 | 96.1 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 299927 | 300895 | PMRF | 0/0 | 100.0 | 98.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00071 | 5457 | 6326 | ROBA | 0/0 | 100.0 | 99.3 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00011 | 51831 | 52153 | SOXS | 0/0 | 99.7 | 97.8 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00082 | 2642 | 3609 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00088 | 4834 | 5649 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00088 | 881 | 2155 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00001 | 33341 | 34507 | UGD | 0/0 | 100.0 | 96.9 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00001 | 238174 | 239817 | YOGI | 0/0 | 100.0 | 98.3 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1694 | 2554 | aac(3)-IIa_1 | 0/0 | 100 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00096 | 1539 | 2138 | aac(6’)-Ib-cr_1 | 0/0 | 100 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00086 | 1702 | 2490 | aadA5_1 | 0/0 | 100 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00078 | 5421 | 6200 | aph(3’’)-Ib_5 | 0/0 | 97 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00078 | 4585 | 5421 | aph(6)-Id_1 | 0/0 | 100 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00085 | 1224 | 2099 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00096 | 578 | 1408 | blaOXA-1_1 | 0/0 | 100 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00086 | 2621 | 3094 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00006 | 27290 | 28522 | mdf(A)_1 | 0/0 | 100 | 99.9 | Y08743 | mdf(A) | |
| contig00086 | 316 | 1182 | sul1_5 | 0/0 | 100 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00078 | 85 | 900 | sul2_2 | 0/0 | 100 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00080 | 1998 | 3203 | tet(B)_2 | 0/0 | 100 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1694 | 2554 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00096 | 1539 | 2138 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00086 | 1702 | 2490 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00001 | 40681 | 43830 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00005 | 147293 | 150406 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00070 | 5854 | 8958 | acrF | 0/0 | 100.0 | 100.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00034 | 600 | 1262 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00078 | 5421 | 6200 | APH(3’’)-Ib | 0/0 | 97.0 | 99.7 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00078 | 4585 | 5421 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00002 | 70353 | 71172 | bacA | 0/0 | 99.8 | 98.5 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00052 | 10967 | 11689 | baeR | 0/0 | 100.0 | 99.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00052 | 9567 | 10970 | baeS | 0/0 | 100.0 | 98.7 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00012 | 61576 | 62949 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00085 | 1224 | 2099 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00086 | 2621 | 3094 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00010 | 58703 | 59875 | emrA | 0/0 | 100.0 | 97.9 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00010 | 59892 | 61430 | emrB | 0/0 | 100.0 | 98.6 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00003 | 178484 | 179539 | emrK | 0/0 | 100.0 | 98.0 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00010 | 58046 | 58576 | emrR | 0/0 | 100.0 | 99.4 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00003 | 176946 | 178484 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00007 | 81590 | 83233 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00001 | 39465 | 40658 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00007 | 38239 | 39372 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.3 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00005 | 182292 | 183596 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 95.9 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00001 | 128797 | 129954 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00006 | 27290 | 28522 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00003 | 180063 | 180677 | evgA | 0/0 | 100.0 | 99.2 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00003 | 180682 | 184275 | evgS | 0/0 | 100.0 | 96.8 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00038 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00038 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00033 | 5297 | 5710 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00013 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00022 | 30980 | 31363 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00052 | 707 | 1954 | mdtA | 0/0 | 100.0 | 98.1 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00052 | 1954 | 5076 | mdtB | 0/0 | 100.0 | 99.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00052 | 5077 | 8154 | mdtC | 0/0 | 100.0 | 97.7 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00038 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00038 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00032 | 29397 | 30623 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00032 | 19561 | 20769 | mdtH | 0/0 | 100.0 | 99.9 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00019 | 70066 | 71298 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00007 | 112971 | 114002 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00007 | 114002 | 116053 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00007 | 116050 | 117516 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00005 | 126112 | 126586 | mphB | 0/0 | 99.6 | 96.2 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00004 | 86644 | 88392 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00096 | 578 | 1408 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00003 | 63971 | 64939 | pmrF | 0/0 | 100.0 | 98.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00086 | 316 | 1155 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00078 | 85 | 900 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00080 | 1998 | 3203 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00002 | 46586 | 48073 | tolC | 0/0 | 100.0 | 99.9 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 2095 | 3738 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1694 | 2554 | (AGly)aac3-IIa | 0/0 | 100 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00086 | 1702 | 2490 | (AGly)aadA5 | 0/0 | 100 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00078 | 5421 | 6200 | (AGly)strA | 0/0 | 97 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00078 | 4585 | 5421 | (AGly)strB | 0/0 | 100 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00005 | 182292 | 183596 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 95.9 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00007 | 38239 | 39372 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.3 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00001 | 128797 | 129954 | (Bla)ampH_Ecoli | 0/0 | 100 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00085 | 1224 | 2099 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00096 | 578 | 1408 | (Bla)blaOXA-1 | 0/0 | 100 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00013 | 60155 | 62056 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00086 | 316 | 1155 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00078 | 85 | 900 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00080 | 1998 | 3203 | (Tet)tetB | 0/0 | 100 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00086 | 2621 | 3094 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1694 | 2554 | aac(3)-IIe | 0/0 | 100.0 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00096 | 1539 | 2093 | aac(6’)-Ib-D181Y | 0/0 | 100.0 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00086 | 1702 | 2490 | aadA5 | 0/0 | 100.0 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00078 | 5421 | 6200 | aph(3’’)-Ib | 0/0 | 94.2 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00078 | 4585 | 5421 | aph(6)-Id | 0/0 | 100.0 | 100.0 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00085 | 1224 | 2099 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00007 | 38239 | 39372 | blaEC-15 | 0/0 | 100.0 | 98.5 | NG_049081.1 | class C extended-spectrum beta-lactamase EC-15 | CEPHALOSPORIN |
| contig00096 | 578 | 1408 | blaOXA-1 | 0/0 | 100.0 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00086 | 2621 | 3094 | dfrA17 | 0/0 | 100.0 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00086 | 316 | 1155 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00078 | 85 | 900 | sul2 | 0/0 | 100.0 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00080 | 1998 | 3203 | tet(B) | 0/0 | 100.0 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00094 | 1694 | 2554 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00001 | 39465 | 40658 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00001 | 40681 | 43830 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00005 | 147293 | 150406 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00070 | 5854 | 8958 | ACRF | 0/0 | 100.0 | 100.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00034 | 600 | 1262 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00001 | 128797 | 129954 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00086 | 1702 | 2490 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00078 | 5421 | 6200 | APH3-DPRIME | 0/0 | 94.2 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00078 | 4585 | 5421 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00041 | 25297 | 27149 | ASMA | 0/0 | 100.0 | 97.2 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00002 | 70353 | 71172 | BACA | 0/0 | 99.8 | 98.8 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00052 | 10967 | 11689 | BAER | 0/0 | 100.0 | 99.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00052 | 9567 | 10970 | BAES | 0/0 | 100.0 | 98.7 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00017 | 67338 | 68528 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00007 | 38239 | 39372 | BLAEC | 0/0 | 100.0 | 98.5 | MEG_1282 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00012 | 60881 | 61579 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00012 | 61576 | 62949 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00104 | 62 | 1004 | CTX | 0/0 | 100.0 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00086 | 2621 | 3094 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00010 | 58703 | 59875 | EMRA | 0/0 | 100.0 | 97.9 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00010 | 59892 | 61430 | EMRB | 0/0 | 100.0 | 98.6 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00036 | 43241 | 44431 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00003 | 178484 | 179647 | EMRK | 0/0 | 100.0 | 98.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00010 | 58046 | 58576 | EMRR | 0/0 | 100.0 | 99.4 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00003 | 176946 | 178484 | EMRY | 0/0 | 100.0 | 97.7 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00007 | 81590 | 83233 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00003 | 180682 | 184275 | EVGS | 0/0 | 100.0 | 97.2 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00038 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00038 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00033 | 5297 | 5710 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00013 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00022 | 30974 | 31363 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00022 | 30526 | 30960 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00006 | 27290 | 28522 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00052 | 707 | 1954 | MDTA | 0/0 | 100.0 | 98.1 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00052 | 1954 | 5076 | MDTB | 0/0 | 100.0 | 99.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00052 | 5077 | 8154 | MDTC | 0/0 | 100.0 | 97.7 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00038 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00038 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00032 | 29397 | 30623 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00032 | 19561 | 20769 | MDTH | 0/0 | 100.0 | 99.9 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00022 | 63756 | 64085 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00022 | 64072 | 64437 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00021 | 26477 | 27850 | MDTK | 0/0 | 100.0 | 100.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00019 | 70066 | 71298 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00007 | 112971 | 114002 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00007 | 114002 | 116053 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00007 | 116050 | 117516 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00005 | 126112 | 126586 | MPHB | 0/0 | 99.6 | 96.2 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00004 | 86644 | 88392 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00096 | 578 | 1408 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00013 | 60155 | 62056 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00005 | 182292 | 183596 | PBP4B | 0/0 | 100.0 | 95.9 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00003 | 63971 | 64939 | PMRF | 0/0 | 100.0 | 98.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00019 | 21724 | 22593 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00007 | 139132 | 139455 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00086 | 189 | 1156 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00078 | 85 | 900 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00080 | 1998 | 3203 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00080 | 3997 | 4413 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00003 | 2095 | 3738 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00076 | 6262 | 7122 | aac(3)-IId_1 | 0/0 | 100.0 | 99.9 | EU022314 | aac(3)-IId | Gentamicin, Tobramycin |
| contig00003 | 23454 | 24329 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00750 | 109 | 969 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig03356 | 161 | 634 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00666 | 1490 | 2063 | dfrA7_5 | 3/4 | 100.0 | 98.8 | AJ419170 | dfrA7 | Trimethoprim |
| contig01612 | 42 | 551 | dfrA8_1 | 0/0 | 100.0 | 100.0 | U10186 | dfrA8 | Trimethoprim |
| contig00512 | 263 | 1026 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00666 | 180 | 1046 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00905 | 410 | 1656 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| contig00794 | 415 | 1620 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00076 | 6262 | 7122 | AAC(3)-IId | 0/0 | 100.0 | 99.9 | EU022314.1:0-861 | AAC(3)-IId is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00816 | 1149 | 1811 | acrS | 0/0 | 100.0 | 97.9 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00173 | 2765 | 4168 | baeS | 0/0 | 100.0 | 90.1 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig03015 | 101 | 719 | CRP | 0/0 | 97.8 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00003 | 23454 | 24329 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig03356 | 161 | 634 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00666 | 1590 | 2063 | dfrA7 | 0/0 | 100.0 | 100.0 | FJ854362:2338-2812 | dfrA7 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig01612 | 42 | 551 | dfrA8 | 0/0 | 100.0 | 100.0 | KJ174469:710-1220 | dfrA8 is a transposon-encoded dihydrofolate reductase found in Salmonella enterica | diaminopyrimidine |
| contig01821 | 312 | 842 | emrR | 0/0 | 100.0 | 99.2 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00512 | 289 | 1034 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00830 | 225 | 1418 | Escherichia_coli_acrA | 0/0 | 100.0 | 98.9 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig01727 | 66 | 1123 | Escherichia_coli_ampC | 0/0 | 93.3 | 98.2 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00385 | 1398 | 2702 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 95.4 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00665 | 614 | 946 | Escherichia_coli_emrE | 0/0 | 100.0 | 91.9 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00128 | 185 | 3778 | evgS | 0/0 | 100.0 | 96.3 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig01705 | 608 | 1021 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00087 | 5744 | 6421 | kdpE | 0/0 | 100.0 | 96.6 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00670 | 39 | 1271 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00012 | 4008 | 4484 | mphB | 0/0 | 100.0 | 98.1 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00666 | 180 | 1019 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00750 | 109 | 969 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00905 | 410 | 1656 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00794 | 415 | 1620 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00076 | 6262 | 7122 | (AGly)aac3-IId | 0/0 | 100.0 | 99.9 | EU022314:1-861 | (AGly)aac3-IId | NA |
| contig00385 | 1398 | 2702 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 95.4 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig01727 | 66 | 1123 | (Bla)AmpC2_Ecoli | 0/0 | 93.3 | 98.2 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00003 | 23454 | 24329 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00750 | 109 | 969 | (Bla)blaTEM-105 | 0/0 | 100.0 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00512 | 289 | 1026 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00666 | 180 | 1019 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00905 | 410 | 1684 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00794 | 415 | 1620 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig03356 | 161 | 634 | (Tmt)dfrA17 | 0/0 | 100.0 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| contig01612 | 42 | 551 | (Tmt)dfrA8 | 0/0 | 100.0 | 100.0 | U10186:711-1220 | (Tmt)dfrA8 | NA |
| contig00666 | 1590 | 2063 | (Tmt)dhfr7 | 0/0 | 100.0 | 100.0 | X58425:594-1067 | (Tmt)dhfr7 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00076 | 6262 | 7122 | aac(3)-IId | 0/0 | 100.0 | 100.0 | NG_047251.1 | aminoglycoside N-acetyltransferase AAC(3)-IId | GENTAMICIN |
| contig00003 | 23454 | 24329 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig01727 | 66 | 1123 | blaEC-19 | 0/0 | 93.3 | 99.6 | NG_049084.1 | class C extended-spectrum beta-lactamase EC-19 | CEPHALOSPORIN |
| contig00750 | 109 | 969 | blaTEM-1 | 0/0 | 100.0 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig03356 | 161 | 634 | dfrA17 | 0/0 | 100.0 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00666 | 1590 | 2063 | dfrA7 | 0/0 | 100.0 | 100.0 | NG_047737.1 | trimethoprim-resistant dihydrofolate reductase DfrA7 | TRIMETHOPRIM |
| contig01612 | 42 | 551 | dfrA8 | 0/0 | 100.0 | 100.0 | NG_047741.1 | trimethoprim-resistant dihydrofolate reductase DfrA8 | TRIMETHOPRIM |
| contig00512 | 289 | 1026 | erm(B) | 0/0 | 100.0 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00666 | 180 | 1019 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00905 | 485 | 1684 | tet(A) | 0/0 | 100.0 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| contig00794 | 415 | 1620 | tet(B) | 0/0 | 100.0 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00076 | 6262 | 7122 | AAC3 | 0/0 | 100.0 | 100.0 | MEG_64 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00830 | 225 | 1418 | ACRA | 0/0 | 100.0 | 98.9 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00816 | 1149 | 1811 | ACRS | 0/0 | 100.0 | 97.9 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00173 | 2765 | 4168 | BAES | 0/0 | 100.0 | 90.1 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig01259 | 1 | 1124 | BCR | 0/0 | 94.4 | 96.6 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig01727 | 66 | 1123 | BLAEC | 0/0 | 93.3 | 99.6 | MEG_1275 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig03015 | 101 | 719 | CRP | 0/0 | 97.8 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00666 | 1590 | 2063 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2548 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig01612 | 42 | 551 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2553 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig03356 | 161 | 634 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig01821 | 312 | 842 | EMRR | 0/0 | 100.0 | 99.2 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00512 | 263 | 1026 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00128 | 185 | 3778 | EVGS | 0/0 | 100.0 | 97.3 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig01705 | 608 | 1021 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00087 | 5744 | 6421 | KDPE | 0/0 | 100.0 | 96.6 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00670 | 39 | 1271 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00012 | 4008 | 4484 | MPHB | 0/0 | 100.0 | 98.1 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00665 | 614 | 946 | MVRC | 0/0 | 100.0 | 91.9 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00385 | 1398 | 2702 | PBP4B | 0/0 | 100.0 | 95.4 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00666 | 53 | 1020 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00750 | 91 | 1336 | TEM | 0/0 | 98.3 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00905 | 410 | 1684 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00794 | 415 | 1620 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00152 | 71 | 931 | blaSHV-12_1 | 0/0 | 100 | 100.0 | KF976405 | blaSHV-12 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00027 | 64704 | 65564 | blaTEM-1B_1 | 0/0 | 100 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00087 | 1809 | 2282 | dfrA5_1 | 0/0 | 100 | 100.0 | X12868 | dfrA5 | Trimethoprim |
| contig00127 | 264 | 1027 | erm(B)_18 | 2/2 | 100 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00007 | 32486 | 33718 | mdf(A)_1 | 0/0 | 100 | 98.0 | Y08743 | mdf(A) | |
| contig00150 | 69 | 999 | mph(A)_2 | 2/10 | 100 | 98.6 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00087 | 445 | 1311 | sul1_5 | 0/0 | 100 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00006 | 166026 | 169175 | acrB | 0/0 | 100.0 | 99.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00025 | 11499 | 14612 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00029 | 45356 | 46513 | acrE | 0/0 | 100.0 | 97.5 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00029 | 46525 | 49629 | acrF | 0/0 | 100.0 | 97.8 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00029 | 44295 | 44957 | acrS | 0/0 | 100.0 | 98.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 140891 | 141710 | bacA | 0/0 | 99.8 | 97.4 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00004 | 20578 | 21300 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00004 | 19178 | 20581 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00011 | 63633 | 65006 | cpxA | 0/0 | 100.0 | 98.3 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00002 | 280114 | 280746 | CRP | 0/0 | 100.0 | 98.9 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00087 | 1809 | 2282 | dfrA5 | 0/0 | 100.0 | 100.0 | DQ278190:0-474 | dfrA5 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00050 | 23051 | 24223 | emrA | 0/0 | 100.0 | 97.4 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00050 | 24240 | 25778 | emrB | 0/0 | 100.0 | 98.2 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00033 | 19802 | 20857 | emrK | 0/0 | 100.0 | 98.4 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00050 | 22394 | 22924 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00033 | 18264 | 19802 | emrY | 0/0 | 100.0 | 97.5 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00010 | 117851 | 119494 | eptA | 0/0 | 100.0 | 99.2 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00127 | 290 | 1035 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00006 | 169198 | 170391 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.1 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 160219 | 161352 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.1 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00006 | 76537 | 77694 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.6 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00007 | 32486 | 33718 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.5 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00033 | 21381 | 21995 | evgA | 0/0 | 100.0 | 99.5 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00033 | 22000 | 25593 | evgS | 0/0 | 100.0 | 96.7 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00002 | 100122 | 100850 | gadW | 0/0 | 100.0 | 95.5 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00002 | 98929 | 99753 | gadX | 0/0 | 100.0 | 94.3 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00054 | 21273 | 21686 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00009 | 7766 | 8441 | kdpE | 0/0 | 99.7 | 95.7 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00035 | 42525 | 42908 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00004 | 10318 | 11565 | mdtA | 0/0 | 100.0 | 100.0 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00004 | 11565 | 14687 | mdtB | 0/0 | 100.0 | 99.8 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00004 | 14688 | 17765 | mdtC | 0/0 | 100.0 | 99.8 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00002 | 104351 | 105508 | mdtE | 0/0 | 100.0 | 98.5 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00002 | 101213 | 104326 | mdtF | 0/0 | 100.0 | 98.5 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00039 | 21227 | 22453 | mdtG | 0/0 | 100.0 | 97.8 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00039 | 31084 | 32292 | mdtH | 0/0 | 100.0 | 98.3 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00066 | 259 | 1491 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00010 | 94231 | 95262 | mdtN | 0/0 | 100.0 | 96.9 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00010 | 92180 | 94231 | mdtO | 0/0 | 100.0 | 96.4 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00010 | 90717 | 92183 | mdtP | 0/0 | 100.0 | 97.6 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00150 | 69 | 971 | mphA | 0/0 | 99.7 | 99.9 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00023 | 9166 | 9640 | mphB | 0/0 | 99.6 | 96.6 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00020 | 50226 | 51974 | msbA | 0/0 | 100.0 | 98.7 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00017 | 5950 | 6918 | pmrF | 0/0 | 100.0 | 98.7 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00152 | 71 | 931 | SHV-134 | 0/0 | 100.0 | 99.9 | HM559945:0-861 | SHV-134 is an extended-spectrum beta-lactamase. | carbapenem, cephalosporin, penam |
| contig00087 | 445 | 1284 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00027 | 64704 | 65564 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00001 | 117379 | 118866 | tolC | 0/0 | 100.0 | 98.3 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00045 | 30809 | 31975 | ugd | 0/0 | 100.0 | 99.9 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00004 | 159132 | 160775 | yojI | 0/0 | 100.0 | 96.6 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00008 | 160219 | 161352 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 98.1 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00006 | 76537 | 77694 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 98.6 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00152 | 71 | 931 | (Bla)blaSHV-12 | 0/0 | 100.0 | 100.0 | FJ685654:24-860 | (Bla)blaSHV-12 | NA |
| contig00027 | 64704 | 65564 | (Bla)blaTEM-105 | 0/0 | 100.0 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00009 | 46838 | 48739 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 99.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00127 | 290 | 1027 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00150 | 69 | 971 | (MLS)mph(A) | 0/0 | 99.7 | 99.9 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00087 | 445 | 1284 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00087 | 1809 | 2282 | (Tmt)dfrA5 | 0/0 | 100.0 | 100.0 | X12868:1306-1779 | (Tmt)dfrA5 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00008 | 160219 | 161352 | blaEC-8 | 0/0 | 100 | 99.8 | NG_049086.1 | cephalosporin-hydrolyzing class C beta-lactamase EC-8 | CEPHALOSPORIN |
| contig00152 | 71 | 931 | blaSHV-12 | 0/0 | 100 | 100.0 | NG_050590.1 | class A extended-spectrum beta-lactamase SHV-12 | CEPHALOSPORIN |
| contig00027 | 64704 | 65564 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00087 | 1809 | 2282 | dfrA5 | 0/0 | 100 | 100.0 | NG_051699.1 | trimethoprim-resistant dihydrofolate reductase DfrA5 | TRIMETHOPRIM |
| contig00127 | 290 | 1027 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00150 | 69 | 999 | mph(A) | 2/10 | 100 | 98.6 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00087 | 445 | 1284 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00006 | 169198 | 170391 | ACRA | 0/0 | 100.0 | 99.1 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00006 | 166026 | 169175 | ACRB | 0/0 | 100.0 | 99.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00025 | 11499 | 14612 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00029 | 45356 | 46513 | ACRE | 0/0 | 100.0 | 97.5 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00029 | 46525 | 49629 | ACRF | 0/0 | 100.0 | 97.8 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00029 | 44295 | 44957 | ACRS | 0/0 | 100.0 | 98.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00006 | 76537 | 77694 | AMPH | 0/0 | 100.0 | 98.6 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00076 | 10489 | 12342 | ASMA | 0/0 | 100.0 | 97.7 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00001 | 140891 | 141710 | BACA | 0/0 | 99.8 | 97.9 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00004 | 20578 | 21300 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00004 | 19178 | 20581 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00004 | 132672 | 133862 | BCR | 0/0 | 100.0 | 95.2 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00008 | 160219 | 161352 | BLAEC | 0/0 | 100.0 | 99.8 | MEG_1278 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00011 | 62938 | 63636 | CPXAR | 0/0 | 100.0 | 99.6 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00011 | 63633 | 65006 | CPXAR | 0/0 | 100.0 | 98.5 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00002 | 280114 | 280746 | CRP | 0/0 | 100.0 | 98.9 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00087 | 1809 | 2282 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2546 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00050 | 23051 | 24223 | EMRA | 0/0 | 100.0 | 97.4 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00050 | 24240 | 25778 | EMRB | 0/0 | 100.0 | 98.2 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00056 | 1479 | 2669 | EMRD | 0/0 | 100.0 | 97.2 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00033 | 19802 | 20965 | EMRK | 0/0 | 100.0 | 98.5 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00050 | 22394 | 22924 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00033 | 18264 | 19802 | EMRY | 0/0 | 100.0 | 97.5 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00010 | 117851 | 119494 | EPTA | 0/0 | 100.0 | 99.2 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00127 | 264 | 1027 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00033 | 22000 | 25593 | EVGS | 0/0 | 100.0 | 97.3 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00002 | 100122 | 100850 | GADW | 0/0 | 100.0 | 97.7 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00002 | 98929 | 99753 | GADX | 0/0 | 100.0 | 94.3 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00054 | 21273 | 21686 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00009 | 7766 | 8441 | KDPE | 0/0 | 99.7 | 95.7 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00035 | 42519 | 42908 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00035 | 42070 | 42504 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00007 | 32486 | 33718 | MDFA | 0/0 | 100.0 | 98.1 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00004 | 10318 | 11565 | MDTA | 0/0 | 100.0 | 100.0 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00004 | 11565 | 14687 | MDTB | 0/0 | 100.0 | 99.8 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00004 | 14688 | 17765 | MDTC | 0/0 | 100.0 | 99.8 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00002 | 104351 | 105508 | MDTE | 0/0 | 100.0 | 98.5 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00002 | 101213 | 104326 | MDTF | 0/0 | 100.0 | 98.5 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00039 | 21227 | 22453 | MDTG | 0/0 | 100.0 | 98.2 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00039 | 31084 | 32292 | MDTH | 0/0 | 100.0 | 98.3 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00041 | 30311 | 30640 | MDTI | 0/0 | 100.0 | 99.4 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00041 | 30627 | 30992 | MDTJ | 0/0 | 100.0 | 98.6 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00003 | 194899 | 196271 | MDTK | 0/0 | 99.9 | 98.4 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00066 | 259 | 1491 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00010 | 94231 | 95262 | MDTN | 0/0 | 100.0 | 96.9 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00010 | 92180 | 94231 | MDTO | 0/0 | 100.0 | 96.4 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00010 | 90717 | 92183 | MDTP | 0/0 | 100.0 | 97.6 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00150 | 69 | 999 | MPHA | 2/10 | 100.0 | 98.6 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00023 | 9166 | 9640 | MPHB | 0/0 | 99.6 | 96.6 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00020 | 50226 | 51974 | MSBA | 0/0 | 100.0 | 98.7 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00009 | 46838 | 48739 | PBP2 | 0/0 | 100.0 | 99.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00017 | 5950 | 6918 | PMRF | 0/0 | 100.0 | 98.7 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00005 | 151816 | 152685 | ROBA | 0/0 | 100.0 | 97.1 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00152 | 25 | 1028 | SHV | 0/0 | 99.7 | 98.9 | MEG_6428 | Drugs:betalactams:Class_A_betalactamases:SHV | NA |
| contig00010 | 68752 | 69074 | SOXS | 0/0 | 99.7 | 98.1 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00087 | 318 | 1285 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00027 | 64337 | 65582 | TEM | 0/0 | 98.3 | 99.3 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00045 | 30809 | 31975 | UGD | 0/0 | 100.0 | 99.9 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00004 | 159132 | 160775 | YOGI | 0/0 | 100.0 | 96.6 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00031 | 21738 | 22613 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00061 | 1218 | 2450 | mdf(A)_1 | 0/0 | 100 | 99.1 | Y08743 | mdf(A) | |
| contig00031 | 27254 | 27910 | qnrS1_1 | 0/0 | 100 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00005 | 124681 | 127830 | acrB | 0/0 | 100.0 | 99.1 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00035 | 17245 | 20358 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00029 | 8449 | 9606 | acrE | 0/0 | 100.0 | 99.0 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00029 | 5333 | 8437 | acrF | 0/0 | 100.0 | 99.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00029 | 10005 | 10667 | acrS | 0/0 | 100.0 | 98.6 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00067 | 8182 | 9001 | bacA | 0/0 | 99.8 | 98.7 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00008 | 11081 | 11803 | baeR | 0/0 | 100.0 | 99.5 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00008 | 11800 | 13203 | baeS | 0/0 | 100.0 | 98.7 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00036 | 22414 | 23787 | cpxA | 0/0 | 100.0 | 98.5 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00052 | 15000 | 15632 | CRP | 0/0 | 100.0 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00031 | 21738 | 22613 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00063 | 20022 | 21194 | emrA | 0/0 | 100.0 | 98.2 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00063 | 21211 | 22749 | emrB | 0/0 | 100.0 | 98.5 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00020 | 4530 | 5585 | emrK | 0/0 | 100.0 | 98.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00063 | 19365 | 19895 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00020 | 2992 | 4530 | emrY | 0/0 | 100.0 | 98.8 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00048 | 17465 | 19108 | eptA | 0/0 | 100.0 | 99.2 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00005 | 127853 | 129046 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.8 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00078 | 8727 | 9860 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.2 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00020 | 63862 | 65166 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00005 | 36337 | 37494 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.7 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00046 | 2507 | 2839 | Escherichia_coli_emrE | 0/0 | 100.0 | 92.2 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00061 | 1218 | 2450 | Escherichia_coli_mdfA | 0/0 | 100.0 | 97.6 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00020 | 6109 | 6723 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00020 | 6728 | 10321 | evgS | 0/0 | 100.0 | 99.5 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00011 | 103823 | 104551 | gadW | 0/0 | 100.0 | 94.4 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00011 | 104919 | 105743 | gadX | 0/0 | 100.0 | 97.8 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00009 | 55089 | 55502 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00024 | 8068 | 8740 | kdpE | 0/0 | 99.3 | 97.2 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00018 | 9298 | 9681 | marA | 0/0 | 100.0 | 99.5 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 20816 | 22063 | mdtA | 0/0 | 100.0 | 98.2 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00008 | 17694 | 20816 | mdtB | 0/0 | 100.0 | 98.0 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00008 | 14616 | 17693 | mdtC | 0/0 | 100.0 | 98.1 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00011 | 99165 | 100322 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00011 | 100347 | 103460 | mdtF | 0/0 | 100.0 | 98.6 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00013 | 100113 | 101339 | mdtG | 0/0 | 100.0 | 99.2 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00013 | 90274 | 91482 | mdtH | 0/0 | 100.0 | 98.8 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00015 | 4255 | 5286 | mdtN | 0/0 | 100.0 | 98.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00015 | 5286 | 7337 | mdtO | 0/0 | 100.0 | 98.8 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00015 | 7334 | 8800 | mdtP | 0/0 | 100.0 | 98.2 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00037 | 4214 | 4690 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00004 | 51527 | 53275 | msbA | 0/0 | 100.0 | 99.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00001 | 124221 | 125189 | pmrF | 0/0 | 100.0 | 99.4 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00031 | 27254 | 27910 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00032 | 36175 | 37662 | tolC | 0/0 | 100.0 | 98.4 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 77989 | 79155 | ugd | 0/0 | 100.0 | 95.9 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00001 | 75559 | 77202 | yojI | 0/0 | 100.0 | 98.2 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00020 | 63862 | 65166 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 98.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00078 | 8727 | 9860 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.2 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00005 | 36337 | 37494 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.7 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00031 | 21738 | 22613 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00024 | 60529 | 62430 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 98.7 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00031 | 27254 | 27910 | (Flq)qnr-S1 | 0/0 | 100 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00031 | 21738 | 22613 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00078 | 8727 | 9860 | blaEC-13 | 0/0 | 100 | 99.6 | NG_049079.1 | class C extended-spectrum beta-lactamase EC-13 | CEPHALOSPORIN |
| contig00031 | 27254 | 27910 | qnrS1 | 0/0 | 100 | 100.0 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00005 | 127853 | 129046 | ACRA | 0/0 | 100.0 | 99.8 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00005 | 124681 | 127830 | ACRB | 0/0 | 100.0 | 99.1 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00035 | 17245 | 20358 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00029 | 8449 | 9606 | ACRE | 0/0 | 100.0 | 99.0 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00029 | 5333 | 8437 | ACRF | 0/0 | 100.0 | 99.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00029 | 10005 | 10667 | ACRS | 0/0 | 100.0 | 98.6 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00005 | 36337 | 37494 | AMPH | 0/0 | 100.0 | 98.7 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00008 | 33670 | 35522 | ASMA | 0/0 | 100.0 | 98.1 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00067 | 8182 | 9001 | BACA | 0/0 | 99.8 | 98.9 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00008 | 11081 | 11803 | BAER | 0/0 | 100.0 | 99.5 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00008 | 11800 | 13203 | BAES | 0/0 | 100.0 | 98.7 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 49097 | 50287 | BCR | 0/0 | 100.0 | 98.2 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00078 | 8727 | 9860 | BLAEC | 0/0 | 100.0 | 99.6 | MEG_1280 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00036 | 21719 | 22417 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00036 | 22414 | 23787 | CPXAR | 0/0 | 100.0 | 99.1 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00052 | 15000 | 15632 | CRP | 0/0 | 100.0 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00063 | 20022 | 21194 | EMRA | 0/0 | 100.0 | 98.2 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00063 | 21211 | 22749 | EMRB | 0/0 | 100.0 | 98.5 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00007 | 27098 | 28288 | EMRD | 0/0 | 100.0 | 99.9 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00020 | 4530 | 5693 | EMRK | 0/0 | 100.0 | 98.8 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00063 | 19365 | 19895 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00020 | 2992 | 4530 | EMRY | 0/0 | 100.0 | 98.9 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00048 | 17465 | 19108 | EPTA | 0/0 | 100.0 | 99.2 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00020 | 6728 | 10321 | EVGS | 0/0 | 100.0 | 99.5 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00011 | 103823 | 104551 | GADW | 0/0 | 100.0 | 98.6 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00011 | 104919 | 105743 | GADX | 0/0 | 100.0 | 97.8 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00009 | 55089 | 55502 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00024 | 8068 | 8740 | KDPE | 0/0 | 99.3 | 97.2 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00018 | 9292 | 9681 | MARA | 0/0 | 100.0 | 99.5 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00018 | 8844 | 9278 | MARR | 0/0 | 100.0 | 97.7 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00061 | 1218 | 2450 | MDFA | 0/0 | 100.0 | 99.2 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00008 | 20816 | 22063 | MDTA | 0/0 | 100.0 | 98.2 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00008 | 17694 | 20816 | MDTB | 0/0 | 100.0 | 98.0 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00008 | 14616 | 17693 | MDTC | 0/0 | 100.0 | 98.1 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00011 | 99165 | 100322 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00011 | 100347 | 103460 | MDTF | 0/0 | 100.0 | 98.6 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00013 | 100113 | 101339 | MDTG | 0/0 | 100.0 | 99.3 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00013 | 90274 | 91482 | MDTH | 0/0 | 100.0 | 98.8 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00018 | 48327 | 48656 | MDTI | 0/0 | 100.0 | 99.7 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00018 | 48643 | 49008 | MDTJ | 0/0 | 100.0 | 98.9 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00010 | 71668 | 73041 | MDTK | 0/0 | 100.0 | 99.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00015 | 4255 | 5286 | MDTN | 0/0 | 100.0 | 98.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00015 | 5286 | 7337 | MDTO | 0/0 | 100.0 | 98.8 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00015 | 7334 | 8800 | MDTP | 0/0 | 100.0 | 98.2 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00037 | 4214 | 4690 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00004 | 51527 | 53275 | MSBA | 0/0 | 100.0 | 99.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00046 | 2507 | 2839 | MVRC | 0/0 | 100.0 | 92.2 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00024 | 60529 | 62430 | PBP2 | 0/0 | 100.0 | 98.7 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00020 | 63862 | 65166 | PBP4B | 0/0 | 100.0 | 98.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 124221 | 125189 | PMRF | 0/0 | 100.0 | 99.4 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00031 | 27254 | 27910 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00014 | 11922 | 12791 | ROBA | 0/0 | 100.0 | 99.1 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00015 | 30417 | 30739 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00008 | 77989 | 79155 | UGD | 0/0 | 100.0 | 95.9 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00001 | 75559 | 77202 | YOGI | 0/0 | 100.0 | 98.2 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00034 | 4557 | 5360 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00034 | 3721 | 4557 | aph(6)-Id_1 | 0/0 | 100.0 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00228 | 3498 | 4373 | blaCTX-M-121_1 | 0/0 | 100.0 | 100.0 | JN790862 | blaCTX-M-121 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig01175 | 46 | 921 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00034 | 2140 | 3000 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00821 | 181 | 663 | dfrA14_5 | 0/0 | 100.0 | 99.6 | DQ388123 | dfrA14 | Trimethoprim |
| contig00173 | 3600 | 4256 | qnrS1_1 | 0/0 | 100.0 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| contig00034 | 5421 | 6236 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00378 | 1676 | 2922 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00119 | 2469 | 5618 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00168 | 733 | 3846 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00034 | 4557 | 5360 | APH(3’’)-Ib | 0/0 | 100.0 | 99.8 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00034 | 3721 | 4557 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00439 | 922 | 1743 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00595 | 1173 | 1895 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00555 | 429 | 1802 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00228 | 3498 | 4373 | CTX-M-121 | 0/0 | 100.0 | 100.0 | JN790862:244-1120 | CTX-M-121 is a beta-lactamase found in Escherichia coli | cephalosporin |
| contig01175 | 46 | 921 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00821 | 181 | 663 | dfrA14 | 0/0 | 100.0 | 99.8 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00658 | 1051 | 2150 | emrA | 0/0 | 93.8 | 99.9 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00327 | 2290 | 3345 | emrK | 0/0 | 100.0 | 99.9 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00658 | 394 | 924 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00327 | 752 | 2290 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00119 | 1253 | 2446 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00347 | 1062 | 2219 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00117 | 3826 | 4158 | Escherichia_coli_emrE | 0/0 | 100.0 | 91.9 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig01773 | 225 | 839 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00500 | 1981 | 2691 | gadW | 0/0 | 97.5 | 94.5 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00500 | 789 | 1613 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig01162 | 154 | 567 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00312 | 1550 | 2707 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00015 | 3182 | 4408 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00056 | 6447 | 7478 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00056 | 4396 | 6447 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00056 | 2933 | 4399 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00576 | 1090 | 1564 | mphB | 0/0 | 99.6 | 97.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig01927 | 170 | 646 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00022 | 7330 | 9078 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00193 | 2029 | 2997 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00173 | 3600 | 4256 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00034 | 5421 | 6236 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00034 | 2140 | 3000 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00378 | 1676 | 2922 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00003 | 8582 | 9748 | ugd | 0/0 | 100.0 | 95.6 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00007 | 4872 | 6038 | ugd | 0/0 | 100.0 | 96.1 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00034 | 4557 | 5360 | (AGly)strA | 0/0 | 100 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00034 | 3721 | 4557 | (AGly)strB | 0/0 | 100 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00347 | 1062 | 2219 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00228 | 3498 | 4373 | (Bla)blaCTX-M-121 | 0/0 | 100 | 100.0 | JN790862:245-1120 | (Bla)blaCTX-M-121 | NA |
| contig01175 | 46 | 921 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00034 | 2140 | 3000 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00173 | 3600 | 4256 | (Flq)qnr-S1 | 0/0 | 100 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| contig00034 | 5421 | 6236 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00378 | 1648 | 2922 | (Tet)tetA | 0/0 | 100 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00821 | 181 | 654 | (Tmt)dfrA14 | 0/0 | 100 | 100.0 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00034 | 4557 | 5384 | aph(3’’)-Ib | 0/0 | 100 | 100 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00034 | 3721 | 4557 | aph(6)-Id | 0/0 | 100 | 100 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00228 | 3498 | 4373 | blaCTX-M-121 | 0/0 | 100 | 100 | NG_048914.1 | class A extended-spectrum beta-lactamase CTX-M-121 | CEPHALOSPORIN |
| contig01175 | 46 | 921 | blaCTX-M-15 | 0/0 | 100 | 100 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00034 | 2140 | 3000 | blaTEM-1 | 0/0 | 100 | 100 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00821 | 181 | 654 | dfrA14 | 0/0 | 100 | 100 | NG_056035.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| contig00173 | 3600 | 4256 | qnrS1 | 0/0 | 100 | 100 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| contig00034 | 5421 | 6236 | sul2 | 0/0 | 100 | 100 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00378 | 1648 | 2847 | tet(A) | 0/0 | 100 | 100 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00119 | 1253 | 2446 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00119 | 2469 | 5618 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00168 | 733 | 3846 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00347 | 1062 | 2219 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00034 | 4557 | 5384 | APH3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00034 | 3721 | 4557 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00439 | 922 | 1743 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00595 | 1173 | 1895 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00174 | 1152 | 2342 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00555 | 429 | 1802 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00228 | 2521 | 3463 | CTX | 0/0 | 100.0 | 98.9 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00228 | 3492 | 4395 | CTX | 0/0 | 100.0 | 99.7 | MEG_2401 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00821 | 181 | 654 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00658 | 1051 | 2150 | EMRA | 0/0 | 93.8 | 99.9 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00327 | 2290 | 3453 | EMRK | 0/0 | 100.0 | 99.9 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00658 | 394 | 924 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00327 | 752 | 2290 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00500 | 1981 | 2691 | GADW | 0/0 | 97.5 | 99.9 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00500 | 789 | 1613 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig01162 | 154 | 567 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig01127 | 916 | 1350 | MARR | 0/0 | 100.0 | 98.4 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig02203 | 193 | 627 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00312 | 1550 | 2707 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00015 | 3182 | 4408 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00390 | 1297 | 1626 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00390 | 945 | 1310 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00056 | 6447 | 7478 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00056 | 4396 | 6447 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00056 | 2933 | 4399 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00576 | 1090 | 1564 | MPHB | 0/0 | 99.6 | 97.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig01927 | 170 | 646 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00022 | 7330 | 9078 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00117 | 3826 | 4158 | MVRC | 0/0 | 100.0 | 91.9 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00193 | 2029 | 2997 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00173 | 3600 | 4256 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00604 | 1660 | 1982 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00034 | 5421 | 6236 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00034 | 1773 | 3018 | TEM | 0/0 | 98.3 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00378 | 1648 | 2922 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00003 | 8582 | 9748 | UGD | 0/0 | 100.0 | 95.6 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00007 | 4872 | 6038 | UGD | 0/0 | 100.0 | 96.1 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00064 | 2526 | 3327 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00066 | 919 | 1722 | aph(3’’)-Ib_5 | 0/0 | 100.0 | 99.9 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00066 | 83 | 919 | aph(6)-Id_1 | 0/0 | 100.0 | 99.8 | M28829 | aph(6)-Id | Streptomycin |
| contig00061 | 427 | 1302 | blaCTX-M-27_1 | 0/0 | 100.0 | 100.0 | AY156923 | blaCTX-M-27 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00086 | 109 | 969 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00056 | 1 | 660 | catA1_1 | 0/0 | 100.0 | 99.8 | V00622 | catA1 | Chloramphenicol |
| contig00064 | 3725 | 4222 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00107 | 4 | 486 | dfrA14_5 | 0/0 | 100.0 | 99.6 | DQ388123 | dfrA14 | Trimethoprim |
| contig00070 | 266 | 1029 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00010 | 78274 | 79506 | mdf(A)_1 | 0/0 | 100.0 | 98.5 | Y08743 | mdf(A) | |
| contig00059 | 4118 | 5048 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00064 | 1182 | 2048 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00066 | 1783 | 2598 | sul2_2 | 0/0 | 100.0 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00071 | 1097 | 2301 | tet(B)_2 | 0/0 | 99.9 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00064 | 2526 | 3305 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00011 | 73090 | 76239 | acrB | 0/0 | 100.0 | 99.1 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 135661 | 138774 | acrD | 0/0 | 100.0 | 99.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00014 | 114452 | 115609 | acrE | 0/0 | 100.0 | 98.8 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00014 | 115621 | 118725 | acrF | 0/0 | 100.0 | 98.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00014 | 113391 | 114053 | acrS | 0/0 | 100.0 | 98.9 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00066 | 919 | 1722 | APH(3’’)-Ib | 0/0 | 100.0 | 99.6 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00066 | 83 | 919 | APH(6)-Id | 0/0 | 100.0 | 99.6 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00002 | 77356 | 78175 | bacA | 0/0 | 99.8 | 98.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00022 | 48811 | 49533 | baeR | 0/0 | 100.0 | 99.5 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00022 | 47411 | 48814 | baeS | 0/0 | 100.0 | 98.7 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00056 | 1 | 660 | catI | 0/0 | 100.0 | 99.8 | V00622:243-903 | catI is a chromosome and transposon-encoded variant of the cat gene found in Escherichia coli and Acinetobacter baumannii | phenicol |
| contig00023 | 67580 | 68953 | cpxA | 0/0 | 100.0 | 98.8 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00004 | 15000 | 15632 | CRP | 0/0 | 100.0 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00061 | 427 | 1302 | CTX-M-27 | 0/0 | 100.0 | 100.0 | AY156923:0-876 | CTX-M-27 is a beta-lactamase found in Escherichia coli | cephalosporin |
| contig00064 | 3725 | 4222 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00107 | 4 | 486 | dfrA14 | 0/0 | 100.0 | 99.8 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00025 | 59204 | 60376 | emrA | 0/0 | 100.0 | 98.2 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00025 | 60393 | 61931 | emrB | 0/0 | 100.0 | 99.2 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00003 | 208568 | 209623 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00025 | 58547 | 59077 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00003 | 207030 | 208568 | emrY | 0/0 | 100.0 | 98.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00009 | 136387 | 138030 | eptA | 0/0 | 100.0 | 99.4 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00070 | 292 | 1037 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00011 | 71874 | 73067 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.8 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00009 | 180237 | 181370 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.5 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00008 | 169892 | 171196 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00011 | 161111 | 162268 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.7 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00010 | 78274 | 79506 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.9 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00003 | 210147 | 210761 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00003 | 210766 | 214359 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00004 | 181934 | 182662 | gadW | 0/0 | 100.0 | 94.8 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00004 | 183030 | 183854 | gadX | 0/0 | 100.0 | 97.9 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00007 | 204568 | 204981 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00013 | 8162 | 8834 | kdpE | 0/0 | 99.3 | 97.3 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00016 | 52571 | 52954 | marA | 0/0 | 100.0 | 99.2 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00022 | 38551 | 39798 | mdtA | 0/0 | 100.0 | 98.0 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00022 | 39798 | 42920 | mdtB | 0/0 | 100.0 | 98.7 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00022 | 42921 | 45998 | mdtC | 0/0 | 100.0 | 98.2 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00004 | 177276 | 178433 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00004 | 178458 | 181571 | mdtF | 0/0 | 100.0 | 98.6 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00005 | 176904 | 178130 | mdtG | 0/0 | 100.0 | 99.2 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00005 | 167065 | 168273 | mdtH | 0/0 | 100.0 | 98.9 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00012 | 117206 | 118438 | mdtM | 0/0 | 100.0 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00009 | 112702 | 113733 | mdtN | 0/0 | 100.0 | 98.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00009 | 110651 | 112702 | mdtO | 0/0 | 100.0 | 98.7 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00009 | 109188 | 110654 | mdtP | 0/0 | 100.0 | 98.2 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00059 | 4146 | 5048 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00008 | 113908 | 114382 | mphB | 0/0 | 99.6 | 97.5 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00018 | 24523 | 26271 | msbA | 0/0 | 100.0 | 99.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00003 | 57890 | 58858 | pmrF | 0/0 | 100.0 | 99.7 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00064 | 1182 | 2021 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00066 | 1783 | 2598 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00086 | 109 | 969 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00071 | 1097 | 2301 | tet(B) | 0/0 | 99.9 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00002 | 100534 | 102021 | tolC | 0/0 | 100.0 | 98.5 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 2012 | 3655 | yojI | 0/0 | 100.0 | 98.2 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00064 | 2526 | 3305 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00066 | 919 | 1722 | (AGly)strA | 0/0 | 100.0 | 99.8 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00066 | 83 | 919 | (AGly)strB | 0/0 | 100.0 | 99.8 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00008 | 169892 | 171196 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 98.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00009 | 180237 | 181370 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 97.5 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00011 | 161111 | 162268 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 98.7 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00061 | 427 | 1302 | (Bla)blaCTX-M-27 | 0/0 | 100.0 | 100.0 | AY156923:1-876 | (Bla)blaCTX-M-27 | NA |
| contig00086 | 109 | 969 | (Bla)blaTEM-105 | 0/0 | 100.0 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00013 | 60623 | 62524 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 99.4 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00070 | 292 | 1029 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00059 | 4146 | 5048 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00056 | 1 | 660 | (Phe)catA1 | 0/0 | 100.0 | 99.8 | V00622:244-903 | (Phe)catA1 | NA |
| contig00064 | 1182 | 2021 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00066 | 1783 | 2598 | (Sul)sul2 | 0/0 | 100.0 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00071 | 1097 | 2301 | (Tet)tetB | 0/0 | 99.9 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00064 | 3725 | 4222 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| contig00107 | 4 | 477 | (Tmt)dfrA14 | 0/0 | 100.0 | 100.0 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00064 | 2526 | 3317 | aadA2 | 0/0 | 100.0 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00066 | 919 | 1746 | aph(3’’)-Ib | 0/0 | 100.0 | 99.9 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00066 | 83 | 919 | aph(6)-Id | 0/0 | 100.0 | 99.9 | NG_047466.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00061 | 427 | 1302 | blaCTX-M-27 | 0/0 | 100.0 | 100.0 | NG_048976.1 | class A extended-spectrum beta-lactamase CTX-M-27 | CEPHALOSPORIN |
| contig00009 | 180237 | 181370 | blaEC-18 | 0/0 | 100.0 | 99.2 | NG_049083.1 | class C extended-spectrum beta-lactamase EC-18 | CEPHALOSPORIN |
| contig00086 | 109 | 969 | blaTEM-1 | 0/0 | 100.0 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00056 | 1 | 660 | catA1 | 0/0 | 100.0 | 99.8 | NG_047582.1 | type A-1 chloramphenicol O-acetyltransferase | CHLORAMPHENICOL |
| contig00064 | 3725 | 4222 | dfrA12 | 0/0 | 100.0 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00107 | 4 | 477 | dfrA14 | 0/0 | 100.0 | 100.0 | NG_056035.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| contig00070 | 292 | 1029 | erm(B) | 0/0 | 100.0 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00059 | 4118 | 5048 | mph(A) | 2/10 | 100.0 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00064 | 1182 | 2021 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00066 | 1783 | 2598 | sul2 | 0/0 | 100.0 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00071 | 1097 | 2301 | tet(B) | 0/0 | 99.9 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00011 | 71874 | 73067 | ACRA | 0/0 | 100.0 | 99.8 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00011 | 73090 | 76239 | ACRB | 0/0 | 100.0 | 99.1 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00008 | 135661 | 138774 | ACRD | 0/0 | 100.0 | 99.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00014 | 114452 | 115609 | ACRE | 0/0 | 100.0 | 98.8 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00014 | 115621 | 118725 | ACRF | 0/0 | 100.0 | 98.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00014 | 113391 | 114053 | ACRS | 0/0 | 100.0 | 98.9 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00011 | 161111 | 162268 | AMPH | 0/0 | 100.0 | 98.7 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00064 | 2526 | 3327 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00066 | 919 | 1746 | APH3-DPRIME | 0/0 | 100.0 | 99.9 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00066 | 83 | 919 | APH6 | 0/0 | 100.0 | 99.9 | MEG_1084 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00022 | 24763 | 26616 | ASMA | 0/0 | 100.0 | 96.1 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00002 | 77356 | 78175 | BACA | 0/0 | 99.8 | 98.9 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00022 | 48811 | 49533 | BAER | 0/0 | 100.0 | 99.5 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00022 | 47411 | 48814 | BAES | 0/0 | 100.0 | 98.7 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00017 | 85269 | 86459 | BCR | 0/0 | 100.0 | 98.2 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00009 | 180237 | 181370 | BLAEC | 0/0 | 100.0 | 99.2 | MEG_1279 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00056 | 1 | 660 | CATA | 0/0 | 100.0 | 100.0 | MEG_1584 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00023 | 66885 | 67583 | CPXAR | 0/0 | 100.0 | 99.7 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00023 | 67580 | 68953 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00004 | 15000 | 15632 | CRP | 0/0 | 100.0 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00061 | 405 | 1308 | CTX | 0/0 | 100.0 | 99.8 | MEG_2401 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00061 | 1337 | 2279 | CTX | 0/0 | 100.0 | 100.0 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00064 | 3725 | 4222 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00107 | 4 | 477 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00025 | 59204 | 60376 | EMRA | 0/0 | 100.0 | 98.2 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00025 | 60393 | 61931 | EMRB | 0/0 | 100.0 | 99.2 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00006 | 131531 | 132721 | EMRD | 0/0 | 100.0 | 99.9 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00003 | 208568 | 209731 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00025 | 58547 | 59077 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00003 | 207030 | 208568 | EMRY | 0/0 | 100.0 | 98.8 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00009 | 136387 | 138030 | EPTA | 0/0 | 100.0 | 99.4 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00070 | 266 | 1029 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00003 | 210766 | 214359 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00004 | 181934 | 182662 | GADW | 0/0 | 100.0 | 99.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00004 | 183030 | 183854 | GADX | 0/0 | 100.0 | 97.9 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00007 | 204568 | 204981 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00013 | 8162 | 8834 | KDPE | 0/0 | 99.3 | 97.3 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00016 | 52565 | 52954 | MARA | 0/0 | 100.0 | 99.2 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00016 | 52117 | 52551 | MARR | 0/0 | 100.0 | 97.9 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00010 | 78274 | 79506 | MDFA | 0/0 | 100.0 | 98.5 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00022 | 38551 | 39798 | MDTA | 0/0 | 100.0 | 98.0 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00022 | 39798 | 42920 | MDTB | 0/0 | 100.0 | 98.7 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00022 | 42921 | 45998 | MDTC | 0/0 | 100.0 | 98.2 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00004 | 177276 | 178433 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00004 | 178458 | 181571 | MDTF | 0/0 | 100.0 | 98.6 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00005 | 176904 | 178130 | MDTG | 0/0 | 100.0 | 99.3 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00005 | 167065 | 168273 | MDTH | 0/0 | 100.0 | 98.9 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00016 | 91600 | 91929 | MDTI | 0/0 | 100.0 | 99.7 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00016 | 91916 | 92281 | MDTJ | 0/0 | 100.0 | 98.1 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00001 | 335484 | 336857 | MDTK | 0/0 | 100.0 | 99.1 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00012 | 117206 | 118438 | MDTM | 0/0 | 100.0 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00009 | 112702 | 113733 | MDTN | 0/0 | 100.0 | 98.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00009 | 110651 | 112702 | MDTO | 0/0 | 100.0 | 98.7 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00009 | 109188 | 110654 | MDTP | 0/0 | 100.0 | 98.2 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00059 | 4118 | 5048 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00008 | 113908 | 114382 | MPHB | 0/0 | 99.6 | 97.5 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00018 | 24523 | 26271 | MSBA | 0/0 | 100.0 | 99.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00013 | 60623 | 62524 | PBP2 | 0/0 | 100.0 | 99.4 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00008 | 169892 | 171196 | PBP4B | 0/0 | 100.0 | 98.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00003 | 57890 | 58858 | PMRF | 0/0 | 100.0 | 99.7 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00012 | 47447 | 48316 | ROBA | 0/0 | 100.0 | 99.4 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00009 | 87250 | 87572 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00064 | 1055 | 2022 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00066 | 1783 | 2598 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00071 | 1097 | 2301 | TETB | 0/0 | 99.9 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00003 | 2012 | 3655 | YOGI | 0/0 | 100.0 | 98.2 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00118 | 1695 | 2555 | aac(3)-IIa_1 | 0/0 | 100 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00122 | 1539 | 2138 | aac(6’)-Ib-cr_1 | 0/0 | 100 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00107 | 1702 | 2490 | aadA5_1 | 0/0 | 100 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00110 | 221 | 1096 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00122 | 578 | 1408 | blaOXA-1_1 | 0/0 | 100 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00107 | 2621 | 3094 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00029 | 30138 | 31370 | mdf(A)_1 | 0/0 | 100 | 99.9 | Y08743 | mdf(A) | |
| contig00111 | 2639 | 3560 | mph(A)_2 | 1/1 | 100 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00107 | 316 | 1182 | sul1_5 | 0/0 | 100 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00104 | 1718 | 2923 | tet(B)_2 | 0/0 | 100 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00118 | 1695 | 2555 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00122 | 1539 | 2138 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00107 | 1702 | 2490 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00008 | 39134 | 42283 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 375904 | 379017 | acrD | 0/0 | 100.0 | 98.9 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00007 | 121749 | 122906 | acrE | 0/0 | 100.0 | 99.0 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00007 | 122918 | 126022 | acrF | 0/0 | 100.0 | 100.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00007 | 120688 | 121350 | acrS | 0/0 | 100.0 | 99.4 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00010 | 52778 | 53597 | bacA | 0/0 | 99.8 | 98.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00035 | 29069 | 29791 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00035 | 27669 | 29072 | baeS | 0/0 | 100.0 | 99.9 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00046 | 23043 | 24416 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00018 | 15081 | 15713 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00110 | 221 | 1096 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00107 | 2621 | 3094 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00050 | 5195 | 6367 | emrA | 0/0 | 100.0 | 98.3 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00050 | 3640 | 5178 | emrB | 0/0 | 100.0 | 99.9 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00001 | 284150 | 285205 | emrK | 0/0 | 100.0 | 99.2 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00050 | 6494 | 7024 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00001 | 282612 | 284150 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00003 | 120144 | 121787 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00008 | 37918 | 39111 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 164009 | 165142 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00001 | 343482 | 344786 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00008 | 127250 | 128407 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00034 | 46369 | 46701 | Escherichia_coli_emrE | 0/0 | 100.0 | 91.9 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00029 | 30138 | 31370 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00001 | 285729 | 286343 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00001 | 286348 | 289941 | evgS | 0/0 | 100.0 | 99.6 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00036 | 41068 | 41796 | gadW | 0/0 | 100.0 | 94.4 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00036 | 42164 | 42988 | gadX | 0/0 | 100.0 | 97.9 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00048 | 25271 | 25684 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00057 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00023 | 40695 | 41078 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00035 | 18809 | 20056 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00035 | 20056 | 23178 | mdtB | 0/0 | 100.0 | 99.7 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00035 | 23179 | 26256 | mdtC | 0/0 | 100.0 | 99.8 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00036 | 36410 | 37567 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00036 | 37592 | 40705 | mdtF | 0/0 | 100.0 | 98.5 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00056 | 16616 | 17842 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00005 | 2605 | 3813 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00053 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00003 | 89475 | 90506 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00003 | 87424 | 89475 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00003 | 85961 | 87427 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00111 | 2655 | 3560 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00001 | 400293 | 400767 | mphB | 0/0 | 99.6 | 97.5 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00004 | 23577 | 25325 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00122 | 578 | 1408 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00001 | 169035 | 170003 | pmrF | 0/0 | 100.0 | 99.5 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00107 | 316 | 1155 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00104 | 1718 | 2923 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00010 | 28929 | 30416 | tolC | 0/0 | 100.0 | 98.4 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 120452 | 122095 | yojI | 0/0 | 100.0 | 98.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00118 | 1695 | 2555 | (AGly)aac3-IIa | 0/0 | 100 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00107 | 1702 | 2490 | (AGly)aadA5 | 0/0 | 100 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00001 | 343482 | 344786 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 98.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00003 | 164009 | 165142 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00008 | 127250 | 128407 | (Bla)ampH_Ecoli | 0/0 | 100 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00110 | 221 | 1096 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00122 | 578 | 1408 | (Bla)blaOXA-1 | 0/0 | 100 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00015 | 30073 | 31974 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00111 | 2655 | 3560 | (MLS)mph(A) | 0/0 | 100 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00107 | 316 | 1155 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00104 | 1718 | 2923 | (Tet)tetB | 0/0 | 100 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00107 | 2621 | 3094 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00118 | 1695 | 2555 | aac(3)-IIe | 0/0 | 100 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00122 | 1539 | 2093 | aac(6’)-Ib-D181Y | 0/0 | 100 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00107 | 1702 | 2490 | aadA5 | 0/0 | 100 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00110 | 221 | 1096 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00003 | 164009 | 165142 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00122 | 578 | 1408 | blaOXA-1 | 0/0 | 100 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00107 | 2621 | 3094 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00111 | 2639 | 3560 | mph(A) | 1/1 | 100 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00107 | 316 | 1155 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00104 | 1718 | 2923 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00118 | 1695 | 2555 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00008 | 37918 | 39111 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00008 | 39134 | 42283 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00001 | 375904 | 379017 | ACRD | 0/0 | 100.0 | 98.9 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00007 | 121749 | 122906 | ACRE | 0/0 | 100.0 | 99.0 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00007 | 122918 | 126022 | ACRF | 0/0 | 100.0 | 100.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00007 | 120688 | 121350 | ACRS | 0/0 | 100.0 | 99.4 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00003 | 164009 | 165142 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00008 | 127250 | 128407 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00107 | 1702 | 2490 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00035 | 5018 | 6870 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00010 | 52778 | 53597 | BACA | 0/0 | 99.8 | 98.9 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00035 | 29069 | 29791 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00035 | 27669 | 29072 | BAES | 0/0 | 100.0 | 99.9 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 93990 | 95180 | BCR | 0/0 | 100.0 | 98.2 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00046 | 22348 | 23046 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00046 | 23043 | 24416 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00018 | 15081 | 15713 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00139 | 61 | 987 | CTX | 0/0 | 98.3 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00107 | 2621 | 3094 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00050 | 5195 | 6367 | EMRA | 0/0 | 100.0 | 98.3 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00050 | 3640 | 5178 | EMRB | 0/0 | 100.0 | 99.9 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00024 | 16466 | 17656 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00001 | 284150 | 285313 | EMRK | 0/0 | 100.0 | 99.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00050 | 6494 | 7024 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00001 | 282612 | 284150 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00003 | 120144 | 121787 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00001 | 286348 | 289941 | EVGS | 0/0 | 100.0 | 99.6 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00036 | 41068 | 41796 | GADW | 0/0 | 100.0 | 98.6 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00036 | 42164 | 42988 | GADX | 0/0 | 100.0 | 97.9 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00048 | 25271 | 25684 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00057 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00023 | 40689 | 41078 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00023 | 40241 | 40675 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00029 | 30138 | 31370 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00035 | 18809 | 20056 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00035 | 20056 | 23178 | MDTB | 0/0 | 100.0 | 99.7 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00035 | 23179 | 26256 | MDTC | 0/0 | 100.0 | 99.8 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00036 | 36410 | 37567 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00036 | 37592 | 40705 | MDTF | 0/0 | 100.0 | 98.5 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00056 | 16616 | 17842 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00005 | 2605 | 3813 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00028 | 21818 | 22147 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00028 | 22134 | 22499 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00002 | 264518 | 265891 | MDTK | 0/0 | 100.0 | 100.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00053 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00003 | 89475 | 90506 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00003 | 87424 | 89475 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00003 | 85961 | 87427 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00111 | 2639 | 3560 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00001 | 400293 | 400767 | MPHB | 0/0 | 99.6 | 97.5 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00004 | 23577 | 25325 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00034 | 46369 | 46701 | MVRC | 0/0 | 100.0 | 91.9 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00122 | 578 | 1408 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00015 | 30073 | 31974 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00001 | 343482 | 344786 | PBP4B | 0/0 | 100.0 | 98.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 169035 | 170003 | PMRF | 0/0 | 100.0 | 99.5 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00037 | 19925 | 20794 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00003 | 64021 | 64344 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00107 | 189 | 1156 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00104 | 1718 | 2923 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00104 | 3717 | 4133 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00001 | 120452 | 122095 | YOGI | 0/0 | 100.0 | 98.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00185 | 71 | 931 | blaSHV-12_1 | 0/0 | 100 | 100.0 | KF976405 | blaSHV-12 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00165 | 395 | 1255 | blaTEM-1B_1 | 0/0 | 100 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00157 | 264 | 1027 | erm(B)_18 | 2/2 | 100 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00029 | 16291 | 17523 | mdf(A)_1 | 0/0 | 100 | 98.6 | Y08743 | mdf(A) |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00003 | 80246 | 83395 | acrB | 0/0 | 100.0 | 99.3 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00030 | 37677 | 40790 | acrD | 0/0 | 100.0 | 99.3 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00013 | 79239 | 80396 | acrE | 0/0 | 100.0 | 99.1 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00013 | 80408 | 83512 | acrF | 0/0 | 100.0 | 98.5 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00013 | 78178 | 78840 | acrS | 0/0 | 100.0 | 99.1 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00009 | 69268 | 70089 | bacA | 0/0 | 100.0 | 98.4 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00011 | 80989 | 81711 | baeR | 0/0 | 100.0 | 99.5 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00011 | 79589 | 80992 | baeS | 0/0 | 100.0 | 93.9 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00008 | 8959 | 10332 | cpxA | 0/0 | 100.0 | 98.8 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00002 | 42025 | 42657 | CRP | 0/0 | 100.0 | 99.4 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00063 | 14748 | 15920 | emrA | 0/0 | 100.0 | 98.9 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00063 | 15937 | 17475 | emrB | 0/0 | 100.0 | 98.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00056 | 7518 | 8573 | emrK | 0/0 | 100.0 | 98.4 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00063 | 14091 | 14621 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00056 | 5980 | 7518 | emrY | 0/0 | 100.0 | 98.8 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00007 | 53018 | 54661 | eptA | 0/0 | 100.0 | 98.8 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00157 | 290 | 1035 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00003 | 83418 | 84611 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.9 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00007 | 96718 | 97851 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.3 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00023 | 44869 | 46173 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 96.3 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00027 | 12330 | 13487 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00029 | 16291 | 17523 | Escherichia_coli_mdfA | 0/0 | 100.0 | 97.1 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00056 | 9096 | 9710 | evgA | 0/0 | 100.0 | 99.7 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00056 | 9715 | 13308 | evgS | 0/0 | 100.0 | 97.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00028 | 35258 | 35986 | gadW | 0/0 | 100.0 | 94.9 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00028 | 34066 | 34890 | gadX | 0/0 | 100.0 | 98.1 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00024 | 24031 | 24444 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00021 | 11168 | 11845 | kdpE | 0/0 | 100.0 | 96.6 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00033 | 31485 | 31868 | marA | 0/0 | 100.0 | 99.7 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00011 | 71976 | 75098 | mdtB | 0/0 | 100.0 | 98.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00011 | 75099 | 78176 | mdtC | 0/0 | 100.0 | 98.9 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00028 | 39487 | 40644 | mdtE | 0/0 | 100.0 | 99.3 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00028 | 36349 | 39462 | mdtF | 0/0 | 100.0 | 99.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00004 | 132356 | 133582 | mdtG | 0/0 | 100.0 | 98.5 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00004 | 122517 | 123725 | mdtH | 0/0 | 100.0 | 99.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00034 | 35718 | 36950 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00007 | 19557 | 20588 | mdtN | 0/0 | 100.0 | 98.6 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00007 | 17506 | 19557 | mdtO | 0/0 | 100.0 | 97.5 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00007 | 16046 | 17509 | mdtP | 1/3 | 99.8 | 98.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00030 | 16486 | 16960 | mphB | 0/0 | 99.6 | 98.1 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00014 | 49560 | 51308 | msbA | 0/0 | 100.0 | 98.9 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00006 | 124902 | 125870 | pmrF | 0/0 | 100.0 | 98.7 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00185 | 71 | 931 | SHV-134 | 0/0 | 100.0 | 99.9 | HM559945:0-861 | SHV-134 is an extended-spectrum beta-lactamase. | carbapenem, cephalosporin, penam |
| contig00165 | 395 | 1255 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00009 | 50633 | 52120 | tolC | 0/0 | 100.0 | 98.9 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 74481 | 76124 | yojI | 0/0 | 100.0 | 99.5 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00023 | 44869 | 46173 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 96.3 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00007 | 96718 | 97851 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 98.3 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00027 | 12330 | 13487 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00185 | 71 | 931 | (Bla)blaSHV-12 | 0/0 | 100 | 100.0 | FJ685654:24-860 | (Bla)blaSHV-12 | NA |
| contig00165 | 395 | 1255 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00021 | 61939 | 63840 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 98.8 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00157 | 290 | 1027 | (MLS)erm(B) | 0/0 | 100 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00007 | 96718 | 97851 | blaEC | 0/0 | 100 | 99.1 | NG_047496.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00185 | 71 | 931 | blaSHV-12 | 0/0 | 100 | 100.0 | NG_050590.1 | class A extended-spectrum beta-lactamase SHV-12 | CEPHALOSPORIN |
| contig00165 | 395 | 1255 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00157 | 290 | 1027 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00003 | 83418 | 84611 | ACRA | 0/0 | 100.0 | 99.9 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00003 | 80246 | 83395 | ACRB | 0/0 | 100.0 | 99.3 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00030 | 37677 | 40790 | ACRD | 0/0 | 100.0 | 99.3 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00013 | 79239 | 80396 | ACRE | 0/0 | 100.0 | 99.1 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00013 | 80408 | 83512 | ACRF | 0/0 | 100.0 | 98.5 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00013 | 78178 | 78840 | ACRS | 0/0 | 100.0 | 99.1 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00027 | 12330 | 13487 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00009 | 69268 | 70089 | BACA | 0/0 | 100.0 | 98.7 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00011 | 80989 | 81711 | BAER | 0/0 | 100.0 | 99.5 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00011 | 79589 | 80992 | BAES | 0/0 | 100.0 | 93.9 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00006 | 47795 | 48985 | BCR | 0/0 | 100.0 | 97.1 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00007 | 96718 | 97851 | BLAEC | 0/0 | 100.0 | 99.1 | MEG_1276 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00008 | 8959 | 10332 | CPXAR | 0/0 | 100.0 | 98.9 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00008 | 10329 | 11027 | CPXAR | 0/0 | 100.0 | 99.7 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00002 | 42025 | 42657 | CRP | 0/0 | 100.0 | 99.4 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00063 | 14748 | 15920 | EMRA | 0/0 | 100.0 | 98.9 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00063 | 15937 | 17475 | EMRB | 0/0 | 100.0 | 98.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00037 | 29091 | 30281 | EMRD | 0/0 | 100.0 | 98.3 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00056 | 7518 | 8681 | EMRK | 0/0 | 100.0 | 98.5 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00063 | 14091 | 14621 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00056 | 5980 | 7518 | EMRY | 0/0 | 100.0 | 98.9 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00007 | 53018 | 54661 | EPTA | 0/0 | 100.0 | 98.8 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00157 | 264 | 1027 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00056 | 9715 | 13308 | EVGS | 0/0 | 100.0 | 98.8 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00028 | 35258 | 35986 | GADW | 0/0 | 100.0 | 99.2 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00028 | 34066 | 34890 | GADX | 0/0 | 100.0 | 98.1 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00024 | 24031 | 24444 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00021 | 11168 | 11845 | KDPE | 0/0 | 100.0 | 96.6 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00033 | 31479 | 31868 | MARA | 0/0 | 100.0 | 99.7 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00033 | 31030 | 31464 | MARR | 0/0 | 100.0 | 98.2 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00029 | 16291 | 17523 | MDFA | 0/0 | 100.0 | 98.7 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00011 | 71976 | 75098 | MDTB | 0/0 | 100.0 | 98.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00011 | 75099 | 78176 | MDTC | 0/0 | 100.0 | 98.9 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00028 | 39487 | 40644 | MDTE | 0/0 | 100.0 | 99.3 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00028 | 36349 | 39462 | MDTF | 0/0 | 100.0 | 99.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00004 | 132356 | 133582 | MDTG | 0/0 | 100.0 | 98.8 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00004 | 122517 | 123725 | MDTH | 0/0 | 100.0 | 99.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00068 | 1754 | 2083 | MDTI | 0/0 | 100.0 | 99.4 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00068 | 2070 | 2434 | MDTJ | 0/0 | 99.7 | 99.2 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00020 | 33769 | 35142 | MDTK | 0/0 | 100.0 | 99.4 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00034 | 35718 | 36950 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00007 | 19557 | 20588 | MDTN | 0/0 | 100.0 | 98.6 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00007 | 17506 | 19557 | MDTO | 0/0 | 100.0 | 97.5 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00007 | 16046 | 17509 | MDTP | 1/3 | 99.8 | 98.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00030 | 16486 | 16960 | MPHB | 0/0 | 99.6 | 98.1 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00014 | 49560 | 51308 | MSBA | 0/0 | 100.0 | 98.9 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00021 | 61939 | 63840 | PBP2 | 0/0 | 100.0 | 98.8 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00023 | 44869 | 46173 | PBP4B | 0/0 | 100.0 | 96.3 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00006 | 124902 | 125870 | PMRF | 0/0 | 100.0 | 98.7 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00040 | 29575 | 30444 | ROBA | 0/0 | 100.0 | 98.8 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00185 | 25 | 1028 | SHV | 0/0 | 99.7 | 98.9 | MEG_6428 | Drugs:betalactams:Class_A_betalactamases:SHV | NA |
| contig00054 | 4339 | 4661 | SOXS | 0/0 | 99.7 | 98.8 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00006 | 74481 | 76124 | YOGI | 0/0 | 100.0 | 99.5 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00112 | 1539 | 2138 | aac(6’)-Ib-cr_1 | 0/0 | 100 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00096 | 1702 | 2490 | aadA5_1 | 0/0 | 100 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00084 | 5421 | 6200 | aph(3’’)-Ib_5 | 0/0 | 97 | 100.0 | AF321551 | aph(3’’)-Ib | Streptomycin |
| contig00084 | 4585 | 5421 | aph(6)-Id_1 | 0/0 | 100 | 100.0 | M28829 | aph(6)-Id | Streptomycin |
| contig00095 | 1222 | 2097 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00112 | 578 | 1408 | blaOXA-1_1 | 0/0 | 100 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00096 | 2621 | 3094 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00005 | 64055 | 65287 | mdf(A)_1 | 0/0 | 100 | 99.9 | Y08743 | mdf(A) | |
| contig00122 | 68 | 989 | mph(A)_2 | 1/1 | 100 | 99.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00096 | 316 | 1182 | sul1_5 | 0/0 | 100 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00084 | 85 | 900 | sul2_2 | 0/0 | 100 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00087 | 1998 | 3203 | tet(B)_2 | 0/0 | 100 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00112 | 1539 | 2138 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00096 | 1702 | 2490 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00027 | 39300 | 42449 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 148083 | 151196 | acrD | 0/0 | 100.0 | 98.8 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00077 | 5525 | 8629 | acrF | 0/0 | 100.0 | 100.0 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00063 | 20452 | 21114 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00084 | 5421 | 6200 | APH(3’’)-Ib | 0/0 | 97.0 | 99.7 | AF313472:15593-16397 | APH(3’’)-Ib is an aminoglycoside phosphotransferase encoded by plasmids transposons integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp. | aminoglycoside |
| contig00084 | 4585 | 5421 | APH(6)-Id | 0/0 | 100.0 | 99.9 | AF024602:3155-3992 | APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids integrative conjugative elements and chromosomal genomic islands in K. pneumoniae Salmonella spp. E. coli Shigella flexneri Providencia alcalifaciens Pseudomonas spp. V. cholerae Edwardsiella tarda Pasteurella multocida and Aeromonas bestiarum | aminoglycoside |
| contig00010 | 70354 | 71173 | bacA | 0/0 | 99.8 | 98.5 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00026 | 57251 | 57973 | baeR | 0/0 | 100.0 | 99.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00026 | 55851 | 57254 | baeS | 0/0 | 100.0 | 98.7 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00051 | 23029 | 24402 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00095 | 1222 | 2097 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00096 | 2621 | 3094 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00007 | 58703 | 59875 | emrA | 0/0 | 100.0 | 97.9 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00007 | 59892 | 61430 | emrB | 0/0 | 100.0 | 98.6 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00001 | 270703 | 271758 | emrK | 0/0 | 100.0 | 98.0 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00007 | 58046 | 58576 | emrR | 0/0 | 100.0 | 99.4 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00001 | 269165 | 270703 | emrY | 0/0 | 100.0 | 97.7 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00060 | 7687 | 9330 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00027 | 38084 | 39277 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00038 | 29763 | 30896 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.3 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00059 | 25513 | 26811 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 99.5 | 96.1 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00018 | 65498 | 66655 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00005 | 64055 | 65287 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00001 | 272282 | 272896 | evgA | 0/0 | 100.0 | 99.2 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00001 | 272901 | 276494 | evgS | 0/0 | 100.0 | 96.8 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00043 | 2243 | 2971 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00043 | 1051 | 1875 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00039 | 5312 | 5725 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00064 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00023 | 30981 | 31364 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00026 | 46991 | 48238 | mdtA | 0/0 | 100.0 | 98.1 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00026 | 48238 | 51360 | mdtB | 0/0 | 100.0 | 99.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00026 | 51361 | 54438 | mdtC | 0/0 | 100.0 | 97.7 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00043 | 6472 | 7629 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00043 | 3334 | 6447 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00035 | 29397 | 30623 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00035 | 19561 | 20769 | mdtH | 0/0 | 100.0 | 99.9 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00036 | 28265 | 29497 | mdtM | 0/0 | 100.0 | 96.3 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00019 | 60675 | 61706 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00019 | 58624 | 60675 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00019 | 57161 | 58627 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00122 | 68 | 973 | mphA | 0/0 | 100.0 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00003 | 126902 | 127376 | mphB | 0/0 | 99.6 | 96.2 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00004 | 51374 | 53122 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00112 | 578 | 1408 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00001 | 156190 | 157158 | pmrF | 0/0 | 100.0 | 98.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00096 | 316 | 1155 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00084 | 85 | 900 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00087 | 1998 | 3203 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00010 | 46587 | 48074 | tolC | 0/0 | 100.0 | 99.9 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00001 | 94315 | 95958 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00096 | 1702 | 2490 | (AGly)aadA5 | 0/0 | 100.0 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00084 | 5421 | 6200 | (AGly)strA | 0/0 | 97.0 | 99.9 | AB366441:22458-23261 | (AGly)strA | NA |
| contig00084 | 4585 | 5421 | (AGly)strB | 0/0 | 100.0 | 100.0 | FJ474091:264-1100 | (AGly)strB | NA |
| contig00059 | 25513 | 26811 | (Bla)AmpC1_Ecoli | 0/0 | 99.5 | 96.1 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00038 | 29763 | 30896 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 97.3 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00018 | 65498 | 66655 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00095 | 1222 | 2097 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00112 | 578 | 1408 | (Bla)blaOXA-1 | 0/0 | 100.0 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00012 | 38461 | 40362 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00122 | 68 | 973 | (MLS)mph(A) | 0/0 | 100.0 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00096 | 316 | 1155 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00084 | 85 | 900 | (Sul)sul2 | 0/0 | 100.0 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00087 | 1998 | 3203 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00096 | 2621 | 3094 | (Tmt)dfrA17 | 0/0 | 100.0 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00112 | 1539 | 2093 | aac(6’)-Ib-D181Y | 0/0 | 100.0 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00096 | 1702 | 2490 | aadA5 | 0/0 | 100.0 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00084 | 5421 | 6200 | aph(3’’)-Ib | 0/0 | 94.2 | 100.0 | NG_056002.2 | aminoglycoside O-phosphotransferase APH(3’’)-Ib | STREPTOMYCIN |
| contig00084 | 4585 | 5421 | aph(6)-Id | 0/0 | 100.0 | 100.0 | NG_047464.1 | aminoglycoside O-phosphotransferase APH(6)-Id | STREPTOMYCIN |
| contig00095 | 1222 | 2097 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00038 | 29763 | 30896 | blaEC-15 | 0/0 | 100.0 | 98.5 | NG_049081.1 | class C extended-spectrum beta-lactamase EC-15 | CEPHALOSPORIN |
| contig00112 | 578 | 1408 | blaOXA-1 | 0/0 | 100.0 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00096 | 2621 | 3094 | dfrA17 | 0/0 | 100.0 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00122 | 68 | 989 | mph(A) | 1/1 | 100.0 | 99.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00096 | 316 | 1155 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00084 | 85 | 900 | sul2 | 0/0 | 100.0 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00087 | 1998 | 3203 | tet(B) | 0/0 | 100.0 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00027 | 38084 | 39277 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00027 | 39300 | 42449 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00003 | 148083 | 151196 | ACRD | 0/0 | 100.0 | 98.8 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00077 | 5525 | 8629 | ACRF | 0/0 | 100.0 | 100.0 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00063 | 20452 | 21114 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00018 | 65498 | 66655 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00096 | 1702 | 2490 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00084 | 5421 | 6200 | APH3-DPRIME | 0/0 | 94.2 | 100.0 | MEG_1019 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH3-DPRIME | NA |
| contig00084 | 4585 | 5421 | APH6 | 0/0 | 100.0 | 100.0 | MEG_1086 | Drugs:Aminoglycosides:Aminoglycoside_O-phosphotransferases:APH6 | NA |
| contig00026 | 32873 | 34725 | ASMA | 0/0 | 100.0 | 97.2 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00010 | 70354 | 71173 | BACA | 0/0 | 99.8 | 98.8 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00026 | 57251 | 57973 | BAER | 0/0 | 100.0 | 99.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00026 | 55851 | 57254 | BAES | 0/0 | 100.0 | 98.7 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00001 | 67338 | 68528 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00038 | 29763 | 30896 | BLAEC | 0/0 | 100.0 | 98.5 | MEG_1282 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00051 | 22334 | 23032 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00051 | 23029 | 24402 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 15387 | 16019 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00125 | 62 | 1004 | CTX | 0/0 | 100.0 | 98.2 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00096 | 2621 | 3094 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00007 | 58703 | 59875 | EMRA | 0/0 | 100.0 | 97.9 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00007 | 59892 | 61430 | EMRB | 0/0 | 100.0 | 98.6 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00040 | 43174 | 44364 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00001 | 270703 | 271866 | EMRK | 0/0 | 100.0 | 98.2 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00007 | 58046 | 58576 | EMRR | 0/0 | 100.0 | 99.4 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00001 | 269165 | 270703 | EMRY | 0/0 | 100.0 | 97.7 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00060 | 7687 | 9330 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00001 | 272901 | 276494 | EVGS | 0/0 | 100.0 | 97.2 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00043 | 2243 | 2971 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00043 | 1051 | 1875 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00039 | 5312 | 5725 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00064 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00023 | 30975 | 31364 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00023 | 30527 | 30961 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00005 | 64055 | 65287 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00026 | 46991 | 48238 | MDTA | 0/0 | 100.0 | 98.1 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00026 | 48238 | 51360 | MDTB | 0/0 | 100.0 | 99.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00026 | 51361 | 54438 | MDTC | 0/0 | 100.0 | 97.7 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00043 | 6472 | 7629 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00043 | 3334 | 6447 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00035 | 29397 | 30623 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00035 | 19561 | 20769 | MDTH | 0/0 | 100.0 | 99.9 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00023 | 63757 | 64086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00023 | 64073 | 64438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00014 | 26477 | 27850 | MDTK | 0/0 | 100.0 | 100.0 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00036 | 28265 | 29497 | MDTM | 0/0 | 100.0 | 96.3 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00019 | 60675 | 61706 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00019 | 58624 | 60675 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00019 | 57161 | 58627 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00122 | 68 | 989 | MPHA | 1/1 | 100.0 | 99.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00003 | 126902 | 127376 | MPHB | 0/0 | 99.6 | 96.2 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00004 | 51374 | 53122 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00112 | 578 | 1408 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00012 | 38461 | 40362 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00059 | 25513 | 26811 | PBP4B | 0/0 | 99.5 | 96.1 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00001 | 156190 | 157158 | PMRF | 0/0 | 100.0 | 98.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00045 | 21724 | 22593 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00019 | 35222 | 35545 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00096 | 189 | 1156 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00084 | 85 | 900 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00087 | 1998 | 3203 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00087 | 3997 | 4413 | TETD | 0/0 | 100.0 | 100.0 | MEG_7070 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETD | NA |
| contig00001 | 94315 | 95958 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00122 | 5182 | 6042 | aac(3)-IIa_1 | 0/0 | 100.0 | 100.0 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00122 | 9866 | 10741 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00137 | 9040 | 9906 | blaSHV-187_1 | 0/0 | 100.0 | 99.5 | LN515533 | blaSHV-187 | |
| contig00122 | 6184 | 7044 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00233 | 425 | 1084 | catA1_1 | 0/0 | 100.0 | 99.8 | V00622 | catA1 | Chloramphenicol |
| contig00202 | 4742 | 5315 | dfrA7_5 | 3/4 | 100.0 | 98.8 | AJ419170 | dfrA7 | Trimethoprim |
| contig00075 | 12852 | 13271 | fosA_3 | 0/0 | 100.0 | 99.8 | ACWO01000079 | fosA | Fosfomycin |
| contig00017 | 10037 | 11212 | oqxA_1 | 0/0 | 100.0 | 99.4 | EU370913 | oqxA | Nalidixic_acid, Ciprofloxacin |
| contig00017 | 6861 | 10013 | oqxB_1 | 0/0 | 100.0 | 99.2 | EU370913 | oqxB | Nalidixic_acid, Ciprofloxacin |
| contig00202 | 3432 | 4298 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00257 | 860 | 2106 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00122 | 5182 | 6042 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00233 | 425 | 1084 | catI | 0/0 | 100.0 | 99.8 | V00622:243-903 | catI is a chromosome and transposon-encoded variant of the cat gene found in Escherichia coli and Acinetobacter baumannii | phenicol |
| contig00122 | 9866 | 10741 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00202 | 4842 | 5315 | dfrA7 | 0/0 | 100.0 | 100.0 | FJ854362:2338-2812 | dfrA7 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00075 | 12852 | 13271 | FosA6 | 0/0 | 100.0 | 99.5 | KU254579.1:59421-59841 | fosA6 is a plasmid-encoded enzyme that confers resistance to fosfomycin in Escherichia coli by breaking the epoxide ring of the molecule. | fosfomycin |
| contig00010 | 8294 | 9487 | Klebsiella_pneumoniae_acrA | 2/3 | 99.8 | 97.7 | AJ318073.1:793-1990 | AcrA is a subunit of the AcrAB multidrug efflux system that in K. pneumoniae which is encoded by the acrRAB operon. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00063 | 3564 | 3926 | Klebsiella_pneumoniae_KpnE | 0/0 | 100.0 | 99.2 | AP006725.1:2483889-2484252 | KpnE subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime ceftriaxon colistin erythromycin rifampin tetracycline and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate deoxycholate dyes benzalkonium chloride chlorhexidine and triclosan | aminoglycoside, cephalosporin, macrolide, peptide, rifamycin, tetracycline |
| contig00063 | 3913 | 4242 | Klebsiella_pneumoniae_KpnF | 0/0 | 100.0 | 100.0 | AP006725.1:2484238-2484568 | KpnF subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime ceftriaxon colistin erythromycin rifampin tetracycline and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate deoxycholate dyes benzalkonium chloride chlorhexidine and triclosan. | aminoglycoside, cephalosporin, macrolide, peptide, rifamycin, tetracycline |
| contig00113 | 10340 | 11512 | Klebsiella_pneumoniae_KpnG | 0/0 | 100.0 | 99.3 | ACWO01000051.1:22092-23265 | KpnG consists of ~390 residues and resembles EmrA of E. coli. Disruption of the pump components KpnG-KpnH signficantly decrease resistance to azithromycin ceftazidime ciprofloxacin ertapenem erythromycin gentamicin imipenem ticarcillin norfloxacin polymyxin-B piperacillin spectinomycin tobramycin and streptomycin | aminoglycoside, carbapenem, cephalosporin, fluoroquinolone, macrolide, penam, penem, peptide |
| contig00059 | 13299 | 14453 | Klebsiella_pneumoniae_OmpK37 | 7/32 | 99.9 | 95.2 | AJ011502.1:300-1425 | Klebsiella pneumoniae outer membrane porin protein. Is preferentially detected in porin-deficient strains. Functional characterization of this new porin revealed a narrower pore than those of porins OmpK35 and OmpK36 which did not allow penetration by certain beta-lactams. Also when a resistant strain expresses porin OmpK37 is less susceptible to cefotaxime and cefoxitin than when it is expressing either OmpK36 or OmpK35. | carbapenem, cephalosporin, cephamycin, monobactam, penam, penem |
| contig00017 | 10037 | 11212 | oqxA | 0/0 | 100.0 | 99.4 | EU370913.1:46651-47827 | RND efflux pump conferring resistance to fluoroquinolone | diaminopyrimidine, fluoroquinolone, glycylcycline, nitrofuran, tetracycline |
| contig00017 | 6861 | 10013 | oqxB | 0/0 | 100.0 | 99.2 | EU370913.1:47850-51003 | RND efflux pump conferring resistance to fluoroquinolone | diaminopyrimidine, fluoroquinolone, glycylcycline, nitrofuran, tetracycline |
| contig00137 | 9040 | 9906 | SHV-187 | 0/0 | 100.0 | 99.5 | LN515533:0-867 | From the Lahey list of beta-lactamases. | carbapenem, cephalosporin, penam |
| contig00202 | 3432 | 4271 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00122 | 6184 | 7044 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00257 | 860 | 2106 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00122 | 5182 | 6042 | (AGly)aac3-IIa | 0/0 | 100 | 100.0 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00053 | 18628 | 19788 | (Bla)ampH | 0/0 | 100 | 99.9 | CP003785:4208384-4209544 | (Bla)ampH | NA |
| contig00122 | 9866 | 10741 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00137 | 9040 | 9906 | (Bla)blaSHV-187 | 0/0 | 100 | 99.5 | LN515533:1-867 | (Bla)blaSHV-187 | NA |
| contig00122 | 6184 | 7044 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00075 | 12852 | 13271 | (Fcyn)FosA6 | 0/0 | 100 | 99.5 | KU254579:59422-59841 | (Fcyn)FosA6 | NA |
| contig00017 | 10037 | 11212 | (Flq)OqxA | 0/0 | 100 | 99.4 | EU370913:46652-47827 | (Flq)OqxA | NA |
| contig00017 | 6861 | 10013 | (Flq)OqxBgb | 0/0 | 100 | 99.2 | EU370913:47851-51003 | (Flq)OqxBgb | NA |
| contig00233 | 425 | 1084 | (Phe)catA1 | 0/0 | 100 | 99.8 | V00622:244-903 | (Phe)catA1 | NA |
| contig00202 | 3432 | 4271 | (Sul)sul1 | 0/0 | 100 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00257 | 860 | 2134 | (Tet)tetA | 0/0 | 100 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00257 | 179 | 829 | (Tet)tetR | 0/0 | 100 | 100.0 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00202 | 4842 | 5315 | (Tmt)dhfr7 | 0/0 | 100 | 100.0 | X58425:594-1067 | (Tmt)dhfr7 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00122 | 5182 | 6042 | aac(3)-IIe | 0/0 | 100 | 100.0 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00122 | 9866 | 10741 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00137 | 9040 | 9906 | blaSHV-187 | 0/0 | 100 | 99.5 | NG_050053.1 | class A beta-lactamase SHV-187 | BETA-LACTAM |
| contig00122 | 6184 | 7044 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00233 | 425 | 1084 | catA1 | 0/0 | 100 | 99.8 | NG_047582.1 | type A-1 chloramphenicol O-acetyltransferase | CHLORAMPHENICOL |
| contig00202 | 4842 | 5315 | dfrA7 | 0/0 | 100 | 100.0 | NG_047737.1 | trimethoprim-resistant dihydrofolate reductase DfrA7 | TRIMETHOPRIM |
| contig00075 | 12852 | 13271 | fosA_gen | 0/0 | 100 | 99.8 | NG_047884.1 | FosA family fosfomycin resistance glutathione transferase | FOSFOMYCIN |
| contig00017 | 10037 | 11212 | oqxA10 | 0/0 | 100 | 99.8 | NG_050418.1 | multidrug efflux RND transporter periplasmic adaptor subunit OqxA10 | PHENICOL, QUINOLONE |
| contig00017 | 6861 | 10013 | oqxB32 | 0/0 | 100 | 100.0 | NG_050452.1 | multidrug efflux RND transporter permease subunit OqxB32 | PHENICOL, QUINOLONE |
| contig00202 | 3432 | 4271 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00257 | 935 | 2134 | tet(A) | 0/0 | 100 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00122 | 5182 | 6042 | AAC3 | 0/0 | 100.0 | 100.0 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00010 | 8294 | 9487 | ACRA | 2/3 | 99.8 | 97.7 | MEG_400 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00053 | 18628 | 19788 | AMPH | 0/0 | 100.0 | 99.9 | MEG_730 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00247 | 1749 | 3572 | ASMA | 0/0 | 100.0 | 99.3 | MEG_1179 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00233 | 414 | 1084 | CATA | 0/0 | 100.0 | 100.0 | MEG_1593 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00005 | 22585 | 23283 | CPXAR | 0/0 | 100.0 | 99.6 | MEG_2116 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00005 | 23280 | 24653 | CPXAR | 0/0 | 100.0 | 99.1 | MEG_2115 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00202 | 4842 | 5315 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2548 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00075 | 12852 | 13271 | FOSA | 0/0 | 100.0 | 99.8 | MEG_2993 | Drugs:Fosfomycin:Fosfomycin_thiol_transferases:FOSA | NA |
| contig00048 | 11011 | 12243 | KDEA | 0/0 | 100.0 | 100.0 | MEG_3447 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:KDEA | NA |
| contig00067 | 11440 | 12939 | KMRA | 0/0 | 100.0 | 99.3 | MEG_3460 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:KMRA | NA |
| contig00113 | 10340 | 11512 | KPN | 0/0 | 100.0 | 99.3 | MEG_3512 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:KPN | NA |
| contig00063 | 3564 | 3926 | KPNE | 0/0 | 100.0 | 99.2 | MEG_3514 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:KPNE | NA |
| contig00063 | 3913 | 4242 | KPNF | 0/0 | 100.0 | 100.0 | MEG_3515 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:KPNF | NA |
| contig00082 | 19762 | 20865 | KPNO | 4/18 | 99.5 | 95.3 | MEG_3516 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:KPNO | NA |
| contig00059 | 13299 | 14453 | OMP37 | 7/32 | 99.9 | 95.2 | MEG_4283 | Drugs:betalactams:Mutant_porin_proteins:OMP37 | NA |
| contig00017 | 10037 | 11212 | OQXA | 0/0 | 100.0 | 99.8 | MEG_4326 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:OQXA | NA |
| contig00017 | 6861 | 10013 | OQXB | 0/0 | 100.0 | 100.0 | MEG_4339 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:OQXB | NA |
| contig00021 | 40562 | 42028 | PHOR | 0/0 | 100.0 | 99.8 | MEG_5786 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_regulator:PHOR | NA |
| contig00137 | 9000 | 10003 | SHV | 0/0 | 99.7 | 98.9 | MEG_6428 | Drugs:betalactams:Class_A_betalactamases:SHV | NA |
| contig00202 | 3305 | 4272 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00122 | 6166 | 7411 | TEM | 0/0 | 98.3 | 99.3 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00257 | 860 | 2134 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00268 | 1694 | 2554 | aac(3)-IIa_1 | 0/0 | 100.0 | 99.8 | X51534 | aac(3)-IIa | Gentamicin, Tobramycin |
| contig00299 | 1540 | 2139 | aac(6’)-Ib-cr_1 | 0/0 | 100.0 | 100.0 | DQ303918 | aac(6’)-Ib-cr | Ciprofloxacin |
| contig00137 | 1442 | 2230 | aadA5_1 | 0/0 | 100.0 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00259 | 1703 | 2578 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00299 | 579 | 1409 | blaOXA-1_1 | 0/0 | 100.0 | 100.0 | HQ170510 | blaOXA-1 | Amoxicillin, Amoxicillin+Clavulanic_acid, Ampicillin, Ampicillin+Clavulanic_acid, Cefepime, Piperacillin, Piperacillin+Tazobactam |
| contig00122 | 49 | 909 | blaTEM-1B_1 | 0/0 | 100.0 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00176 | 223 | 882 | catA1_1 | 0/0 | 100.0 | 99.8 | V00622 | catA1 | Chloramphenicol |
| contig00137 | 838 | 1311 | dfrA17_1 | 0/0 | 100.0 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00006 | 41013 | 42245 | mdf(A)_1 | 0/0 | 100.0 | 98.3 | Y08743 | mdf(A) | |
| contig00515 | 67 | 959 | mph(A)_1 | 0/0 | 98.6 | 100.0 | D16251 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00137 | 2750 | 3616 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00208 | 1712 | 2958 | tet(A)_6 | 0/0 | 97.8 | 100.0 | AF534183 | tet(A) | Doxycycline, Tetracycline |
| contig00198 | 849 | 2054 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00268 | 1694 | 2554 | AAC(3)-IIe | 0/0 | 100.0 | 99.5 | EU022315.1:0-861 | AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli | aminoglycoside |
| contig00299 | 1540 | 2139 | AAC(6’)-Ib-cr | 0/0 | 100.0 | 100.0 | DQ303918:0-600 | AAC(6’)-Ib-cr is an aminoglycoside acetyltransferase encoded by plasmids transposons integrons in Enterobacteriaceae. The aac(6’)-Ib-cr variant gene can induce resistance against aminoglycoside and fluoroquinolone simultaneously | aminoglycoside, fluoroquinolone |
| contig00137 | 1442 | 2230 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00005 | 117721 | 120870 | acrB | 0/0 | 100.0 | 99.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00015 | 49488 | 52601 | acrD | 0/0 | 100.0 | 98.7 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00169 | 3 | 1160 | acrE | 0/0 | 100.0 | 98.2 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00169 | 1172 | 4276 | acrF | 0/0 | 100.0 | 97.5 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00009 | 354 | 1016 | acrS | 0/0 | 100.0 | 97.6 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00007 | 688 | 1507 | bacA | 0/0 | 99.8 | 97.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00173 | 3080 | 3801 | baeR | 0/0 | 99.9 | 97.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00173 | 1680 | 3083 | baeS | 0/0 | 100.0 | 92.1 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00176 | 223 | 882 | catI | 0/0 | 100.0 | 99.8 | V00622:243-903 | catI is a chromosome and transposon-encoded variant of the cat gene found in Escherichia coli and Acinetobacter baumannii | phenicol |
| contig00032 | 15958 | 16590 | CRP | 0/0 | 100.0 | 99.2 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00259 | 1703 | 2578 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00137 | 838 | 1311 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00020 | 43734 | 44906 | emrA | 0/0 | 100.0 | 98.1 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00020 | 44923 | 46461 | emrB | 0/0 | 100.0 | 98.5 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00060 | 21731 | 22786 | emrK | 0/0 | 100.0 | 96.9 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00020 | 43077 | 43607 | emrR | 0/0 | 100.0 | 99.4 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00060 | 20193 | 21731 | emrY | 0/0 | 100.0 | 98.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00037 | 10125 | 11768 | eptA | 0/0 | 100.0 | 98.2 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00005 | 120893 | 122086 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00062 | 12898 | 14031 | Escherichia_coli_ampC | 0/0 | 100.0 | 98.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00015 | 14955 | 16259 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 95.2 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00005 | 30315 | 31472 | Escherichia_coli_ampH | 0/0 | 100.0 | 97.3 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00304 | 1812 | 2140 | Escherichia_coli_emrE | 0/0 | 98.8 | 91.8 | Z11877.1:485-818 | Member of the small MDR (multidrug resistance) family of transporters, in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin, proton-dependent secondary transporter which exchanges protons for compound translocation | macrolide |
| contig00006 | 41013 | 42245 | Escherichia_coli_mdfA | 0/0 | 100.0 | 96.8 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00060 | 23309 | 23923 | evgA | 0/0 | 100.0 | 99.3 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00060 | 23928 | 27521 | evgS | 0/0 | 100.0 | 96.6 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00053 | 8537 | 9265 | gadW | 0/0 | 100.0 | 95.9 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00053 | 7344 | 8168 | gadX | 0/0 | 100.0 | 93.9 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00021 | 1492 | 1905 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00024 | 15684 | 16361 | kdpE | 0/0 | 100.0 | 95.6 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00030 | 23452 | 23835 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00372 | 1 | 1156 | mdtA | 0/0 | 92.6 | 97.4 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00053 | 12766 | 13923 | mdtE | 0/0 | 100.0 | 99.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00053 | 9628 | 12741 | mdtF | 0/0 | 100.0 | 98.4 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00023 | 35049 | 36275 | mdtG | 0/0 | 100.0 | 98.3 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00023 | 25210 | 26418 | mdtH | 0/0 | 100.0 | 98.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00068 | 25112 | 26344 | mdtM | 0/0 | 100.0 | 100.0 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00170 | 409 | 1620 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00026 | 6570 | 7601 | mdtN | 0/0 | 100.0 | 97.7 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00026 | 7601 | 9652 | mdtO | 0/0 | 100.0 | 96.6 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00026 | 9649 | 11115 | mdtP | 0/0 | 100.0 | 96.5 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00515 | 67 | 959 | mphA | 0/0 | 98.6 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00040 | 9970 | 10444 | mphB | 0/0 | 99.6 | 96.2 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00010 | 26429 | 28177 | msbA | 0/0 | 100.0 | 98.9 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00299 | 579 | 1409 | OXA-1 | 0/0 | 100.0 | 100.0 | JN420336.1:2230-1399 | OXA-1 is a beta-lactamase found in E. coli | cephalosporin, penam |
| contig00019 | 1874 | 2842 | pmrF | 0/0 | 100.0 | 97.9 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00137 | 2777 | 3616 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00122 | 49 | 909 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00208 | 1712 | 2958 | tet(A) | 0/0 | 97.8 | 100.0 | AF534183.1:2970-4245 | TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria. | tetracycline |
| contig00198 | 849 | 2054 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00065 | 22270 | 23757 | tolC | 0/0 | 100.0 | 97.9 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00152 | 1991 | 3157 | ugd | 0/0 | 100.0 | 96.9 | U00096:2099613-2098446 | PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin | peptide |
| contig00017 | 29227 | 30870 | yojI | 0/0 | 100.0 | 97.8 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00268 | 1694 | 2554 | (AGly)aac3-IIa | 0/0 | 100.0 | 99.8 | X51534:91-951 | (AGly)aac3-IIa | NA |
| contig00137 | 1442 | 2230 | (AGly)aadA5 | 0/0 | 100.0 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00015 | 14955 | 16259 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 95.2 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00062 | 12898 | 14031 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 98.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00005 | 30315 | 31472 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 97.3 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00259 | 1703 | 2578 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00299 | 579 | 1409 | (Bla)blaOXA-1 | 0/0 | 100.0 | 100.0 | JQ682867:1-831 | (Bla)blaOXA-1 | NA |
| contig00122 | 49 | 909 | (Bla)blaTEM-105 | 0/0 | 100.0 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00061 | 4963 | 6864 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 98.4 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00515 | 67 | 959 | (MLS)mph(A) | 0/0 | 98.6 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00176 | 223 | 882 | (Phe)catA1 | 0/0 | 100.0 | 99.8 | V00622:244-903 | (Phe)catA1 | NA |
| contig00137 | 2777 | 3616 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00208 | 1684 | 2958 | (Tet)tetA | 0/0 | 100.0 | 100.0 | JX424423:94438-95712 | (Tet)tetA | NA |
| contig00198 | 849 | 2054 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00208 | 2989 | 3639 | (Tet)tetR | 0/0 | 100.0 | 100.0 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00137 | 838 | 1311 | (Tmt)dfrA17 | 0/0 | 100.0 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00268 | 1694 | 2554 | aac(3)-IIe | 0/0 | 100.0 | 99.8 | NG_047244.1 | aminoglycoside N-acetyltransferase AAC(3)-IIe | GENTAMICIN |
| contig00299 | 1540 | 2094 | aac(6’)-Ib-D181Y | 0/0 | 100.0 | 99.8 | NG_067946.1 | AAC(6’)-Ib family aminoglycoside 6’-N-acetyltransferase | AMIKACIN, KANAMYCIN, TOBRAMYCIN |
| contig00137 | 1442 | 2230 | aadA5 | 0/0 | 100.0 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00259 | 1703 | 2578 | blaCTX-M-15 | 0/0 | 100.0 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00062 | 12898 | 14031 | blaEC-19 | 0/0 | 100.0 | 99.8 | NG_049084.1 | class C extended-spectrum beta-lactamase EC-19 | CEPHALOSPORIN |
| contig00299 | 579 | 1409 | blaOXA-1 | 0/0 | 100.0 | 100.0 | NG_049392.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | CEPHALOSPORIN |
| contig00122 | 49 | 909 | blaTEM-1 | 0/0 | 100.0 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00176 | 223 | 882 | catA1 | 0/0 | 100.0 | 99.8 | NG_047582.1 | type A-1 chloramphenicol O-acetyltransferase | CHLORAMPHENICOL |
| contig00137 | 838 | 1311 | dfrA17 | 0/0 | 100.0 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00515 | 67 | 959 | mph(A) | 0/0 | 98.6 | 100.0 | NG_047985.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00137 | 2777 | 3616 | sul1 | 0/0 | 100.0 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00208 | 1684 | 2883 | tet(A) | 0/0 | 100.0 | 100.0 | NG_048154.1 | tetracycline efflux MFS transporter Tet(A) | TETRACYCLINE |
| contig00198 | 849 | 2054 | tet(B) | 0/0 | 100.0 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00268 | 1694 | 2554 | AAC3 | 0/0 | 100.0 | 99.8 | MEG_44 | Drugs:Aminoglycosides:Aminoglycoside_N-acetyltransferases:AAC3 | NA |
| contig00005 | 120893 | 122086 | ACRA | 0/0 | 100.0 | 99.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00005 | 117721 | 120870 | ACRB | 0/0 | 100.0 | 99.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00015 | 49488 | 52601 | ACRD | 0/0 | 100.0 | 98.7 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00169 | 3 | 1160 | ACRE | 0/0 | 100.0 | 98.2 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00169 | 1172 | 4276 | ACRF | 0/0 | 100.0 | 97.5 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00009 | 354 | 1016 | ACRS | 0/0 | 100.0 | 97.6 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00005 | 30315 | 31472 | AMPH | 0/0 | 100.0 | 97.3 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00137 | 1442 | 2230 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00007 | 688 | 1507 | BACA | 0/0 | 99.8 | 97.2 | MEG_1189 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00173 | 3080 | 3801 | BAER | 0/0 | 99.9 | 97.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00173 | 1680 | 3083 | BAES | 0/0 | 100.0 | 92.1 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00017 | 2764 | 3954 | BCR | 0/0 | 100.0 | 96.6 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00062 | 12898 | 14031 | BLAEC | 0/0 | 100.0 | 99.8 | MEG_1277 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00176 | 212 | 882 | CATA | 0/0 | 100.0 | 100.0 | MEG_1593 | Drugs:Phenicol:Chloramphenicol_acetyltransferases:CATA | NA |
| contig00236 | 1264 | 1962 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00032 | 15958 | 16590 | CRP | 0/0 | 100.0 | 99.2 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00259 | 1454 | 2682 | CTX | 0/0 | 100.0 | 99.9 | MEG_2393 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00137 | 838 | 1311 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00020 | 43734 | 44906 | EMRA | 0/0 | 100.0 | 98.1 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00020 | 44923 | 46461 | EMRB | 0/0 | 100.0 | 98.5 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00057 | 18757 | 19947 | EMRD | 0/0 | 100.0 | 97.8 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00060 | 21731 | 22894 | EMRK | 0/0 | 100.0 | 96.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00020 | 43077 | 43607 | EMRR | 0/0 | 100.0 | 99.4 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00060 | 20193 | 21731 | EMRY | 0/0 | 100.0 | 98.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00037 | 10125 | 11768 | EPTA | 0/0 | 100.0 | 98.2 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00060 | 23928 | 27521 | EVGS | 0/0 | 100.0 | 97.1 | MEG_2869 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00053 | 8537 | 9265 | GADW | 0/0 | 100.0 | 97.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00053 | 7344 | 8168 | GADX | 0/0 | 100.0 | 93.9 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00021 | 1492 | 1905 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00024 | 15684 | 16361 | KDPE | 0/0 | 100.0 | 95.6 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00030 | 23446 | 23835 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00030 | 22997 | 23431 | MARR | 0/0 | 100.0 | 98.6 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00006 | 41013 | 42245 | MDFA | 0/0 | 100.0 | 98.4 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00372 | 1 | 1156 | MDTA | 0/0 | 92.6 | 97.4 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00053 | 12766 | 13923 | MDTE | 0/0 | 100.0 | 99.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00053 | 9628 | 12741 | MDTF | 0/0 | 100.0 | 98.4 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00023 | 35049 | 36275 | MDTG | 0/0 | 100.0 | 98.7 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00023 | 25210 | 26418 | MDTH | 0/0 | 100.0 | 98.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00004 | 127847 | 128176 | MDTI | 0/0 | 100.0 | 99.7 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00004 | 127495 | 127860 | MDTJ | 0/0 | 100.0 | 98.6 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00004 | 60494 | 61866 | MDTK | 0/0 | 99.9 | 97.9 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00068 | 25112 | 26344 | MDTM | 0/0 | 100.0 | 100.0 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00170 | 409 | 1620 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00026 | 6570 | 7601 | MDTN | 0/0 | 100.0 | 97.7 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00026 | 7601 | 9652 | MDTO | 0/0 | 100.0 | 96.6 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00026 | 9649 | 11115 | MDTP | 0/0 | 100.0 | 96.5 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00515 | 67 | 959 | MPHA | 0/0 | 98.6 | 100.0 | MEG_4029 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00040 | 9970 | 10444 | MPHB | 0/0 | 99.6 | 96.2 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00010 | 26429 | 28177 | MSBA | 0/0 | 100.0 | 98.9 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00304 | 1812 | 2140 | MVRC | 0/0 | 98.8 | 91.8 | MEG_4103 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MVRC | NA |
| contig00299 | 579 | 1409 | OXA | 0/0 | 100.0 | 100.0 | MEG_4980 | Drugs:betalactams:Class_D_betalactamases:OXA | NA |
| contig00061 | 4963 | 6864 | PBP2 | 0/0 | 100.0 | 98.4 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00015 | 14955 | 16259 | PBP4B | 0/0 | 100.0 | 95.2 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00019 | 1874 | 2842 | PMRF | 0/0 | 100.0 | 97.9 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00026 | 31316 | 31638 | SOXS | 0/0 | 99.7 | 97.8 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00137 | 2776 | 3743 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00208 | 1684 | 2958 | TETA | 0/0 | 100.0 | 100.0 | MEG_7024 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETA | NA |
| contig00198 | 849 | 2054 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00152 | 1991 | 3157 | UGD | 0/0 | 100.0 | 96.9 | MEG_7328 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:UGD | NA |
| contig00017 | 29227 | 30870 | YOGI | 0/0 | 100.0 | 97.8 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00110 | 137 | 925 | aadA5_1 | 0/0 | 100 | 100.0 | AF137361 | aadA5 | Streptomycin |
| contig00013 | 67769 | 68644 | blaCTX-M-15_1 | 0/0 | 100 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00075 | 8178 | 9038 | blaTEM-1B_1 | 0/0 | 100 | 100.0 | AY458016 | blaTEM-1B | Amoxicillin, Ampicillin, Cephalothin, Piperacillin, Ticarcillin |
| contig00107 | 182 | 664 | dfrA14_5 | 0/0 | 100 | 99.6 | DQ388123 | dfrA14 | Trimethoprim |
| contig00110 | 1056 | 1529 | dfrA17_1 | 0/0 | 100 | 100.0 | FJ460238 | dfrA17 | Trimethoprim |
| contig00003 | 102470 | 103702 | mdf(A)_1 | 0/0 | 100 | 99.0 | Y08743 | mdf(A) | |
| contig00075 | 2160 | 2816 | qnrS1_1 | 0/0 | 100 | 100.0 | AB187515 | qnrS1 | Ciprofloxacin |
| contig00088 | 3459 | 4274 | sul2_2 | 0/0 | 100 | 100.0 | AY034138 | sul2 | Sulfamethoxazole |
| contig00075 | 9296 | 10087 | sul3_2 | 0/0 | 100 | 100.0 | AJ459418 | sul3 | Sulfamethoxazole |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00110 | 137 | 925 | aadA5 | 0/0 | 100.0 | 100.0 | AF137361:63-852 | aadA5 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids transposons and integrons in E. coli K. pneumoniae Kluyvera georgiana P. aeruginosa and E. cloacae | aminoglycoside |
| contig00014 | 38756 | 41905 | acrB | 0/0 | 100.0 | 99.5 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00002 | 135389 | 138502 | acrD | 0/0 | 100.0 | 99.3 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00016 | 65943 | 66764 | bacA | 0/0 | 100.0 | 100.0 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00007 | 128547 | 129269 | baeR | 0/0 | 100.0 | 100.0 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00007 | 127147 | 128550 | baeS | 0/0 | 100.0 | 99.9 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00020 | 7847 | 9220 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00009 | 176 | 808 | CRP | 0/0 | 100.0 | 99.8 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00013 | 67769 | 68644 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00107 | 182 | 664 | dfrA14 | 0/0 | 100.0 | 99.8 | EU780012:2162-2645 | dfrA14 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00110 | 1056 | 1529 | dfrA17 | 0/0 | 100.0 | 100.0 | DQ838665:0-474 | dfrA17 is an integron-encoded dihydrofolate reductase found in Escherichia coli | diaminopyrimidine |
| contig00015 | 23952 | 25124 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00015 | 25141 | 26679 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00006 | 10434 | 11489 | emrK | 0/0 | 100.0 | 99.8 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00015 | 23295 | 23825 | emrR | 0/0 | 100.0 | 100.0 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00006 | 11489 | 13027 | emrY | 0/0 | 100.0 | 99.0 | D78168:1591-3130 | emrY is a multidrug transport that moves substrates across the inner membrane of the Gram-negative E. coli. It is a homolog of emrB. | tetracycline |
| contig00024 | 7727 | 9370 | eptA | 0/0 | 100.0 | 99.5 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00014 | 37540 | 38733 | Escherichia_coli_acrA | 0/0 | 100.0 | 99.5 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00024 | 51583 | 52716 | Escherichia_coli_ampC | 0/0 | 100.0 | 97.4 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00002 | 169833 | 171137 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 98.7 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00059 | 15203 | 16360 | Escherichia_coli_ampH | 0/0 | 100.0 | 98.9 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00003 | 102470 | 103702 | Escherichia_coli_mdfA | 0/0 | 100.0 | 97.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00006 | 9296 | 9910 | evgA | 0/0 | 100.0 | 100.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00006 | 5698 | 9291 | evgS | 0/0 | 100.0 | 100.0 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00038 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00038 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00087 | 938 | 1351 | H-NS | 0/0 | 100.0 | 99.5 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00023 | 8068 | 8745 | kdpE | 0/0 | 100.0 | 99.4 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00027 | 44430 | 44813 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00007 | 118287 | 119534 | mdtA | 0/0 | 100.0 | 100.0 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00007 | 119534 | 122656 | mdtB | 0/0 | 100.0 | 98.9 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00007 | 122657 | 125734 | mdtC | 0/0 | 100.0 | 99.8 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00038 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 99.7 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00038 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 99.9 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00001 | 138913 | 140139 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00001 | 148768 | 149976 | mdtH | 0/0 | 100.0 | 98.3 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00072 | 465 | 1676 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00019 | 71052 | 72083 | mdtN | 0/0 | 100.0 | 99.5 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00019 | 69001 | 71052 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00019 | 67538 | 69004 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00002 | 114229 | 114705 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00001 | 2196 | 3944 | msbA | 0/0 | 100.0 | 99.9 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00006 | 110978 | 111946 | pmrF | 0/0 | 100.0 | 99.9 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00075 | 2160 | 2816 | QnrS1 | 0/0 | 100.0 | 100.0 | DQ485529.1:0-657 | QnrS1 is a plasmid-mediated quinolone resistance protein found in Shigella flexneri | fluoroquinolone |
| contig00088 | 3459 | 4274 | sul2 | 0/0 | 100.0 | 100.0 | AY055428.1:21084-20268 | Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria usually found on small plasmids. | sulfonamide |
| contig00075 | 9296 | 10087 | sul3 | 0/0 | 100.0 | 100.0 | FJ196385:9323-8531 | Sul3 is a sulfonamide resistant dihydropteroate synthase similar to Sul1 and Sul2. Its resistance gene was found encoded in E. coli plasmid DNA of sulfonamide resistant isolates. | sulfonamide |
| contig00075 | 8178 | 9038 | TEM-1 | 0/0 | 100.0 | 99.9 | AL513383:161910-162771 | TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins. | cephalosporin, monobactam, penam, penem |
| contig00016 | 42080 | 43567 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00051 | 22605 | 24248 | yojI | 0/0 | 100.0 | 99.9 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00110 | 137 | 925 | (AGly)aadA5 | 0/0 | 100 | 100.0 | AF137361:64-852 | (AGly)aadA5 | NA |
| contig00002 | 169833 | 171137 | (Bla)AmpC1_Ecoli | 0/0 | 100 | 98.7 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00024 | 51583 | 52716 | (Bla)AmpC2_Ecoli | 0/0 | 100 | 97.4 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00059 | 15203 | 16360 | (Bla)ampH_Ecoli | 0/0 | 100 | 98.9 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00013 | 67769 | 68644 | (Bla)blaCTX-M-15 | 0/0 | 100 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00075 | 8178 | 9038 | (Bla)blaTEM-105 | 0/0 | 100 | 99.9 | AF516720:215-1075 | (Bla)blaTEM-105 | NA |
| contig00023 | 60539 | 62440 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100 | 99.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00075 | 2160 | 2816 | (Flq)qnr-S1 | 0/0 | 100 | 100.0 | AB187515:9737-10393 | (Flq)qnr-S1 | NA |
| contig00088 | 3459 | 4274 | (Sul)sul2 | 0/0 | 100 | 100.0 | EU360945:1617-2432 | (Sul)sul2 | NA |
| contig00075 | 9296 | 10087 | (Sul)sul3 | 0/0 | 100 | 100.0 | HQ875016:7396-8187 | (Sul)sul3 | NA |
| contig00114 | 172 | 822 | (Tet)tetR | 0/0 | 100 | 99.8 | HF545434:53576-54226 | (Tet)tetR | NA |
| contig00107 | 182 | 655 | (Tmt)dfrA14 | 0/0 | 100 | 100.0 | GU726917:72-545 | (Tmt)dfrA14 | NA |
| contig00110 | 1056 | 1529 | (Tmt)dfrA17 | 0/0 | 100 | 100.0 | AB126604:98-571 | (Tmt)dfrA17 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00110 | 137 | 925 | aadA5 | 0/0 | 100 | 100.0 | NG_047357.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA5 | STREPTOMYCIN |
| contig00013 | 67769 | 68644 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00024 | 51583 | 52716 | blaEC | 0/0 | 100 | 98.2 | NG_047496.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00075 | 8178 | 9038 | blaTEM-1 | 0/0 | 100 | 100.0 | NG_050145.1 | class A broad-spectrum beta-lactamase TEM-1 | BETA-LACTAM |
| contig00107 | 182 | 655 | dfrA14 | 0/0 | 100 | 100.0 | NG_056035.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | TRIMETHOPRIM |
| contig00110 | 1056 | 1529 | dfrA17 | 0/0 | 100 | 99.8 | NG_047710.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | TRIMETHOPRIM |
| contig00075 | 2160 | 2816 | qnrS1 | 0/0 | 100 | 100.0 | NG_050543.1 | quinolone resistance pentapeptide repeat protein QnrS1 | QUINOLONE |
| contig00088 | 3459 | 4274 | sul2 | 0/0 | 100 | 100.0 | NG_051852.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | SULFONAMIDE |
| contig00075 | 9296 | 10087 | sul3 | 0/0 | 100 | 100.0 | NG_048120.1 | sulfonamide-resistant dihydropteroate synthase Sul3 | SULFONAMIDE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00014 | 37540 | 38733 | ACRA | 0/0 | 100.0 | 99.5 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00014 | 38756 | 41905 | ACRB | 0/0 | 100.0 | 99.5 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00002 | 135389 | 138502 | ACRD | 0/0 | 100.0 | 99.3 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00059 | 15203 | 16360 | AMPH | 0/0 | 100.0 | 98.9 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00110 | 137 | 925 | ANT3-DPRIME | 0/0 | 100.0 | 100.0 | MEG_928 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00007 | 104022 | 105874 | ASMA | 0/0 | 100.0 | 98.0 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00016 | 65943 | 66764 | BACA | 0/0 | 100.0 | 100.0 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00007 | 128547 | 129269 | BAER | 0/0 | 100.0 | 100.0 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00007 | 127147 | 128550 | BAES | 0/0 | 100.0 | 99.9 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00042 | 14113 | 15303 | BCR | 0/0 | 100.0 | 100.0 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00024 | 51583 | 52716 | BLAEC | 0/0 | 100.0 | 98.2 | MEG_1276 | Drugs:betalactams:Class_C_betalactamases:BLAEC | NA |
| contig00020 | 7152 | 7850 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2118 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00020 | 7847 | 9220 | CPXAR | 0/0 | 100.0 | 99.4 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00009 | 176 | 808 | CRP | 0/0 | 100.0 | 99.8 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00095 | 329 | 1217 | CTX | 0/0 | 100.0 | 95.4 | MEG_2430 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00095 | 2404 | 3262 | CTX | 0/0 | 96.6 | 99.7 | MEG_2430 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00107 | 182 | 655 | DFRA | 0/0 | 100.0 | 99.8 | MEG_2517 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00110 | 1056 | 1529 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2547 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00015 | 23952 | 25124 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00015 | 25141 | 26679 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00017 | 16747 | 17937 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00006 | 10326 | 11489 | EMRK | 0/0 | 100.0 | 99.8 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00015 | 23295 | 23825 | EMRR | 0/0 | 100.0 | 100.0 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00006 | 11489 | 13027 | EMRY | 0/0 | 100.0 | 99.1 | MEG_2736 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRY | NA |
| contig00024 | 7727 | 9370 | EPTA | 0/0 | 100.0 | 99.5 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00006 | 5698 | 9291 | EVGS | 0/0 | 100.0 | 100.0 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00038 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00038 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00087 | 938 | 1351 | HNS | 0/0 | 100.0 | 99.5 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00023 | 8068 | 8745 | KDPE | 0/0 | 100.0 | 99.4 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00027 | 44424 | 44813 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00027 | 43976 | 44410 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00003 | 102470 | 103702 | MDFA | 0/0 | 100.0 | 99.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00007 | 118287 | 119534 | MDTA | 0/0 | 100.0 | 100.0 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00007 | 119534 | 122656 | MDTB | 0/0 | 100.0 | 98.9 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00007 | 122657 | 125734 | MDTC | 0/0 | 100.0 | 99.8 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00038 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 99.7 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00038 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 99.9 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00001 | 138913 | 140139 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00001 | 148768 | 149976 | MDTH | 0/0 | 100.0 | 98.3 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00011 | 115559 | 115888 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00011 | 115207 | 115572 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00011 | 43747 | 45120 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00072 | 465 | 1676 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00019 | 71052 | 72083 | MDTN | 0/0 | 100.0 | 99.5 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00019 | 69001 | 71052 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00019 | 67538 | 69004 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00002 | 114229 | 114705 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00001 | 2196 | 3944 | MSBA | 0/0 | 100.0 | 99.9 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00023 | 60539 | 62440 | PBP2 | 0/0 | 100.0 | 99.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00002 | 169833 | 171137 | PBP4B | 0/0 | 100.0 | 98.7 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00006 | 110978 | 111946 | PMRF | 0/0 | 100.0 | 99.9 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00075 | 2160 | 2816 | QNRS | 0/0 | 100.0 | 100.0 | MEG_6020 | Drugs:Fluoroquinolones:Quinolone_resistance_protein_Qnr:QNRS | NA |
| contig00026 | 21725 | 22594 | ROBA | 0/0 | 100.0 | 98.8 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00019 | 45260 | 45582 | SOXS | 0/0 | 99.7 | 99.7 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00088 | 3459 | 4274 | SULII | 0/0 | 100.0 | 100.0 | MEG_6617 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULII | NA |
| contig00075 | 9296 | 10087 | SULIII | 0/0 | 100.0 | 100.0 | MEG_6639 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULIII | NA |
| contig00075 | 7811 | 9056 | TEM | 0/0 | 98.3 | 99.4 | MEG_6875 | Drugs:betalactams:Class_A_betalactamases:TEM | NA |
| contig00051 | 22605 | 24248 | YOGI | 0/0 | 100.0 | 99.9 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00061 | 2721 | 3522 | aadA2_1 | 0/0 | 97.9 | 99.9 | NC_010870 | aadA2 | Streptomycin |
| contig00085 | 1684 | 2559 | blaCTX-M-15_1 | 0/0 | 100.0 | 100.0 | AY044436 | blaCTX-M-15 | Amoxicillin, Ampicillin, Aztreonam, Cefepime, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Ticarcillin |
| contig00061 | 1826 | 2323 | dfrA12_8 | 0/0 | 100.0 | 100.0 | AM040708 | dfrA12 | Trimethoprim |
| contig00088 | 266 | 1029 | erm(B)_18 | 2/2 | 100.0 | 99.0 | X66468 | erm(B) | Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin_IA, Virginiamycin_S |
| contig00002 | 84130 | 85362 | mdf(A)_1 | 0/0 | 100.0 | 99.9 | Y08743 | mdf(A) | |
| contig00061 | 10161 | 11091 | mph(A)_2 | 2/10 | 100.0 | 98.7 | U36578 | mph(A) | Erythromycin, Azithromycin, Spiramycin, Telithromycin |
| contig00061 | 4000 | 4866 | sul1_5 | 0/0 | 100.0 | 99.9 | EU780013 | sul1 | Sulfamethoxazole |
| contig00083 | 850 | 2055 | tet(B)_2 | 0/0 | 100.0 | 100.0 | AF326777 | tet(B) | Doxycycline, Tetracycline, Minocycline |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00061 | 2743 | 3522 | aadA2 | 0/0 | 100.0 | 99.9 | AF156486:5012-5792 | aadA2 is an aminoglycoside nucleotidyltransferase gene encoded by plasmids and integrons in K. pneumoniae Salmonella spp. Corynebacterium glutamicum C. freundii and Aeromonas spp. | aminoglycoside |
| contig00001 | 99712 | 102861 | acrB | 0/0 | 100.0 | 100.0 | U00096.3:484403-481253 | Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00009 | 135351 | 138464 | acrD | 0/0 | 100.0 | 100.0 | AP009048.1:2586250-2589364 | AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole and is regulated by baeRS and cpxAR. | aminoglycoside |
| contig00011 | 127888 | 129045 | acrE | 0/0 | 100.0 | 99.9 | U00096:3413863-3415021 | AcrE is a membrane fusion protein similar to AcrA. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00011 | 129057 | 132161 | acrF | 0/0 | 100.0 | 99.9 | U00096:3415032-3418137 | AcrF is a inner membrane transporter similar to AcrB. | cephalosporin, cephamycin, fluoroquinolone, penam |
| contig00011 | 126827 | 127489 | acrS | 0/0 | 100.0 | 100.0 | U00096:3413465-3412802 | AcrS is a repressor of the AcrAB efflux complex and is associated with the expression of AcrEF. AcrS is believed to regulate a switch between AcrAB and AcrEF efflux. | cephalosporin, cephamycin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00008 | 90602 | 91423 | bacA | 0/0 | 100.0 | 99.9 | U00096.3:3204131-3203309 | The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin. | peptide |
| contig00041 | 29821 | 30543 | baeR | 0/0 | 100.0 | 99.6 | AP009048.1:2166412-2167135 | BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes. | aminocoumarin, aminoglycoside |
| contig00041 | 28421 | 29824 | baeS | 0/0 | 100.0 | 100.0 | AP009048:2165012-2166416 | BaeS is a sensor kinase in the BaeSR regulatory system. While it phosphorylates BaeR to increase its activity BaeS is not necessary for overexpressed BaeR to confer resistance. | aminocoumarin, aminoglycoside |
| contig00013 | 61323 | 62696 | cpxA | 0/0 | 100.0 | 99.0 | BA000007.3:4905062-4903688 | CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR which promotes efflux complex expression. | aminocoumarin, aminoglycoside |
| contig00010 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | AP009048.1:4154296-4153663 | CRP is a global regulator that represses MdtEF multidrug efflux pump expression. | fluoroquinolone, macrolide, penam |
| contig00085 | 1684 | 2559 | CTX-M-15 | 0/0 | 100.0 | 100.0 | AY044436:1435-2311 | CTX-M-15 is a beta-lactamase found in the Enterobacteriaceae family | cephalosporin |
| contig00061 | 1826 | 2323 | dfrA12 | 0/0 | 100.0 | 100.0 | GU585907.1:22103-21605 | dfrA12 is an integron-encoded dihydrofolate reductase found in Vibrio cholerae | diaminopyrimidine |
| contig00007 | 90366 | 91538 | emrA | 0/0 | 100.0 | 100.0 | AP009048:2810082-2811255 | EmrA is a membrane fusion protein providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli a Gram-negative bacterium. | fluoroquinolone |
| contig00007 | 91555 | 93093 | emrB | 0/0 | 100.0 | 100.0 | U00096:2812615-2814154 | emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP) nalidixic acid and thioloactomycin. | fluoroquinolone |
| contig00023 | 1067 | 2122 | emrK | 0/0 | 100.0 | 99.7 | D78168:536-1592 | emrK is a membrane fusion protein that is a homolog of EmrA. Together with the inner membrane transporter EmrY and the outer membrane channel TolC it mediates multidrug efflux. | tetracycline |
| contig00007 | 89709 | 90239 | emrR | 0/0 | 100.0 | 99.8 | U00096.3:2810769-2811300 | EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression. | fluoroquinolone |
| contig00030 | 7740 | 9383 | eptA | 0/0 | 100.0 | 99.9 | AP009048:4340268-4338624 | PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine resulting in a less negative cell membrane and decreased binding of polymyxin B. | peptide |
| contig00088 | 292 | 1037 | ErmB | 1/1 | 99.9 | 99.2 | AF242872.1:2131-2878 | ErmB confers the MLSb phenotype. Similar to ErmC expression of ErmB is inducible by erythromycin. The leader peptide causes attenuation of the mRNA and stabilizes the structure preventing further translation. When erythromycin is present it binds the leader peptide causing a change in conformation allowing for the expression of ErmB. | lincosamide, macrolide, streptogramin |
| contig00001 | 98496 | 99689 | Escherichia_coli_acrA | 0/0 | 100.0 | 100.0 | U00096.3:485619-484425 | AcrA is a subunit of the AcrAB-TolC multidrug efflux system that in E. coli. | cephalosporin, fluoroquinolone, glycylcycline, penam, phenicol, rifamycin, tetracycline, triclosan |
| contig00006 | 107745 | 108878 | Escherichia_coli_ampC | 0/0 | 100.0 | 100.0 | U00096.3:4378944-4377810 | A class C ampC beta-lactamase (cephalosporinase) enzyme described in Escherichia coli shown clinically to confer resistance to penicillin-like and cephalosporin-class antibiotics. | cephalosporin, penam |
| contig00023 | 65523 | 66827 | Escherichia_coli_ampC1_beta-lactamase | 0/0 | 100.0 | 100.0 | FN649414.1:2765050-2766355 | An ampC-like beta-lactamase identified from Escherichia coli. | cephalosporin, penam |
| contig00001 | 187826 | 188983 | Escherichia_coli_ampH | 0/0 | 100.0 | 100.0 | AP012030.1:396711-395553 | AmpH is a class C ampC-like beta-lactamase and penicillin-binding protein identified in Escherichia coli. | cephalosporin, penam |
| contig00002 | 84130 | 85362 | Escherichia_coli_mdfA | 0/0 | 100.0 | 98.4 | JQ394987:0-1233 | Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter. | benzalkonium_chloride, rhodamine, tetracycline |
| contig00023 | 2646 | 3260 | evgA | 0/0 | 100.0 | 99.0 | BA000007.3:3212025-3212640 | EvgA when phosphorylated is a positive regulator for efflux protein complexes emrKY and mdtEF. While usually phosphorylated in a EvgS dependent manner it can be phosphorylated in the absence of EvgS when overexpressed. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00023 | 3265 | 6858 | evgS | 0/0 | 100.0 | 99.4 | U00096:2484373-2487967 | EvgS is a sensor protein that phosphorylates the regulatory protein EvgA. evgS corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | fluoroquinolone, macrolide, penam, tetracycline |
| contig00036 | 1784 | 2512 | gadW | 0/0 | 100.0 | 94.7 | CP015085.1:2552440-2551711 | GadW is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. GadW inhibits GadX-dependent activation. GadW clearly represses gadX and in situations where GadX is missing activates gadA and gadBC. | fluoroquinolone, macrolide, penam |
| contig00036 | 592 | 1416 | gadX | 0/0 | 100.0 | 100.0 | AP009048.1:3974604-3975429 | GadX is an AraC-family regulator that promotes mdtEF expression to confer multidrug resistance. | fluoroquinolone, macrolide, penam |
| contig00004 | 91674 | 92087 | H-NS | 0/0 | 100.0 | 99.3 | BA000007.3:1738104-1737690 | H-NS is a histone-like protein involved in global gene regulation in Gram-negative bacteria. It is a repressor of the membrane fusion protein genes acrE mdtE and emrK as well as nearby genes of many RND-type multidrug exporters. | cephalosporin, cephamycin, fluoroquinolone, macrolide, penam, tetracycline |
| contig00024 | 8166 | 8843 | kdpE | 0/0 | 100.0 | 100.0 | U00096.3:721733-721055 | kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. | aminoglycoside |
| contig00042 | 31344 | 31727 | marA | 0/0 | 100.0 | 100.0 | AP009048.1:1621287-1621671 | In the presence of antibiotic stress E. coli overexpresses the global activator protein MarA which besides inducing MDR efflux pump AcrAB also down- regulates synthesis of the porin OmpF. | carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, monobactam, penam, penem, phenicol, rifamycin, tetracycline, triclosan |
| contig00041 | 19561 | 20808 | mdtA | 0/0 | 100.0 | 97.9 | U00096:2154015-2155263 | MdtA is the membrane fusion protein of the multidrug efflux complex mdtABC. | aminocoumarin |
| contig00041 | 20808 | 23930 | mdtB | 0/0 | 100.0 | 99.2 | U00096:2155262-2158385 | MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. | aminocoumarin |
| contig00041 | 23931 | 27008 | mdtC | 0/0 | 100.0 | 99.0 | U00096:2158385-2161463 | MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58. | aminocoumarin |
| contig00036 | 6013 | 7170 | mdtE | 0/0 | 100.0 | 100.0 | AP009048.1:3981183-3980025 | MdtE is the membrane fusion protein of the MdtEF multidrug efflux complex. It shares 70% sequence similarity with AcrA. | fluoroquinolone, macrolide, penam |
| contig00036 | 2875 | 5988 | mdtF | 0/0 | 100.0 | 100.0 | U00096:3660413-3663527 | MdtF is the multidrug inner membrane transporter for the MdtEF-TolC efflux complex. | fluoroquinolone, macrolide, penam |
| contig00032 | 18401 | 19627 | mdtG | 0/0 | 100.0 | 99.4 | CP000800.1:1192954-1191727 | The MdtG protein also named YceE appears to be a member of the major facilitator superfamily of transporters and it has been reported when overexpressed to increase fosfomycin and deoxycholate resistances. mdtG is a member of the marA-soxS-rob regulon. | fosfomycin |
| contig00032 | 28256 | 29464 | mdtH | 0/0 | 100.0 | 100.0 | U00096:1125326-1124117 | Multidrug resistance protein MdtH | fluoroquinolone |
| contig00048 | 473 | 1684 | mdtM | 0/0 | 98.3 | 95.5 | U00096.3:4568519-4567286 | Multidrug resistance protein MdtM | acridine_dye, fluoroquinolone, lincosamide, nucleoside, phenicol |
| contig00015 | 21771 | 22802 | mdtN | 0/0 | 100.0 | 100.0 | AP009048.1:4307588-4306556 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride. | acridine_dye, nucleoside |
| contig00015 | 22802 | 24853 | mdtO | 0/0 | 100.0 | 100.0 | AP009048.1:4306557-4304505 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00015 | 24850 | 26316 | mdtP | 0/0 | 100.0 | 100.0 | AP009048.1:4304509-4303042 | Multidrug resistance efflux pump. Could be involved in resistance to puromycin acriflavine and tetraphenylarsonium chloride | acridine_dye, nucleoside |
| contig00061 | 10189 | 11091 | mphA | 0/0 | 99.7 | 100.0 | D16251.1:2531-1625 | The mphA gene encodes for resistance enzyme MPH(2’)-I which preferentially inactivate 14-membered macrolides (e.g.erythromycin telithromycin roxithromycin) over 16-membered macrolides (e.g.tylosin spiramycin). It phosphorylates macrolides at 2’-OH hydroxyl of desosamine sugar of macrolides in a GTP-dependent manner. | macrolide |
| contig00009 | 114189 | 114665 | mphB | 0/0 | 100.0 | 98.3 | AE005174.2:3397370-3397847 | The mphB gene encodes for MPH(2’)-II. This enzymes phosphorylates 14-membered and 16-membered macrolides. It phosphorylates macrolides in GTP- dependent manner at 2’-OH hydroxyl of desosamine sugar of macrolides. | macrolide |
| contig00002 | 167077 | 168825 | msbA | 0/0 | 100.0 | 100.0 | U00096.3:966620-968369 | MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A a major component of the bacterial outer cell membrane and is the only bacterial ABC transporter that is essential for cell viability. | nitroimidazole |
| contig00003 | 173789 | 174757 | pmrF | 0/0 | 100.0 | 100.0 | U00096:2367070-2368039 | PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58. | peptide |
| contig00061 | 4027 | 4866 | sul1 | 0/0 | 100.0 | 100.0 | JF969163:1053-1893 | Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons. | sulfonamide |
| contig00083 | 850 | 2055 | tet(B) | 0/0 | 100.0 | 99.8 | AB089595:0-1206 | Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline doxycycline and minocycline but not tigecycline. | tetracycline |
| contig00008 | 66737 | 68224 | tolC | 0/0 | 100.0 | 100.0 | FJ768952:0-1488 | TolC is a protein subunit of many multidrug efflux complexes in Gram negative bacteria. It is an outer membrane efflux protein and is constitutively open. Regulation of efflux activity is often at its periplasmic entrance by other components of the efflux complex. | aminocoumarin, aminoglycoside, carbapenem, cephalosporin, cephamycin, fluoroquinolone, glycylcycline, macrolide, penam, penem, peptide, phenicol, rifamycin, tetracycline, triclosan |
| contig00003 | 113686 | 115329 | yojI | 0/0 | 100.0 | 100.0 | U00096.3:2308615-2306971 | YojI mediates resistance to the peptide antibiotic microcin J25 when it is expressed from a multicopy vector. YojI is capable of pumping out microcin molecules. The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI. | peptide |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00061 | 2743 | 3522 | (AGly)aadA2 | 0/0 | 100.0 | 99.9 | X68227:66-945 | (AGly)aadA2 | NA |
| contig00023 | 65523 | 66827 | (Bla)AmpC1_Ecoli | 0/0 | 100.0 | 100.0 | FN649414:2765051-2766355 | (Bla)AmpC1_Ecoli | NA |
| contig00006 | 107745 | 108878 | (Bla)AmpC2_Ecoli | 0/0 | 100.0 | 100.0 | CP002970:332756-333889 | (Bla)AmpC2_Ecoli | NA |
| contig00001 | 187826 | 188983 | (Bla)ampH_Ecoli | 0/0 | 100.0 | 100.0 | AP012030:395554-396711 | (Bla)ampH_Ecoli | NA |
| contig00085 | 1684 | 2559 | (Bla)blaCTX-M-15 | 0/0 | 100.0 | 100.0 | JQ686199:261-1136 | (Bla)blaCTX-M-15 | NA |
| contig00024 | 60253 | 62154 | (Bla)Penicillin_Binding_Protein_Ecoli | 0/0 | 100.0 | 100.0 | CP002291:664439-666340 | (Bla)Penicillin_Binding_Protein_Ecoli | NA |
| contig00088 | 292 | 1029 | (MLS)erm(B) | 0/0 | 100.0 | 99.6 | M11180:714-1451 | (MLS)erm(B) | NA |
| contig00061 | 10189 | 11091 | (MLS)mph(A) | 0/0 | 99.7 | 100.0 | DQ445270:1626-2531 | (MLS)mph(A) | NA |
| contig00061 | 4027 | 4866 | (Sul)sul1 | 0/0 | 100.0 | 100.0 | AF071413:6700-7539 | (Sul)sul1 | NA |
| contig00083 | 850 | 2055 | (Tet)tetB | 0/0 | 100.0 | 99.7 | AB089594:1-1206 | (Tet)tetB | NA |
| contig00061 | 1826 | 2323 | (Tmt)dfrA12 | 0/0 | 100.0 | 100.0 | Z21672:310-807 | (Tmt)dfrA12 | NA |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00061 | 2731 | 3522 | aadA2 | 0/0 | 100 | 100.0 | NG_047343.1 | ANT(3’’)-Ia family aminoglycoside nucleotidyltransferase AadA2 | STREPTOMYCIN |
| contig00085 | 1684 | 2559 | blaCTX-M-15 | 0/0 | 100 | 100.0 | NG_048935.1 | class A extended-spectrum beta-lactamase CTX-M-15 | CEPHALOSPORIN |
| contig00006 | 107745 | 108878 | blaEC | 0/0 | 100 | 100.0 | NG_047494.1 | BlaEC family class C beta-lactamase | BETA-LACTAM |
| contig00061 | 1826 | 2323 | dfrA12 | 0/0 | 100 | 100.0 | NG_047689.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | TRIMETHOPRIM |
| contig00088 | 292 | 1029 | erm(B) | 0/0 | 100 | 99.9 | NG_047804.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | MACROLIDE |
| contig00061 | 10161 | 11091 | mph(A) | 2/10 | 100 | 98.7 | NG_047986.1 | Mph(A) family macrolide 2’-phosphotransferase | MACROLIDE |
| contig00061 | 4027 | 4866 | sul1 | 0/0 | 100 | 100.0 | NG_048082.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | SULFONAMIDE |
| contig00083 | 850 | 2055 | tet(B) | 0/0 | 100 | 100.0 | NG_048163.1 | tetracycline efflux MFS transporter Tet(B) | TETRACYCLINE |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product | Resistance |
|---|---|---|---|---|---|---|---|---|---|
| contig00001 | 98496 | 99689 | ACRA | 0/0 | 100.0 | 100.0 | MEG_399 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRA | NA |
| contig00001 | 99712 | 102861 | ACRB | 0/0 | 100.0 | 100.0 | MEG_401 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRB | NA |
| contig00009 | 135351 | 138464 | ACRD | 0/0 | 100.0 | 100.0 | MEG_407 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ACRD | NA |
| contig00011 | 127888 | 129045 | ACRE | 0/0 | 100.0 | 99.9 | MEG_408 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRE | NA |
| contig00011 | 129057 | 132161 | ACRF | 0/0 | 100.0 | 99.9 | MEG_409 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:ACRF | NA |
| contig00011 | 126827 | 127489 | ACRS | 0/0 | 100.0 | 100.0 | MEG_415 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:ACRS | NA |
| contig00006 | 107745 | 108878 | AMPC | 0/0 | 100.0 | 100.0 | MEG_728 | Drugs:betalactams:Class_C_betalactamases:AMPC | NA |
| contig00001 | 187826 | 188983 | AMPH | 0/0 | 100.0 | 100.0 | MEG_729 | Drugs:betalactams:Penicillin_binding_protein:AMPH | NA |
| contig00061 | 2721 | 3522 | ANT3-DPRIME | 0/0 | 97.9 | 99.9 | MEG_975 | Drugs:Aminoglycosides:Aminoglycoside_O-nucleotidyltransferases:ANT3-DPRIME | NA |
| contig00041 | 5770 | 7622 | ASMA | 0/0 | 100.0 | 97.5 | MEG_1180 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_regulator:ASMA | NA |
| contig00008 | 90602 | 91423 | BACA | 0/0 | 100.0 | 99.9 | MEG_1190 | Drugs:Bacitracin:Undecaprenyl_pyrophosphate_phosphatase:BACA | NA |
| contig00041 | 29821 | 30543 | BAER | 0/0 | 100.0 | 99.6 | MEG_1192 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAER | NA |
| contig00041 | 28421 | 29824 | BAES | 0/0 | 100.0 | 100.0 | MEG_1193 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_regulator:BAES | NA |
| contig00003 | 86709 | 87899 | BCR | 0/0 | 100.0 | 99.9 | MEG_1210 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:BCR | NA |
| contig00013 | 60628 | 61326 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2122 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00013 | 61323 | 62696 | CPXAR | 0/0 | 100.0 | 100.0 | MEG_2121 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CPXAR | NA |
| contig00010 | 15201 | 15833 | CRP | 0/0 | 100.0 | 99.7 | MEG_2132 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:CRP | NA |
| contig00106 | 61 | 984 | CTX | 0/0 | 98.0 | 98.3 | MEG_2435 | Drugs:betalactams:Class_A_betalactamases:CTX | NA |
| contig00061 | 1826 | 2323 | DFRA | 0/0 | 100.0 | 100.0 | MEG_2551 | Drugs:Trimethoprim:Dihydrofolate_reductase:DFRA | NA |
| contig00007 | 90366 | 91538 | EMRA | 0/0 | 100.0 | 100.0 | MEG_2722 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRA | NA |
| contig00007 | 91555 | 93093 | EMRB | 0/0 | 100.0 | 100.0 | MEG_2725 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRB | NA |
| contig00012 | 87171 | 88361 | EMRD | 0/0 | 100.0 | 100.0 | MEG_2729 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRD | NA |
| contig00023 | 1067 | 2230 | EMRK | 0/0 | 100.0 | 99.7 | MEG_2732 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:EMRK | NA |
| contig00007 | 89709 | 90239 | EMRR | 0/0 | 100.0 | 99.8 | MEG_2734 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EMRR | NA |
| contig00030 | 7740 | 9383 | EPTA | 0/0 | 100.0 | 99.9 | MEG_2739 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:EPTA | NA |
| contig00088 | 266 | 1029 | ERMB | 2/2 | 100.0 | 99.0 | MEG_2801 | Drugs:MLS:23S_rRNA_methyltransferases:ERMB | NA |
| contig00023 | 3265 | 6858 | EVGS | 0/0 | 100.0 | 99.4 | MEG_2870 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_regulator:EVGS | NA |
| contig00036 | 1784 | 2512 | GADW | 0/0 | 100.0 | 100.0 | MEG_3081 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADW | NA |
| contig00036 | 592 | 1416 | GADX | 0/0 | 100.0 | 100.0 | MEG_3083 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:GADX | NA |
| contig00004 | 91674 | 92087 | HNS | 0/0 | 100.0 | 99.3 | MEG_3271 | Drugs:Multi-drug_resistance:Multi-drug_RND_efflux_pumps:HNS | NA |
| contig00024 | 8166 | 8843 | KDPE | 0/0 | 100.0 | 100.0 | MEG_3448 | Drugs:Aminoglycosides:Aminoglycoside_efflux_pumps:KDPE | NA |
| contig00042 | 31338 | 31727 | MARA | 0/0 | 100.0 | 100.0 | MEG_3662 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARA | NA |
| contig00042 | 30890 | 31324 | MARR | 0/0 | 100.0 | 100.0 | MEG_3663 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_regulator:MARR | NA |
| contig00002 | 84130 | 85362 | MDFA | 0/0 | 100.0 | 100.0 | MEG_3737 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDFA | NA |
| contig00041 | 19561 | 20808 | MDTA | 0/0 | 100.0 | 97.9 | MEG_3746 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTA | NA |
| contig00041 | 20808 | 23930 | MDTB | 0/0 | 100.0 | 99.2 | MEG_3747 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTB | NA |
| contig00041 | 23931 | 27008 | MDTC | 0/0 | 100.0 | 99.0 | MEG_3749 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:MDTC | NA |
| contig00036 | 6013 | 7170 | MDTE | 0/0 | 100.0 | 100.0 | MEG_3751 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTE | NA |
| contig00036 | 2875 | 5988 | MDTF | 0/0 | 100.0 | 100.0 | MEG_3752 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTF | NA |
| contig00032 | 18401 | 19627 | MDTG | 0/0 | 100.0 | 100.0 | MEG_3753 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTG | NA |
| contig00032 | 28256 | 29464 | MDTH | 0/0 | 100.0 | 100.0 | MEG_3755 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTH | NA |
| contig00039 | 1757 | 2086 | MDTI | 0/0 | 100.0 | 100.0 | MEG_3756 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTI | NA |
| contig00039 | 2073 | 2438 | MDTJ | 0/0 | 100.0 | 99.5 | MEG_3757 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_SMR_efflux_pumps:MDTJ | NA |
| contig00026 | 31959 | 33332 | MDTK | 0/0 | 100.0 | 98.8 | MEG_3759 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MATE_efflux_pumps:MDTK | NA |
| contig00048 | 473 | 1684 | MDTM | 0/0 | 98.3 | 95.5 | MEG_3761 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_MFS_efflux_pumps:MDTM | NA |
| contig00015 | 21771 | 22802 | MDTN | 0/0 | 100.0 | 100.0 | MEG_3763 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTN | NA |
| contig00015 | 22802 | 24853 | MDTO | 0/0 | 100.0 | 100.0 | MEG_3764 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTO | NA |
| contig00015 | 24850 | 26316 | MDTP | 0/0 | 100.0 | 100.0 | MEG_3765 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_RND_efflux_pumps:MDTP | NA |
| contig00061 | 10161 | 11091 | MPHA | 2/10 | 100.0 | 98.7 | MEG_4030 | Drugs:MLS:Macrolide_phosphotransferases:MPHA | NA |
| contig00009 | 114189 | 114665 | MPHB | 0/0 | 100.0 | 98.3 | MEG_4033 | Drugs:MLS:Macrolide_phosphotransferases:MPHB | NA |
| contig00002 | 167077 | 168825 | MSBA | 0/0 | 100.0 | 100.0 | MEG_4061 | Drugs:Multi-drug_resistance:Multi-drug_ABC_efflux_pumps:MSBA | NA |
| contig00024 | 60253 | 62154 | PBP2 | 0/0 | 100.0 | 100.0 | MEG_5400 | Drugs:betalactams:Penicillin_binding_protein:PBP2 | NA |
| contig00023 | 65523 | 66827 | PBP4B | 0/0 | 100.0 | 100.0 | MEG_5409 | Drugs:betalactams:Penicillin_binding_protein:PBP4B | NA |
| contig00003 | 173789 | 174757 | PMRF | 0/0 | 100.0 | 100.0 | MEG_5801 | Drugs:Cationic_antimicrobial_peptides:Lipid_A_modification:PMRF | NA |
| contig00005 | 38665 | 39534 | ROBA | 0/0 | 100.0 | 99.0 | MEG_6082 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_RND_efflux_pumps:ROBA | NA |
| contig00015 | 47933 | 48256 | SOXS | 0/0 | 100.0 | 100.0 | MEG_6551 | Multi-compound:Drug_and_biocide_and_metal_resistance:Drug_and_biocide_and_metal_resistance_regulator:SOXS | NA |
| contig00061 | 4026 | 4993 | SULI | 0/0 | 100.0 | 100.0 | MEG_6615 | Drugs:Sulfonamides:Sulfonamide-resistant_dihydropteroate_synthases:SULI | NA |
| contig00083 | 850 | 2055 | TETB | 0/0 | 100.0 | 100.0 | MEG_7052 | Drugs:Tetracyclines:Tetracycline_resistance_MFS_efflux_pumps:TETB | NA |
| contig00003 | 113686 | 115329 | YOGI | 0/0 | 100.0 | 100.0 | MEG_7842 | Multi-compound:Drug_and_biocide_resistance:Drug_and_biocide_ABC_efflux_pumps:YOGI | NA |
Presence/Absence of antibiotic resistance genes (coverage and identity > 90%) on each sample
| Field | Description |
|---|---|
| Contig | Contig name where the gene was found |
| Start | Start position of the gene within the contig |
| End | End position of the gene within the contig |
| Gene | Antibiotic resistance gene |
| Gaps | Gaps in subject (genome) and query (antibiotic resistance gene) |
| Coverage | Proportion (%) of the gene covered |
| Identity | Proportion (%) of exact nucleotide matches |
| Accession | Accesion number of the antibiotic resistance gene |
| Product | Antibiotic resistance gene product |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00052 | 400 | 632 | Col(BS512)_1 | 0/0 | 100.0 | 100.0 | NC_010656 | Col(BS512)_1__NC_010656 |
| contig00037 | 3630 | 3771 | Col156_1 | 0/0 | 92.2 | 98.6 | NC_009781 | Col156_1__NC_009781 |
| contig00044 | 3338 | 3491 | Col156_1 | 0/0 | 100.0 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00031 | 14320 | 14707 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00033 | 14397 | 15078 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 96.6 | AP001918 | IncFIB(AP001918)_1__AP001918 |
## [1] "NO PLASMID FOUND!!"
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00073 | 13248 | 13807 | IncFIB(K)_1_Kpn3 | 0/0 | 100 | 98.8 | JN233704 | IncFIB(K)_1_Kpn3_JN233704 |
| contig00039 | 16038 | 16776 | IncL/M(pMU407)_1_pMU407 | 0/0 | 100 | 99.5 | U27345 | IncL/M(pMU407)_1_pMU407_U27345 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00230 | 459 | 613 | IncB/O/K/Z_2 | 1/1 | 96.2 | 95.5 | GU256641 | IncB/O/K/Z_2__GU256641 |
| contig00288 | 462 | 613 | IncB/O/K/Z_3 | 0/0 | 100.0 | 99.3 | GQ259888 | IncB/O/K/Z_3__GQ259888 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00025 | 12158 | 12545 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00309 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00413 | 3304 | 3553 | IncFII_1 | 0/0 | 95.8 | 100.0 | AY458016 | IncFII_1__AY458016 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00065 | 1438 | 1579 | Col156_1 | 0/0 | 92.2 | 98.6 | NC_009781 | Col156_1__NC_009781 |
| contig00253 | 4077 | 4230 | Col156_1 | 0/0 | 100.0 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00381 | 414 | 620 | Col8282_1 | 0/0 | 100.0 | 100.0 | DQ995352 | Col8282_1__DQ995352 |
| contig01853 | 681 | 1068 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00043 | 8903 | 9584 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 96.9 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00003 | 7323 | 7696 | IncX1_1 | 0/0 | 100.0 | 98.4 | EU370913 | IncX1_1__EU370913 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00101 | 433 | 694 | Col(MG828)_1 | 0/0 | 100 | 92.8 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00045 | 3365 | 3752 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00045 | 26541 | 27222 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00062 | 3328 | 3588 | IncFII(pAMA1167-NDM-5)_1_pAMA1167-NDM-5 | 0/0 | 100 | 98.1 | CP024805.1 | IncFII(pAMA1167-NDM-5)_1_pAMA1167-NDM-5_CP024805.1 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00115 | 433 | 694 | Col(MG828)_1 | 0/0 | 100 | 92.8 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00073 | 9286 | 9673 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00074 | 8768 | 9449 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00070 | 3328 | 3588 | IncFII(pAMA1167-NDM-5)_1_pAMA1167-NDM-5 | 0/0 | 100 | 98.1 | CP024805.1 | IncFII(pAMA1167-NDM-5)_1_pAMA1167-NDM-5_CP024805.1 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00070 | 14298 | 14685 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00097 | 1569 | 2250 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00094 | 3324 | 3584 | IncFII_1 | 0/0 | 100 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00061 | 13995 | 14136 | IncI1_1_Alpha | 0/0 | 100 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00211 | 4 | 114 | Col440I_1 | 0/0 | 97.4 | 92.8 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00092 | 14297 | 14684 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00144 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00091 | 3323 | 3583 | IncFII_1 | 0/0 | 100.0 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00096 | 1715 | 1856 | IncI1_1_Alpha | 0/0 | 100.0 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00067 | 3630 | 3771 | Col156_1 | 0/0 | 92.2 | 98.6 | NC_009781 | Col156_1__NC_009781 |
| contig00077 | 3338 | 3491 | Col156_1 | 0/0 | 100.0 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00062 | 10944 | 11331 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00059 | 14397 | 15078 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 96.6 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00105 | 366 | 476 | Col440I_1 | 0/0 | 97.4 | 93.7 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00031 | 4855 | 5115 | IncFII(pCoo)_1_pCoo | 1/1 | 99.6 | 96.6 | CR942285 | IncFII(pCoo)_1_pCoo_CR942285 |
| contig00054 | 24232 | 24605 | IncX2_1 | 0/0 | 100.0 | 100.0 | JQ269335 | IncX2_1__JQ269335 |
| contig00078 | 1713 | 2477 | IncY_1 | 0/0 | 100.0 | 99.5 | K02380 | IncY_1__K02380 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00131 | 428 | 686 | Col(MG828)_1 | 1/1 | 98.8 | 95.0 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00106 | 4075 | 4228 | Col156_1 | 0/0 | 100.0 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00110 | 414 | 620 | Col8282_1 | 0/0 | 100.0 | 100.0 | DQ995352 | Col8282_1__DQ995352 |
| contig00111 | 1730 | 1860 | ColRNAI_1 | 1/1 | 100.0 | 90.1 | DQ298019 | ColRNAI_1__DQ298019 |
| contig00064 | 6481 | 6640 | IncB/O/K/Z_2 | 0/0 | 100.0 | 100.0 | GU256641 | IncB/O/K/Z_2__GU256641 |
| contig00102 | 1412 | 1672 | IncFII_1 | 0/0 | 100.0 | 100.0 | AY458016 | IncFII_1__AY458016 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00807 | 789 | 1176 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00322 | 1 | 616 | IncFIB(AP001918)_1 | 0/0 | 90.3 | 98.5 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00530 | 768 | 909 | IncI1_1_Alpha | 0/0 | 100.0 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00072 | 14298 | 14685 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00095 | 1417 | 2098 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00044 | 38031 | 38291 | IncFII_1 | 0/0 | 100 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00057 | 15823 | 15964 | IncI1_1_Alpha | 0/0 | 100 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00058 | 14298 | 14685 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00081 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00038 | 38031 | 38291 | IncFII_1 | 0/0 | 100 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00048 | 16406 | 16547 | IncI1_1_Alpha | 0/0 | 100 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00090 | 1088 | 1198 | Col440I_1 | 0/0 | 97.4 | 92.8 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00056 | 14298 | 14685 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00075 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00039 | 38451 | 38711 | IncFII_1 | 0/0 | 100.0 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00054 | 12304 | 12445 | IncI1_1_Alpha | 0/0 | 100.0 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00062 | 14298 | 14685 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00081 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00040 | 38031 | 38291 | IncFII_1 | 0/0 | 100 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00052 | 15823 | 15964 | IncI1_1_Alpha | 0/0 | 100 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00072 | 433 | 694 | Col(MG828)_1 | 0/0 | 100.0 | 93.1 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00037 | 5825 | 5979 | IncB/O/K/Z_2 | 1/1 | 96.2 | 96.1 | GU256641 | IncB/O/K/Z_2__GU256641 |
| contig00049 | 1436 | 2117 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00031 | 7275 | 7648 | IncX1_1 | 0/0 | 100.0 | 98.4 | EU370913 | IncX1_1__EU370913 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00079 | 433 | 694 | Col(MG828)_1 | 0/0 | 100 | 93.5 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00063 | 4077 | 4230 | Col156_1 | 0/0 | 100 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00042 | 16297 | 16684 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00042 | 5009 | 5690 | IncFIB(AP001918)_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00068 | 1039 | 1923 | p0111_1 | 0/0 | 100 | 98.6 | AP010962 | p0111_1__AP010962 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00055 | 14298 | 14685 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00078 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00035 | 41580 | 41840 | IncFII_1 | 0/0 | 100 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00046 | 15823 | 15964 | IncI1_1_Alpha | 0/0 | 100 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00100 | 1088 | 1198 | Col440I_1 | 0/0 | 97.4 | 92.8 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00061 | 14298 | 14685 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00083 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00040 | 38031 | 38291 | IncFII_1 | 0/0 | 100.0 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00071 | 57 | 198 | IncI1_1_Alpha | 0/0 | 100.0 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00112 | 519 | 632 | Col440I_1 | 0/0 | 100 | 90.3 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00113 | 155 | 268 | Col440I_1 | 0/0 | 100 | 91.2 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00105 | 255 | 768 | IncN_1 | 0/0 | 100 | 99.8 | AY046276 | IncN_1__AY046276 |
## [1] "NO PLASMID FOUND!!"
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00024 | 56680 | 56832 | IncB/O/K/Z_2 | 1/1 | 95 | 96.1 | GU256641 | IncB/O/K/Z_2__GU256641 |
| contig00049 | 5210 | 5891 | IncFIB(AP001918)_1 | 0/0 | 100 | 97.8 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00069 | 278 | 791 | IncN_1 | 0/0 | 100 | 100.0 | AY046276 | IncN_1__AY046276 |
| contig00062 | 9173 | 9546 | IncX2_1 | 0/0 | 100 | 99.7 | JQ269335 | IncX2_1__JQ269335 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00114 | 400 | 632 | Col(BS512)_1 | 0/0 | 100.0 | 100.0 | NC_010656 | Col(BS512)_1__NC_010656 |
| contig00120 | 429 | 690 | Col(MG828)_1 | 0/0 | 100.0 | 91.6 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00072 | 3584 | 3725 | Col156_1 | 0/0 | 92.2 | 98.6 | NC_009781 | Col156_1__NC_009781 |
| contig00046 | 19761 | 20148 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00046 | 8473 | 9154 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00033 | 41587 | 41847 | IncFII(pRSB107)_1_pRSB107 | 0/0 | 100.0 | 100.0 | AJ851089 | IncFII(pRSB107)_1_pRSB107_AJ851089 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00082 | 4078 | 4231 | Col156_1 | 0/0 | 100 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00057 | 9159 | 9542 | IncFIA_1 | 0/0 | 99 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00064 | 8464 | 9145 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00041 | 6604 | 6757 | Col156_1 | 0/0 | 100 | 98.7 | NC_009781 | Col156_1__NC_009781 |
| contig00139 | 3382 | 4063 | IncFIB(AP001918)_1 | 0/0 | 100 | 96.6 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00006 | 17801 | 18443 | IncFIB(pB171)_1_pB171 | 0/0 | 100 | 99.2 | AB024946 | IncFIB(pB171)_1_pB171_AB024946 |
| contig00007 | 5323 | 5696 | IncX1_1 | 0/0 | 100 | 98.9 | EU370913 | IncX1_1__EU370913 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00052 | 16919 | 17561 | IncFIB(pB171)_1_pB171 | 0/0 | 100 | 99.4 | AB024946 | IncFIB(pB171)_1_pB171_AB024946 |
| contig00064 | 18329 | 18589 | IncFII(pRSB107)_1_pRSB107 | 0/0 | 100 | 100.0 | AJ851089 | IncFII(pRSB107)_1_pRSB107_AJ851089 |
## [1] "NO PLASMID FOUND!!"
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00069 | 4081 | 4845 | IncY_1 | 0/0 | 100 | 98.8 | K02380 | IncY_1__K02380 |
| contig00085 | 2535 | 3419 | p0111_1 | 0/0 | 100 | 98.6 | AP010962 | p0111_1__AP010962 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00072 | 400 | 632 | Col(BS512)_1 | 0/0 | 100.0 | 100.0 | NC_010656 | Col(BS512)_1__NC_010656 |
| contig00058 | 4076 | 4229 | Col156_1 | 0/0 | 100.0 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00048 | 3426 | 3813 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00050 | 6524 | 7205 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00068 | 3322 | 3557 | IncFII(pAMA1167-NDM-5)_1_pAMA1167-NDM-5 | 0/0 | 90.4 | 97.9 | CP024805.1 | IncFII(pAMA1167-NDM-5)_1_pAMA1167-NDM-5_CP024805.1 |
| contig00046 | 12575 | 12948 | IncX1_1 | 0/0 | 100.0 | 94.9 | EU370913 | IncX1_1__EU370913 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00128 | 431 | 692 | Col(MG828)_1 | 0/0 | 100.0 | 92.8 | NC_008486 | Col(MG828)_1__NC_008486 |
| contig00075 | 11383 | 11493 | Col440I_1 | 0/0 | 97.4 | 92.8 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00070 | 9148 | 9531 | IncFIA_1 | 0/0 | 99.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00105 | 1834 | 2515 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00167 | 428 | 686 | Col(MG828)_1 | 1/1 | 98.8 | 95 | NC_008486 | Col(MG828)_1__NC_008486 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00092 | 4077 | 4230 | Col156_1 | 0/0 | 100 | 94.8 | NC_009781 | Col156_1__NC_009781 |
| contig00071 | 9148 | 9531 | IncFIA_1 | 0/0 | 99 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00074 | 8463 | 9144 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00055 | 1279 | 1990 | IncX4_2 | 0/0 | 100 | 99.0 | FN543504 | IncX4_2__FN543504 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00185 | 3435 | 3994 | IncFIB(K)_1_Kpn3 | 0/0 | 100 | 100 | JN233704 | IncFIB(K)_1_Kpn3_JN233704 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00307 | 400 | 632 | Col(BS512)_1 | 0/0 | 100 | 100.0 | NC_010656 | Col(BS512)_1__NC_010656 |
| contig00183 | 3981 | 4111 | ColRNAI_1 | 1/1 | 100 | 90.1 | DQ298019 | ColRNAI_1__DQ298019 |
| contig00124 | 10533 | 10920 | IncFIA_1 | 0/0 | 100 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00199 | 1834 | 2515 | IncFIB(AP001918)_1 | 0/0 | 100 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00204 | 204 | 464 | IncFII(pRSB107)_1_pRSB107 | 0/0 | 100 | 100.0 | AJ851089 | IncFII(pRSB107)_1_pRSB107_AJ851089 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00085 | 4314 | 4687 | IncX1_1 | 0/0 | 100 | 98.7 | EU370913 | IncX1_1__EU370913 |
| Contig | Start | End | Gene | Gaps | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00081 | 1088 | 1198 | Col440I_1 | 0/0 | 97.4 | 92.8 | CP023920.1 | Col440I_1__CP023920.1 |
| contig00049 | 14298 | 14685 | IncFIA_1 | 0/0 | 100.0 | 99.7 | AP001918 | IncFIA_1__AP001918 |
| contig00069 | 1833 | 2514 | IncFIB(AP001918)_1 | 0/0 | 100.0 | 98.4 | AP001918 | IncFIB(AP001918)_1__AP001918 |
| contig00034 | 38031 | 38291 | IncFII_1 | 0/0 | 100.0 | 100.0 | AY458016 | IncFII_1__AY458016 |
| contig00044 | 15823 | 15964 | IncI1_1_Alpha | 0/0 | 100.0 | 97.9 | AP005147 | IncI1_1_Alpha_AP005147 |
| Field | Description |
|---|---|
| Contig | Contig name where the gene was found |
| Start | Start position of the gene within the contig |
| End | End position of the gene within the contig |
| Gene | Antibiotic resistance gene |
| Coverage | Proportion (%) of the gene covered |
| Identity | Proportion (%) of exact nucleotide matches |
| Accession | Accesion number of the antibiotic resistance gene |
| Product | Antibiotic resistance gene product |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00020 | 74873 | 76301 | + | aslA | 100.0 | 98.5 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00006 | 177711 | 179657 | - | chuA | 100.0 | 99.7 | NP_756170 | (chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 176634 | 177662 | - | chuS | 100.0 | 99.5 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 180299 | 181291 | + | chuT | 100.0 | 99.7 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 183827 | 184819 | + | chuU | 100.0 | 99.5 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 184786 | 185586 | + | chuV | 100.0 | 99.8 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 181311 | 182648 | + | chuW | 100.0 | 99.1 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 182661 | 183155 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 183155 | 183778 | + | chuY | 100.0 | 98.4 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00007 | 138927 | 139382 | + | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00007 | 137524 | 138174 | - | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00007 | 136689 | 137105 | - | csgF | 99.0 | 80.8 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00007 | 135829 | 136662 | - | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00003 | 289871 | 290617 | - | entA | 100.0 | 98.4 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 290617 | 291474 | - | entB | 100.0 | 99.2 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 293108 | 294295 | - | entC | 100.0 | 99.7 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 308753 | 309414 | + | entD | 85.9 | 92.8 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 291488 | 293098 | - | entE | 100.0 | 99.1 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 300972 | 304825 | - | entF | 99.3 | 98.4 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 295432 | 296682 | - | entS | 100.0 | 98.8 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00013 | 22805 | 27055 | - | fdeC | 100.0 | 99.6 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00003 | 306488 | 308728 | + | fepA | 100.0 | 98.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 294472 | 295428 | + | fepB | 100.0 | 99.8 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 298783 | 299598 | + | fepC | 100.0 | 99.4 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 296781 | 297797 | + | fepD | 100.0 | 99.5 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 297794 | 298786 | + | fepG | 100.0 | 99.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 305043 | 306245 | - | fes | 100.0 | 99.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00002 | 319718 | 320323 | - | fimA | 100.0 | 92.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 321822 | 322424 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 318352 | 319077 | - | fimC | 100.0 | 98.5 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 315649 | 318285 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 320748 | 321344 | - | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 315109 | 315642 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 314593 | 315096 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 313671 | 314582 | - | fimH | 100.0 | 97.2 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 319114 | 319653 | - | fimI | 100.0 | 98.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00001 | 512185 | 514206 | - | fyuA | 100.0 | 100.0 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00008 | 187741 | 188571 | + | gspC | 100.0 | 93.9 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 188811 | 190661 | + | gspD | 100.0 | 96.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 190661 | 192154 | + | gspE | 100.0 | 94.9 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 192154 | 193353 | + | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 193394 | 193849 | + | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 193886 | 194416 | + | gspH | 100.0 | 94.7 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 194413 | 194784 | + | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 194817 | 195386 | + | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 195383 | 196360 | + | gspK | 100.0 | 96.6 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 196675 | 197535 | + | gspL | 100.0 | 94.8 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 197651 | 198072 | + | gspM | 99.8 | 93.6 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 517815 | 527306 | - | irp1 | 100.0 | 99.3 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 527396 | 533500 | - | irp2 | 100.0 | 98.9 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00028 | 10165 | 11946 | + | iucA | 100.0 | 99.8 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00028 | 11947 | 12894 | + | iucB | 100.0 | 99.8 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00028 | 12894 | 14636 | + | iucC | 100.0 | 98.2 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00028 | 14633 | 15954 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00028 | 15892 | 18193 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00008 | 211226 | 212902 | - | kpsD | 100.0 | 99.0 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 199132 | 199908 | + | kpsM | 100.0 | 99.9 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 199905 | 200564 | + | kpsT | 100.0 | 100.0 | AAA24047 | (kpsT) KpsT [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00007 | 67818 | 68858 | - | ompA | 100.0 | 99.5 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00028 | 747 | 1060 | - | papB | 99.7 | 98.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig00028 | 1465 | 1698 | + | papI | 100.0 | 94.9 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00059 | 256 | 807 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00028 | 19128 | 23028 | + | sat | 100.0 | 99.5 | NP_755494 | (sat) Aecreted auto transpoter toxin [Sat (VF0231)] [Escherichia coli CFT073] |
| contig00037 | 8438 | 9576 | + | senB | 99.9 | 99.7 | YP_406304 | (senB) enterotoxin [ShET2 (VF0258)] [Shigella flexneri 2a str. 301] |
| contig00013 | 46763 | 50895 | + | vat | 100.0 | 99.7 | NP_752330 | (vat) Haemoglobin protease [Tsh (VF0233)] [Escherichia coli CFT073] |
| contig00013 | 42393 | 43146 | + | yagV/ecpE | 99.7 | 98.4 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 40826 | 42469 | + | yagW/ecpD | 100.0 | 99.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 38311 | 40836 | + | yagX/ecpC | 100.0 | 97.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 37617 | 38285 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 36973 | 37560 | + | yagZ/ecpA | 100.0 | 98.5 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 533691 | 534650 | - | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 514337 | 515914 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 534817 | 536619 | + | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 536606 | 538408 | + | ybtQ | 100.0 | 99.8 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 539709 | 541013 | + | ybtS | 100.0 | 99.8 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 515918 | 516721 | - | ybtT | 100.0 | 99.5 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 516718 | 517818 | - | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 538401 | 539681 | + | ybtX | 100.0 | 99.6 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00013 | 36308 | 36898 | + | ykgK/ecpR | 100.0 | 99.3 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
## Error in read.table("ID008_vfdb.tab", header = T, sep = "\t", dec = ".", : no lines available in input
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00020 | 74873 | 76301 | + | aslA | 100.0 | 98.5 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00006 | 177711 | 179657 | - | chuA | 100.0 | 99.7 | NP_756170 | (chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 176634 | 177662 | - | chuS | 100.0 | 99.5 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 180299 | 181291 | + | chuT | 100.0 | 99.7 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 183827 | 184819 | + | chuU | 100.0 | 99.5 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 184786 | 185586 | + | chuV | 100.0 | 99.8 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 181311 | 182648 | + | chuW | 100.0 | 99.1 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 182661 | 183155 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00006 | 183155 | 183778 | + | chuY | 100.0 | 98.4 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00007 | 138927 | 139382 | + | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00007 | 137524 | 138174 | - | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00007 | 136689 | 137105 | - | csgF | 99.0 | 80.8 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00007 | 135829 | 136662 | - | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00003 | 289871 | 290617 | - | entA | 100.0 | 98.4 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 290617 | 291474 | - | entB | 100.0 | 99.2 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 293108 | 294295 | - | entC | 100.0 | 99.7 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 308753 | 309414 | + | entD | 85.9 | 92.8 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 291488 | 293098 | - | entE | 100.0 | 99.1 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 300972 | 304825 | - | entF | 99.3 | 98.4 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 295432 | 296682 | - | entS | 100.0 | 98.8 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00013 | 22805 | 27055 | - | fdeC | 100.0 | 99.6 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00003 | 306488 | 308728 | + | fepA | 100.0 | 98.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 294472 | 295428 | + | fepB | 100.0 | 99.8 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 298783 | 299598 | + | fepC | 100.0 | 99.4 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 296781 | 297797 | + | fepD | 100.0 | 99.5 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 297794 | 298786 | + | fepG | 100.0 | 99.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00003 | 305043 | 306245 | - | fes | 100.0 | 99.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00002 | 319718 | 320323 | - | fimA | 100.0 | 92.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 321822 | 322424 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 318352 | 319077 | - | fimC | 100.0 | 98.5 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 315649 | 318285 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 320748 | 321344 | - | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 315109 | 315642 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 314593 | 315096 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 313671 | 314582 | - | fimH | 100.0 | 97.2 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 319114 | 319653 | - | fimI | 100.0 | 98.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00001 | 512185 | 514206 | - | fyuA | 100.0 | 100.0 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00008 | 187741 | 188571 | + | gspC | 100.0 | 93.9 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 188811 | 190661 | + | gspD | 100.0 | 96.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 190661 | 192154 | + | gspE | 100.0 | 94.9 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 192154 | 193353 | + | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 193394 | 193849 | + | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 193886 | 194416 | + | gspH | 100.0 | 94.7 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 194413 | 194784 | + | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 194817 | 195386 | + | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 195383 | 196360 | + | gspK | 100.0 | 96.6 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 196675 | 197535 | + | gspL | 100.0 | 94.8 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 197651 | 198072 | + | gspM | 99.8 | 93.6 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 517815 | 527306 | - | irp1 | 100.0 | 99.3 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 527396 | 533500 | - | irp2 | 100.0 | 98.9 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00028 | 10165 | 11946 | + | iucA | 100.0 | 99.8 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00028 | 11947 | 12894 | + | iucB | 100.0 | 99.8 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00028 | 12894 | 14636 | + | iucC | 100.0 | 98.2 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00028 | 14633 | 15954 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00028 | 15892 | 18193 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00008 | 211226 | 212902 | - | kpsD | 100.0 | 99.0 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 199132 | 199908 | + | kpsM | 100.0 | 99.9 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 199905 | 200564 | + | kpsT | 100.0 | 100.0 | AAA24047 | (kpsT) KpsT [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00007 | 67818 | 68858 | - | ompA | 100.0 | 99.5 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00028 | 747 | 1060 | - | papB | 99.7 | 98.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig00028 | 1465 | 1698 | + | papI | 100.0 | 94.9 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00059 | 256 | 807 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00028 | 19128 | 23028 | + | sat | 100.0 | 99.5 | NP_755494 | (sat) Aecreted auto transpoter toxin [Sat (VF0231)] [Escherichia coli CFT073] |
| contig00037 | 8438 | 9576 | + | senB | 99.9 | 99.7 | YP_406304 | (senB) enterotoxin [ShET2 (VF0258)] [Shigella flexneri 2a str. 301] |
| contig00013 | 46763 | 50895 | + | vat | 100.0 | 99.7 | NP_752330 | (vat) Haemoglobin protease [Tsh (VF0233)] [Escherichia coli CFT073] |
| contig00013 | 42393 | 43146 | + | yagV/ecpE | 99.7 | 98.4 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 40826 | 42469 | + | yagW/ecpD | 100.0 | 99.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 38311 | 40836 | + | yagX/ecpC | 100.0 | 97.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 37617 | 38285 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 36973 | 37560 | + | yagZ/ecpA | 100.0 | 98.5 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 533691 | 534650 | - | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 514337 | 515914 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 534817 | 536619 | + | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 536606 | 538408 | + | ybtQ | 100.0 | 99.8 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 539709 | 541013 | + | ybtS | 100.0 | 99.8 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 515918 | 516721 | - | ybtT | 100.0 | 99.5 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 516718 | 517818 | - | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 538401 | 539681 | + | ybtX | 100.0 | 99.6 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00013 | 36308 | 36898 | + | ykgK/ecpR | 100.0 | 99.3 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00214 | 5276 | 6021 | - | entA | 99.6 | 80.3 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00214 | 6031 | 6882 | - | entB | 99.3 | 82.0 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00435 | 165 | 936 | + | fepC | 94.6 | 80.0 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00018 | 17974 | 19044 | - | ompA | 100.0 | 83.3 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00134 | 274 | 1027 | - | yagV/ecpE | 99.7 | 84.3 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00134 | 953 | 2596 | - | yagW/ecpD | 100.0 | 88.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00134 | 2586 | 5111 | - | yagX/ecpC | 100.0 | 87.0 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00134 | 5137 | 5805 | - | yagY/ecpB | 100.0 | 87.7 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00134 | 5867 | 6450 | - | yagZ/ecpA | 99.3 | 90.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00134 | 6524 | 7104 | - | ykgK/ecpR | 98.3 | 86.9 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00011 | 49319 | 50747 | + | aslA | 100.0 | 92.9 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00052 | 8086 | 8541 | + | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00052 | 6681 | 7331 | - | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00052 | 5846 | 6262 | - | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00052 | 4986 | 5819 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00060 | 8729 | 9475 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 9475 | 10332 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 11966 | 13153 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 27797 | 28567 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 10346 | 11956 | - | entE | 100.0 | 95.4 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 20016 | 23869 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 14476 | 15726 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00003 | 8 | 1906 | - | espL1 | 100.0 | 97.5 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 103094 | 105279 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00074 | 6773 | 7827 | + | espR1 | 83.7 | 93.9 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 144243 | 145663 | + | espX1 | 99.9 | 95.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 73298 | 74878 | - | espX4 | 100.0 | 96.5 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 42482 | 43774 | + | espX5 | 100.0 | 96.6 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 105181 | 105977 | - | espY1 | 99.9 | 88.6 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00096 | 4096 | 8344 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00060 | 25532 | 27772 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 13516 | 14472 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 17827 | 18642 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 15825 | 16841 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 16838 | 17830 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00060 | 24087 | 25289 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00130 | 2762 | 3373 | - | fimA | 100.0 | 88.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 263 | 865 | - | fimB | 100.0 | 97.7 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00130 | 1396 | 2121 | - | fimC | 100.0 | 98.6 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00130 | 3800 | 4394 | - | fimE | 99.7 | 99.2 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00070 | 20536 | 21069 | - | fimF | 100.0 | 97.6 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00070 | 20020 | 20523 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00070 | 19098 | 20009 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00130 | 2158 | 2697 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00068 | 7493 | 9274 | - | iucA | 100.0 | 99.9 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00068 | 6545 | 7492 | - | iucB | 100.0 | 99.9 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00068 | 4803 | 6545 | - | iucC | 100.0 | 99.9 | NP_709456 | (iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00068 | 3469 | 4806 | - | iucD | 100.0 | 99.8 | NP_709457 | (iucD) aerobactin synthesis protein IucC lysine 6-monooxygenase [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00068 | 1268 | 3547 | - | iutA | 100.0 | 99.6 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00010 | 74099 | 75139 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00096 | 12030 | 12617 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00096 | 11365 | 11955 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00394 | 1991 | 3419 | + | aslA | 100.0 | 97.2 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00072 | 780 | 1808 | - | chuS | 100.0 | 97.8 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00072 | 4445 | 5437 | + | chuT | 100.0 | 98.5 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00072 | 7973 | 8965 | + | chuU | 100.0 | 99.3 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00072 | 8932 | 9732 | + | chuV | 100.0 | 99.6 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00072 | 5457 | 6794 | + | chuW | 100.0 | 98.1 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00072 | 7301 | 7924 | + | chuY | 100.0 | 97.9 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00972 | 995 | 1450 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00414 | 598 | 1248 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00414 | 1667 | 2083 | + | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00414 | 2110 | 2943 | + | csgG | 100.0 | 82.7 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00082 | 3489 | 4235 | + | entA | 100.0 | 96.5 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00082 | 2632 | 3489 | + | entB | 100.0 | 98.7 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00082 | 1 | 998 | + | entC | 84.0 | 97.0 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00023 | 3909 | 4679 | - | entD | 100.0 | 94.3 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig01564 | 212 | 881 | - | entD | 86.9 | 94.8 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00082 | 1008 | 2618 | + | entE | 100.0 | 98.6 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00023 | 8607 | 12460 | + | entF | 99.3 | 97.3 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00551 | 1305 | 2555 | - | entS | 100.0 | 95.8 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00101 | 6057 | 7955 | - | espL1 | 100.0 | 96.2 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00333 | 2661 | 3911 | + | espR1 | 99.3 | 94.6 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00379 | 2299 | 3438 | - | espR3 | 100.0 | 96.4 | NP_288394 | (espR3) Type III secretion system effector espR3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00154 | 1505 | 3085 | + | espX4 | 100.0 | 94.9 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 6106 | 8514 | + | espY4 | 99.8 | 89.4 | NP_290352 | (espY4) Type III secretion system effector EspY4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00184 | 1435 | 5648 | + | fdeC | 99.1 | 92.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00023 | 4704 | 6944 | - | fepA | 100.0 | 98.0 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00551 | 345 | 1301 | + | fepB | 100.0 | 98.1 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00023 | 13833 | 14648 | - | fepC | 100.0 | 97.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00023 | 15634 | 16482 | - | fepD | 83.5 | 96.7 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00023 | 14645 | 15637 | - | fepG | 100.0 | 95.3 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00023 | 7187 | 8389 | + | fes | 100.0 | 99.3 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00958 | 275 | 1477 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00179 | 598 | 1131 | + | fimF | 100.0 | 97.8 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00179 | 1144 | 1647 | + | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00179 | 1658 | 2569 | + | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 5862 | 7883 | + | fyuA | 100.0 | 100.0 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 42667 | 43497 | - | gspC | 100.0 | 94.8 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 40577 | 42427 | - | gspD | 100.0 | 94.8 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 39084 | 40577 | - | gspE | 100.0 | 94.5 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 37885 | 39084 | - | gspF | 100.0 | 94.1 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 37389 | 37844 | - | gspG | 100.0 | 96.3 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 36822 | 37352 | - | gspH | 100.0 | 97.2 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 36454 | 36825 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 35852 | 36421 | - | gspJ | 100.0 | 96.3 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 34878 | 35855 | - | gspK | 100.0 | 97.2 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 33703 | 34563 | - | gspL | 100.0 | 95.0 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 33166 | 33587 | - | gspM | 99.8 | 95.7 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00031 | 6058 | 7845 | + | iucA | 100.0 | 94.3 | NP_755502 | (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00031 | 7846 | 8793 | + | iucB | 100.0 | 95.7 | NP_755501 | (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00031 | 8793 | 10535 | + | iucC | 100.0 | 96.1 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00031 | 10532 | 11853 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00031 | 11791 | 14092 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00001 | 19000 | 20676 | + | kpsD | 100.0 | 98.0 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 31328 | 32104 | - | kpsM | 100.0 | 92.7 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig01031 | 64 | 1116 | - | ompA | 100.0 | 95.5 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00796 | 957 | 1508 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00072 | 1857 | 3839 | - | shuA | 100.0 | 98.3 | YP_405019 | (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00072 | 6807 | 7301 | + | shuX | 100.0 | 96.2 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00252 | 3222 | 3975 | - | yagV/ecpE | 99.7 | 97.6 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00207 | 2928 | 5453 | + | yagX/ecpC | 100.0 | 98.5 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00207 | 2234 | 2902 | + | yagY/ecpB | 100.0 | 98.8 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00207 | 1589 | 2176 | + | yagZ/ecpA | 100.0 | 99.0 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00769 | 1 | 777 | + | ybtA | 80.9 | 100.0 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 4154 | 5731 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00750 | 1 | 1778 | - | ybtP | 98.6 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig01030 | 1 | 1498 | + | ybtQ | 83.1 | 100.0 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00756 | 815 | 2070 | + | ybtS | 96.2 | 97.5 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 3347 | 4150 | + | ybtT | 100.0 | 99.8 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 2250 | 3350 | + | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00207 | 924 | 1514 | + | ykgK/ecpR | 100.0 | 99.7 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00066 | 9207 | 9512 | - | afaA | 100.0 | 100.0 | CAW30797 | (afaA) fimbrial major subunit AfaA [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00066 | 8172 | 8916 | - | afaB-I | 100.0 | 99.6 | CAW30798 | (afaB-I) chaperone AfaB [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00066 | 5497 | 8079 | - | afaC-I | 100.0 | 99.9 | CAW30799 | (afaC-I) usher AfaC [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00066 | 5038 | 5481 | - | afaD | 100.0 | 100.0 | CAW30800 | (afaD) AfaD [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00066 | 3800 | 4285 | - | afaE-I | 100.0 | 99.8 | CAW30801 | (afaE-I) AFA-I adhesin [Afa/Dr family (VF0212)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00161 | 2910 | 4338 | + | aslA | 100.0 | 92.9 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig01375 | 214 | 1602 | + | aslA | 97.2 | 98.1 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00114 | 6328 | 6651 | + | cesAB | 100.0 | 100.0 | NP_290286 | (cesAB) chaperone for EspA and EspB [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 18724 | 19179 | + | cesD | 100.0 | 99.8 | NP_290276 | (cesD) chaperone for EspB and EspD [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00203 | 3210 | 3617 | + | cesD2 | 100.0 | 99.0 | NP_290253 | (cesD2) chaperone for EspD [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 14838 | 15191 | - | cesL | 100.0 | 99.4 | NP_290270 | (cesL) chaperone for SepL [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 5261 | 5731 | - | cesT | 100.0 | 95.5 | NP_290260 | (cesT) multieffector chaperone [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00101 | 1448 | 3394 | - | chuA | 100.0 | 99.5 | NP_756170 | (chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00101 | 371 | 1399 | - | chuS | 100.0 | 99.0 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00101 | 4036 | 5028 | + | chuT | 100.0 | 99.8 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig01045 | 927 | 1727 | - | chuV | 100.0 | 99.8 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00101 | 5048 | 6385 | + | chuW | 100.0 | 98.9 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00101 | 6398 | 6892 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00101 | 6892 | 7515 | + | chuY | 100.0 | 98.2 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig03350 | 48 | 503 | + | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig01868 | 638 | 1054 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00681 | 1 | 690 | + | csgG | 82.7 | 84.1 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig02263 | 298 | 987 | - | csgG | 82.7 | 83.6 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00066 | 4487 | 4660 | - | draP | 100.0 | 98.8 | AAK16479 | (draP) DraP [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00005 | 2672 | 5201 | - | eae | 89.3 | 90.5 | AAC38392 | (eae) intimin [Intimin (VF0177)] [Escherichia coli O127:H6 str. E2348/69] |
| contig00057 | 3541 | 4287 | + | entA | 100.0 | 96.4 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00057 | 2684 | 3541 | + | entB | 100.0 | 97.9 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00057 | 1 | 1050 | + | entC | 88.4 | 97.0 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00745 | 153 | 1340 | + | entC | 100.0 | 98.7 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00156 | 310 | 971 | + | entD | 85.9 | 96.7 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig01895 | 106 | 876 | - | entD | 100.0 | 94.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00057 | 1060 | 2670 | + | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 3361 | 7214 | + | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00957 | 963 | 2174 | - | entS | 96.9 | 96.0 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig01765 | 55 | 1266 | - | entS | 96.9 | 97.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00005 | 17172 | 18710 | + | escC | 100.0 | 99.6 | NP_290275 | (escC) Type III secretion system secretin EscC [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 751 | 1971 | + | escD | 100.0 | 98.7 | NP_290258 | (escD) Type III secretion system outer MS ring protein EscD [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00114 | 6106 | 6324 | + | escE | 100.0 | 98.6 | NP_290287 | (escE) chaperone for EscF [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00203 | 3653 | 3874 | + | escF | 100.0 | 100.0 | NP_290252 | (escF) Type III secretion system needle filament protein EscF [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00203 | 3880 | 4158 | + | escG | 100.0 | 97.8 | NP_290251 | (escG) chaperone for EscF [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 15708 | 16136 | + | escI | 100.0 | 99.3 | NP_290272 | (escI) Type III secretion system inner rod component EscI [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 16139 | 16711 | + | escJ | 100.0 | 99.5 | NP_290273 | (escJ) Type III secretion system inner MS ring protein EscJ [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00114 | 7273 | 7795 | + | escL | 85.0 | 99.4 | NP_290284 | (escL) negative regulator EscL stator protein [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 11490 | 12830 | - | escN | 100.0 | 99.5 | NP_290268 | (escN) ATPase EscN [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 11110 | 11487 | - | escO | 100.0 | 99.7 | NP_290267 | (escO) positive regulator EscO [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 10701 | 10976 | - | escP | 100.0 | 99.3 | NP_290266 | (escP) Type III secretion system needle length regulator EscP [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 23129 | 23782 | - | escR | 100.0 | 99.8 | NP_290283 | (escR) Type III secretion systemminor export apparatus protein EscR [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 22860 | 23129 | - | escS | 100.0 | 100.0 | NP_290282 | (escS) Type III secretion systemminor export apparatus protein EscS [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 22084 | 22860 | - | escT | 100.0 | 99.6 | NP_290281 | (escT) Type III secretion system minor export apparatus protein EscT [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 21054 | 22091 | - | escU | 100.0 | 99.6 | NP_290280 | (escU) Type III secretion system export apparatus switch protein EscU [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 12814 | 14841 | - | escV | 100.0 | 99.8 | NP_290269 | (escV) Type III secretion system major export apparatus protein [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00203 | 484 | 1062 | + | espA | 100.0 | 84.6 | NP_290256 | (espA) Type III secretion system translocator protein EspA [EspA (VF0198)] [Escherichia coli O157:H7 str. EDL933] |
| contig00203 | 2238 | 3203 | + | espB | 100.0 | 99.9 | AAC38396 | (espB) EspB [EspB (VF0179)] [Escherichia coli O127:H6 str. E2348/69] |
| contig00203 | 1075 | 2217 | + | espD | 100.0 | 99.7 | AAC38395 | (espD) EspD [EspD (VF0180)] [Escherichia coli O127:H6 str. E2348/69] |
| contig00203 | 4243 | 4863 | + | espF | 100.0 | 99.7 | AAC38400 | (espF) EspF [EspF (VF0182)] [Escherichia coli O127:H6 str. E2348/69] |
| contig00114 | 3255 | 4451 | - | espG | 100.0 | 98.5 | NP_290289 | (espG) Type III secretion system effector EspG GTPase activating protein [EspG (VF0201)] [Escherichia coli O157:H7 str. EDL933] |
| contig00071 | 606 | 1967 | + | espK | 100.0 | 92.1 | NP_287316 | (espK) Type III secretion system effector EspK [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00778 | 254 | 2152 | + | espL1 | 100.0 | 96.4 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00071 | 2344 | 5157 | - | espN | 100.0 | 99.9 | NP_287312 | (espN) Type III secretion system effector EspN [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00388 | 1875 | 2929 | + | espR1 | 83.7 | 94.0 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00252 | 2957 | 4537 | + | espX4 | 99.9 | 94.1 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00295 | 1566 | 2858 | - | espX5 | 100.0 | 96.5 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00071 | 6337 | 8286 | - | espX7/nleL | 100.0 | 99.7 | NP_287310 | (espX7/nleL) Type III secretion system effector NleL putative E3 ubiquitin ligase [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 20599 | 21057 | + | etgA | 100.0 | 99.1 | NP_290279 | (etgA) T3SS-associated peptidoglycan lytic enzyme [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00957 | 3 | 959 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 8588 | 9403 | - | fepC | 100.0 | 97.4 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 10389 | 11300 | - | fepD | 89.7 | 95.6 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig01231 | 1 | 918 | + | fepD | 90.3 | 97.6 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 9400 | 10392 | - | fepG | 100.0 | 94.5 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig01231 | 915 | 1767 | + | fepG | 85.9 | 98.0 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 1941 | 3143 | + | fes | 100.0 | 96.5 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00632 | 1561 | 2172 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig02935 | 1 | 538 | + | fimA | 88.8 | 89.8 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00632 | 195 | 920 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig02144 | 397 | 930 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig02871 | 146 | 679 | - | fimF | 100.0 | 96.6 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00312 | 109 | 1020 | + | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00632 | 957 | 1496 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00022 | 9656 | 10486 | - | gspC | 100.0 | 96.5 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 7566 | 9416 | - | gspD | 100.0 | 97.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 6073 | 7566 | - | gspE | 100.0 | 96.5 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00452 | 142 | 1635 | + | gspE | 100.0 | 95.0 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 4874 | 6073 | - | gspF | 100.0 | 95.9 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00452 | 1635 | 2834 | + | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 4378 | 4833 | - | gspG | 100.0 | 95.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00452 | 2875 | 3330 | + | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 3811 | 4341 | - | gspH | 100.0 | 95.5 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 3443 | 3814 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00808 | 1961 | 2332 | - | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 2841 | 3410 | - | gspJ | 100.0 | 96.7 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00808 | 1359 | 1928 | - | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 1867 | 2844 | - | gspK | 100.0 | 97.8 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00808 | 385 | 1362 | - | gspK | 100.0 | 96.6 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 692 | 1552 | - | gspL | 100.0 | 97.1 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00022 | 154 | 576 | - | gspM | 100.0 | 97.9 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00421 | 2643 | 3064 | - | gspM | 99.8 | 92.9 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00025 | 5316 | 7097 | - | iucA | 100.0 | 99.8 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00025 | 4368 | 5315 | - | iucB | 100.0 | 99.8 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00025 | 2626 | 4368 | - | iucC | 100.0 | 98.2 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00025 | 1308 | 2629 | - | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00079 | 3333 | 5009 | + | kpsD | 100.0 | 98.3 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00421 | 808 | 1584 | - | kpsM | 100.0 | 94.7 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00005 | 7835 | 8446 | - | map | 100.0 | 82.3 | NP_290262 | (map) Type III secretion system effector Map Rho guanine exchange factor [Map (VF0195)] [Escherichia coli O157:H7 str. EDL933] |
| contig00190 | 3576 | 4901 | + | nleA/espI | 100.0 | 89.5 | NP_287961 | (nleA/espI) Type III secretion system effector NleA [NleA/EspI (VF0338)] [Escherichia coli O157:H7 str. EDL933] |
| contig00363 | 3097 | 4077 | - | nleB2 | 100.0 | 100.0 | NP_286532 | (nleB2) Type III secretion system effector NleB2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00363 | 920 | 1489 | - | nleF | 100.0 | 94.9 | NP_287958 | (nleF) Type III secretion system effector NleF caspase inhibitor [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00363 | 1544 | 2455 | - | nleH2 | 99.9 | 91.6 | NP_287959 | (nleH2) Type III secretion system effector NleH2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig01215 | 745 | 1058 | - | papB | 99.7 | 98.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig01215 | 1463 | 1696 | + | papI | 100.0 | 94.9 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig01784 | 255 | 806 | + | papX | 100.0 | 97.6 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00065 | 6246 | 7384 | + | senB | 99.9 | 99.7 | YP_406304 | (senB) enterotoxin [ShET2 (VF0258)] [Shigella flexneri 2a str. 301] |
| contig00005 | 16717 | 17172 | + | sepD | 100.0 | 98.7 | NP_290274 | (sepD) Type III secretion system secretion switch protein SepD [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 9821 | 10738 | - | sepQ/escQ | 100.0 | 95.2 | NP_290265 | (sepQ/escQ) Type III secetion system C ring protein EscQ [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 15376 | 15675 | + | sepZ/espZ | 100.0 | 99.7 | NP_290271 | (sepZ/espZ) Type III secretion system effector EspZ [TTSS (VF0191)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 893 | 1646 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00496 | 1066 | 3401 | + | yagX/ecpC | 92.5 | 98.6 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00496 | 372 | 1040 | + | yagY/ecpB | 100.0 | 98.2 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig03163 | 54 | 661 | + | yagY/ecpB | 90.9 | 97.9 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig01722 | 1 | 1287 | + | ybtE | 81.6 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00880 | 744 | 2024 | - | ybtX | 100.0 | 97.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00885 | 744 | 2024 | - | ybtX | 100.0 | 99.7 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00150 | 6171 | 6761 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00061 | 7875 | 8619 | - | afaB-I | 100.0 | 98.2 | CAW30798 | (afaB-I) chaperone AfaB [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00061 | 5200 | 7782 | - | afaC-I | 100.0 | 99.0 | CAW30799 | (afaC-I) usher AfaC [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00025 | 49693 | 50148 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00025 | 50902 | 51552 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00025 | 51971 | 52387 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00025 | 52414 | 53247 | + | csgG | 100.0 | 83.1 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00061 | 9989 | 10216 | + | daaF | 100.0 | 100.0 | AAA23662 | (daaF) DaaF protein [F1845 fimbrial adhesin (AI016)] [Escherichia coli str. C1845] |
| contig00061 | 8880 | 9185 | - | draA | 100.0 | 100.0 | AAK16475 | (draA) cytoplamic protein DraA [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00061 | 4741 | 5184 | - | draD | 100.0 | 99.8 | AAK16478 | (draD) DraD periplasmic protein [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00061 | 3443 | 4002 | - | draE2 | 99.6 | 99.6 | AAB65153 | (draE2) Dr-II structural adhesin precursor [Afa/Dr family (VF0212)] [Escherichia coli EC7372] |
| contig00061 | 4189 | 4362 | - | draP | 100.0 | 99.4 | AAK16479 | (draP) DraP [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00012 | 99201 | 99947 | - | entA | 100.0 | 96.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 99947 | 100804 | - | entB | 100.0 | 97.5 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 102438 | 103625 | - | entC | 100.0 | 97.4 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 118270 | 119040 | + | entD | 100.0 | 94.0 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 100818 | 102428 | - | entE | 100.0 | 96.0 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 110513 | 114342 | - | entF | 98.7 | 95.9 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 104948 | 106198 | - | entS | 100.0 | 95.6 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00017 | 5445 | 7343 | - | espL1 | 100.0 | 94.8 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00051 | 24864 | 25919 | + | espR1 | 83.8 | 94.2 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00008 | 116391 | 117812 | + | espX1 | 100.0 | 94.7 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 62207 | 63787 | - | espX4 | 99.9 | 92.9 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 31357 | 32649 | + | espX5 | 100.0 | 95.6 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 28661 | 32886 | + | fdeC | 99.4 | 91.0 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00012 | 116005 | 118245 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 103988 | 104944 | + | fepB | 100.0 | 97.4 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 108299 | 109114 | + | fepC | 100.0 | 97.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 106297 | 107313 | + | fepD | 100.0 | 96.4 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 107310 | 108302 | + | fepG | 100.0 | 94.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 114560 | 115762 | - | fes | 100.0 | 96.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00053 | 25212 | 25817 | - | fimA | 100.0 | 92.9 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00054 | 1111 | 1713 | - | fimB | 100.0 | 97.8 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 23846 | 24571 | - | fimC | 100.0 | 98.2 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 21143 | 23779 | - | fimD | 100.0 | 98.8 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00054 | 39 | 633 | - | fimE | 99.7 | 98.8 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20603 | 21136 | - | fimF | 100.0 | 97.8 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20087 | 20590 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 19165 | 20076 | - | fimH | 100.0 | 97.5 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 24608 | 25147 | - | fimI | 100.0 | 98.5 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00009 | 97658 | 98488 | - | gspC | 100.0 | 95.0 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 95568 | 97418 | - | gspD | 100.0 | 97.3 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 94075 | 95568 | - | gspE | 100.0 | 96.1 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 92876 | 94075 | - | gspF | 100.0 | 96.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 92380 | 92835 | - | gspG | 100.0 | 95.6 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 91813 | 92343 | - | gspH | 100.0 | 96.0 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 91445 | 91816 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 90843 | 91412 | - | gspJ | 100.0 | 97.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 89869 | 90846 | - | gspK | 100.0 | 97.8 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 88694 | 89554 | - | gspL | 100.0 | 97.0 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00009 | 88156 | 88578 | - | gspM | 100.0 | 94.1 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 205158 | 206210 | - | ompA | 100.0 | 94.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00013 | 18802 | 19555 | - | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 19479 | 21122 | - | yagW/ecpD | 100.0 | 98.6 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 21112 | 23637 | - | yagX/ecpC | 100.0 | 98.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 23663 | 24331 | - | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 24389 | 24976 | - | yagZ/ecpA | 100.0 | 99.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 25051 | 25641 | - | ykgK/ecpR | 100.0 | 97.6 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00071 | 5613 | 6357 | - | afaB-I | 100.0 | 98.2 | CAW30798 | (afaB-I) chaperone AfaB [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00071 | 2938 | 5520 | - | afaC-I | 100.0 | 99.0 | CAW30799 | (afaC-I) usher AfaC [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00006 | 132424 | 132879 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 133633 | 134283 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 134702 | 135118 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 135145 | 135978 | + | csgG | 100.0 | 83.1 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00071 | 7727 | 7954 | + | daaF | 100.0 | 100.0 | AAA23662 | (daaF) DaaF protein [F1845 fimbrial adhesin (AI016)] [Escherichia coli str. C1845] |
| contig00071 | 6618 | 6923 | - | draA | 100.0 | 100.0 | AAK16475 | (draA) cytoplamic protein DraA [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00071 | 2479 | 2922 | - | draD | 100.0 | 99.8 | AAK16478 | (draD) DraD periplasmic protein [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00071 | 1181 | 1740 | - | draE2 | 99.6 | 99.6 | AAB65153 | (draE2) Dr-II structural adhesin precursor [Afa/Dr family (VF0212)] [Escherichia coli EC7372] |
| contig00071 | 1927 | 2100 | - | draP | 100.0 | 99.4 | AAK16479 | (draP) DraP [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00040 | 23172 | 23918 | - | entA | 100.0 | 96.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 23918 | 24775 | - | entB | 100.0 | 97.5 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 26409 | 27596 | - | entC | 100.0 | 97.4 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 42241 | 43011 | + | entD | 100.0 | 94.0 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 24789 | 26399 | - | entE | 100.0 | 96.0 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 34484 | 38313 | - | entF | 98.7 | 95.9 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 28919 | 30169 | - | entS | 100.0 | 95.6 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00033 | 26358 | 28256 | + | espL1 | 100.0 | 94.8 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00042 | 14590 | 15645 | - | espR1 | 83.8 | 94.2 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 50896 | 52317 | + | espX1 | 100.0 | 94.7 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 62182 | 63762 | - | espX4 | 99.9 | 92.9 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 31332 | 32624 | + | espX5 | 100.0 | 95.6 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 83053 | 87278 | - | fdeC | 99.4 | 91.0 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00040 | 39976 | 42216 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 27959 | 28915 | + | fepB | 100.0 | 97.4 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 32270 | 33085 | + | fepC | 100.0 | 97.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 30268 | 31284 | + | fepD | 100.0 | 96.4 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 31281 | 32273 | + | fepG | 100.0 | 94.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 38531 | 39733 | - | fes | 100.0 | 96.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00019 | 77242 | 77847 | - | fimA | 100.0 | 92.9 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00057 | 25726 | 26328 | + | fimB | 100.0 | 97.8 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00019 | 75876 | 76601 | - | fimC | 100.0 | 98.2 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00019 | 73173 | 75809 | - | fimD | 100.0 | 98.8 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00057 | 26806 | 27400 | + | fimE | 99.7 | 98.8 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00019 | 72633 | 73166 | - | fimF | 100.0 | 97.8 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00019 | 72117 | 72620 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00019 | 71195 | 72106 | - | fimH | 100.0 | 97.5 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00019 | 76638 | 77177 | - | fimI | 100.0 | 98.5 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00004 | 136126 | 136956 | - | gspC | 100.0 | 95.0 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 134036 | 135886 | - | gspD | 100.0 | 97.3 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 132543 | 134036 | - | gspE | 100.0 | 96.1 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 131344 | 132543 | - | gspF | 100.0 | 96.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 130848 | 131303 | - | gspG | 100.0 | 95.6 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 130281 | 130811 | - | gspH | 100.0 | 96.0 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 129913 | 130284 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 129311 | 129880 | - | gspJ | 100.0 | 97.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 128337 | 129314 | - | gspK | 100.0 | 97.8 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 127162 | 128022 | - | gspL | 100.0 | 97.0 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 126624 | 127046 | - | gspM | 100.0 | 94.1 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 83583 | 84635 | - | ompA | 100.0 | 94.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00052 | 22274 | 23027 | - | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 22951 | 24594 | - | yagW/ecpD | 100.0 | 98.6 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 24584 | 27109 | - | yagX/ecpC | 100.0 | 98.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 27135 | 27803 | - | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 27861 | 28448 | - | yagZ/ecpA | 100.0 | 99.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 28523 | 29113 | - | ykgK/ecpR | 100.0 | 97.6 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00033 | 254 | 1682 | - | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00002 | 148976 | 149431 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00002 | 147569 | 148219 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00002 | 146734 | 147150 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00002 | 145874 | 146707 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00045 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00021 | 15786 | 17686 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00011 | 102778 | 104964 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00047 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00008 | 69187 | 70608 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00011 | 72982 | 74562 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00011 | 42191 | 43483 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00008 | 108754 | 109565 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 59008 | 63256 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00045 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00045 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00063 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00063 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00063 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00063 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00063 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00063 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00063 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 31681 | 33702 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 18581 | 28072 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 12386 | 18493 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 65175 | 66215 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00036 | 8091 | 8844 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00036 | 6524 | 8167 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00036 | 4009 | 6534 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00036 | 3315 | 3983 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00036 | 2670 | 3257 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00031 | 11236 | 12195 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 29973 | 31550 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 9267 | 11069 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 7478 | 9280 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 4873 | 6177 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 29166 | 29969 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 28069 | 29169 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 6205 | 7485 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 2005 | 2595 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00013 | 34713 | 36141 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00030 | 6293 | 6748 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00030 | 4886 | 5536 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00030 | 4051 | 4467 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00030 | 3191 | 4024 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00041 | 19920 | 20666 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 20666 | 21523 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 23157 | 24344 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 38988 | 39758 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 21537 | 23147 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 31207 | 35060 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 25667 | 26917 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00022 | 23929 | 25829 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00075 | 14097 | 16283 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00057 | 25069 | 26122 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 50505 | 51926 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00055 | 13970 | 15550 | + | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 40679 | 41971 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00045 | 17064 | 17875 | - | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 33538 | 37786 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00041 | 36723 | 38963 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 24707 | 25663 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 29018 | 29833 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 27016 | 28032 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 28029 | 29021 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 35278 | 36480 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00069 | 25027 | 25638 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00069 | 23661 | 24386 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00069 | 20958 | 23594 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00069 | 20418 | 20951 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00069 | 19902 | 20405 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00069 | 18980 | 19891 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00069 | 24423 | 24962 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00025 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00007 | 14845 | 15885 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00010 | 46897 | 47650 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 45330 | 46973 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 42815 | 45340 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 42121 | 42789 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 41476 | 42063 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00010 | 40811 | 41401 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00016 | 74847 | 76275 | + | aslA | 100.0 | 98.5 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00005 | 177711 | 179657 | - | chuA | 100.0 | 99.7 | NP_756170 | (chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 176634 | 177662 | - | chuS | 100.0 | 99.5 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 180299 | 181291 | + | chuT | 100.0 | 99.7 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 183827 | 184819 | + | chuU | 100.0 | 99.5 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 184786 | 185586 | + | chuV | 100.0 | 99.6 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 181311 | 182648 | + | chuW | 100.0 | 99.1 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 182661 | 183155 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00005 | 183155 | 183778 | + | chuY | 100.0 | 98.4 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00011 | 80832 | 81287 | - | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00011 | 82040 | 82690 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00011 | 83109 | 83525 | + | csgF | 99.0 | 80.8 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00011 | 83552 | 84385 | + | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00037 | 31204 | 31950 | - | entA | 100.0 | 98.4 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 31950 | 32807 | - | entB | 100.0 | 99.2 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 34441 | 35628 | - | entC | 100.0 | 99.7 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 4966 | 5627 | + | entD | 85.9 | 92.8 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 32821 | 34431 | - | entE | 100.0 | 99.1 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 36765 | 38015 | - | entS | 100.0 | 98.8 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00050 | 22805 | 26613 | - | fdeC | 89.6 | 99.6 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00041 | 2701 | 4941 | + | fepA | 100.0 | 98.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 35805 | 36761 | + | fepB | 100.0 | 99.8 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 40116 | 40931 | + | fepC | 100.0 | 99.4 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 38114 | 39130 | + | fepD | 100.0 | 99.5 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00037 | 39127 | 40119 | + | fepG | 100.0 | 99.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00041 | 1256 | 2458 | - | fes | 100.0 | 99.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00013 | 126236 | 126841 | - | fimA | 100.0 | 92.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00033 | 1122 | 1724 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 124870 | 125595 | - | fimC | 100.0 | 98.5 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 122167 | 124803 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00033 | 48 | 644 | - | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 121627 | 122160 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 121111 | 121614 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 120189 | 121100 | - | fimH | 100.0 | 97.2 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 125632 | 126171 | - | fimI | 100.0 | 98.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00018 | 86035 | 88056 | - | fyuA | 100.0 | 100.0 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00004 | 170339 | 171169 | + | gspC | 100.0 | 93.9 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 171409 | 173259 | + | gspD | 100.0 | 96.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 173259 | 174752 | + | gspE | 100.0 | 94.9 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 174752 | 175951 | + | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 175992 | 176447 | + | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 176484 | 177014 | + | gspH | 100.0 | 94.7 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 177011 | 177382 | + | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 177415 | 177984 | + | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 177981 | 178958 | + | gspK | 100.0 | 96.6 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 179273 | 180133 | + | gspL | 100.0 | 94.8 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 180249 | 180670 | + | gspM | 99.8 | 93.6 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00021 | 3195 | 12686 | - | irp1 | 100.0 | 99.3 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 12776 | 18880 | - | irp2 | 100.0 | 98.9 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00053 | 10165 | 11946 | + | iucA | 100.0 | 99.8 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00053 | 11947 | 12894 | + | iucB | 100.0 | 99.8 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00053 | 12894 | 14636 | + | iucC | 100.0 | 98.2 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00053 | 14633 | 15954 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00053 | 15892 | 18193 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00004 | 193824 | 195500 | - | kpsD | 100.0 | 99.0 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00004 | 181730 | 182506 | + | kpsM | 100.0 | 99.9 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00004 | 182503 | 183162 | + | kpsT | 100.0 | 100.0 | AAA24047 | (kpsT) KpsT [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 140930 | 141970 | - | ompA | 100.0 | 99.5 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00053 | 747 | 1060 | - | papB | 99.7 | 98.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig00053 | 1465 | 1698 | + | papI | 100.0 | 94.9 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00098 | 256 | 807 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00082 | 151 | 4051 | + | sat | 100.0 | 99.5 | NP_755494 | (sat) Aecreted auto transpoter toxin [Sat (VF0231)] [Escherichia coli CFT073] |
| contig00067 | 8438 | 9576 | + | senB | 99.9 | 99.7 | YP_406304 | (senB) enterotoxin [ShET2 (VF0258)] [Shigella flexneri 2a str. 301] |
| contig00038 | 20107 | 24238 | + | vat | 100.0 | 99.7 | NP_752330 | (vat) Haemoglobin protease [Tsh (VF0233)] [Escherichia coli CFT073] |
| contig00038 | 15737 | 16490 | + | yagV/ecpE | 99.7 | 98.4 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00038 | 14170 | 15813 | + | yagW/ecpD | 100.0 | 99.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00038 | 11655 | 14180 | + | yagX/ecpC | 100.0 | 97.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00038 | 10961 | 11629 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00038 | 10317 | 10904 | + | yagZ/ecpA | 100.0 | 98.5 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 19071 | 20030 | - | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 1 | 1294 | - | ybtE | 82.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 20197 | 21999 | + | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 21986 | 23788 | + | ybtQ | 100.0 | 99.8 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 25089 | 26393 | + | ybtS | 100.0 | 99.8 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 1298 | 2101 | - | ybtT | 100.0 | 99.5 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 2098 | 3198 | - | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00021 | 23781 | 25061 | + | ybtX | 100.0 | 99.6 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 9652 | 10242 | + | ykgK/ecpR | 100.0 | 99.3 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00030 | 15483 | 16911 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00019 | 7466 | 7921 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00019 | 6061 | 6711 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00019 | 5226 | 5642 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00019 | 4366 | 5199 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 26547 | 27293 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 27293 | 28150 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 29784 | 30971 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 45615 | 46385 | + | entD | 100.0 | 95.1 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 28164 | 29774 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 37834 | 41687 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 32294 | 33544 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00009 | 15959 | 17858 | - | espL1 | 100.0 | 97.6 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 91954 | 94140 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00060 | 15211 | 16264 | - | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 190820 | 191954 | - | espR4 | 99.5 | 84.3 | NP_288396 | (espR4) Type III secretion system effector espR4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 144042 | 145463 | + | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 62158 | 63738 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 31367 | 32659 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 105100 | 105896 | - | espY1 | 99.9 | 88.7 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 4769 | 9017 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00032 | 43350 | 45590 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 31334 | 32290 | + | fepB | 100.0 | 97.4 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 35645 | 36460 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 33643 | 34659 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 34656 | 35648 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00032 | 41905 | 43107 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00014 | 53037 | 53648 | - | fimA | 100.0 | 88.4 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 55146 | 55748 | - | fimB | 100.0 | 98.0 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 51671 | 52396 | - | fimC | 100.0 | 98.6 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 48968 | 51604 | - | fimD | 100.0 | 98.5 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 54075 | 54669 | - | fimE | 99.7 | 99.3 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 48428 | 48961 | - | fimF | 100.0 | 97.8 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 47912 | 48415 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 46990 | 47901 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 52433 | 52972 | - | fimI | 100.0 | 98.9 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00007 | 134529 | 135359 | - | gspC | 100.0 | 94.7 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 132439 | 134289 | - | gspD | 100.0 | 96.0 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 130946 | 132439 | - | gspE | 100.0 | 96.9 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 129747 | 130946 | - | gspF | 100.0 | 96.0 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 129251 | 129706 | - | gspG | 100.0 | 95.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 128684 | 129214 | - | gspH | 100.0 | 95.5 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 128316 | 128687 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 127714 | 128283 | - | gspJ | 100.0 | 96.7 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 126740 | 127717 | - | gspK | 100.0 | 97.0 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 125565 | 126425 | - | gspL | 100.0 | 97.1 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 125027 | 125449 | - | gspM | 100.0 | 98.3 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 237168 | 238208 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00040 | 18126 | 18879 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 16559 | 18202 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 14044 | 16569 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 13350 | 14018 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 12705 | 13292 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 12040 | 12630 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00029 | 16207 | 17635 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00004 | 135844 | 136299 | - | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00004 | 137054 | 137704 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00004 | 138123 | 138539 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00004 | 138566 | 139399 | + | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00071 | 19198 | 19944 | + | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 18341 | 19198 | + | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 15520 | 16707 | + | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 106 | 876 | - | entD | 100.0 | 94.3 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 16717 | 18327 | + | entE | 100.0 | 95.4 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 4804 | 8657 | + | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 12947 | 14197 | + | entS | 100.0 | 95.5 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00014 | 1 | 1859 | + | espL1 | 97.8 | 97.6 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00020 | 17395 | 18975 | - | espX4 | 99.9 | 94.1 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00055 | 19768 | 21060 | + | espX5 | 100.0 | 96.6 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00071 | 901 | 3141 | - | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 14201 | 15157 | - | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 10031 | 10846 | - | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 11832 | 12848 | - | fepD | 100.0 | 96.2 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 10843 | 11835 | - | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00071 | 3384 | 4586 | + | fes | 100.0 | 96.6 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00061 | 25661 | 28297 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 25121 | 25654 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 24605 | 25108 | - | fimG | 100.0 | 98.2 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 23683 | 24594 | - | fimH | 100.0 | 97.2 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00056 | 29400 | 31421 | + | fyuA | 100.0 | 99.6 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 16300 | 25791 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 10105 | 16212 | + | irp2 | 100.0 | 99.6 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 29720 | 30772 | + | ompA | 100.0 | 95.6 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00097 | 3621 | 4559 | - | pla | 100.0 | 98.3 | NP_395233 | (pla) plasminogen activator protease precursor [Pla (VF0139)] [Yersinia pestis CO92] |
| contig00056 | 8955 | 9914 | + | ybtA | 100.0 | 99.3 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 27692 | 29269 | + | ybtE | 100.0 | 99.9 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 6986 | 8788 | - | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 5197 | 6999 | - | ybtQ | 100.0 | 99.6 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 2592 | 3896 | - | ybtS | 100.0 | 99.5 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 26885 | 27688 | + | ybtT | 100.0 | 99.6 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 25788 | 26888 | + | ybtU | 100.0 | 99.9 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00056 | 3924 | 5204 | - | ybtX | 100.0 | 99.6 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00816 | 681 | 1331 | + | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig02160 | 275 | 691 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig01530 | 11 | 757 | + | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00746 | 403 | 1499 | - | entS | 87.7 | 95.1 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00565 | 1 | 1436 | + | espX4 | 90.8 | 93.7 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00071 | 1520 | 2245 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00201 | 1174 | 1707 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00201 | 658 | 1161 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00071 | 2282 | 2821 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00782 | 36 | 1340 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00091 | 411 | 1214 | - | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00091 | 1211 | 2311 | - | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00018 | 49173 | 50601 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00038 | 6313 | 6768 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00038 | 4906 | 5556 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00038 | 4071 | 4487 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00038 | 3211 | 4044 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00049 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00037 | 1 | 1621 | + | espL1 | 85.3 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 63986 | 66172 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 24678 | 25731 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 46284 | 47705 | + | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 34190 | 35770 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 3399 | 4691 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 7327 | 8138 | - | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 33602 | 37850 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00049 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00049 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00061 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00061 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00036 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 103766 | 104806 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00022 | 46961 | 47714 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 45394 | 47037 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 42879 | 45404 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 42185 | 42853 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 41540 | 42127 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00036 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00036 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00022 | 40875 | 41465 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00026 | 24374 | 25802 | - | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 301680 | 302135 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00001 | 300273 | 300923 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00001 | 299438 | 299854 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00001 | 298578 | 299411 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00052 | 8404 | 9150 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 9150 | 10007 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 11641 | 12828 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 27472 | 28242 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 10021 | 11631 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 19691 | 23544 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 14151 | 15401 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00024 | 23931 | 25831 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 102815 | 105001 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00042 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 50505 | 51926 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 73019 | 74599 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 42228 | 43520 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 90072 | 90883 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00014 | 58848 | 63096 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00052 | 25207 | 27447 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 13191 | 14147 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 17502 | 18317 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 15500 | 16516 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 16513 | 17505 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00052 | 23762 | 24964 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00053 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 217879 | 218919 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00014 | 72207 | 72960 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00014 | 70640 | 72283 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00014 | 68125 | 70650 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00014 | 67431 | 68099 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00014 | 66786 | 67373 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00035 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00014 | 66121 | 66711 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00021 | 49173 | 50601 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00035 | 9327 | 9782 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 7920 | 8570 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 7085 | 7501 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 6225 | 7058 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00044 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00024 | 23931 | 25831 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 91986 | 94172 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00045 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 69187 | 70608 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 62190 | 63770 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 31399 | 32691 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 108754 | 109565 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 204827 | 209075 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00044 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00055 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00055 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00055 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00055 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00055 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00055 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00055 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00033 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 219469 | 220509 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00002 | 218186 | 218939 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 216619 | 218262 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 214104 | 216629 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 213410 | 214078 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 212765 | 213352 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00033 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 212100 | 212690 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00023 | 49173 | 50601 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00035 | 6471 | 6926 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 5064 | 5714 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 4229 | 4645 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 3369 | 4202 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00044 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00026 | 23930 | 25830 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 7562 | 9748 | - | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00045 | 25726 | 26779 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 69187 | 70608 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 37964 | 39544 | + | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 69043 | 70335 | - | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 108754 | 109565 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 33539 | 37787 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00044 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00058 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00058 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00058 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00058 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00058 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00058 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00058 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00054 | 20731 | 22752 | - | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00060 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 177939 | 178979 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00025 | 46898 | 47651 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 45331 | 46974 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 42816 | 45341 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 42122 | 42790 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 41477 | 42064 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00060 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00054 | 22883 | 24460 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00060 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00060 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00060 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00054 | 24464 | 25267 | - | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00054 | 25264 | 26364 | - | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00060 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 40812 | 41402 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00018 | 75528 | 76955 | + | aslA | 99.9 | 98.0 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00009 | 179716 | 181662 | - | chuA | 100.0 | 99.8 | NP_756170 | (chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 178639 | 179667 | - | chuS | 100.0 | 99.5 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 182330 | 183322 | + | chuT | 100.0 | 99.5 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 185858 | 186850 | + | chuU | 100.0 | 99.6 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 186817 | 187617 | + | chuV | 100.0 | 99.6 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 183342 | 184679 | + | chuW | 100.0 | 99.1 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 184692 | 185186 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00009 | 185186 | 185809 | + | chuY | 100.0 | 99.5 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00042 | 7651 | 10695 | + | cnf1 | 100.0 | 99.6 | CAA50007 | (cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0240)] [Escherichia coli str. E-B35] |
| contig00021 | 88421 | 88876 | - | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 89630 | 90280 | + | csgD | 100.0 | 81.4 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 90699 | 91115 | + | csgF | 99.0 | 81.7 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 91142 | 91975 | + | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00016 | 97918 | 98664 | - | entA | 100.0 | 98.5 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 98664 | 99521 | - | entB | 100.0 | 99.3 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 101155 | 102342 | - | entC | 100.0 | 99.8 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 116808 | 117578 | + | entD | 100.0 | 97.0 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 99535 | 101145 | - | entE | 100.0 | 99.2 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 109019 | 112872 | - | entF | 99.3 | 98.2 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 103479 | 104729 | - | entS | 100.0 | 96.3 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00004 | 151801 | 156051 | + | fdeC | 100.0 | 99.9 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00016 | 114534 | 116783 | + | fepA | 100.0 | 98.1 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 102519 | 103475 | + | fepB | 100.0 | 99.6 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 106830 | 107645 | + | fepC | 100.0 | 100.0 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 104828 | 105844 | + | fepD | 100.0 | 98.5 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 105841 | 106833 | + | fepG | 100.0 | 99.2 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00016 | 113090 | 114292 | - | fes | 100.0 | 99.2 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00002 | 14738 | 15343 | + | fimA | 100.0 | 97.5 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 12638 | 13240 | + | fimB | 100.0 | 100.0 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 15984 | 16709 | + | fimC | 100.0 | 99.2 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 16775 | 19411 | + | fimD | 100.0 | 99.0 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 13718 | 14314 | + | fimE | 100.0 | 99.8 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 19418 | 19951 | + | fimF | 100.0 | 99.1 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 19964 | 20467 | + | fimG | 100.0 | 98.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 20478 | 21389 | + | fimH | 100.0 | 99.6 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 15408 | 15947 | + | fimI | 100.0 | 99.4 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00028 | 45687 | 46382 | - | focC | 100.0 | 99.6 | NP_753155 | (focC) F1C periplasmic chaperone [F1C fimbriae (VF0224)] [Escherichia coli CFT073] |
| contig00028 | 42987 | 45665 | - | focD | 100.0 | 99.8 | NP_753156 | (focD) F1C fimbrial usher [F1C fimbriae (VF0224)] [Escherichia coli CFT073] |
| contig00028 | 41922 | 42425 | - | focG | 100.0 | 100.0 | NP_753158 | (focG) F1C minor fimbrial subunit protein G presursor [F1C fimbriae (VF0224)] [Escherichia coli CFT073] |
| contig00028 | 40961 | 41971 | - | focH | 100.0 | 99.0 | NP_753159 | (focH) F1C Putative fimbrial adhesin precursor [F1C fimbriae (VF0224)] [Escherichia coli CFT073] |
| contig00011 | 29434 | 31455 | - | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00003 | 122250 | 123080 | - | gspC | 100.0 | 94.0 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 120160 | 122010 | - | gspD | 100.0 | 94.4 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 118667 | 120160 | - | gspE | 100.0 | 93.4 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 117468 | 118667 | - | gspF | 100.0 | 93.6 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 116972 | 117427 | - | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 116405 | 116935 | - | gspH | 100.0 | 92.8 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 116037 | 116408 | - | gspI | 100.0 | 93.3 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 115435 | 116004 | - | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 114461 | 115438 | - | gspK | 100.0 | 96.1 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 113286 | 114146 | - | gspL | 100.0 | 94.9 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00003 | 112749 | 113170 | - | gspM | 99.8 | 93.1 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00042 | 1 | 3054 | + | hlyA | 99.3 | 99.2 | NP_755445 | (hlyA) Hemolysin A [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00042 | 3125 | 5248 | + | hlyB | 100.0 | 99.5 | NP_755448 | (hlyB) Hemolysin B [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00025 | 72150 | 72823 | + | hlyC | 99.8 | 99.0 | NP_755444 | (hlyC) Hemolysin C [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00042 | 5267 | 6703 | + | hlyD | 100.0 | 98.3 | NP_755449 | (hlyD) Hemolysin D [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00002 | 44055 | 45425 | + | ibeA | 99.9 | 98.6 | AAF98391 | (ibeA) invasion protein IbeA [Ibes (VF0237)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00041 | 1787 | 2949 | + | iroB | 99.9 | 98.4 | NP_753168 | (iroB) glucosyltransferase IroB [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00041 | 3012 | 6749 | + | iroC | 100.0 | 99.2 | NP_753167 | (iroC) ATP binding cassette transporter [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00041 | 6853 | 8082 | + | iroD | 100.0 | 98.9 | NP_753166 | (iroD) esterase [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00041 | 8167 | 9123 | + | iroE | 100.0 | 99.5 | NP_753165 | (iroE) esterase [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00041 | 9168 | 11345 | - | iroN | 100.0 | 99.1 | NP_753164 | (iroN) salmochelin receptor IroN [IroN (VF0230)] [Escherichia coli CFT073] |
| contig00011 | 35064 | 44555 | - | irp1 | 100.0 | 99.8 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 44643 | 50750 | - | irp2 | 100.0 | 98.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00003 | 97919 | 99595 | + | kpsD | 100.0 | 99.5 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00003 | 110913 | 111689 | - | kpsM | 100.0 | 99.9 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00003 | 110257 | 110916 | - | kpsT | 100.0 | 100.0 | AAA24047 | (kpsT) KpsT [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00006 | 175322 | 176362 | - | ompA | 100.0 | 99.5 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00003 | 10572 | 14081 | - | pic | 85.2 | 95.6 | YP_006098864 | (pic) Pic serine protease precursor autotransporter [Pic (VF0218)] [Escherichia coli O44:H18 042] |
| contig00028 | 47956 | 48285 | - | sfaB | 100.0 | 99.4 | YP_540123 | (sfaB) S fimbrial switch regulatory protein SfaB [S fimbriae (VF0222)] [Escherichia coli UTI89] |
| contig00028 | 48641 | 48925 | + | sfaC | 100.0 | 96.8 | YP_540122 | (sfaC) S fimbrial switch regulatory protein SfaC [S fimbriae (VF0222)] [Escherichia coli UTI89] |
| contig00028 | 46423 | 46971 | - | sfaD | 100.0 | 98.9 | YP_540125 | (sfaD) S fimbriae minor subunit SfaD [S fimbriae (VF0222)] [Escherichia coli UTI89] |
| contig00028 | 42447 | 42974 | - | sfaG | 100.0 | 100.0 | YP_540128 | (sfaG) S fimbriae minor subunit SfaG [S fimbriae (VF0222)] [Escherichia coli UTI89] |
| contig00028 | 39219 | 39770 | - | sfaX | 100.0 | 98.2 | YP_540132 | (sfaX) regulatory protein SfaX [S fimbriae (VF0222)] [Escherichia coli UTI89] |
| contig00028 | 39917 | 40657 | - | sfaY | 100.0 | 98.5 | YP_540131 | (sfaY) regulatory protein SfaY [S fimbriae (VF0222)] [Escherichia coli UTI89] |
| contig00011 | 74193 | 75116 | - | tcpC | 100.0 | 100.0 | NP_754290 | (tcpC) Tir domain containing protein TcpC [TcpC (VF0413)] [Escherichia coli CFT073] |
| contig00004 | 127965 | 132095 | - | vat | 100.0 | 100.0 | NP_752330 | (vat) Haemoglobin protease [Tsh (VF0233)] [Escherichia coli CFT073] |
| contig00004 | 135712 | 136465 | - | yagV/ecpE | 99.7 | 98.4 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 136389 | 138032 | - | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 138022 | 140547 | - | yagX/ecpC | 100.0 | 97.6 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 140573 | 141241 | - | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 141298 | 141885 | - | yagZ/ecpA | 100.0 | 98.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00011 | 50941 | 51900 | - | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 31586 | 33163 | - | ybtE | 100.0 | 99.9 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 52067 | 53869 | + | ybtP | 100.0 | 99.8 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 53856 | 55658 | + | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 56959 | 58263 | + | ybtS | 100.0 | 99.8 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 33167 | 33970 | - | ybtT | 100.0 | 99.8 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 33967 | 35067 | - | ybtU | 100.0 | 99.9 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 55651 | 56931 | + | ybtX | 100.0 | 99.7 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00004 | 141959 | 142549 | - | ykgK/ecpR | 100.0 | 99.3 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00032 | 55910 | 56215 | - | afaA | 100.0 | 100.0 | CAW30797 | (afaA) fimbrial major subunit AfaA [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00032 | 54868 | 55612 | - | afaB-I | 100.0 | 99.6 | CAW30798 | (afaB-I) chaperone AfaB [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00032 | 52193 | 54775 | - | afaC-I | 100.0 | 99.9 | CAW30799 | (afaC-I) usher AfaC [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00032 | 51734 | 52177 | - | afaD | 100.0 | 100.0 | CAW30800 | (afaD) AfaD [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00032 | 50496 | 50981 | - | afaE-I | 100.0 | 99.8 | CAW30801 | (afaE-I) AFA-I adhesin [Afa/Dr family (VF0212)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00022 | 71077 | 72505 | + | aslA | 100.0 | 98.2 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 172126 | 174072 | - | chuA | 100.0 | 99.5 | NP_756170 | (chuA) Outer membrane heme/hemoglobin receptor ChuA [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 171049 | 172077 | - | chuS | 100.0 | 99.0 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 174714 | 175706 | + | chuT | 100.0 | 99.8 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 178242 | 179234 | + | chuU | 100.0 | 99.5 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 179201 | 180001 | + | chuV | 100.0 | 99.8 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 175726 | 177063 | + | chuW | 100.0 | 98.9 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 177076 | 177570 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00008 | 177570 | 178193 | + | chuY | 100.0 | 98.2 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00011 | 103007 | 103462 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00011 | 104215 | 104865 | + | csgD | 100.0 | 81.6 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00011 | 105284 | 105700 | + | csgF | 99.0 | 80.8 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00011 | 105727 | 106560 | + | csgG | 100.0 | 83.2 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 57133 | 57360 | + | daaF | 100.0 | 100.0 | AAA23662 | (daaF) DaaF protein [F1845 fimbrial adhesin (AI016)] [Escherichia coli str. C1845] |
| contig00032 | 51183 | 51356 | - | draP | 100.0 | 98.8 | AAK16479 | (draP) DraP [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00006 | 150253 | 150999 | - | entA | 100.0 | 98.1 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 150999 | 151856 | - | entB | 100.0 | 99.4 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 153490 | 154677 | - | entC | 100.0 | 98.7 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 169166 | 169827 | + | entD | 85.9 | 96.7 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 151870 | 153480 | - | entE | 100.0 | 98.9 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 161357 | 165238 | - | entF | 100.0 | 98.2 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 155814 | 157064 | - | entS | 100.0 | 97.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00001 | 228836 | 233083 | - | fdeC | 99.9 | 97.4 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00006 | 166901 | 169141 | + | fepA | 100.0 | 98.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 154854 | 155810 | + | fepB | 100.0 | 98.4 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 159165 | 159980 | + | fepC | 100.0 | 99.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 157163 | 158179 | + | fepD | 100.0 | 97.8 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 158176 | 159168 | + | fepG | 100.0 | 97.9 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 165456 | 166658 | - | fes | 100.0 | 99.0 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00031 | 63484 | 64088 | - | fimA | 99.8 | 90.8 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 62118 | 62843 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 59415 | 62051 | - | fimD | 100.0 | 98.5 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00054 | 8989 | 9585 | + | fimE | 100.0 | 98.8 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 58875 | 59408 | - | fimF | 100.0 | 96.6 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 58359 | 58862 | - | fimG | 100.0 | 98.2 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 57437 | 58348 | - | fimH | 100.0 | 97.5 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 62880 | 63419 | - | fimI | 100.0 | 98.5 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00024 | 51772 | 53793 | - | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00007 | 167409 | 168239 | + | gspC | 100.0 | 93.9 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 168479 | 170329 | + | gspD | 100.0 | 96.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 170329 | 171822 | + | gspE | 100.0 | 95.0 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 171822 | 173021 | + | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 173062 | 173517 | + | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 173554 | 174084 | + | gspH | 100.0 | 94.7 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 174081 | 174452 | + | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 174485 | 175054 | + | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 175051 | 176028 | + | gspK | 100.0 | 96.6 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 176343 | 177203 | + | gspL | 100.0 | 94.8 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00007 | 177319 | 177740 | + | gspM | 99.8 | 92.9 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00024 | 57402 | 66893 | - | irp1 | 100.0 | 99.8 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 66981 | 73088 | - | irp2 | 100.0 | 99.4 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00039 | 9495 | 11276 | + | iucA | 100.0 | 99.8 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00039 | 11277 | 12224 | + | iucB | 100.0 | 99.8 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00039 | 12224 | 13966 | + | iucC | 100.0 | 98.2 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00039 | 13963 | 15284 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00039 | 15222 | 17523 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00007 | 192461 | 194137 | - | kpsD | 100.0 | 98.3 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00007 | 178799 | 179575 | + | kpsM | 100.0 | 94.7 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00035 | 37571 | 38623 | - | ompA | 100.0 | 95.8 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00039 | 1409 | 1722 | - | papB | 99.7 | 98.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig00039 | 2127 | 2360 | + | papI | 100.0 | 94.9 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00080 | 256 | 807 | + | papX | 100.0 | 97.6 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00039 | 18455 | 22354 | + | sat | 100.0 | 99.6 | NP_755494 | (sat) Aecreted auto transpoter toxin [Sat (VF0231)] [Escherichia coli CFT073] |
| contig00001 | 248421 | 249174 | + | yagV/ecpE | 99.7 | 98.0 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 246854 | 248497 | + | yagW/ecpD | 100.0 | 99.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 244339 | 246864 | + | yagX/ecpC | 100.0 | 97.6 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 243645 | 244313 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 243001 | 243588 | + | yagZ/ecpA | 100.0 | 98.5 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 73279 | 74238 | - | ybtA | 100.0 | 99.3 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 53924 | 55501 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 74405 | 76207 | + | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 76194 | 77996 | + | ybtQ | 100.0 | 99.6 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 79297 | 80601 | + | ybtS | 100.0 | 99.8 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 55505 | 56308 | - | ybtT | 100.0 | 99.6 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 56305 | 57405 | - | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 77989 | 79269 | + | ybtX | 100.0 | 99.7 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 242336 | 242926 | + | ykgK/ecpR | 100.0 | 99.5 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00032 | 16542 | 17970 | + | aslA | 100.0 | 92.9 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00049 | 35888 | 36343 | - | csgB | 99.8 | 83.4 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 127197 | 127847 | - | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 126362 | 126778 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 125502 | 126335 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00038 | 27334 | 28080 | - | entA | 100.0 | 96.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 28080 | 28937 | - | entB | 100.0 | 98.4 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 30571 | 31758 | - | entC | 100.0 | 98.3 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 46402 | 47172 | + | entD | 100.0 | 95.1 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 28951 | 30561 | - | entE | 100.0 | 95.8 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 38621 | 42474 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 33081 | 34331 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00001 | 78504 | 80404 | - | espL1 | 100.0 | 97.4 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00046 | 14116 | 15170 | - | espR1 | 83.7 | 93.9 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 64048 | 65468 | + | espX1 | 99.9 | 95.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 37035 | 38615 | + | espX4 | 99.9 | 94.0 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 68120 | 69412 | - | espX5 | 100.0 | 97.0 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00022 | 24999 | 25780 | - | espY1 | 99.9 | 90.4 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00081 | 2689 | 6937 | + | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00038 | 44137 | 46377 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 32121 | 33077 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 36432 | 37247 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 34430 | 35446 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 35443 | 36435 | + | fepG | 100.0 | 94.0 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 42692 | 43894 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00051 | 2396 | 3007 | - | fimA | 100.0 | 88.1 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 4504 | 5106 | - | fimB | 100.0 | 97.0 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 1030 | 1755 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 3430 | 4026 | - | fimE | 100.0 | 99.5 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00056 | 28791 | 29324 | - | fimF | 100.0 | 99.1 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00056 | 28275 | 28778 | - | fimG | 100.0 | 98.2 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00056 | 27353 | 28264 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 1792 | 2331 | - | fimI | 100.0 | 99.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00006 | 54589 | 55629 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00035 | 6157 | 6910 | + | yagV/ecpE | 99.7 | 97.0 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 4590 | 6233 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 2076 | 4600 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 1382 | 2050 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 737 | 1324 | + | yagZ/ecpA | 100.0 | 99.0 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00035 | 72 | 662 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00022 | 49173 | 50601 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00034 | 8088 | 8543 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00034 | 6681 | 7331 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00034 | 5846 | 6262 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00034 | 4986 | 5819 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00040 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00027 | 14871 | 16771 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 7232 | 9418 | - | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00041 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 58678 | 60099 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 37634 | 39214 | + | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 68713 | 70005 | - | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 98245 | 99056 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 33554 | 37802 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00040 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00040 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00051 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00051 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00033 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00006 | 103766 | 104806 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00025 | 46912 | 47665 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 45345 | 46988 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 42830 | 45355 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 42136 | 42804 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 41491 | 42078 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00033 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00033 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00025 | 40826 | 41416 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00020 | 49173 | 50601 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00033 | 8088 | 8543 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00033 | 6681 | 7331 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00033 | 5846 | 6262 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00033 | 4986 | 5819 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00044 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00023 | 23930 | 25830 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 57649 | 59835 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00046 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 50505 | 51926 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 27853 | 29433 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00037 | 1604 | 2896 | - | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00002 | 90072 | 90883 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 204873 | 209121 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00044 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00044 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00053 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00038 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00005 | 103766 | 104806 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 218232 | 218985 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 216665 | 218308 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 214150 | 216675 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 213456 | 214124 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 212811 | 213398 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00038 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00038 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 212146 | 212736 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00111 | 327 | 1159 | + | csgG | 99.9 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00014 | 58920 | 59666 | - | entA | 100.0 | 96.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 59666 | 60523 | - | entB | 100.0 | 97.9 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 62157 | 63344 | - | entC | 100.0 | 97.6 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 77802 | 78572 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 60537 | 62147 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 70021 | 73874 | - | entF | 99.3 | 95.5 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 64481 | 65731 | - | entS | 100.0 | 95.7 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00062 | 10888 | 12787 | + | espL1 | 100.0 | 97.6 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00097 | 8110 | 9165 | + | espR1 | 83.8 | 94.3 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 62447 | 63790 | + | espX1 | 94.5 | 95.3 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00014 | 75537 | 77777 | + | fepA | 100.0 | 97.2 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 63521 | 64477 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 67832 | 68647 | + | fepC | 100.0 | 96.6 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 65830 | 66846 | + | fepD | 100.0 | 95.5 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 66843 | 67835 | + | fepG | 100.0 | 94.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00014 | 74092 | 75294 | - | fes | 100.0 | 96.6 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00071 | 20418 | 20951 | - | fimF | 100.0 | 97.6 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00071 | 19902 | 20405 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00071 | 18980 | 19891 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00030 | 419 | 1249 | + | gspC | 100.0 | 95.2 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 1489 | 3339 | + | gspD | 100.0 | 97.8 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 3339 | 4832 | + | gspE | 100.0 | 96.8 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 4832 | 6031 | + | gspF | 100.0 | 95.9 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 6072 | 6527 | + | gspG | 100.0 | 95.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 6564 | 7094 | + | gspH | 100.0 | 94.9 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 7091 | 7462 | + | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 7495 | 8064 | + | gspJ | 100.0 | 96.8 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 8061 | 9038 | + | gspK | 100.0 | 96.0 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 9353 | 10213 | + | gspL | 100.0 | 97.1 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00030 | 10329 | 10751 | + | gspM | 100.0 | 98.1 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 103916 | 104956 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00021 | 5141 | 5446 | + | afaA | 100.0 | 100.0 | CAW30797 | (afaA) fimbrial major subunit AfaA [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00021 | 5744 | 6488 | + | afaB-I | 100.0 | 99.7 | CAW30798 | (afaB-I) chaperone AfaB [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00021 | 6581 | 9163 | + | afaC-I | 100.0 | 99.8 | CAW30799 | (afaC-I) usher AfaC [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00021 | 10369 | 10851 | + | afaE-V | 100.0 | 83.8 | CAA62863 | (afaE-V) AfaE-V adhesin [Afimbrial adhesin AFA-V (AI013)] [Escherichia coli str. AL 851] |
| contig00019 | 52979 | 54407 | + | aslA | 100.0 | 97.1 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00028 | 36589 | 37617 | - | chuS | 100.0 | 96.4 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 43781 | 44773 | + | chuU | 100.0 | 96.6 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 44740 | 45540 | + | chuV | 100.0 | 98.2 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 41265 | 42602 | + | chuW | 100.0 | 96.8 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 43109 | 43732 | + | chuY | 100.0 | 96.5 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00016 | 13752 | 14207 | - | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00016 | 14962 | 15612 | + | csgD | 100.0 | 81.4 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00016 | 16031 | 16447 | + | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00016 | 16474 | 17307 | + | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 3996 | 4223 | - | daaF | 100.0 | 100.0 | AAA23662 | (daaF) DaaF protein [F1845 fimbrial adhesin (AI016)] [Escherichia coli str. C1845] |
| contig00021 | 9179 | 9622 | + | draD | 100.0 | 99.8 | AAK16478 | (draD) DraD periplasmic protein [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00021 | 9994 | 10167 | + | draP | 100.0 | 98.8 | AAK16479 | (draP) DraP [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00011 | 87837 | 88583 | - | entA | 100.0 | 97.3 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 88583 | 89440 | - | entB | 100.0 | 98.8 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 91074 | 92261 | - | entC | 100.0 | 97.3 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 106719 | 107489 | + | entD | 100.0 | 92.7 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 89454 | 91064 | - | entE | 100.0 | 96.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 98938 | 102791 | - | entF | 99.3 | 95.5 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 93398 | 94648 | - | entS | 100.0 | 95.7 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00001 | 112360 | 114258 | - | espL1 | 100.0 | 96.4 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00037 | 38824 | 41010 | + | espL4 | 100.0 | 97.4 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00050 | 8773 | 10025 | + | espR1 | 99.4 | 94.3 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 104206 | 105341 | - | espR4 | 99.6 | 84.5 | NP_288396 | (espR4) Type III secretion system effector espR4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 201678 | 203099 | + | espX1 | 100.0 | 96.0 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00037 | 4962 | 6542 | - | espX4 | 100.0 | 95.9 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00004 | 36414 | 37706 | - | espX5 | 100.0 | 95.9 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 162243 | 162991 | - | espY1 | 99.5 | 95.8 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 145208 | 145777 | - | espY2 | 100.0 | 94.6 | NP_285765 | (espY2) Type III secretion system effector EspY2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00044 | 31222 | 32793 | + | espY3 | 100.0 | 95.4 | NP_286160 | (espY3) Type III secretion system effector EspY3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 39565 | 41973 | + | espY4 | 100.0 | 96.4 | NP_290352 | (espY4) Type III secretion system effector EspY4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 106400 | 110650 | - | fdeC | 100.0 | 95.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00011 | 104454 | 106694 | + | fepA | 100.0 | 96.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 92438 | 93394 | + | fepB | 100.0 | 97.7 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 96749 | 97564 | + | fepC | 100.0 | 96.9 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 94747 | 95763 | + | fepD | 100.0 | 96.0 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 95760 | 96752 | + | fepG | 100.0 | 94.2 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00011 | 103009 | 104211 | - | fes | 100.0 | 96.6 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00035 | 21384 | 21989 | - | fimA | 100.0 | 92.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 23487 | 24089 | - | fimB | 100.0 | 99.5 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 20018 | 20743 | - | fimC | 100.0 | 99.2 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 17316 | 19952 | - | fimD | 100.0 | 99.0 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 22413 | 23009 | - | fimE | 100.0 | 99.5 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 16776 | 17309 | - | fimF | 100.0 | 99.1 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 16260 | 16763 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 15338 | 16249 | - | fimH | 100.0 | 98.9 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 20780 | 21319 | - | fimI | 100.0 | 99.4 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 33458 | 35479 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 217159 | 217989 | + | gspC | 100.0 | 95.2 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 218229 | 220079 | + | gspD | 100.0 | 96.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 220079 | 221572 | + | gspE | 100.0 | 95.0 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 221572 | 222771 | + | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 222812 | 223267 | + | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 223304 | 223834 | + | gspH | 100.0 | 94.7 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 223831 | 224202 | + | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 224235 | 224804 | + | gspJ | 100.0 | 94.4 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 224801 | 225778 | + | gspK | 100.0 | 96.6 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 226093 | 226953 | + | gspL | 100.0 | 94.8 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 227069 | 227490 | + | gspM | 99.8 | 92.7 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00031 | 20358 | 29849 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 14163 | 20270 | + | irp2 | 100.0 | 99.7 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 242211 | 243887 | - | kpsD | 100.0 | 98.3 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00002 | 228549 | 229325 | + | kpsM | 100.0 | 94.8 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00016 | 85780 | 86832 | + | ompA | 100.0 | 95.2 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00006 | 157140 | 157691 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00028 | 37666 | 39648 | - | shuA | 100.0 | 98.5 | YP_405019 | (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00028 | 40253 | 41245 | + | shuT | 100.0 | 98.1 | YP_405017 | (shuT) periplasmic binding protein ShuT [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00028 | 42615 | 43109 | + | shuX | 100.0 | 96.4 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00007 | 125982 | 126735 | + | yagV/ecpE | 99.7 | 96.8 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 124415 | 126058 | + | yagW/ecpD | 100.0 | 99.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 121900 | 124425 | + | yagX/ecpC | 100.0 | 98.0 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 121206 | 121874 | + | yagY/ecpB | 100.0 | 98.4 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 120562 | 121149 | + | yagZ/ecpA | 100.0 | 99.0 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00031 | 13013 | 13972 | + | ybtA | 100.0 | 99.2 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 31750 | 33327 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 11044 | 12846 | - | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 9255 | 11057 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 6650 | 7954 | - | ybtS | 100.0 | 99.7 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 30943 | 31746 | + | ybtT | 100.0 | 99.5 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 29846 | 30946 | + | ybtU | 100.0 | 99.1 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 7982 | 9262 | - | ybtX | 100.0 | 99.4 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00007 | 119897 | 120487 | + | ykgK/ecpR | 100.0 | 99.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00058 | 8036 | 8152 | + | astA | 100.0 | 99.1 | BAA94855 | (astA) heat-stable enterotoxin 1 [EAST1 (VF0216)] [Escherichia coli O44:H18 042] |
| contig00014 | 136791 | 137246 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00014 | 138000 | 138650 | + | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00014 | 139069 | 139485 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00014 | 139512 | 140345 | + | csgG | 100.0 | 83.1 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00058 | 12954 | 13730 | + | eltA | 100.0 | 99.5 | AAA24685 | (eltA) heat-labile enterotoxin A prepeptide (from human) [Heat-labile toxin (LT) (VF0210)] [Escherichia coli] |
| contig00058 | 13727 | 14101 | + | eltB | 100.0 | 99.2 | AAA98064 | (eltB) enterotoxin subunit B (from human) [Heat-labile toxin (LT) (VF0210)] [Escherichia coli] |
| contig00015 | 99312 | 100058 | - | entA | 100.0 | 95.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 100058 | 100915 | - | entB | 100.0 | 97.8 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 102549 | 103736 | - | entC | 100.0 | 97.6 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 118381 | 119151 | + | entD | 100.0 | 94.0 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 100929 | 102539 | - | entE | 100.0 | 96.0 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 110624 | 114453 | - | entF | 98.7 | 95.9 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 105059 | 106309 | - | entS | 100.0 | 95.6 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00019 | 56923 | 58791 | + | espL1 | 98.4 | 95.2 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 11959 | 13014 | - | espR1 | 83.8 | 94.2 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 39315 | 40735 | + | espX1 | 99.9 | 95.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 242755 | 244335 | - | espX4 | 99.9 | 92.9 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 211962 | 213254 | + | espX5 | 100.0 | 95.6 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 27502 | 31727 | - | fdeC | 99.4 | 91.1 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00015 | 116116 | 118356 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 104099 | 105055 | + | fepB | 100.0 | 97.4 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 108410 | 109225 | + | fepC | 100.0 | 97.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 106408 | 107424 | + | fepD | 100.0 | 95.6 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 107421 | 108413 | + | fepG | 100.0 | 94.7 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 114671 | 115873 | - | fes | 100.0 | 96.5 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00010 | 156459 | 157063 | - | fimA | 99.8 | 90.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00066 | 1111 | 1713 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00010 | 155093 | 155818 | - | fimC | 100.0 | 98.3 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00010 | 152390 | 155026 | - | fimD | 100.0 | 98.7 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00066 | 37 | 633 | - | fimE | 100.0 | 99.2 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00010 | 151850 | 152383 | - | fimF | 100.0 | 97.8 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00010 | 151334 | 151837 | - | fimG | 100.0 | 98.4 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00010 | 150412 | 151323 | - | fimH | 100.0 | 97.7 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00010 | 155855 | 156394 | - | fimI | 100.0 | 99.1 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00013 | 29070 | 29900 | - | gspC | 100.0 | 94.6 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 26980 | 28830 | - | gspD | 100.0 | 97.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 25487 | 26980 | - | gspE | 100.0 | 96.0 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 24288 | 25487 | - | gspF | 100.0 | 96.3 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 23792 | 24247 | - | gspG | 100.0 | 96.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 23225 | 23755 | - | gspH | 100.0 | 95.5 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 22857 | 23228 | - | gspI | 100.0 | 94.6 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 22255 | 22824 | - | gspJ | 100.0 | 97.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 21281 | 22258 | - | gspK | 100.0 | 97.3 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 20106 | 20966 | - | gspL | 100.0 | 97.3 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00013 | 19568 | 19990 | - | gspM | 100.0 | 97.2 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 139311 | 140351 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00021 | 40833 | 41586 | + | yagV/ecpE | 99.7 | 96.8 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 39266 | 40909 | + | yagW/ecpD | 100.0 | 98.6 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 36751 | 39276 | + | yagX/ecpC | 100.0 | 98.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 36057 | 36725 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 35412 | 35999 | + | yagZ/ecpA | 100.0 | 99.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 34747 | 35337 | + | ykgK/ecpR | 100.0 | 97.6 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00019 | 53204 | 54632 | + | aslA | 100.0 | 96.9 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00012 | 74057 | 75085 | + | chuS | 100.0 | 97.0 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00012 | 66900 | 67892 | - | chuU | 100.0 | 98.8 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00012 | 66133 | 66933 | - | chuV | 100.0 | 98.2 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00012 | 69071 | 70408 | - | chuW | 100.0 | 97.0 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00012 | 67941 | 68564 | - | chuY | 100.0 | 96.6 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00021 | 49597 | 50052 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 50796 | 51446 | + | csgD | 100.0 | 81.4 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 51865 | 52281 | + | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00021 | 52308 | 53141 | + | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00006 | 65922 | 66668 | - | entA | 100.0 | 96.1 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 66668 | 67525 | - | entB | 100.0 | 98.5 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 69159 | 70346 | - | entC | 100.0 | 97.5 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 84804 | 85574 | + | entD | 100.0 | 92.7 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 67539 | 69149 | - | entE | 100.0 | 96.0 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 77023 | 80876 | - | entF | 99.3 | 95.5 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 71483 | 72733 | - | entS | 100.0 | 95.6 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00002 | 226033 | 227931 | - | espL1 | 100.0 | 96.6 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00061 | 6908 | 9094 | + | espL4 | 100.0 | 96.5 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00034 | 45165 | 46586 | + | espX1 | 100.0 | 94.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00011 | 25482 | 27062 | + | espX4 | 100.0 | 96.1 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00011 | 56552 | 57844 | - | espX5 | 100.0 | 96.3 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00034 | 5345 | 6093 | - | espY1 | 99.5 | 95.6 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 145005 | 145574 | - | espY2 | 100.0 | 94.7 | NP_285765 | (espY2) Type III secretion system effector EspY2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00025 | 8357 | 9928 | - | espY3 | 100.0 | 95.7 | NP_286160 | (espY3) Type III secretion system effector EspY3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 70981 | 73389 | - | espY4 | 100.0 | 95.9 | NP_290352 | (espY4) Type III secretion system effector EspY4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 96395 | 100645 | - | fdeC | 100.0 | 95.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00006 | 82539 | 84779 | + | fepA | 100.0 | 96.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 70523 | 71479 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 74834 | 75649 | + | fepC | 100.0 | 96.7 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 72832 | 73848 | + | fepD | 100.0 | 95.9 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 73845 | 74837 | + | fepG | 100.0 | 93.8 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00006 | 81094 | 82296 | - | fes | 100.0 | 96.4 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00023 | 46260 | 46865 | - | fimA | 100.0 | 92.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 48363 | 48965 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 44894 | 45619 | - | fimC | 100.0 | 98.5 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 42191 | 44827 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 47289 | 47885 | - | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 41651 | 42184 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 41135 | 41638 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 40213 | 41124 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00023 | 45656 | 46195 | - | fimI | 100.0 | 98.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00026 | 35971 | 37992 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00008 | 17255 | 18085 | - | gspC | 100.0 | 95.3 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 15165 | 17015 | - | gspD | 100.0 | 96.3 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 13672 | 15165 | - | gspE | 100.0 | 94.8 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 12473 | 13672 | - | gspF | 100.0 | 94.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 11977 | 12432 | - | gspG | 100.0 | 96.3 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 11410 | 11940 | - | gspH | 100.0 | 96.4 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 11042 | 11413 | - | gspI | 100.0 | 94.4 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 10440 | 11009 | - | gspJ | 100.0 | 96.0 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 9466 | 10443 | - | gspK | 100.0 | 96.9 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 8291 | 9151 | - | gspL | 100.0 | 93.6 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00008 | 7754 | 8175 | - | gspM | 99.8 | 94.3 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00026 | 22871 | 32362 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 16676 | 22783 | + | irp2 | 100.0 | 99.7 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00062 | 2017 | 3798 | + | iucA | 100.0 | 99.8 | NP_709454 | (iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00062 | 3799 | 4746 | + | iucB | 100.0 | 99.8 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00062 | 4746 | 6488 | + | iucC | 100.0 | 98.2 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00062 | 6485 | 7806 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00062 | 7744 | 10045 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00059 | 11086 | 12762 | - | kpsD | 100.0 | 99.5 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00008 | 5920 | 6696 | - | kpsM | 100.0 | 94.8 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00010 | 102451 | 103503 | - | ompA | 100.0 | 95.2 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00083 | 749 | 1062 | - | papB | 99.7 | 98.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig00083 | 1467 | 1700 | + | papI | 100.0 | 94.9 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00121 | 366 | 917 | + | papX | 100.0 | 97.6 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00062 | 10977 | 14876 | + | sat | 100.0 | 99.6 | NP_755494 | (sat) Aecreted auto transpoter toxin [Sat (VF0231)] [Escherichia coli CFT073] |
| contig00072 | 8392 | 9530 | + | senB | 99.9 | 99.7 | YP_406304 | (senB) enterotoxin [ShET2 (VF0258)] [Shigella flexneri 2a str. 301] |
| contig00012 | 72026 | 74008 | + | shuA | 100.0 | 98.7 | YP_405019 | (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00012 | 70428 | 71420 | - | shuT | 100.0 | 97.9 | YP_405017 | (shuT) periplasmic binding protein ShuT [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00012 | 68564 | 69058 | - | shuX | 100.0 | 96.0 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00030 | 9764 | 10517 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00030 | 8197 | 9840 | + | yagW/ecpD | 100.0 | 98.8 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00030 | 5682 | 8207 | + | yagX/ecpC | 100.0 | 98.1 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00030 | 4988 | 5656 | + | yagY/ecpB | 100.0 | 97.9 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00030 | 4343 | 4930 | + | yagZ/ecpA | 100.0 | 99.0 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 15526 | 16485 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 34263 | 35840 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 13557 | 15359 | - | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 11768 | 13570 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 9163 | 10467 | - | ybtS | 100.0 | 99.7 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 33456 | 34259 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 32359 | 33459 | + | ybtU | 100.0 | 99.9 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00026 | 10495 | 11775 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00030 | 3678 | 4268 | + | ykgK/ecpR | 100.0 | 99.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00020 | 49279 | 50707 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00032 | 40481 | 40936 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 41691 | 42341 | + | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 42760 | 43176 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 43203 | 44036 | + | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00013 | 99075 | 99821 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 99821 | 100678 | - | entB | 100.0 | 98.0 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 102312 | 103499 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 118143 | 118913 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 100692 | 102302 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 110362 | 114215 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 104822 | 106072 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00054 | 7845 | 9743 | + | espL1 | 100.0 | 97.6 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00048 | 19357 | 21543 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00042 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 48325 | 49460 | - | espR4 | 99.6 | 84.4 | NP_288396 | (espR4) Type III secretion system effector espR4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00008 | 144229 | 145650 | + | espX1 | 100.0 | 95.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 164232 | 165812 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 133441 | 134733 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00008 | 105275 | 106086 | - | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 206256 | 210504 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00013 | 115878 | 118118 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 103862 | 104818 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 108173 | 108988 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 106171 | 107187 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 107184 | 108176 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 114433 | 115635 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00027 | 32354 | 34375 | - | fyuA | 100.0 | 100.0 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 37984 | 47475 | - | irp1 | 100.0 | 99.8 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 47563 | 53670 | - | irp2 | 100.0 | 99.8 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00058 | 7015 | 8802 | + | iucA | 100.0 | 94.2 | NP_755502 | (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00058 | 8803 | 9750 | + | iucB | 100.0 | 95.6 | NP_755501 | (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00058 | 9750 | 11492 | + | iucC | 100.0 | 96.0 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00058 | 11489 | 12810 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00058 | 12748 | 15049 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00004 | 139036 | 140076 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 219611 | 220364 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 218044 | 219687 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 215529 | 218054 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 214835 | 215503 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 214190 | 214777 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00027 | 53861 | 54820 | - | ybtA | 100.0 | 99.9 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 34506 | 36083 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 54987 | 56789 | + | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 56776 | 58578 | + | ybtQ | 100.0 | 99.8 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 59879 | 61183 | + | ybtS | 100.0 | 97.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 36087 | 36890 | - | ybtT | 100.0 | 99.8 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 36887 | 37987 | - | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00027 | 58571 | 59851 | + | ybtX | 100.0 | 97.7 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 213525 | 214115 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00034 | 2949 | 3254 | - | afaA | 100.0 | 100.0 | CAW30797 | (afaA) fimbrial major subunit AfaA [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00034 | 1886 | 2630 | - | afaB-I | 100.0 | 99.6 | CAW30798 | (afaB-I) chaperone AfaB [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00158 | 3718 | 4161 | - | afaD | 100.0 | 100.0 | CAW30800 | (afaD) AfaD [Afimbrial adhesin AFA-I mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] |
| contig00158 | 2480 | 2965 | - | afaE-I | 100.0 | 99.8 | CAW30801 | (afaE-I) AFA-I adhesin [Afa/Dr family (VF0212)] [Escherichia coli O25b:H4 str. FV9863] |
| contig02639 | 303 | 797 | + | chuX | 100.0 | 100.0 | NP_756177 | (chuX) putative heme-binding protein ChuX [Chu (VF0227)] [Escherichia coli CFT073] |
| contig02770 | 116 | 571 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig01231 | 899 | 1315 | + | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00034 | 4175 | 4402 | + | daaF | 100.0 | 100.0 | AAA23662 | (daaF) DaaF protein [F1845 fimbrial adhesin (AI016)] [Escherichia coli str. C1845] |
| contig00158 | 3167 | 3340 | - | draP | 100.0 | 98.8 | AAK16479 | (draP) DraP [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128] |
| contig00442 | 98 | 1285 | + | entC | 100.0 | 97.5 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00538 | 177 | 947 | + | entD | 100.0 | 94.3 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00748 | 1084 | 1854 | + | entD | 100.0 | 99.9 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00442 | 1295 | 2634 | + | entE | 83.2 | 98.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig01069 | 433 | 1545 | - | entS | 89.0 | 95.3 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00580 | 92 | 1990 | - | espL1 | 100.0 | 96.2 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00285 | 1971 | 3221 | + | espR1 | 99.3 | 94.6 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00169 | 2908 | 4047 | - | espR3 | 100.0 | 96.4 | NP_288394 | (espR3) Type III secretion system effector espR3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00365 | 973 | 2394 | + | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00641 | 168 | 1748 | + | espX4 | 100.0 | 94.9 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00804 | 637 | 1448 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00052 | 5564 | 7972 | + | espY4 | 99.8 | 89.4 | NP_290352 | (espY4) Type III secretion system effector EspY4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00127 | 2810 | 3625 | - | fepC | 100.0 | 97.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig03168 | 1 | 672 | + | fepC | 82.3 | 99.7 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00127 | 4611 | 5627 | - | fepD | 100.0 | 97.0 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00127 | 3622 | 4614 | - | fepG | 100.0 | 95.3 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00312 | 2572 | 3177 | - | fimA | 100.0 | 92.1 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00527 | 1076 | 1678 | + | fimB | 100.0 | 99.7 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00312 | 1206 | 1931 | - | fimC | 100.0 | 99.2 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00235 | 1766 | 2299 | - | fimF | 100.0 | 99.1 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00235 | 1250 | 1753 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00235 | 328 | 1239 | - | fimH | 100.0 | 99.0 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00312 | 1968 | 2507 | - | fimI | 100.0 | 99.4 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00138 | 37 | 1887 | + | gspD | 100.0 | 94.8 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00138 | 1887 | 3380 | + | gspE | 100.0 | 94.5 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00138 | 3380 | 4579 | + | gspF | 100.0 | 94.1 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00138 | 4620 | 5075 | + | gspG | 100.0 | 96.3 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig03850 | 233 | 550 | + | gspI | 85.5 | 95.0 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00462 | 1212 | 2189 | - | gspK | 100.0 | 97.2 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00462 | 37 | 897 | - | gspL | 100.0 | 95.0 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig01035 | 307 | 1167 | + | gspL | 100.0 | 94.7 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig01267 | 1 | 366 | + | gspM | 86.5 | 95.6 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00562 | 893 | 1255 | + | gtrA | 100.0 | 92.0 | NP_706257 | (gtrA) bactoprenol-linked glucose translocase/flippase [LPS (VF0124)] [Shigella flexneri 2a str. 301] |
| contig00562 | 1252 | 2158 | + | gtrB | 97.5 | 82.2 | NP_706258 | (gtrB) bactoprenol glucosyl transferase [LPS (VF0124)] [Shigella flexneri 2a str. 301] |
| contig00153 | 659 | 3733 | + | hlyA | 100.0 | 99.9 | NP_755445 | (hlyA) Hemolysin A [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00153 | 1 | 647 | + | hlyC | 95.8 | 100.0 | NP_755444 | (hlyC) Hemolysin C [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00451 | 901 | 2337 | + | hlyD | 100.0 | 99.9 | NP_755449 | (hlyD) Hemolysin D [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00167 | 1596 | 2825 | + | iroD | 100.0 | 99.4 | NP_753166 | (iroD) esterase [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00167 | 2910 | 3866 | + | iroE | 100.0 | 99.2 | NP_753165 | (iroE) esterase [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00260 | 300 | 1247 | + | iucB | 100.0 | 100.0 | NP_709455 | (iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00260 | 1247 | 2989 | + | iucC | 100.0 | 99.9 | NP_709456 | (iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123)] [Shigella flexneri 2a str. 301] |
| contig00219 | 627 | 2906 | + | iutA | 100.0 | 99.6 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00387 | 728 | 2404 | + | kpsD | 100.0 | 98.0 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00083 | 271 | 2793 | + | papC | 100.0 | 99.8 | NP_755465 | (papC) usher protein PapC [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00083 | 2993 | 3598 | + | papD | 100.0 | 99.8 | NP_755464 | (papD) chaperone protein PapD [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00083 | 5361 | 5891 | + | papF | 100.0 | 99.2 | NP_755459 | (papF) P pilus minor subunit PapF [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00083 | 5935 | 6945 | + | papG | 100.0 | 99.1 | NP_755458 | (papG) P pilus tip adhesin PapG [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00083 | 3635 | 4216 | + | papJ | 100.0 | 99.5 | NP_755463 | (papJ) P pilus assembly protein PapJ [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00083 | 4223 | 4762 | + | papK | 100.0 | 99.1 | NP_755461 | (papK) P pilus minor subunit PapK [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00090 | 6059 | 6610 | - | papX | 100.0 | 100.0 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00041 | 799 | 1937 | - | senB | 99.9 | 99.7 | YP_406304 | (senB) enterotoxin [ShET2 (VF0258)] [Shigella flexneri 2a str. 301] |
| contig01982 | 511 | 1005 | + | shuX | 100.0 | 96.2 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00082 | 1 | 3871 | + | vat | 93.7 | 99.7 | NP_752330 | (vat) Haemoglobin protease [Tsh (VF0233)] [Escherichia coli CFT073] |
| contig02336 | 340 | 884 | + | yagY/ecpB | 81.5 | 98.5 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig03003 | 177 | 721 | + | yagY/ecpB | 81.5 | 98.0 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00625 | 578 | 2140 | + | ybtQ | 86.7 | 99.9 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig01751 | 292 | 1095 | - | ybtT | 100.0 | 99.6 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00633 | 687 | 1967 | - | ybtX | 100.0 | 97.6 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00956 | 1 | 497 | - | ykgK/ecpR | 84.1 | 99.6 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00015 | 53014 | 54442 | + | aslA | 100.0 | 97.3 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00002 | 110304 | 111296 | - | chuU | 100.0 | 98.6 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00002 | 109537 | 110337 | - | chuV | 100.0 | 98.4 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00002 | 112475 | 113812 | - | chuW | 100.0 | 96.8 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00002 | 111345 | 111968 | - | chuY | 100.0 | 97.0 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00039 | 10912 | 11367 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00039 | 9507 | 10157 | - | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00039 | 8672 | 9088 | - | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00039 | 7812 | 8645 | - | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00009 | 84305 | 85051 | - | entA | 100.0 | 95.8 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 85051 | 85908 | - | entB | 100.0 | 97.2 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 87542 | 88729 | - | entC | 100.0 | 98.2 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 103186 | 103956 | + | entD | 100.0 | 93.8 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 85922 | 87532 | - | entE | 100.0 | 97.6 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 95405 | 99258 | - | entF | 99.3 | 95.9 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 89866 | 91116 | - | entS | 100.0 | 95.7 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00003 | 99918 | 101816 | - | espL1 | 100.0 | 96.4 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 7968 | 10154 | - | espL4 | 100.0 | 97.1 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00068 | 14349 | 15599 | - | espR1 | 99.3 | 94.2 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 120856 | 122277 | + | espX1 | 100.0 | 94.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00007 | 84366 | 86378 | - | espX2 | 100.0 | 96.7 | NP_286562 | (espX2) Type III secretion system effector EspX2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 42382 | 43962 | + | espX4 | 100.0 | 94.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00010 | 73473 | 74765 | - | espX5 | 100.0 | 95.6 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 81432 | 82151 | - | espY1 | 95.6 | 88.6 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 64452 | 65021 | - | espY2 | 100.0 | 94.2 | NP_285765 | (espY2) Type III secretion system effector EspY2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00006 | 120255 | 121826 | - | espY3 | 100.0 | 95.4 | NP_286160 | (espY3) Type III secretion system effector EspY3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 39417 | 41825 | + | espY4 | 100.0 | 92.7 | NP_290352 | (espY4) Type III secretion system effector EspY4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 3659 | 7900 | - | fdeC | 99.8 | 91.3 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00009 | 100921 | 103161 | + | fepA | 100.0 | 97.2 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 88906 | 89862 | + | fepB | 100.0 | 97.0 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 93217 | 94032 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 91215 | 92231 | + | fepD | 100.0 | 95.7 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 92228 | 93220 | + | fepG | 100.0 | 95.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 99476 | 100678 | - | fes | 100.0 | 97.4 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00001 | 38364 | 39194 | - | gspC | 100.0 | 95.4 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 36274 | 38124 | - | gspD | 100.0 | 95.6 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 34781 | 36274 | - | gspE | 100.0 | 95.3 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 33582 | 34781 | - | gspF | 100.0 | 91.5 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 33086 | 33541 | - | gspG | 100.0 | 97.4 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 32519 | 33049 | - | gspH | 100.0 | 96.2 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 32151 | 32522 | - | gspI | 100.0 | 94.9 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 31549 | 32118 | - | gspJ | 100.0 | 94.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 30575 | 31552 | - | gspK | 100.0 | 96.7 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 29400 | 30260 | - | gspL | 100.0 | 95.1 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 28863 | 29284 | - | gspM | 99.8 | 93.4 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00058 | 15698 | 16927 | + | iroD | 100.0 | 99.6 | NP_753166 | (iroD) esterase [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00058 | 17012 | 17969 | + | iroE | 100.0 | 99.0 | NP_753165 | (iroE) esterase [Salmochelin (IA013)] [Escherichia coli CFT073] |
| contig00001 | 14169 | 15845 | + | kpsD | 100.0 | 99.5 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 26913 | 27689 | - | kpsM | 100.0 | 94.1 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00012 | 26051 | 27103 | - | ompA | 100.0 | 95.2 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00135 | 961 | 1512 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00002 | 115430 | 117412 | + | shuA | 100.0 | 98.8 | YP_405019 | (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00002 | 117461 | 118489 | + | shuS | 100.0 | 96.8 | YP_405020 | (shuS) heme/hemoglobin transport protein ShuS [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00002 | 113832 | 114824 | - | shuT | 100.0 | 97.8 | YP_405017 | (shuT) periplasmic binding protein ShuT [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00002 | 111968 | 112462 | - | shuX | 100.0 | 96.6 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00040 | 23310 | 24063 | + | yagV/ecpE | 99.7 | 96.8 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 21743 | 23386 | + | yagW/ecpD | 100.0 | 98.2 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 19228 | 21753 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 18534 | 19202 | + | yagY/ecpB | 100.0 | 97.6 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 17889 | 18476 | + | yagZ/ecpA | 100.0 | 99.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 17225 | 17815 | + | ykgK/ecpR | 100.0 | 98.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00076 | 9106 | 9561 | - | csgB | 99.8 | 84.0 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00076 | 10315 | 10965 | + | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00076 | 11384 | 11800 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00076 | 11827 | 12660 | + | csgG | 100.0 | 83.1 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00028 | 35282 | 36028 | - | entA | 100.0 | 96.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 36028 | 36885 | - | entB | 100.0 | 97.9 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 38519 | 39706 | - | entC | 100.0 | 97.5 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 54350 | 55120 | + | entD | 100.0 | 94.0 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 36899 | 38509 | - | entE | 100.0 | 95.8 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 46593 | 50422 | - | entF | 98.7 | 95.4 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 41029 | 42279 | - | entS | 100.0 | 95.6 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00010 | 11533 | 13401 | - | espL1 | 98.4 | 95.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00047 | 24866 | 25921 | + | espR1 | 83.8 | 94.2 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00021 | 50824 | 52244 | + | espX1 | 99.9 | 94.7 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 55538 | 57118 | - | espX4 | 99.9 | 93.1 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 24726 | 26018 | + | espX5 | 100.0 | 95.7 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 43044 | 47285 | - | fdeC | 99.8 | 92.4 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00028 | 52085 | 54325 | + | fepA | 100.0 | 96.8 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 40069 | 41025 | + | fepB | 100.0 | 97.4 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 44380 | 45195 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 42378 | 43394 | + | fepD | 100.0 | 96.0 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 43391 | 44383 | + | fepG | 100.0 | 94.0 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00028 | 50640 | 51842 | - | fes | 100.0 | 96.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00014 | 97608 | 98213 | - | fimA | 100.0 | 92.2 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00054 | 1113 | 1715 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 96242 | 96967 | - | fimC | 100.0 | 98.5 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 93539 | 96175 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00054 | 39 | 635 | - | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 92999 | 93532 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 92483 | 92986 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 91561 | 92472 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00014 | 97004 | 97543 | - | fimI | 100.0 | 98.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00002 | 144864 | 145694 | - | gspC | 100.0 | 95.1 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 142774 | 144624 | - | gspD | 100.0 | 97.0 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 141281 | 142774 | - | gspE | 100.0 | 97.1 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 140082 | 141281 | - | gspF | 100.0 | 96.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 139586 | 140041 | - | gspG | 100.0 | 95.6 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 139019 | 139549 | - | gspH | 100.0 | 96.0 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 138651 | 139022 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 138049 | 138618 | - | gspJ | 100.0 | 97.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 137075 | 138052 | - | gspK | 100.0 | 96.1 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 135900 | 136760 | - | gspL | 100.0 | 97.6 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 135362 | 135784 | - | gspM | 100.0 | 94.1 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 104083 | 105135 | - | ompA | 100.0 | 94.3 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00012 | 56391 | 57144 | + | yagV/ecpE | 99.7 | 96.8 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 54824 | 56467 | + | yagW/ecpD | 100.0 | 98.6 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 52309 | 54834 | + | yagX/ecpC | 100.0 | 98.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 51615 | 52283 | + | yagY/ecpB | 100.0 | 98.7 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 50970 | 51557 | + | yagZ/ecpA | 100.0 | 99.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 50305 | 50895 | + | ykgK/ecpR | 100.0 | 97.6 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00028 | 619 | 2047 | + | aslA | 100.0 | 92.9 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00207 | 188 | 643 | - | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00207 | 1398 | 2048 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00207 | 2467 | 2883 | + | csgF | 99.0 | 81.0 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00207 | 2910 | 3743 | + | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00807 | 1 | 1533 | + | entE | 95.2 | 95.1 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig01126 | 1 | 1353 | + | entE | 84.0 | 94.9 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00258 | 371 | 1791 | + | espX1 | 99.9 | 95.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00671 | 360 | 1940 | - | espX4 | 100.0 | 96.5 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00134 | 2697 | 3989 | - | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00933 | 296 | 1118 | + | espY1 | 100.0 | 85.9 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00837 | 592 | 1548 | - | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00545 | 740 | 1756 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00156 | 4587 | 5192 | - | fimA | 100.0 | 95.5 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00005 | 23472 | 24074 | + | fimB | 100.0 | 97.7 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00156 | 3222 | 3947 | - | fimC | 100.0 | 99.2 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00156 | 519 | 3155 | - | fimD | 100.0 | 98.9 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00005 | 24552 | 25148 | + | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00156 | 1 | 512 | - | fimF | 95.9 | 99.0 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00446 | 1 | 509 | + | fimF | 95.3 | 97.5 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00446 | 522 | 1025 | + | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00446 | 1036 | 1947 | + | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00156 | 3984 | 4522 | - | fimI | 99.8 | 98.5 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00453 | 52 | 888 | + | fliG | 84.3 | 80.2 | YP_001006742 | (fliG) flagellar motor switch protein G [Flagella (VF0394)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
| contig00017 | 8334 | 10355 | + | fyuA | 100.0 | 99.7 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00004 | 17541 | 18371 | + | gspC | 100.0 | 95.4 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 18611 | 20461 | + | gspD | 100.0 | 97.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 20461 | 21954 | + | gspE | 100.0 | 96.5 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 21954 | 23153 | + | gspF | 100.0 | 96.1 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 23194 | 23649 | + | gspG | 100.0 | 95.0 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 23686 | 24216 | + | gspH | 100.0 | 95.3 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 24213 | 24584 | + | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 24617 | 25186 | + | gspJ | 100.0 | 96.7 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 25183 | 26160 | + | gspK | 100.0 | 96.7 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00004 | 26475 | 27335 | + | gspL | 100.0 | 97.1 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 9600 | 15713 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00060 | 2881 | 3921 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 8272 | 9025 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 6705 | 8348 | + | yagW/ecpD | 100.0 | 99.0 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 4190 | 6715 | + | yagX/ecpC | 100.0 | 98.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 3496 | 4164 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 2851 | 3438 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00006 | 8450 | 9409 | + | ybtA | 100.0 | 99.4 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00017 | 6626 | 8203 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00006 | 6481 | 8283 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00006 | 4692 | 6494 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00006 | 2087 | 3391 | - | ybtS | 100.0 | 99.8 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00017 | 5819 | 6622 | + | ybtT | 100.0 | 99.6 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00017 | 4722 | 5822 | + | ybtU | 100.0 | 99.2 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00006 | 3419 | 4699 | - | ybtX | 100.0 | 99.8 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 2186 | 2776 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00005 | 187988 | 188443 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00005 | 189197 | 189847 | + | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00005 | 190266 | 190682 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00005 | 190709 | 191542 | + | csgG | 100.0 | 83.0 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00013 | 99473 | 100219 | - | entA | 100.0 | 95.5 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 100219 | 101076 | - | entB | 100.0 | 97.4 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 102710 | 103897 | - | entC | 100.0 | 97.6 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 118541 | 119311 | + | entD | 100.0 | 94.3 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 101090 | 102700 | - | entE | 100.0 | 95.8 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 110784 | 114613 | - | entF | 98.7 | 95.4 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 105220 | 106470 | - | entS | 100.0 | 95.6 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00001 | 275319 | 277218 | - | espL1 | 100.0 | 95.7 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00033 | 24925 | 25980 | + | espR1 | 83.8 | 94.1 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 18826 | 20246 | + | espX1 | 99.9 | 95.8 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00009 | 60834 | 62414 | + | espX4 | 99.9 | 93.0 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00009 | 91971 | 93263 | - | espX5 | 100.0 | 95.9 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 38523 | 42771 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00013 | 116276 | 118516 | + | fepA | 100.0 | 97.1 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 104260 | 105216 | + | fepB | 100.0 | 97.1 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 108571 | 109386 | + | fepC | 100.0 | 97.2 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 106569 | 107585 | + | fepD | 100.0 | 96.0 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 107582 | 108574 | + | fepG | 100.0 | 94.0 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00013 | 114831 | 116033 | - | fes | 100.0 | 96.5 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00012 | 142063 | 142668 | - | fimA | 100.0 | 92.9 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 35938 | 36540 | + | fimB | 100.0 | 98.0 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00012 | 140697 | 141422 | - | fimC | 100.0 | 98.3 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00012 | 137994 | 140630 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00035 | 37018 | 37614 | + | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00012 | 137454 | 137987 | - | fimF | 100.0 | 98.3 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00012 | 136938 | 137441 | - | fimG | 100.0 | 98.2 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00012 | 136016 | 136927 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00012 | 141459 | 141998 | - | fimI | 100.0 | 99.1 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00001 | 19552 | 21573 | - | fyuA | 100.0 | 99.9 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 172124 | 172954 | + | gspC | 100.0 | 95.2 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 173194 | 175044 | + | gspD | 100.0 | 97.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 175044 | 176537 | + | gspE | 100.0 | 96.0 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 176537 | 177736 | + | gspF | 100.0 | 96.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 177777 | 178232 | + | gspG | 100.0 | 95.6 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 178269 | 178799 | + | gspH | 100.0 | 96.0 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 178796 | 179167 | + | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 179200 | 179769 | + | gspJ | 100.0 | 97.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 179766 | 180743 | + | gspK | 100.0 | 97.8 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 181058 | 181918 | + | gspL | 100.0 | 97.3 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00002 | 182034 | 182456 | + | gspM | 100.0 | 95.0 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00001 | 25183 | 34674 | - | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 34762 | 40869 | - | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00018 | 77079 | 78131 | - | ompA | 100.0 | 94.3 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00024 | 51877 | 52630 | + | yagV/ecpE | 99.7 | 96.8 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 50310 | 51953 | + | yagW/ecpD | 100.0 | 98.7 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 47795 | 50320 | + | yagX/ecpC | 100.0 | 98.6 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 47101 | 47769 | + | yagY/ecpB | 100.0 | 98.7 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00024 | 46456 | 47043 | + | yagZ/ecpA | 100.0 | 99.3 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 41060 | 42019 | - | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 21705 | 23282 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 42186 | 43988 | + | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 43975 | 45777 | + | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 47078 | 48382 | + | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 23286 | 24089 | - | ybtT | 100.0 | 99.6 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 24086 | 25186 | - | ybtU | 100.0 | 99.5 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 45770 | 47050 | + | ybtX | 100.0 | 99.8 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00024 | 45791 | 46381 | + | ykgK/ecpR | 100.0 | 97.6 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00016 | 49279 | 50707 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00056 | 6303 | 6758 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00056 | 4898 | 5548 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00056 | 4063 | 4479 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00056 | 3203 | 4036 | - | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00015 | 68993 | 69739 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 69739 | 70596 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 72230 | 73417 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 88061 | 88831 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 70610 | 72220 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 80280 | 84133 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 74740 | 75990 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00002 | 204355 | 206254 | - | espL1 | 100.0 | 97.5 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 7262 | 9448 | - | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00069 | 56 | 1109 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00032 | 46249 | 47670 | + | espX1 | 100.0 | 93.3 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 37664 | 39244 | + | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 68743 | 70035 | - | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00032 | 7294 | 8104 | - | espY1 | 99.7 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 28754 | 33002 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00015 | 85796 | 88036 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 73780 | 74736 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 78091 | 78906 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 76089 | 77105 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 77102 | 78094 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00015 | 84351 | 85553 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00053 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00059 | 1110 | 1712 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00059 | 39 | 633 | - | fimE | 99.7 | 99.3 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00053 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00006 | 98307 | 99137 | - | gspC | 100.0 | 95.0 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 96217 | 98067 | - | gspD | 100.0 | 97.3 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 94724 | 96217 | - | gspE | 100.0 | 96.1 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 93525 | 94724 | - | gspF | 100.0 | 96.2 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 93029 | 93484 | - | gspG | 100.0 | 95.6 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 92462 | 92992 | - | gspH | 100.0 | 96.0 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 92094 | 92465 | - | gspI | 100.0 | 95.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 91492 | 92061 | - | gspJ | 100.0 | 97.2 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 90518 | 91495 | - | gspK | 100.0 | 97.8 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 89343 | 90203 | - | gspL | 100.0 | 97.1 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00006 | 88805 | 89227 | - | gspM | 100.0 | 94.1 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00071 | 7016 | 8803 | + | iucA | 100.0 | 94.2 | NP_755502 | (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00071 | 8804 | 9751 | + | iucB | 100.0 | 95.6 | NP_755501 | (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00071 | 9751 | 11493 | + | iucC | 100.0 | 96.0 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00071 | 11490 | 12811 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00071 | 12749 | 15050 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00004 | 75969 | 77009 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00026 | 42110 | 42863 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 40543 | 42186 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 38028 | 40553 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 37334 | 38002 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 36689 | 37276 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 36024 | 36614 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00015 | 49877 | 51305 | + | aslA | 100.0 | 94.0 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00028 | 45439 | 46431 | - | chuU | 100.0 | 97.8 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 44672 | 45472 | - | chuV | 100.0 | 98.1 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 47610 | 48947 | - | chuW | 100.0 | 95.8 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00028 | 46480 | 47103 | - | chuY | 100.0 | 95.2 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00074 | 244 | 1077 | + | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00031 | 31829 | 32575 | - | entA | 100.0 | 95.2 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 32575 | 33432 | - | entB | 100.0 | 97.7 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 35066 | 36253 | - | entC | 100.0 | 98.0 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 50711 | 51481 | + | entD | 100.0 | 94.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 33446 | 35056 | - | entE | 100.0 | 95.6 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 42930 | 46783 | - | entF | 99.2 | 95.5 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 37390 | 38640 | - | entS | 100.0 | 96.1 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00035 | 18791 | 20689 | + | espL1 | 100.0 | 98.7 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00057 | 17740 | 19926 | + | espL4 | 100.0 | 97.8 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 219334 | 220473 | - | espR3 | 100.0 | 94.5 | NP_288394 | (espR3) Type III secretion system effector espR3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 221297 | 222406 | - | espR4 | 97.3 | 84.4 | NP_288396 | (espR4) Type III secretion system effector espR4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 56526 | 57947 | + | espX1 | 100.0 | 96.9 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00069 | 1 | 1275 | - | espX4 | 80.7 | 96.5 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 17117 | 17839 | - | espY1 | 96.0 | 93.2 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00026 | 153 | 722 | - | espY2 | 100.0 | 98.6 | NP_285765 | (espY2) Type III secretion system effector EspY2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00003 | 32205 | 33764 | - | espY3 | 99.2 | 98.7 | NP_286160 | (espY3) Type III secretion system effector EspY3 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00041 | 27499 | 31737 | - | fdeC | 99.7 | 93.3 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00031 | 48446 | 50686 | + | fepA | 100.0 | 96.5 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 36430 | 37386 | + | fepB | 100.0 | 97.8 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 40741 | 41556 | + | fepC | 100.0 | 97.1 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 38739 | 39755 | + | fepD | 100.0 | 96.7 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 39752 | 40744 | + | fepG | 100.0 | 94.7 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00031 | 47001 | 48203 | - | fes | 100.0 | 96.8 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00081 | 15577 | 16188 | - | fimA | 100.0 | 88.4 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00066 | 1120 | 1722 | - | fimB | 100.0 | 97.7 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 14211 | 14936 | - | fimC | 100.0 | 98.6 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 11508 | 14144 | - | fimD | 100.0 | 98.4 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00066 | 49 | 643 | - | fimE | 99.7 | 99.2 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 10968 | 11501 | - | fimF | 100.0 | 97.6 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 10452 | 10955 | - | fimG | 100.0 | 98.0 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 9530 | 10441 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00081 | 14973 | 15512 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00049 | 30592 | 32613 | + | fyuA | 100.0 | 99.5 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 17492 | 26983 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 11297 | 17404 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00098 | 2142 | 3929 | + | iucA | 100.0 | 100.0 | NP_755502 | (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00098 | 3930 | 4877 | + | iucB | 100.0 | 99.9 | NP_755501 | (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00098 | 4877 | 6619 | + | iucC | 100.0 | 99.9 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00098 | 6616 | 7953 | + | iucD | 100.0 | 99.9 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00098 | 7875 | 10154 | + | iutA | 100.0 | 99.7 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00032 | 15561 | 16613 | - | ompA | 100.0 | 95.2 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00028 | 50564 | 52546 | + | shuA | 100.0 | 99.3 | YP_405019 | (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00028 | 52595 | 53623 | + | shuS | 100.0 | 98.5 | YP_405020 | (shuS) heme/hemoglobin transport protein ShuS [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00028 | 48967 | 49959 | - | shuT | 100.0 | 97.6 | YP_405017 | (shuT) periplasmic binding protein ShuT [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00028 | 47103 | 47597 | - | shuX | 100.0 | 98.2 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00049 | 10147 | 11106 | + | ybtA | 100.0 | 99.4 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 28884 | 30461 | + | ybtE | 100.0 | 99.9 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 8178 | 9980 | - | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 6389 | 8191 | - | ybtQ | 100.0 | 99.6 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 3784 | 5088 | - | ybtS | 100.0 | 99.5 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 28077 | 28880 | + | ybtT | 100.0 | 99.6 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 26980 | 28080 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00049 | 5116 | 6396 | - | ybtX | 100.0 | 99.6 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00016 | 49279 | 50707 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00035 | 40481 | 40936 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 41691 | 42341 | + | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 42760 | 43176 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00035 | 43203 | 44036 | + | csgG | 100.0 | 83.3 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00012 | 77381 | 78127 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 78127 | 78984 | - | entB | 100.0 | 98.0 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 80618 | 81805 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 96449 | 97219 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 78998 | 80608 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 88668 | 92521 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 83128 | 84378 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00057 | 18427 | 20325 | + | espL1 | 100.0 | 97.6 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00056 | 19357 | 21543 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00044 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00013 | 48323 | 49458 | - | espR4 | 99.6 | 84.4 | NP_288396 | (espR4) Type III secretion system effector espR4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00006 | 144224 | 145645 | + | espX1 | 100.0 | 95.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00019 | 8865 | 10445 | + | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00019 | 39944 | 41236 | - | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00006 | 105270 | 106081 | - | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00017 | 58929 | 63177 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00012 | 94184 | 96424 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 82168 | 83124 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 86479 | 87294 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 84477 | 85493 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 85490 | 86482 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00012 | 92739 | 93941 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00020 | 46364 | 48385 | - | fyuA | 100.0 | 100.0 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 51994 | 61485 | - | irp1 | 100.0 | 99.8 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 61573 | 67680 | - | irp2 | 100.0 | 99.8 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00072 | 7015 | 8802 | + | iucA | 100.0 | 94.2 | NP_755502 | (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00072 | 8803 | 9750 | + | iucB | 100.0 | 95.6 | NP_755501 | (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00072 | 9750 | 11492 | + | iucC | 100.0 | 96.0 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00072 | 11489 | 12810 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00072 | 12748 | 15049 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00004 | 103766 | 104806 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00017 | 72284 | 73037 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00017 | 70717 | 72360 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00017 | 68202 | 70727 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00017 | 67508 | 68176 | + | yagY/ecpB | 100.0 | 97.9 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00017 | 66863 | 67450 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00020 | 67871 | 68830 | - | ybtA | 100.0 | 99.9 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 48516 | 50093 | - | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 68997 | 70799 | + | ybtP | 100.0 | 99.6 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 70786 | 72588 | + | ybtQ | 100.0 | 99.8 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 73889 | 75193 | + | ybtS | 100.0 | 97.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 50097 | 50900 | - | ybtT | 100.0 | 99.8 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 50897 | 51997 | - | ybtU | 100.0 | 99.7 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00020 | 72581 | 73861 | + | ybtX | 100.0 | 97.7 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00017 | 66198 | 66788 | + | ykgK/ecpR | 100.0 | 97.0 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00147 | 4955 | 5700 | + | entA | 99.2 | 80.4 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00147 | 4094 | 4945 | + | entB | 99.2 | 81.7 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00300 | 127 | 898 | + | fepC | 94.6 | 80.7 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00009 | 58424 | 60445 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 45324 | 54815 | + | irp1 | 100.0 | 99.8 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 39129 | 45236 | + | irp2 | 100.0 | 99.8 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00011 | 18165 | 19235 | - | ompA | 100.0 | 83.8 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00142 | 10793 | 11546 | + | yagV/ecpE | 99.7 | 85.4 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00142 | 9224 | 10867 | + | yagW/ecpD | 100.0 | 88.7 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00142 | 6709 | 9234 | + | yagX/ecpC | 100.0 | 87.3 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00142 | 6015 | 6683 | + | yagY/ecpB | 100.0 | 87.9 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00142 | 5368 | 5951 | + | yagZ/ecpA | 99.3 | 90.1 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00009 | 37979 | 38938 | + | ybtA | 100.0 | 99.9 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 56716 | 58293 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 36010 | 37812 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 34221 | 36023 | - | ybtQ | 100.0 | 99.9 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 31616 | 32920 | - | ybtS | 100.0 | 97.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 55909 | 56712 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 54812 | 55912 | + | ybtU | 100.0 | 99.6 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00009 | 32948 | 34228 | - | ybtX | 100.0 | 97.7 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00142 | 4713 | 5293 | + | ykgK/ecpR | 98.3 | 86.2 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00083 | 2493 | 3921 | + | aslA | 100.0 | 97.4 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00053 | 25876 | 26904 | + | chuS | 100.0 | 98.0 | NP_756169 | (chuS) heme oxygenase ChuS [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00053 | 22247 | 23239 | - | chuT | 100.0 | 99.4 | NP_756175 | (chuT) periplasmic heme-binding protein ChuT [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00053 | 18719 | 19711 | - | chuU | 100.0 | 99.1 | NP_756179 | (chuU) heme permease protein ChuU [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00053 | 17952 | 18752 | - | chuV | 100.0 | 98.4 | NP_756180 | (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00053 | 20890 | 22227 | - | chuW | 100.0 | 97.9 | NP_756176 | (chuW) Putative oxygen independent coproporphyrinogen III oxidase [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00053 | 19760 | 20383 | - | chuY | 100.0 | 96.3 | NP_756178 | (chuY) ChuY [Chu (VF0227)] [Escherichia coli CFT073] |
| contig00045 | 28463 | 31507 | - | cnf1 | 100.0 | 99.9 | CAA50007 | (cnf1) cytotoxic necrotizing factor 1 [CNF-1 (VF0240)] [Escherichia coli str. E-B35] |
| contig00023 | 46133 | 46588 | - | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00131 | 67 | 717 | + | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00131 | 1136 | 1552 | + | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00131 | 1579 | 2412 | + | csgG | 100.0 | 82.8 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00002 | 30548 | 31294 | - | entA | 100.0 | 96.4 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 31294 | 32151 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 33785 | 34972 | - | entC | 100.0 | 98.4 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 49429 | 50199 | + | entD | 100.0 | 93.9 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 32165 | 33775 | - | entE | 100.0 | 96.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 41648 | 45501 | - | entF | 99.3 | 96.3 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 36109 | 37359 | - | entS | 100.0 | 96.3 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00004 | 472 | 2370 | - | espL1 | 100.0 | 96.0 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00016 | 49067 | 50317 | + | espR1 | 99.3 | 94.7 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00042 | 21241 | 22821 | + | espX4 | 100.0 | 96.0 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00074 | 15179 | 15927 | + | espY1 | 99.5 | 94.4 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00059 | 7955 | 8524 | + | espY2 | 100.0 | 94.0 | NP_285765 | (espY2) Type III secretion system effector EspY2 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00043 | 1 | 2266 | + | espY4 | 93.9 | 88.8 | NP_290352 | (espY4) Type III secretion system effector EspY4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 44495 | 48736 | - | fdeC | 99.8 | 92.0 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00002 | 47164 | 49404 | + | fepA | 100.0 | 97.9 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 35149 | 36105 | + | fepB | 100.0 | 98.2 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 39460 | 40275 | + | fepC | 100.0 | 97.7 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 37458 | 38474 | + | fepD | 100.0 | 96.5 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 38471 | 39463 | + | fepG | 100.0 | 94.5 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00002 | 45719 | 46921 | - | fes | 100.0 | 97.0 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00146 | 7502 | 8107 | - | fimA | 100.0 | 92.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00278 | 709 | 1311 | + | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00146 | 6136 | 6861 | - | fimC | 100.0 | 98.5 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00146 | 3433 | 6069 | - | fimD | 100.0 | 98.3 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00278 | 1789 | 2385 | + | fimE | 100.0 | 98.7 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00146 | 2893 | 3426 | - | fimF | 100.0 | 97.4 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00146 | 2377 | 2880 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00146 | 1455 | 2366 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00146 | 6898 | 7437 | - | fimI | 100.0 | 98.3 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00157 | 1 | 1741 | + | fyuA | 86.1 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00055 | 17448 | 18278 | + | gspC | 100.0 | 94.7 | YP_404599 | (gspC) general secretion pathway protein C [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 18518 | 20368 | + | gspD | 100.0 | 96.1 | YP_404600 | (gspD) general secretion pathway protein D [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 20368 | 21861 | + | gspE | 100.0 | 94.6 | YP_404601 | (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 21861 | 23060 | + | gspF | 100.0 | 94.5 | YP_404602 | (gspF) general secretion pathway protein F [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 23101 | 23556 | + | gspG | 100.0 | 96.3 | YP_404603 | (gspG) general secretion pathway protein G [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 23593 | 24123 | + | gspH | 100.0 | 94.7 | YP_404604 | (gspH) general secretion pathway protein H [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 24120 | 24491 | + | gspI | 100.0 | 92.2 | YP_404605 | (gspI) general secretion pathway protein I [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 24524 | 25093 | + | gspJ | 100.0 | 94.6 | YP_404606 | (gspJ) general secretion pathway protein J [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 25090 | 26067 | + | gspK | 100.0 | 96.5 | YP_404607 | (gspK) general secretion pathway protein K [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 26382 | 27242 | + | gspL | 100.0 | 95.0 | YP_404608 | (gspL) general secretion pathway protein L [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00055 | 27358 | 27779 | + | gspM | 99.8 | 97.4 | YP_404609 | (gspM) general secretion pathway protein M [T2SS (VF0333)] [Shigella dysenteriae Sd197] |
| contig00127 | 5764 | 8838 | + | hlyA | 100.0 | 98.6 | NP_755445 | (hlyA) Hemolysin A [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00127 | 8909 | 10812 | + | hlyB | 89.6 | 99.1 | NP_755448 | (hlyB) Hemolysin B [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00127 | 5078 | 5752 | + | hlyC | 100.0 | 100.0 | NP_755444 | (hlyC) Hemolysin C [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00045 | 32453 | 33889 | - | hlyD | 100.0 | 99.9 | NP_755449 | (hlyD) Hemolysin D [Hemolysin (VF0225)] [Escherichia coli CFT073] |
| contig00099 | 7302 | 9089 | + | iucA | 100.0 | 94.3 | NP_755502 | (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00099 | 9090 | 10037 | + | iucB | 100.0 | 95.7 | NP_755501 | (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00099 | 10037 | 11779 | + | iucC | 100.0 | 96.1 | NP_755500 | (iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00099 | 11776 | 13097 | + | iucD | 98.8 | 96.3 | NP_755499 | (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00099 | 13035 | 15336 | + | iutA | 100.0 | 88.4 | NP_755498 | (iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229)] [Escherichia coli CFT073] |
| contig00085 | 12599 | 14275 | - | kpsD | 100.0 | 97.9 | AAA21682 | (kpsD) KpsD [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00055 | 28837 | 29613 | + | kpsM | 100.0 | 95.1 | AAA24046 | (kpsM) KpsM [K1 capsule (VF0239)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00010 | 78486 | 79333 | - | ompA | 81.5 | 97.8 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00045 | 8346 | 8660 | - | papB | 100.0 | 99.4 | (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073] | |
| contig00045 | 4365 | 6887 | - | papC | 100.0 | 99.7 | NP_755465 | (papC) usher protein PapC [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 3560 | 4165 | - | papD | 100.0 | 99.8 | NP_755464 | (papD) chaperone protein PapD [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 1848 | 2387 | - | papE | 100.0 | 100.0 | NP_755460 | (papE) P pilus minor subunit PapE [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 1273 | 1803 | - | papF | 100.0 | 100.0 | NP_755459 | (papF) P pilus minor subunit PapF [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 219 | 1229 | - | papG | 100.0 | 99.1 | NP_755458 | (papG) P pilus tip adhesin PapG [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 6934 | 7521 | - | papH | 100.0 | 98.0 | NP_755466 | (papH) P pilus termination subunit PapH [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 9065 | 9298 | + | papI | 100.0 | 94.0 | NP_755468 | (papI) regulatory protein PapI [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 2942 | 3523 | - | papJ | 100.0 | 98.6 | NP_755463 | (papJ) P pilus assembly protein PapJ [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00045 | 2396 | 2935 | - | papK | 100.0 | 99.3 | NP_755461 | (papK) P pilus minor subunit PapK [P fimbriae (VF0220)] [Escherichia coli CFT073] |
| contig00458 | 173 | 724 | + | papX | 100.0 | 97.5 | NP_755457 | (papX) PapX protein regulates flagellum synthesis to repress motility [P fimbriae (CVF425)] [Escherichia coli CFT073] |
| contig00053 | 23845 | 25827 | + | shuA | 100.0 | 98.0 | YP_405019 | (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00053 | 20383 | 20877 | - | shuX | 100.0 | 96.6 | YP_405016 | (shuX) shu locus protein ShuX [Shu (VF0256)] [Shigella dysenteriae Sd197] |
| contig00012 | 64148 | 64901 | + | yagV/ecpE | 99.7 | 98.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 62581 | 64224 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 60066 | 62591 | + | yagX/ecpC | 100.0 | 98.5 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 59372 | 60040 | + | yagY/ecpB | 100.0 | 99.0 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00012 | 58727 | 59314 | + | yagZ/ecpA | 100.0 | 99.0 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00329 | 353 | 1997 | + | ybtQ | 91.2 | 99.9 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00227 | 2036 | 3183 | - | ybtS | 88.0 | 97.7 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00440 | 1 | 663 | - | ybtT | 82.5 | 99.8 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00467 | 1 | 1046 | - | ybtX | 81.7 | 99.4 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00488 | 27 | 1055 | - | ybtX | 80.3 | 97.3 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00012 | 58062 | 58652 | + | ykgK/ecpR | 100.0 | 99.7 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00032 | 15069 | 16497 | + | aslA | 100.0 | 92.9 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 128600 | 129055 | + | csgB | 99.8 | 83.6 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00001 | 127195 | 127845 | - | csgD | 100.0 | 81.3 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00001 | 126360 | 126776 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00001 | 125500 | 126333 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00036 | 28650 | 29396 | - | entA | 100.0 | 96.0 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 29396 | 30253 | - | entB | 100.0 | 98.4 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 31887 | 33074 | - | entC | 100.0 | 98.3 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 47718 | 48488 | + | entD | 100.0 | 95.1 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 30267 | 31877 | - | entE | 100.0 | 95.8 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 39937 | 43790 | - | entF | 99.3 | 95.7 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 34397 | 35647 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00086 | 125 | 1545 | + | espX1 | 99.9 | 95.3 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00019 | 18898 | 20478 | + | espX4 | 99.9 | 94.1 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00019 | 49982 | 51274 | - | espX5 | 100.0 | 97.0 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00008 | 94198 | 94994 | - | espY1 | 99.9 | 88.7 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00084 | 24 | 4272 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00036 | 45453 | 47693 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 33437 | 34393 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 37748 | 38563 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 35746 | 36762 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 36759 | 37751 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00036 | 44008 | 45210 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00073 | 12316 | 12927 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00082 | 1110 | 1712 | - | fimB | 100.0 | 98.2 | NP_757239 | (fimB) Type 1 fimbriae Regulatory protein fimB [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00073 | 10950 | 11675 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00073 | 8247 | 10883 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00082 | 39 | 633 | - | fimE | 99.7 | 99.3 | NP_757240 | (fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00073 | 7707 | 8240 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00073 | 7191 | 7694 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00073 | 6269 | 7180 | - | fimH | 100.0 | 97.3 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00073 | 11712 | 12251 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00001 | 54588 | 55628 | - | ompA | 100.0 | 98.1 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00068 | 5970 | 6723 | + | yagV/ecpE | 99.7 | 97.0 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00068 | 4400 | 6046 | + | yagW/ecpD | 100.0 | 98.8 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00068 | 1886 | 4410 | + | yagX/ecpC | 100.0 | 98.7 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00068 | 1192 | 1860 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00068 | 547 | 1134 | + | yagZ/ecpA | 100.0 | 99.0 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Contig | Start | End | Strand | Gene | Coverage | Identity | Accession | Product |
|---|---|---|---|---|---|---|---|---|
| contig00022 | 49173 | 50601 | + | aslA | 100.0 | 93.6 | AAG10151 | (aslA) putative arylsulfatase [AslA (VF0238)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00032 | 8088 | 8543 | + | csgB | 99.8 | 83.8 | NP_460114 | (csgB) minor curlin subunit precursor curli nucleator protein CsgB [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 6681 | 7331 | - | csgD | 100.0 | 81.1 | NP_460113 | (csgD) DNA-binding transcriptional regulator CsgD [curli fibers/thin aggregative fimbriae (AGF) (AI094)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 5846 | 6262 | - | csgF | 99.0 | 81.2 | NP_460111 | (csgF) curli production assembly/transport protein CsgF [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00032 | 4986 | 5819 | - | csgG | 100.0 | 83.5 | NP_460110 | (csgG) curli production assembly/transport protein CsgG [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
| contig00038 | 18008 | 18754 | - | entA | 100.0 | 95.7 | NP_752614 | (entA) 23-dihydro-23-dihydroxybenzoate dehydrogenase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 18754 | 19611 | - | entB | 100.0 | 98.1 | NP_752613 | (entB) isochorismatase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 21245 | 22432 | - | entC | 100.0 | 97.9 | NP_752611 | (entC) isochorismate synthase 1 [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 37076 | 37846 | + | entD | 100.0 | 95.2 | NP_752599 | (entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 19625 | 21235 | - | entE | 100.0 | 95.5 | NP_752612 | (entE) 23-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 29295 | 33148 | - | entF | 99.3 | 95.6 | NP_752604 | (entF) enterobactin synthase multienzyme complex component ATP-dependent [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 23755 | 25005 | - | entS | 100.0 | 95.4 | NP_752609 | (entS) enterobactin exporter iron-regulated [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00025 | 23930 | 25830 | + | espL1 | 100.0 | 97.3 | NP_288154 | (espL1) Type III secretion system effector espL1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 102829 | 105015 | + | espL4 | 100.0 | 97.3 | NP_290644 | (espL4) Type III secretion system effector EspL4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00040 | 25267 | 26320 | + | espR1 | 83.7 | 93.8 | NP_287686 | (espR1) Type III secretion system effector espR1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 69187 | 70608 | - | espX1 | 100.0 | 93.2 | NP_285716 | (espX1) Type III secretion system effector EspX1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 73033 | 74613 | - | espX4 | 99.9 | 93.3 | NP_290672 | (espX4) Type III secretion system effector EspX4 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00015 | 42242 | 43534 | + | espX5 | 100.0 | 97.1 | NP_290699 | (espX5) Type III secretion system effector EspX5 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00005 | 108754 | 109565 | + | espY1 | 99.9 | 87.0 | NP_285753 | (espY1) Type III secretion system effector EspY1 [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 265193 | 269441 | - | fdeC | 99.9 | 94.2 | YP_002390132 | (fdeC) adhesin FdeC [FdeC (VF0506)] [Escherichia coli O45:K1:H7 str. S88] |
| contig00038 | 34811 | 37051 | + | fepA | 100.0 | 96.7 | NP_752600 | (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 22795 | 23751 | + | fepB | 100.0 | 97.5 | NP_752610 | (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 27106 | 27921 | + | fepC | 100.0 | 97.3 | NP_752606 | (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 25104 | 26120 | + | fepD | 100.0 | 96.1 | NP_752608 | (fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 26117 | 27109 | + | fepG | 100.0 | 94.1 | NP_752607 | (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228)] [Escherichia coli CFT073] |
| contig00038 | 33366 | 34568 | - | fes | 100.0 | 96.7 | NP_752602 | (fes) enterobactin/ferric enterobactin esterase [enterobactin (IA019)] [Escherichia coli CFT073] |
| contig00048 | 25238 | 25849 | - | fimA | 100.0 | 88.6 | NP_757241 | (fimA) Type-1 fimbrial protein A chain precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00048 | 23872 | 24597 | - | fimC | 100.0 | 98.9 | NP_757243 | (fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00048 | 21169 | 23805 | - | fimD | 100.0 | 98.6 | NP_757244 | (fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00048 | 20629 | 21162 | - | fimF | 100.0 | 97.9 | NP_757245 | (fimF) FimF protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00048 | 20113 | 20616 | - | fimG | 100.0 | 97.8 | NP_757247 | (fimG) FimG protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00048 | 19191 | 20102 | - | fimH | 100.0 | 97.4 | NP_757248 | (fimH) FimH protein precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00048 | 24634 | 25173 | - | fimI | 100.0 | 98.7 | NP_757242 | (fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221)] [Escherichia coli CFT073] |
| contig00031 | 30503 | 32524 | + | fyuA | 100.0 | 99.8 | NP_405467 | (fyuA) pesticin/yersiniabactin receptor protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 17403 | 26894 | + | irp1 | 100.0 | 99.7 | NP_405471 | (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 11208 | 17315 | + | irp2 | 100.0 | 99.5 | NP_405472 | (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00002 | 219469 | 220509 | - | ompA | 100.0 | 98.0 | AAF37887 | (ompA) outer membrane protein A [OmpA (VF0236)] [Escherichia coli O18:K1:H7 str. RS218] |
| contig00001 | 278552 | 279305 | + | yagV/ecpE | 99.7 | 97.1 | NP_286006 | (yagV/ecpE) E. coli common pilus chaperone EcpE [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 276985 | 278628 | + | yagW/ecpD | 100.0 | 99.1 | NP_286007 | (yagW/ecpD) polymerized tip adhesin of ECP fibers [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 274470 | 276995 | + | yagX/ecpC | 100.0 | 98.8 | NP_286008 | (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 273776 | 274444 | + | yagY/ecpB | 100.0 | 98.1 | NP_286009 | (yagY/ecpB) E. coli common pilus chaperone EcpB [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00001 | 273131 | 273718 | + | yagZ/ecpA | 100.0 | 99.2 | NP_286010 | (yagZ/ecpA) E. coli common pilus structural subunit EcpA [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| contig00031 | 10058 | 11017 | + | ybtA | 100.0 | 99.5 | NP_405473 | (ybtA) transcriptional regulator YbtA [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 28795 | 30372 | + | ybtE | 100.0 | 99.8 | NP_405468 | (ybtE) yersiniabactin siderophore biosynthetic protein [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 8089 | 9891 | - | ybtP | 100.0 | 99.7 | NP_405474 | (ybtP) lipoprotein inner membrane ABC-transporter [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 6300 | 8102 | - | ybtQ | 100.0 | 99.7 | NP_405475 | (ybtQ) inner membrane ABC-transporter YbtQ [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 3695 | 4999 | - | ybtS | 100.0 | 99.6 | NP_405477 | (ybtS) salicylate synthase Irp9 [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 27988 | 28791 | + | ybtT | 100.0 | 99.9 | NP_405469 | (ybtT) yersiniabactin biosynthetic protein YbtT [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 26891 | 27991 | + | ybtU | 100.0 | 100.0 | NP_405470 | (ybtU) yersiniabactin biosynthetic protein YbtU [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00031 | 5027 | 6307 | - | ybtX | 100.0 | 99.5 | NP_405476 | (ybtX) putative signal transducer [Yersiniabactin (VF0136)] [Yersinia pestis CO92] |
| contig00001 | 272466 | 273056 | + | ykgK/ecpR | 100.0 | 96.8 | NP_286011 | (ykgK/ecpR) regulator protein EcpR [ECP (VF0404)] [Escherichia coli O157:H7 str. EDL933] |
| Symbol | Meaning |
|---|---|
| ~ | novel full length allele similar to match |
| ? | partial match to known allele |
| - | allele missing |
| Scheme | ST | 1 | 2 | 3 | 4 | 5 | 6 | 7 | |
|---|---|---|---|---|---|---|---|---|---|
| ID005zero | ecoli | 1193 | adk(14) | fumC(14) | gyrB(10) | icd(200) | mdh(17) | purA(7) | recA(10) |
| ID008 | - | - | |||||||
| ID009 | kpneumoniae | 489 | gapA(18) | infB(22) | mdh(26) | pgi(71) | phoE(98) | rpoB(52) | tonB(51) |
| ID011 | ecoli | 10 | adk(10) | fumC(11) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID013 | ecoli | - | adk(85) | fumC(88) | gyrB(78) | icd(29) | mdh(910?) | purA(58) | recA(725?) |
| ID014at24 | senterica | - | aroC(~622) | dnaN(~603) | hemD(554) | hisD(836) | purE(~690) | sucA(281?) | thrA(695?) |
| ID015at48 | ecoli | 448 | adk(6) | fumC(6) | gyrB(5) | icd(16) | mdh(11) | purA(8) | recA(7) |
| ID015HW | ecoli | 448 | adk(6) | fumC(6) | gyrB(5) | icd(16) | mdh(11) | purA(8) | recA(7) |
| ID016at24 | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID017at48 | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID018at24 | ecoli | 1193 | adk(14) | fumC(14) | gyrB(10) | icd(200) | mdh(17) | purA(7) | recA(10) |
| ID020at24 | cfreundii | - | aspC(171) | clpX(193) | fadD(112) | mdh(172) | arcA(111) | dnaG(84) | lysP(~101) |
| ID021at24 | ecoli | 6438 | adk(6) | fumC(11) | gyrB(103) | icd(113) | mdh(8) | purA(1) | recA(2) |
| ID025I | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID025II | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID025III | - | - | |||||||
| ID026 | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID027 | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID031 | ecoli | 998 | adk(13) | fumC(52) | gyrB(156) | icd(14) | mdh(17) | purA(25) | recA(17) |
| ID032I | ecoli | 131 | adk(53) | fumC(40) | gyrB(47) | icd(13) | mdh(36) | purA(28) | recA(29) |
| ID033I | ecoli | 206 | adk(6) | fumC(7) | gyrB(5) | icd(1) | mdh(8) | purA(18) | recA(2) |
| ID034I | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID034II | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID037 | ecoli | 541 | adk(111) | fumC(23) | gyrB(109) | icd(8) | mdh(8) | purA(8) | recA(2) |
| ID043I | ecoli | 38 | adk(4) | fumC(26) | gyrB(2) | icd(25) | mdh(5) | purA(5) | recA(19) |
| ID045 | ecoli | 847 | adk(6) | fumC(6) | gyrB(5) | icd(26) | mdh(9) | purA(13) | recA(98) |
| ID047 | ecoli | 405 | adk(35) | fumC(37) | gyrB(29) | icd(25) | mdh(4) | purA(5) | recA(73) |
| ID050 | ecoli | 1284 | adk(10) | fumC(4) | gyrB(4) | icd(8) | mdh(8) | purA(13) | recA(73) |
| ID051 | ecoli | - | adk(~6) | fumC(88) | gyrB(983?) | icd(1250?) | mdh(208?) | purA(772?) | recA(62) |
| ID052 | ecoli | 349 | adk(34) | fumC(36) | gyrB(39) | icd(87) | mdh(67) | purA(16) | recA(4) |
| ID057 | ecoli | 3580 | adk(6) | fumC(65) | gyrB(344) | icd(1) | mdh(11) | purA(13) | recA(6) |
| ID058 | ecoli | - | adk(6) | fumC(1509?) | gyrB(979?) | icd(8) | mdh(8) | purA(696?) | recA(2) |
| ID066 | ecoli | 224 | adk(6) | fumC(4) | gyrB(33) | icd(16) | mdh(11) | purA(8) | recA(6) |
| ID070 | ecoli | 44 | adk(10) | fumC(11) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(7) |
| ID073 | ecoli | 3036 | adk(207) | fumC(297) | gyrB(260) | icd(254) | mdh(1) | purA(261) | recA(2) |
| ID081 | ecoli | 1284 | adk(10) | fumC(4) | gyrB(4) | icd(8) | mdh(8) | purA(13) | recA(73) |
| ID096I | kpneumoniae | 39 | gapA(2) | infB(1) | mdh(2) | pgi(4) | phoE(9) | rpoB(1) | tonB(14) |
| ID098 | ecoli | 648 | adk(92) | fumC(4) | gyrB(87) | icd(96) | mdh(70) | purA(58) | recA(2) |
| ID099 | ecoli | 206 | adk(6) | fumC(7) | gyrB(5) | icd(1) | mdh(8) | purA(18) | recA(2) |
| ID24 | ecoli | 656 | adk(10) | fumC(7) | gyrB(4) | icd(8) | mdh(8) | purA(8) | recA(2) |
| Genes | Description | Number |
|---|---|---|
| Core genes | (99% <= strains <= 100%) | 0 |
| Soft core genes | (95% <= strains < 99%) | 129 |
| Shell genes | (15% <= strains < 95%) | 6057 |
| Cloud genes | (0% <= strains < 15%) | 22414 |
| Total genes | (0% <= strains <= 100%) | 28600 |
| Field | Description |
|---|---|
| Region | Numeric code given to insertion sequence (IS) |
| Orientation | The orientation of IS position: Either forward (F) or reverse (F) |
| X-cordinates | The left coordinate of the position |
| Y-coordinates | The right coordinate of the position |
| Gap | The distance between the x and y coordinates |
| CallType | Describes whether a position hit is novel (not in reference) or known (in the reference) |
| LeftGene | Locus tag ID of the gene closest to the left side of the IS position |
| LeftGeneDescription | Description of the gene feature from the left side of the IS position. By default this is the product position |
| RightGene | Locus tag ID of the gene closest to the right side of the IS position |
| RightGeneDescription | Description of the gene feature from the right side of the IS position. By default this is the product position |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 1950788 | 1950789 | novel | b4403 | putative rRNA methyltransferase | b1867 | putative hydrolase |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | 1994808 | 1994814 | -6 | novel | b1914 | DNA-binding transcriptional activator UvrY | b1914 | DNA-binding transcriptional activator UvrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481118 | 2481137 | 19 | novel* | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 1040587 | 1040588 | novel | b4403 | putative rRNA methyltransferase | b0980 | periplasmic phosphoanhydride phosphatase/multiple inositol-polyphosphate phosphatase |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | F | 2192272 | 2192276 | -4 | novel | b2111 | putative fimbrial protein YehD | b2112 | DUF2574 domain-containing protein YehE |
| region_1 | R | -1 | 1207440 | 1207441 | novel | b4403 | putative rRNA methyltransferase | b1153 | e14 prophage; conserved protein YmfQ |
| region_2 | R | -1 | 2471880 | 2471881 | novel | b4403 | putative rRNA methyltransferase | b2355 | CPS-53 (KpLE1) prophage; putative uncharacterized protein YfdL |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | F | 2192277 | 2192301 | 24 | novel* | b2111 | putative fimbrial protein YehD | b2112 | DUF2574 domain-containing protein YehE |
| region_1 | R | -1 | 1207440 | 1207441 | novel | b4403 | putative rRNA methyltransferase | b1153 | e14 prophage; conserved protein YmfQ |
| region_2 | R | -1 | 2471880 | 2471881 | novel | b4403 | putative rRNA methyltransferase | b2355 | CPS-53 (KpLE1) prophage; putative uncharacterized protein YfdL |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 1950795 | 1950796 | novel | b4403 | putative rRNA methyltransferase | b1867 | putative hydrolase |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 2009793 | 2009794 | novel | b4403 | putative rRNA methyltransferase | b1931 | putative SOS response-associated peptidase YedK |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481079 | 2481166 | 87 | novel* | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 3861012 | 3861013 | novel | b4403 | putative rRNA methyltransferase | b3680 | putative DNA-binding transcriptional regulator YidL |
| region_2 | R | -1 | 3864565 | 3864566 | novel | b4403 | putative rRNA methyltransferase | b3684 | putative DNA-binding transcriptional regulator YidP |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 2082125 | 2082126 | novel | b4403 | putative rRNA methyltransferase | b2010 | D-alanyl-D-alanine carboxypeptidase DacD |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 1427116 | 1427117 | novel | b4403 | putative rRNA methyltransferase | b1368 | Rac prophage; putative prophage tail length tape measure domain-containing protein YnaA |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | 2060961 | 2060970 | -9 | novel | b1987 | DNA-binding transcriptional activator Cbl | b1988 | DNA-binding transcriptional dual regulator Nac |
| region_2 | F | 2990166 | 2990175 | -9 | novel | b2849 | protein YqeK | b2849 | protein YqeK |
| region_3 | F | 3414054 | 3414067 | -13 | novel | b3265 | multidrug efflux pump membrane fusion lipoprotein AcrE | b3265 | multidrug efflux pump membrane fusion lipoprotein AcrE |
| region_4 | R | 3838044 | 3838053 | -9 | novel | b3659 | putative arabinose exporter | b3659 | putative arabinose exporter |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | F | 2256055 | 2256065 | 10 | novel | b2163 | putative DNA-binding transcriptional regulator YeiL | b2164 | putative pseudouridine transporter |
| region_1 | R | 2996594 | 2997421 | 827 | novel* | b2860 | IS2 insertion element protein InsB | b2861 | IS2 insertion element repressor InsA |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | 735041 | 735067 | 26 | novel* | b0703 | conserved protein, rhs-like YbfO | b0703 | conserved protein, rhs-like YbfO |
| region_2 | F | 2860407 | 2860413 | -6 | novel | b2734 | phosphoprotein phosphatase 2 | b2734 | phosphoprotein phosphatase 2 |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | F | 1362334 | 1362344 | -10 | novel | b1299 | DNA-binding transcriptional repressor PuuR | b1299 | DNA-binding transcriptional repressor PuuR |
| region_2 | R | 1474974 | 1474982 | -8 | novel | b1406 | pyridoxine 4-dehydrogenase | b1406 | pyridoxine 4-dehydrogenase |
| region_3 | F | 3414054 | 3414067 | -13 | novel | b3265 | multidrug efflux pump membrane fusion lipoprotein AcrE | b3265 | multidrug efflux pump membrane fusion lipoprotein AcrE |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 361882 | 361883 | novel | b4403 | putative rRNA methyltransferase | b0343 | lactose permease |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | R | -1 | 2045798 | 2045799 | novel | b4403 | putative rRNA methyltransferase | b1978 | inverse autotransporter adhesin |
| region_2 | R | -1 | 4537613 | 4537614 | novel | b4403 | putative rRNA methyltransferase | b4310 | N-acetylneuraminate mutarotase |
| Region | Orientation | X-coordinates | Y-coordinates | Gap | CallType | LeftGene | LeftGeneDescription | RightGene | RightGeneDescription |
|---|---|---|---|---|---|---|---|---|---|
| region_1 | FALSE | 2481107 | 2481118 | -11 | novel | b2367 | tripartite efflux pump membrane subunit EmrY | b2367 | tripartite efflux pump membrane subunit EmrY |
If you have used rMAP, please cite:
Sserwadda, I., & Mboowa, G. (2021). rMAP: the Rapid Microbial Analysis Pipeline for ESKAPE bacterial group whole-genome sequence data. Microbial genomics, 7(6), 10.1099/mgen.0.000583. https://doi.org/10.1099/mgen.0.000583
The philosophy of rMAP was built on the foundation of already pre-existing tools. As a token of gratitude to the authors of those numerous tools, please also cite: